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Diglycidyl resorcinol ether (101-90-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID2020470


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • Positive, Male, Rats
View
  • Positive, Male, Rats
View
  • Positive, Female, Rats
View
  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Positive, Male, Mice
View
  • Positive, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Rodent Cytogenetics study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Rodent Cytogenetics
CA SCE
  • View
    • Positive (Nonstandard Protocol)
  • View
    • Positive
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Micronucleus - Mice
View
  • Male: Positive
View
  • Male: Negative
An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Drosophila Germ Cell Mutagenicity
SLRL RT
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Diglycidyl resorcinol ether (101-90-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Diglycidyl resorcinol ether (101-90-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-257 Toxicology and Carcinogenesis Studies of Diglycidyl Resorcinol Ether (Technical Grade) (CASRN 101-90-6) In F344/N Rats and B6C3F1 Mice (Gavage Studies)
Canter, D.A., Zeiger, E., Haworth, S., Lawlor, T., Mortelmans, K., and Speck, W. Comparative mutagenicity of aliphatic epoxides in Salmonella Mutation Res. Vol. 172 (1986) 105-138
Shelby, M.D., Erexson, G.L., Hook, G.J., and Tice, R.R. Evaluation of a three-exposure mouse bone marrow micronucleus protocol: Results with 49 chemicals. Environ. Molec. Mutag. Vol. 21 (1993) 160-179
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154
Valencia, R., Mason, J.M., Woodruff, R.C., and Zimmering, S. Chemical mutagenesis testing in Drosophila: III. Results of 48 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 325-348
Gulati, D., Witt, K., Anderson, B., Zeiger, E.,and Shelby, M. Chromosome aberration and sister chromatid exchange test in Chinese hamster ovary cells in vitro III: Results with 27 chemicals Environ. Molec. Mutagen. Vol. 13 (1989) 133-193

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Female B6C3F1 Mice Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Micronucleus Study 367536 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) (101-90-6) in Micronucleus Study A56274 in B6C3F1 Mice
Genetic Toxicity Evaluation of Diglycidyl Resorcinol Ether (DGRE) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 493700
Summary Data