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ICCVAM Biennial Report 2018-2019

Biennial Progress Report 2018-2019 Interagency Coordinating Committee on the Validation of Alternative Methods

Funding for Studies to Improve iPSC Reproducibility

In December 2019, NIH accepted applications for Small Business Innovation Research grants to develop methods that improve the reproducibility of iPSC derivation, growth, and differentiation. Projects funded under this grant will address the significant variability currently observed in human iPSCs in reprogramming efficiency, differentiation potential, and cell growth and stability, which is limiting the full application of these tools to research and clinical practice. Eleven NIH Institutes and centers are committing funds to this effort.