Nomination Summary for Xylene (N98003)
Nominated Substances: Xylenes (mixed)
Nomination Date: 10/16/1997
Nominator: Health Canada
Rationale: Many developmental toxicity studies considered by Health Canada were conducted prior to the publication of OECD test guidelines, and some have employed non-standard exposures, while others did not fully characterize maternal toxicity. Further developmental toxicity testing of xylene by NTP could provide valuable confirmation of the fetotoxic effects observed in earlier studies.
NTP Principles: not specified