U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Share This:

Indole-3-carbinol (700-06-1)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID7031458


Study Results


Chronic Bioassay Level of Evidence

An overview of chronic evidence from Rats studies.
Rats
View
  • No Evidence, Male, Rats
  • Some Evidence, Female, Rats
An overview of chronic evidence from Mice studies.
Mice
View
  • Clear Evidence, Male, Mice
  • No Evidence, Female, Mice

Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Rats study conclusions related to Indole-3-carbinol (700-06-1).
Micronucleus - Rats
View
  • Male: Negative
An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Indole-3-carbinol (700-06-1).
Micronucleus - Mice
View
  • Male: Negative
    Female: Negative
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Indole-3-carbinol (700-06-1).
Bacterial Mutagenicity
View
  • Positive
View
  • Equivocal
View
  • Equivocal

Citation Information


NTP. Indole-3-carbinol (700-06-1). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


TR-584 Toxicology Studies of Indole-3-Carbinol (CASRN 700-06-1) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Indole-3-Carbinol in Harlan Sprague Dawley Rats and B6C3F1/N Mice (Gavage Studies)

Study Data


Toxicity and Carcinogenicity Studies


26-Week Evaluation of the Toxicity (C20010A) of Prevention 4 (Indole-3-carbinol) (700-06-1) in Tg.NK Mice Exposed via Dosed Feed
3-Month Evaluation of the Toxicity (C20006) of Indole-3-carbinol (700-06-1) in F344/N Rats Exposed via Gavage
3-Month Evaluation of the Toxicity (C20006) of Indole-3-carbinol (700-06-1) in B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20006B) of Indole-3-carbinol (700-06-1) in Harlan Sprague-Dawley Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity (C20006B) of Indole-3-carbinol (700-06-1) in B6C3F1 Mice Exposed via Gavage
Special Evaluation of the Toxicity (C20006B) of Indole-3-carbinol (700-06-1) in Sprague-Dawley Rats Exposed via Gavage

Genetic Toxicology Studies


Genetic Toxicity Evaluation of Indole-3-carbinol (700-06-1) in Micronucleus Study A31749 in F344 Rats
Genetic Toxicity Evaluation of Indole-3-carbinol (700-06-1) in Micronucleus Study A94530 in B6C3F1 Mice
Genetic Toxicity Evaluation of Indole-3-carbinol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A34549
Summary Data
Genetic Toxicity Evaluation of Indole-3-carbinol in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A35905
Summary Data
Genetic Toxicity Evaluation of Prevention 4 (Indole-3-carbinol) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A51566
Summary Data