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N-Nitrosodiphenylamine (86-30-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6021030


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Positive, Male, Rats
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  • Positive, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Negative, Male, Mice
View
  • Negative, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N-Nitrosodiphenylamine (86-30-6).
Mammalian Cell Mutagenicity
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  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N-Nitrosodiphenylamine (86-30-6).
Mammalian Cell Cytogenetics
CA SCE
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N-Nitrosodiphenylamine (86-30-6).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. N-Nitrosodiphenylamine (86-30-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-164 Bioassay of N-Nitrosodiphenylamine for Possible Carcinogenicity (CASRN 86-30-6)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1984) Reproducibility of microbial mutagenicity assays. I. Tests with Salmonella typhimurium and Escherichia coli using a standardized protocol. Environ. Mutagen. 6 (Suppl. 2): 1-251.

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of N-Nitrosodiphenylamine (86-30-6) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Nitrosodiphenylamine (86-30-6) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Nitrosodiphenylamine (86-30-6) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Nitrosodiphenylamine (86-30-6) in Female B6C3F1 Mice Exposed via Dosed Feed