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Mirex (2385-85-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7020895


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Male, Rats
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  • Clear Evidence, Male, Rats
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  • Clear Evidence, Female, Rats
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  • Clear Evidence, Female, Rats

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to Mirex (2385-85-5).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Mirex (2385-85-5).
Bacterial Mutagenicity
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  • Negative

Citation Information


NTP. Mirex (2385-85-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-313 Toxicology and Carcinogenesis Studies of Mirex (1,1a,2,2,3,3a,4,5,5,5a,5b,6-Dodecachlorooctahydro-1,3,4-metheno-1H-cyclobuta[cd]pentalene) (CASRN 2385-85-5) in F344/N Rats (Feed Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Mirex (2385-85-5) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Mirex (2385-85-5) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Mirex (2385-85-5) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of Mirex (2385-85-5) in Female F344 Rats Exposed via Dosed Feed

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Mirex in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 109625
Summary Data