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Vinpocetine (42971-09-5)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID5023740

Study Results

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Vinpocetine (42971-09-5).
Micronucleus - Mice
View
  • Female: Negative
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Mice study conclusions related to Vinpocetine (42971-09-5).
In Vivo Alkaline Comet Assay - Mice
View
  • Female: Equivocal
An overview of Genetic Toxicology In Vitro Micronucleus study conclusions related to Vinpocetine (42971-09-5).
In Vitro Micronucleus
View
  • Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Vinpocetine (42971-09-5).
Bacterial Mutagenicity
View
  • Negative

Citation Information

NTP. Vinpocetine (42971-09-5). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Related Links

Publications

DART-03 Prenatal Developmental Toxicity Studies of Vinpocetine in Sprague Dawley (Hsd:Sprague Dawley SD) Rats and New Zealand White (Hra:NZW SPF) Rabbits (Gavage Studies)
Embryo-Fetal Development Studies with The Dietary Supplement Vinpocetine in The Rat and Rabbit Natasha Catlin, Suramya Waidyanatha, Eve Mylchreest, Lutfiya Miller-Pinsler, Helen Cunny, Paul Foster, Vicki Sutherland, Barry McIntyre
Birth Defects Research (2018) DOI: https://doi.org/10.1002/bdr2.1207 PMID: 29460393
Systemic Exposure of Vinpocetine in Pregnant Sprague Dawley Rats Following Repeated Oral Exposure: An Investigation of Fetal Transfer Suramya Waidyanatha, Heather Toy, Natalie South, Seth Gibbs, Esra Mutlu, Brian Burback, Barry S.McIntyre, and Natasha Catlin.
Toxicology and Applied Pharmacology (2018) DOI: https://doi.org/10.1016/j.taap.2017.11.011 PMID: 29155086

Study Data

Protocol

Genetic Toxicology Studies

Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in DNA Damage Study G12103D in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in Micronucleus Study G12103C in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Vinpocetine (42971-09-5) in Micronucleus Study G12103E in Human TK6 Cells
Summary and Detailed Data
Genetic Toxicity Evaluation of Vinpocetine in Salmonella/E.coli Mutagenicity Test or Ames Test. Study G12103
Summary Data

Other NTP Studies

Prenatal Developmental Toxicity Dose Range Finding Study (R12103) of Vinpocetine (42971-09-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Prenatal Developmental Toxicity Dose Range Finding (R12103) Study Tables
Prenatal Developmental Toxicity Dose Range Finding (R12103) Individual Animal Data
Prenatal Developmental Toxicity Dose Range Finding Study (R12103D) of Vinpocetine (42971-09-5) in New Zealand White Rabbits Exposed via Gavage
Study Tables
Individual Animal Data
Prenatal Developmental Toxicity Study (R12103B) of Vinpocetine (42971-09-5) in Harlan Sprague-Dawley Rats Exposed via Gavage
Prenatal Developmental Toxicity (R12103B) Study Tables
Prenatal Developmental Toxicity (R12103B) Individual Animal Data
Toxicokinetic Evaluation (K12103) of Vinpocetine (DTXSID5023740) in Rat
Data

NTP Data Collections