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Nomination Summary for 5,6-Benzoflavone (N99017)

Nominated Substances: 5,6-Benzoflavone

Nomination Date: 04/14/1999

Nominator: NCI

Rationale: 5,6-Benzoflavone is a potent inducer of P450 1A enzymes in the family of microsomal mixed function oxidases. It has not been tested for carcinogenicity and may exhibit reproductive toxicity.

NTP Principles: 2, 4

Agents and Status

The following information relates to the specific agent and may include history from earlier or later nominations for this same agent.

CASRN: 6051-87-2

Agent Name: 5,6-Benzoflavone