ICCVAM agencies presented a number of workshops and webinars during 2016 and 2017 to foster collaboration and provide information about alternative testing methods, summarized in the table below.
Meeting Date | Sponsoring Agency (and partner organization) | Meeting Summary |
---|---|---|
Feb 17 – 18, 2016 | NIEHS, EPA | In Vitro to In Vivo Extrapolation for High Throughput Prioritization and Decision MakingParticipants in the workshop (1) reviewed the state of the science to form recommendations on the best practices for using in vitro to in vivo extrapolation in chemical screening and risk decision making, (2) identified areas that require additional data and/or research, and (3) highlighted examples of how best to apply IVIVE in a tiered risk decision-making strategy. Meeting Location: RTP, North Carolina |
Mar – Sep 2016 | NIEHS (PETA International Science Consortium) | Alternative Approaches for Acute Inhalation Toxicity TestingThe webinar series explored and discussed alternative approaches that could replace, reduce, or refine the use of animals for identifying chemicals that may cause acute systemic toxicity when inhaled. The subsequent workshop developed recommendations for advancing new approaches for acute inhalation toxicity testing. Meeting Location: Online/Bethesda, Maryland |
Apr 05 – 06, 2016 | FDA, NIH/NCATS | Assay Development for High Throughput ScreeningThis workshop for scientists involved in assay development for HTS and lead optimization shared best practices and provided advice on robust assay design. Meeting Location: College Park, Maryland |
Jun 20, 2016 | NIH | Bioinformatics SymposiumAttendees at this symposium learned how scientists are using software licensed by the NIH Library Bioinformatics Support Program to analyze, integrate, and annotate data from multiple genomics technologies. Meeting Location: Bethesda, Maryland |
Jul 08, 2016 | EPA, NIEHS, NIH/NCATS | Transform Tox Testing Challenge WorkshopThis workshop featured presentations by Stage 1 winners of the Transform Tox Testing Challenge and provided opportunities to discuss the remainder of the challenge. Meeting Location: RTP, North Carolina |
Jul 21, 2016 | FDA/CDRH | Final Guidance on "Use of International Standard ISO 10993-1, Biological evaluation of medical devices – Part 1: Evaluation and testing within a risk management process"The FDA held this webinar for industry to review the recommendations in this final guidance and to clarify and update how medical device developers may use ISO 10993-1 standard in their premarket submission to determine the potential for an unacceptable adverse biological response resulting from contact of a medical device with the body. Meeting Location: Online |
Sep 06, 2016 | NIH/NCATS | Tissue Chips in Space InitiativeThis webinar, intended for interested investigators, provided an overview of a program to use organ-on-chip platforms to better understand the molecular and cellular basis of human disease in microgravity. Meeting Location: Online |
Sep 16, 2016 | NIH (PLoS Computational Biology) | Computational Biology: Past, Present, and FutureThis overview of current topics in computational biology featured two discussion panels on near-term challenges and opportunities in the field and how computational biology and computing in general will affect human health. Meeting Location: Bethesda, Maryland |
Dec 08, 2016 | NLM | Introduction to ALTBIBThis webinar described and demonstrated the use of ALTBIB, NLM's online resource for alternatives to vertebrate animal use in research and testing. Meeting Location: Online |
Feb – Mar 2017 | NIEHS | Using Informatics to Improve Data Analysis of Chemical Screening Assays Conducted in ZebrafishThis webinar series considered how issues of variability in zebrafish toxicological screening studies might be addressed by use of standardized nomenclature systems, also known as ontologies. Meeting Location: Online |
Jun 26 – 27, 2017 | NIEHS (Human Toxicology Project Consortium) | BioMed21: A Human Pathways Approach to Disease ResearchThis workshop brought representatives from international projects investigating adverse outcome pathways, with the goal of developing recommendations toward fully implementing a human systems-biology platform for understanding disease and improving interventions. Meeting Location: Bethesda, Maryland |
Aug 24, 2017 | FDA/CDRH | CDRH Final Guidance: Qualification of Medical Device Development ToolsThe FDA hosted this webinar for tool developers and stakeholders interested in learning more about the guidance document and the Medical Device Development Tools program. Meeting Location: Online |
Aug – Sep 2017 | NIEHS | Approaches to Genomic Dose-Response ModelingThis webinar series featured four government and academic research groups describing their approaches to genomic dose-response modeling, which uses toxicogenomics data for risk assessment applications. Meeting Location: Online |
Oct 24, 2017 | FDA (Society of Toxicology) | In Vitro to In Vivo Concordance for Toxicity Prediction and Use in Safety AssessmentsThe latest in the series Colloquia on Emerging Toxicological Science: Challenges in Food and Ingredient Safety featured expert reviews on state-of-the-art in vitro technologies for safety assessment and how they are being utilized. Meeting Location: College Park, Maryland |
Oct – Nov 2017 | NIEHS and EPA | Superfund Research Program Risk e-Learning Seminars on Adverse Outcome PathwaysThe webinar series examined how the adverse outcome pathway framework can help support greater use of mechanistic or pathway-based data in risk assessment and regulatory decision making. Meeting Location: Online |
Nov 02, 2017 | NIEHS and EPA | Alternative Test Methods to Reduce Vertebrate Animal Testing under the Toxic Substances Control ActEPA is developing a strategic plan to promote the development and implementation of alternative test methods and strategies to reduce, refine, or replace vertebrate animal testing. This meeting provided an opportunity for public comment on the plan. Meeting Location: Bethesda, Maryland |
Nov 14, 2017 | NIH/National Center for Advancing Translational Sciences | Securing SBIR & STTR Funding: Support for Entrepreneurs and Researchers in BiotechThis webinar provided an overview of programs and funding that support small businesses and technology transfer organizations, including those involved in the development of alternative testing approaches. Meeting Location: Online |
Nov 28 – 30, 2017 | EPA | Continuing Development of Alternative High-Throughput Screens to Determine Endocrine Disruption, Focusing on Androgen Receptor, Steroidogenesis, and Thyroid PathwaysThis meeting of the Federal Insecticide, Fungicide, and Rodenticide Scientific Advisory Panel considered the use of high-throughput assays and computational models in the EPA Endocrine Disruptor Screening Program. Meeting Location: Arlington, Virginia |