COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

ICCVAM Logo

ICCVAM Biennial Report 2018-2019

ICCVAM Biennial Report 2018-2019
Menu
https://ntp.niehs.nih.gov/go/891772

Lung-on-a-chip Models to Assess Toxicity of Aerosols

AFRL has developed in vitro lung modeling tools, including lung-on-a-chip models, to enable robust toxicological assessments of aerosolized particulates. These models include technologies to aerosolize, characterize, and monitor dosimetry in real time. They also provide the control necessary to reproduce operational exposure conditions. The lung-on-a-chip models have cyclical stretch capability, simulating the mechanics of breathing, which has been shown to be important in the exposure mechanism. Together, these models and tools provide a platform to assess operationally relevant environmental or engineer toxicant exposures.

Tags: