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Pentachlorodibenzofuran (57117-31-4)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7030066


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
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  • Some Evidence, Female, Rats

Citation Information


NTP. Pentachlorodibenzofuran (57117-31-4). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-525 Toxicology and Carcinogenesis Studies of 2,3,4,7,8-Pentachlorodibenzofuran (PeCDF) (CASRN 57117-31-4) in Female Harlan Sprague-Dawley Rats (Gavage Studies)
Frawley R, DeVito M, Walker NJ, Birnbaum L, White K Jr, Smith M, Maynor T, Recio L, Germolec D. Relative potency for altered humoral immunity induced by polybrominated and polychlorinated dioxins/furans in female B6C3F1/N mice. Toxicol Sci. 2014 Jun;139(2):488-500. doi: 10.1093/toxsci/kfu041. Epub 2014 Apr 8. PMID: 24713691

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C96007B) of TEF (Dioxin Mixture) (TEFDIOXINMIX) in Harlan Sprague-Dawley Rats Exposed via Gavage. NTP Special Study
Evaluation of the Chronic Toxicity and Carcinogenicity (C96007F) of TEF (PECDF) Pentachlorodibenzofuran (57117-31-4) in Sprague-Dawley Rats Exposed via Gavage. NTP Special Study
Evaluation of the Chronic Toxicity and Carcinogenicity (C96007B) of TEF (Dioxin Mixture) (TEFDIOXINMIX) in Harlan Sprague-Dawley Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C96007F) of TEF (PECDF) Pentachlorodibenzofuran (57117-31-4) in Harlan Sprague-Dawley Rats Exposed via Gavage

Other NTP Studies


Toxicokinetic Evaluation (S0623) of 2,3,4,7,8-pentachlorodibenzofuran (DTXSID7030066) in Rat
Data