N,N'-Dicyclohexylthiourea (1212-29-9)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID9020451
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
Zeiger, E., Anderson, B., Haworth, S., Lawlor, T., and Mortelmans, K. Salmonella mutagenicity tests. IV. Results from the testing of 300 chemicals Environ. Molec. Mutagen. Vol. 11 (Suppl 12) (1988) 1-158
Dunkel, V., Zeiger, E., Brusick, D., McCoy, E., McGregor, D., Mortelmans, K., Rosenkranz, H., and Simmon, V. (1985) Reproducibility of microbial mutagenicity assays. II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escerichia coli. Environ. Mutagen. 7 (Suppl 5): 1-248.
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
McGregor, D.B., Martin, R., Cattanach, P., Edwards, I., McBride, D., and Caspary, W.J. Responses of the L5178Y tk+/tk- mouse lymphoma cell forward mutation assay to coded chemicals. I. Results for nine compounds. Environ. Mutagen. Vol. 9 (1987) 143-160
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N'-Dicyclohexylthiourea (1212-29-9) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N'-Dicyclohexylthiourea (1212-29-9) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N'-Dicyclohexylthiourea (1212-29-9) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of N,N'-Dicyclohexylthiourea (1212-29-9) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of N,N'-Dicyclohexylthiourea in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 240546
Summary Data
- G06 - Ames Summary Data (158 KB)