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Emtricitabine (143491-57-0)

DOI: https://doi.org/10.22427/NTP-DATA-DTXSID0040129


Study Results


Genetic Toxicology

An overview of Genetic Toxicology Micronucleus Mice study conclusions related to Emtricitabine (143491-57-0).
Micronucleus - Mice
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  • Male: Positive
    Female: Positive
An overview of Genetic Toxicology In Vivo Alkaline Comet Assay Mice study conclusions related to Emtricitabine (143491-57-0).
In Vivo Alkaline Comet Assay - Mice
View
  • Male: Negative
    Female: Positive
View
  • Female: Positive
An overview of Genetic Toxicology Bacterial Mutagenicity study conclusions related to Emtricitabine (143491-57-0).
Bacterial Mutagenicity
View
  • Negative

Citation Information


NTP. Emtricitabine (143491-57-0). Chemical Effects in Biological Systems (CEBS). Research Triangle Park, NC (USA): National Toxicology Program (NTP).

Publications


Hobbs CA, Recio L, Shepard K, Baldetti C, Winters J, Caspary, W, Witt KL. Abstract, presented at the EMS Annual Meeting in Atlanta GA, October 20-24, 2007. Gender-Specific Genotoxicity in Mice Treated with Emtricitabine and Tenofovir as Assessed by the Flow Cytometry Micronucleus and Comet Assays.

Study Data


Genetic Toxicology Studies


Genetic Toxicity Evaluation of Emtricitabine (143491-57-0) in DNA Damage Study F46736B in B6C3F1 Mice
Genetic Toxicity Evaluation of Emtricitabine (143491-57-0) in DNA Damage Study F46736C in B6C3F1 Mice
Genetic Toxicity Evaluation of Emtricitabine (FTC) (143491-57-0) in Micronucleus Study F46736 in B6C3F1 Mice
Genetic Toxicity Evaluation of Emtricitabine (FTC) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study A42705
Summary Data