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Nomination Summary for Chromium picolinate (N98015)

Nominated Substances: Chromium picolinate, Chromium picolinate monohydrate

Nomination Date: 06/19/1998

Nominator: Private Individual

Rationale: Chromium picolinate is being marketed as a dietary supplement used for weight loss. A study conducted in 1995 by Dartmouth College & George Washington University found that chromium picolinate caused significant chromosome damage to Chinese hamster ovary cells when the rodents were exposed to a non-toxic dose. Damage was found to be dose-dependent.

NTP Principles: 2

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

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CASRN: 14639-25-9

Agent Name: Chromium picolinate

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CASRN: 27882-76-4

Agent Name: Chromium picolinate monohydrate