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Tetrafluoroethylene (116-14-3)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID6021325


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
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  • Clear Evidence, Female, Rats
  • Clear Evidence, Male, Rats
An overview of chronic evidence from Mice studies.
Mice
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  • Clear Evidence, Female, Mice
  • Clear Evidence, Male, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Tetrafluoroethylene (116-14-3).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative

Citation Information


NTP. Tetrafluoroethylene (116-14-3). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-450 Toxicology and Carcinogenesis Studies of Tetrafluoroethylene (CASRN 116-14-3) in F344 Rats and B6C3F1 Mice (Inhalation Studies)
Witt, K.L., Knapton, A., Wehr, C.M., Hook, G.J., Mirsalis, J., Shelby, M.D., and MacGregor, J.T. Micronucleated Erythrocyte Frequency in Peripheral Blood of B6C3F1 Mice from Short-Term, Prechronic, and Chronic Studies of the NTP Carcinogenesis Bioassay Program. Environ. Molec. Mutagen. Vol. 36 (2000) 163-194

Study Data


Toxicity and Carcinogenicity Studies


3-Month Evaluation of the Toxicity (C61596) of Tetrafluoroethylene (116-14-3) in F344/N Rats via Whole Body Respiratory Exposure
3-Month Evaluation of the Toxicity (C61596) of Tetrafluoroethylene (116-14-3) in B6C3F1 Mice via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61596B) of Tetrafluoroethylene (116-14-3) in F344/N Rats via Whole Body Respiratory Exposure
Evaluation of the Chronic Toxicity and Carcinogenicity (C61596B) of Tetrafluoroethylene (116-14-3) in B6C3F1 Mice via Whole Body Respiratory Exposure

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Tetrafluoroethylene (116-14-3) in Micronucleus Study A09684 in B6C3F1 Mice