3-Chloromethylpyridine hydrochloride (6959-48-4)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6020309
Study Results
Chronic Bioassay Level of Evidence
Rats | |
---|---|
View
|
|
View
|
Mice | |
---|---|
View
|
|
View
|
Genetic Toxicology
Rodent Cytogenetics |
---|
CA |
|
Micronucleus - Mice |
---|
View
|
Mammalian Cell Mutagenicity |
---|
View
|
View
|
View
|
Mammalian Cell Cytogenetics | |
---|---|
CA | SCE |
|
|
Drosophila Germ Cell Mutagenicity | |
---|---|
SLRL | RT |
|
Bacterial Mutagenicity |
---|
View
|
Publications
TR-095
Bioassay of 3-(Chloromethyl)pyridine Hydrochloride for Possible Carcinogenicity (CASRN 6959-48-4)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I. Results for nine compounds. Environ. Mutagen. Vol. 9 (1987) 143-160
Woodruff, R.C., Mason, J.M., Valencia, R., and Zimmering, S. Chemical mutagenesis testing in Drosophila: V. Results of 53 coded compounds tested for the National Toxicology Program. Environ. Mutagen. Vol. 7 (1985) 677-702
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloromethylpyridine Hydrochloride (6959-48-4) in Male F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloromethylpyridine Hydrochloride (6959-48-4) in Female F344 Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloromethylpyridine Hydrochloride (6959-48-4) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of 3-Chloromethylpyridine Hydrochloride (6959-48-4) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 3-Chloromethylpyridine Hydrochloride (6959-48-4) in Micronucleus Study A85363 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 3-Chloromethylpyridine Hydrochloride in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 490641
Summary Data
- G06 - Ames Summary Data (131 KB)