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N-Phenyl-2-naphthylamine (135-88-6)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4021131


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
View
  • No Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • No Evidence, Male, Mice
View
  • Equivocal Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Mammalian Cell Mutagenicity study conclusions related to N-Phenyl-2-naphthylamine (135-88-6).
Mammalian Cell Mutagenicity
View
  • Positive
An overview of Genetic Toxicology Mammalian Cell Cytogenetics study conclusions related to N-Phenyl-2-naphthylamine (135-88-6).
Mammalian Cell Cytogenetics
CA SCE
  • View
    • Weakly Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to N-Phenyl-2-naphthylamine (135-88-6).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. N-Phenyl-2-naphthylamine (135-88-6). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-333 Toxicology and Carcinogenesis Studies of N-Phenyl-2-Naphthylamine (CASRN 135-88-6) in F344/N Rats and B6C3F1 Mice (Feed Studies)
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Myhr B.C., McGregor, D., Bowers, L., Riach, C., Brown, A., Edwards, I., McBride, D., Martin, R., and Caspary, W.J. L5178Y mouse lymphoma cell mutation assay results with 41 compounds. Environ. Molec. Mutagen. Vol. 16 (Suppl 18) (1990) 138-167

Study Data


Toxicity and Carcinogenicity Studies


Evaluation of the Chronic Toxicity and Carcinogenicity of N-Phenyl-2-naphthylamine (135-88-6) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Phenyl-2-naphthylamine (135-88-6) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Phenyl-2-naphthylamine (135-88-6) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N-Phenyl-2-naphthylamine (135-88-6) in Female B6C3F1 Mice Exposed via Dosed Feed