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ICCVAM Biennial Report 2018-2019

Biennial Progress Report 2018-2019 Interagency Coordinating Committee on the Validation of Alternative Methods
https://ntp.niehs.nih.gov/go/884518

Reduction of Animal Use Through Testing Waivers

An article in Regulatory Toxicology and Pharmacology co-authored by ICCVAM co-chair Anna Lowit (Craig et al. 2019) summarizes the activities of EPA's Hazard and Science Policy Council (HASPOC). HASPOC was established in 2012 by the EPA Office of Pesticide Programs to consider requests for waiving animal study requirements for human health risk assessments. Since its inception, HASPOC has evaluated over 1,000 requests to waive animal studies and granted waivers in response to nearly 90% of requests. As of the article’s publication in 2019, these waivers have saved over 200,000 animals, $300 million in study costs, and $6 million in study review costs.

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