U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

p-Chloro-a,a,a-trifluorotoluene (98-56-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7024821


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Micronucleus - Mice
View
  • Male: Positive
    Female: Equivocal
An overview of Genetic Toxicology Micronucleus Rats study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Micronucleus - Rats
View
  • Male: Equivocal
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to p-Chloro-a,a,a-trifluorotoluene (98-56-6).
Bacterial Mutagenicity
View
  • Negative
View
  • Negative

Citation Information


NTP. p-Chloro-a,a,a-trifluorotoluene (98-56-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-594 Toxicology and Carcinogenesis Studies of p-Chloro-α,α,α-trifluorotoluene (CAS No. 98-56-6) in Sprague Dawley Rats (Hsd: Sprague Dawley SD) and B6C3F1/N Mice (Inhalation Studies)
TOX-14 Toxicity Studies of p-Chloro-alpha,alpha,alpha-Trifluorotoluene Administered in Corn Oil and alpha-Cyclodextrin to F344/N Rats and B6C3F1 Mice in 14-Day Comparative Gavage Studies
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C10472) of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Harlan Sprague-Dawley Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C10472) of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C10472B) of p-Chloro-a,a,a-trifluorotoluene (98-56-6 ) in Harlan Sprague-Dawley Rats Exposed via Whole Body Respiratory Exposure
Study Tables
Individual Animal Data
Evaluation of the Chronic Toxicity and Carcinogenicity (C10472B) of p-Chloro-a,a,a-trifluorotoluene (98-56-6 ) in B6C3F1 Mice Exposed via Whole Body Respiratory Exposure
Study Tables
Individual Animal Data

Genetic Toxicology Studies


Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Micronucleus Study G10472 in Harlan Sprague-Dawley Rats
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene (98-56-6) in Micronucleus Study G10472B in B6C3F1 Mice
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 176994
Summary Data
Genetic Toxicity Evaluation of p-Chloro-a,a,a-trifluorotoluene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G10472C
Summary Data