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4-Vinyl-1-cyclohexene diepoxide (106-87-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0020604


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Mammalian Cell Mutagenicity
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  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to 4-Vinyl-1-cyclohexene diepoxide (106-87-6).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. 4-Vinyl-1-cyclohexene diepoxide (106-87-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-362 Toxicology and Carcinogenesis Studies of 4-Vinyl-1-cyclohexene Diepoxide (CASRN 106-87-6) in F344/N Rats and B6C3F1 Mice (Dermal Studies)
Mortelmans, K., Haworth, S., Lawlor, T., Speck, W., Tainer, B., and Zeiger, E. Salmonella mutagenicity tests. II. Results from the testing of 270 chemicals Environ. Mutagen. Vol. 8 (Suppl 7) (1986) 1-119
McGregor, D., Brown, A., Cattanach, P., Edwards, I., McBride, D., Riach, C., and Caspary, W. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay: III. 72 coded chemicals. Environ. Molec. Mutagen. Vol. 12 (1988) 85-154

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity (C60139A) of 4-Vinyl-1-cyclohexene Diepoxide (106-87-6) in F344/N Rats Exposed via Topical Application
Evaluation of the Chronic Toxicity and Carcinogenicity (C60139A) of 4-Vinyl-1-cyclohexene Diepoxide (106-87-6) in B6C3F1 Mice Exposed via Topical Application