Chloroform (67-66-3)
DOI: https://doi.org/10.22427/NTP-DATA-DTXSID1020306
Study Results
Chronic Bioassay Level of Evidence
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Mice | |
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Genetic Toxicology
Rodent Cytogenetics | |
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CA | SCE |
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Micronucleus - Mice |
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Mammalian Cell Mutagenicity |
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Mammalian Cell Cytogenetics | |
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CA | SCE |
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Bacterial Mutagenicity |
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Publications
Myhr, B.C., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for sixty-three coded chemicals tested at Litton Bionetics, Inc. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 103-194
Mitchell, A.D., Rudd, C.J., and Caspary, W.J. Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Intralaboratory results for 63 coded chemicals tested at SRI International. Environ. Molec. Mutagen. Vol. 12 (Suppl 13) (1988) 37-102
Study Data
Toxicity and Carcinogenicity Studies
Evaluation of the Chronic Toxicity and Carcinogenicity of Chloroform (67-66-3) in Male Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chloroform (67-66-3) in Female Osborne-Mendel Rats Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chloroform (67-66-3) in Male B6C3F1 Mice Exposed via Gavage
Evaluation of the Chronic Toxicity and Carcinogenicity of Chloroform (67-66-3) in Female B6C3F1 Mice Exposed via Gavage
Genetic Toxicology Studies
Genetic Toxicity Evaluation of Chloroform (67-66-3) in Micronucleus Study 142011 in B6C3F1 Mice
Summary and Individual Animal Data
Genetic Toxicity Evaluation of Chloroform in Salmonella/E.coli Mutagenicity Test or Ames Test. Study 749633
Summary Data
- G06 - Ames Summary Data (154 KB)
Other NTP Studies
28-Day Immunotoxicity Evaluation (IMM98002) of Water Disinfection Byproducts (Chloroform) (67-66-3) in B6C3F1 Mice via Dosed Water
B6CF1 Mice Individual and Summary Data
- Absolute Leukocyte Differentials (18 kB)
- Average Water Consumption (55 kB)
- Body Weights (43 kB)
- Hematology (18 kB)
- Macrophage Stimulation (16 kB)
- Mixed Leukocyte Response (12 kB)
- Natural Killer Activity (17 kB)
- Organ Weights (19 kB)
- Reticulocytes (10 kB)
- Serum IgM (10 kB)
- Surface Markers (%) (19 kB)
- Surface Markers (Absol) (18 kB)
- T-Dependent AB Response Day 4 (15 kB)