COVID-19 is an emerging, rapidly evolving situation.

Get the latest public health information from CDC and research information from NIH.

U.S. flag

An official website of the United States government

Dot gov

The .gov means it's official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

ICCVAM Logo

ICCVAM Biennial Report 2018-2019

ICCVAM Biennial Report 2018-2019
Menu
https://ntp.niehs.nih.gov/go/884476

Publication of Paper Outlining Agency Testing Needs in Acute Systemic Toxicity

Understanding the current regulatory use and acceptance of non-animal data is a necessary starting point for future method development, optimization, and validation efforts. Therefore, the ICCVAM Acute Toxicity Workgroup reviewed (Strickland et al. 2018) acute systemic toxicity testing requirements for six U.S. agencies and noted whether there is flexibility in satisfying data needs with methods that replace or reduce animal use. The review informed the development of the Strategic Roadmap for implementing non-animal approaches to assess potential hazards associated with acute exposures to industrial chemicals and medical products.

Tags: