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Propylene (115-07-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5021205


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to Propylene (115-07-1).
Mammalian Cell Mutagenicity
View
  • Negative
An overview of Genetic Toxicology Drosophila Germ Cell Mutagenicity study conclusions related to Propylene (115-07-1).
Drosophila Germ Cell Mutagenicity
SLRL
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Propylene (115-07-1).
Bacterial Mutagenicity
View
  • Positive

Citation Information


NTP. Propylene (115-07-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-272 Toxicology and Carcinogenesis Studies of Propylene (CASRN 115-07-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)
McGregor, D., Brown, A.G., Cattanach, P., Edwards, I., McBride, D., Riach, C., Shepherd, W., and Caspary, W. Responses of the L5178Y mouse lymphoma forward mutation assay: V. Gases and vapors. Environ. Molec. Mutagen. Vol. 17 (1991) 122-129
Foureman, P., Mason, J.M., Valencia, R., Zimmering, S. Chemical Mutagenesis Testing in Drosophila. X. Results of 70 coded compounds tested for the National Toxicology Program. Environ. Molec. Mutagen. Vol. 23 (1994) 208-227

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of Propylene (115-07-1) in Male F344 Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Propylene (115-07-1) in Female F344 Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Propylene (115-07-1) in Male B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity of Propylene (115-07-1) in Female B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Propylene in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 779144
Summary Data