2,4-Diaminotoluene (95-80-7)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID4020402
Study Results
Chronic Bioassay Level of Evidence
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Genetic Toxicology
Micronucleus - Mice |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
Haworth, S., Lawlor, T., Mortelmans, K., Speck, W., and Zeiger, E. Salmonella mutagenicity test results for 250 chemicals Environ. Mutagen. Vol. 5 (Suppl 1) (1983) 3-142
Loveday, K.S., Anderson, B.E., Resnick, M.A., and Zeiger, E. Chromosome aberration and sister chromatid exchange tests in Chinese hamster ovary cells in vitro V: Results with 46 chemicals Environ. Molec. Mutagen. Vol. 16 (1990) 272-303
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Male F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Female F344 Rats Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Male B6C3F1 Mice Exposed via Dosed Feed
Evaluation of the Chronic Toxicity and Carcinogenicity of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Female B6C3F1 Mice Exposed via Dosed Feed
Genetic Toxicology Studies
Genetic Toxicity Evaluation of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Micronucleus Study 520516 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in Micronucleus Study 571690 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of 2,4-Diaminotoluene (2,4-Toluene Diamine) in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 707834
Summary Data
- G06 - Ames Summary Data (121 KB)
Other NTP Studies
14-Day Immunotoxicity Evaluation (IMM87034) of 2,4-Diaminotoluene (2,4-Toluene Diamine) (95-80-7) in B6C3F1 Mice via Gavage
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (11 kB)
- Host Resistance to B16F10 Melanoma Tumors (4 kB)
- Mixed Leukocyte Response (9 kB)
- Natural Killer Activity (9 kB)
- Organ Weights (39 kB)
- PYB6 Tumor Incidence (15 kB)
- Resistance to Infection with Listeria Monocytogenes (27 kB)
- Resistance to Infection with Streptococcus Pneumoniae (27 kB)
- Reticulocytes (7 kB)
- Serum Complement (CH50) (units/ml) (7 kB)
- T-Dependent AB Response Day 4 (10 kB)
- T-Dependent AB Response Day 5 (9 kB)
2-Week Immunotoxicity Evaluation (IMM86001) of Toluenes (2-4-Diaminotoluene, p-Nitrotoluene, 4-Chloro-o-Phenylenediamine) (TOLUENES) in Female B6C3F1 Mice Exposed via Gavage
B6CF1 Mice Individual and Summary Data
- Hematology (9 kB)
- Host Resistance to B16F10 Melanoma Tumors (6 kB)
- Infection With Plasmodium Yoelii (5 kB)
- Organ Weights (20 kB)
- PYB6 Tumor Incidence (45 kB)
- Resistance to Infection with Listeria Monocytogenes (30 kB)
- Resistance to Infection with Streptococcus Pneumoniae (32 kB)
- T-Dependent AB Response Day 4 (12 kB)