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N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID8020917

Study Results

Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Negative, Male, Rats
View
  • Negative, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4).
Bacterial Mutagenicity
View
  • Positive

Citation Information

NTP. N-(1-Naphthyl)ethylenediamine dihydrochloride (1465-25-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

TR-168 Bioassay of N-(1-Naphthyl)ethylenediamine Dihydrochloride for Possible Carcinogenicity (CASRN 1465-25-4)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702

Study Data

Protocol

Toxicity and Carcinogenicity Studies

Evaluation of the Chronic Toxicity and Carcinogenicity of N-(1-Naphthyl)ethylenediamine Dihydrochloride (1465-25-4) in Male F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N-(1-Naphthyl)ethylenediamine Dihydrochloride (1465-25-4) in Female F344 Rats Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N-(1-Naphthyl)ethylenediamine Dihydrochloride (1465-25-4) in Male B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity of N-(1-Naphthyl)ethylenediamine Dihydrochloride (1465-25-4) in Female B6C3F1 Mice Exposed via Dosed Feed
Individual Animal Data
Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of N-(1-Naphthyl)ethylenediamine Dihydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 579654
Summary Data

NTP Data Collections