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Emetine hydrochloride (316-42-7)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID80424947


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Inadequate Study, Male, Rats
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  • Inadequate Study, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Inadequate Study, Male, Mice
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  • Inadequate Study, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Emetine hydrochloride (316-42-7).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Emetine hydrochloride (316-42-7). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-043 Bioassay of Emetine for Possible Carcinogenicity (CASRN 483-18-1)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Emetine Hydrochloride (316-42-7) in Male Sprague-Dawley Rats Exposed via Intraperitoneal Injection
Evaluation of the Chronic Toxicity and Carcinogenicity of Emetine Hydrochloride (316-42-7) in Female Sprague-Dawley Rats Exposed via Intraperitoneal Injection
Evaluation of the Chronic Toxicity and Carcinogenicity of Emetine Hydrochloride (316-42-7) in Male B6C3F1 Mice Exposed via Intraperitoneal Injection
Evaluation of the Chronic Toxicity and Carcinogenicity of Emetine Hydrochloride (316-42-7) in Female B6C3F1 Mice Exposed via Intraperitoneal Injection

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Emetine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 099294
Summary Data