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ICCVAM Biennial Report 2018-2019

Biennial Progress Report 2018-2019 Interagency Coordinating Committee on the Validation of Alternative Methods

Update of ToxTutor

NLM updated its online ToxTutor course in August 2018. ToxTutor is a self-paced tutorial that covers the key principles of toxicology and related topics. It provides information on alternatives to animal testing and the state-of-the-science approaches for risk assessments. If a certificate of completion is needed, ToxTutor can be completed through a learning management system. ToxTutor is being used in academic courses and for training in companies and elsewhere. It is approved by some organizations for continuing education contact hours.

The 2018 update of ToxTutor added "The Microbiome" as a new topic, expanded content on alternatives to animal testing and human-on-a-chip testing approaches, and included induced pluripotent stem cells as an emerging approach for toxicity testing. The tutorial also added more content on AOPs and new sections on "Intuitive Toxicology and Risk Communication" (including content on uncertainty) and "Environmental Toxicology, Environmental Health, and One Health."

In December 2019, NLM made changes to web resources as part of the reorganization associated with their current strategic plan. These changes could cause ToxTutor to be relocated in the future. NLM will be conducting webinars and other presentations in 2020 to inform users how they can continue to access web resources.