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https://ntp.niehs.nih.gov/go/782508

Regulatory Actions for Year 2016

Year Agency Title CASRN
2016 EPA
Trichloroethylene; Regulation of Certain Uses Under TSCA

Trichloroethylene (TCE) is a volatile organic compound widely used in industrial and commercial processes and has some limited uses in consumer and commercial products. EPA identified significant health risks associated with TCE use in aerosol degreasing and for spot cleaning in dry cleaning facilities. EPA has preliminarily determined that these risks are unreasonable risks. To address these unreasonable risks, EPA is proposing under section 6 of the Toxic Substances Control Act (TSCA) to prohibit the manufacture, processing, and distribution in commerce of TCE for use in aerosol degreasing and for use in spot cleaning in dry cleaning facilities; to prohibit commercial use of TCE for aerosol degreasing and for spot cleaning in dry cleaning facilities; to require manufacturers, processors, and distributors, except for retailers of TCE for any use, to provide downstream notification of these prohibitions throughout the supply chain; and to require limited record keeping.

NTP Information Cited

NTP (National Toxicology Program). 2014. Report on Carcinogens, Thirteenth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

  • Type: Proposed Rule
  • December 16, 2016
  • 81 FR 91592
79-34-5
2016 EPA
Formaldehyde Emission Standards for Composite Wood Products

EPA is issuing a final rule to implement the Formaldehyde Standards for Composite Wood Products Act, which added Title VI to the Toxic Substances Control Act (TSCA). The purpose of TSCA Title VI is to reduce formaldehyde emissions from composite wood products, which will reduce exposures to formaldehyde and result in benefits from avoided adverse health effects. This final rule includes formaldehyde emission standards applicable to hardwood plywood, medium-density fiberboard, and particleboard, and finished goods containing these products, that are sold, supplied, offered for sale, or manufactured (including imported) in the United States. This final rule includes provisions relating to, among other things, laminated products, products made with no-added formaldehyde resins or ultra low-emitting formaldehyde resins, testing requirements, product labeling, chain of custody documentation and other recordkeeping requirements, enforcement, import certification, and product inventory sell-through provisions, including a product stockpiling prohibition. This final rule also establishes a third-party certification program for hardwood plywood, medium-density fiberboard, and particleboard and includes procedures for the accreditation of third-party certifiers and general requirements for accreditation bodies and third-party certifiers.

NTP Information Cited

NTP (National Toxicology Program). 2014. Report on Carcinogens, Thirteenth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

  • Type: Final Rule
  • December 12, 2016
  • 81 FR 89674
50-0-0
2016 OEHHA
Chemical Listed Effective October 21, 2016 as Known to the State of California to Cause Cancer: Pentachlorophenol and By-Products of its Synthesis (Complex Mixture)

Effective October 21, 2016, the Office of Environmental Health Hazard Assessment (OEHHA) is adding pentachlorophenol and by-products of its synthesis (complex mixture) to the list of chemicals known to the state to cause cancer for purposes of Proposition 65.

NTP Information Cited
NTP (National Toxicology Program). 2014. Report on Carcinogens, Thirteenth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

  • Type: Notice
  • October 21, 2016
  • Proposition 65
87-86-5
2016 OEHHA
Final Technical Support Document on Updated Public Health Goal for Antimony in Drinking Water

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is announcing the publication of the updated Public Health Goal (PHG) for antimony in drinking water. A PHG is the level of a drinking water contaminant at which adverse health effects are not expected to occur from a lifetime of exposure. The California Safe Drinking Water Act of 1996 requires OEHHA to develop PHGs based exclusively on public health considerations. PHGs published by OEHHA are considered by the State Water Resources Control Board in setting drinking water standards (Maximum Contaminant Levels, or MCLs) for California.

NTP Information Cited
National Toxicology Program (NTP). 1995. NTP Technical Report on the Toxicology and Carcinogenesis Studies of Toxicology and Carcinogenesis Studies of Hydroquinone (CASRN 123-31-9) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 366. https://ntp.niehs.nih.gov/go/tr366abs

National Toxicology Program (NTP). 1992. NTP Technical Report on the Toxicity Studies of Toxicity Studies of Antimony Potassium Tartrate (CASRN 28300-74-5) in F344/N Rats and B6C3F1 Mice (Drinking Water and Intraperitoneal Injection Studies). Research Triangle Park, NC: National Toxicology Program. Toxicity Report 11. https://ntp.niehs.nih.gov/go/tox11abs

  • Type: Notice
  • September 23, 2016
  • Public Health Goals
123-31-9
28300-74-5
2016 VA
Diseases Associated with Exposure to Contaminants in the Water Supply at Camp Lejeune

The Department of Veterans Affairs (VA) proposes to amend its adjudication regulations relating to presumptive service connection to add certain diseases associated with contaminants present in the base water supply at U.S. Marine Corps Base Camp Lejeune (Camp Lejeune), North Carolina, from August 1, 1953 to December 31, 1987. The chemical compounds involved have been associated by various scientific organizations with the development of certain diseases. This proposed rule would establish that veterans, former reservists, and former National Guard members, who served at Camp Lejeune for no less than 30 days (consecutive or nonconsecutive) during this period, and who have been diagnosed with any of eight associated diseases, are presumed to have a service-connected disability for purposes of entitlement to VA benefits. In addition, VA proposes to establish a presumption that these individuals were disabled during the relevant period of service, thus establishing active military service for benefit purposes. Under this proposed presumption, affected former reservists and National Guard members would have veteran status for purposes of entitlement to some VA benefits. This proposed amendment would implement a decision by the Secretary of Veterans Affairs that service connection on a presumptive basis is warranted for claimants who served at Camp Lejeune during the relevant period and for the requisite amount of time and later develop certain diseases. The Secretary’s decision is supported by the conclusions of internationally recognized scientific authorities that strong evidence exists establishing a relationship between exposure to certain volatile organic compounds (VOCs) that were in the water at Camp Lejeune and later development of certain disabilities.

NTP Information Cited
NTP (National Toxicology Program). 2014. Report on Carcinogens, Thirteenth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

National Toxicology Program (NTP). 2015. Report on Carcinogens Monograph on Trichloroethylene (CASRN 79-01-6). Research Triangle Park, NC: National Toxicology Program. RoC Monograph 13. https://doi.org/10.22427/ROC-MGRAPH-13

  • Type: Proposed Rule
  • September 09, 2016
  • 81 FR 62419
79-01-6
2016 HUD
Requirements for Notification, Evaluation and Reduction of Lead-Based Paint Hazards in Federally Owned Residential Property and Housing Receiving Federal Assistance; Response to Elevated Blood Lead Levels

This proposed rule would amend HUD’s lead-based paint regulations on reducing blood lead levels in children under age 6 who reside in federally-owned or -assisted pre-1978 housing and formally adopt the revised definition of ‘‘elevated blood lead levels’’ in children under the age of 6 in accordance with guidance of the Centers for Disease Control and Prevention (CDC), and establish more comprehensive testing and evaluation procedures for the housing where such children reside. In 2012, the CDC issued guidance revising its definition of elevated blood lead level in children under age 6 to be a blood lead level based on the distribution of blood lead levels in the national population. Since CDC’s revision of its definition, HUD has applied the revised definition to funds awarded under its Lead-Based Paint Hazard Control grant program and its Lead Hazard Reduction Demonstration grant program, and has updated its Guidelines for the Evaluation and Control of Lead-Based Paint Hazards in Housing to reflect this definition. CDC is continuing to consider, with respect to evolution of scientific and medical understanding, how best to identify childhood blood lead levels for which environmental interventions are recommended. Through this rule, HUD formally adopts through regulation the CDC’s approach to the definition of ‘‘elevated blood lead levels’’ in children under the age of 6 and addresses the additional elements of the CDC guidance pertaining to assisted housing.

NTP Information Cited
National Toxicity Program (NTP). 2012. Monograph on Health Effects of Low-level Lead. Research Triangle Park, NC: National Toxicology Program. https://ntp.niehs.nih.gov/ntp/ohat/lead/final/monographhealtheffectslowlevellead_newissn_508.pdf 

  • Type: Proposed Rule
  • September 01, 2016
  • 81 FR 60304
7439-92-1
2016 OEHHA
1-Bromopropane Listed Effective August 5, 2016, as Known to the State of California to Cause Cancer

Effective August 5, 2016, the Office of Environmental Health Hazard Assessment (OEHHA) is adding 1-bromopropane (CAS No. 106-94-5) to the list of chemicals known to the state to cause cancer for purposes of Proposition 65.

NTP Information Cited
National Toxicology Program (NTP). 2011. NTP Technical Report on the Toxicology and Carcinogenesis Studies of 1-Bromopropane (CASRN 106-94-5) in F344/N Rats and B6C3F1 Mice (Inhalation Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 564. https://ntp.niehs.nih.gov/go/tr564abs

  • Type: Notice
  • August 05, 2016
  • Proposition 65
106-94-5
2016 OEHHA
Bromodichloroacetic Acid Listed Effective July 29, 2016 as Known to the State of California to Cause Cancer

Effective July 29, 2016, the Office of Environmental Health Hazard Assessment (OEHHA) is adding bromodichloroacetic acid (CAS No. 71133-14-7) to the list of chemicals known to the state to cause cancer for purposes of Proposition 65.

NTP Information Cited
National Toxicology Program (NTP). 2015. NTP Technical Report on the Toxicology Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/NTac Rats and B6C3F1/N Mice (Drinking Water Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 583. https://doi.org/10.22427/NTP-TR-583

  • Type: Notice
  • July 29, 2016
  • Proposition 65
71133-14-7
2016 DOE
Chronic Beryllium Disease Prevention

The Department of Energy (DOE or the Department) is proposing to amend its current chronic beryllium disease prevention program regulation. The proposed amendments would improve and strengthen the current provisions and continue to be applicable to DOE Federal and contractor employees who are, were, or potentially were exposed to beryllium at DOE sites.

NTP Information Cited
NTP (National Toxicology Program). 2014. Beryllium and Beryllium Compounds. Report on Carcinogens. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/ntp/roc/content/profiles/berylliumandberylliumcompounds.pdf

  • Type: Notice of Proposed Rulemaking and Public Hearings
  • June 07, 2016
  • 81 FR 12547
7440-41-7
2016 OEHHA
Notice of Intent to List Bromodichloroacetic Acid

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) intends to list the chemical bromodichloroacetic acid as known to the state to cause cancer under the Safe Drinking Water and Toxic Enforcement Act of 1986.

NTP Information Cited
National Toxicology Program (NTP). 2015. NTP Technical Report on the Toxicology Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/N Rats and B6C3F1/N Mice and Toxicology and Carcinogenesis Studies of Bromodichloroacetic Acid (CASRN 71133-14-7) in F344/NTac Rats and B6C3F1/N Mice (Drinking Water Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 583. https://doi.org/10.22427/NTP-TR-583

  • Type: Notice
  • May 27, 2016
  • Proposition 65
71133-14-7
2016 OEHHA
Styrene Listed Effective April 22, 2016 As Known To The State Of California To Cause Cancer

Effective April 22, 2016, the Office of Environmental Health Hazard Assessment (OEHHA) is adding styrene (CAS No. 100-42-5) to the list of chemicals known to the state to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). The listing of styrene is based on formal identification by the National Toxicology Program (NTP), an authoritative body, that the chemical causes cancer. The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 27, Cal. Code of Regs., section 25306.

NTP Information Cited
NTP (National Toxicology Program). 2011. Report on Carcinogens, Twelfth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

  • Type: Notice
  • April 22, 2016
  • Proposition 65
100-42-5
2016 OEHHA
Proposed Amendment to Section 25705, Specific Regulatory Levels Posing No Significant Risk: Styrene

The listing of styrene is based on formal identification by the National Toxicology Program (NTP), an authoritative body, that the chemical causes cancer. The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 27, Cal. Code of Regs., section 25306.

NTP Information Cited
NTP (National Toxicology Program). 2011. Report on Carcinogens, Twelfth Edition. Research Triangle Park, NC: U.S. Department of Health and Human Services, Public Health Service. https://ntp.niehs.nih.gov/go/roc

  • Type: Notice
  • April 22, 2016
  • Proposition 65
100-42-5
2016 OEHHA
Notice Of Emergency Action To Amend Section 25603.3 Title 27, California Code Of Regulations Warnings For Exposures To Bisphenol A From Canned And Bottled Foods And Beverages

On May 11, 2015, Bisphenol A (BPA) was added to the Proposition 65 list of chemicals known to the state to cause reproductive toxicity based on the female reproductive endpoint. Female reproductive toxicity occurs when a chemical damages any aspect of the female reproductive system. BPA is commonly used in certain linings of metal cans and lids of glass bottles containing food and beverages. Under Proposition 65, one year after the listing, beginning May 11, 2016, warnings are required for all exposures to BPA unless the person causing the exposure can show that the exposure when multiplied by 1,000 times has no observable effect.

NTP Information Cited
National Toxicology Program (NTP). 2008. NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Bisphenol A. Research Triangle Park, NC: Center for the Evaluation of Risks to Human Reproduction, National Toxicology Program. https://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

  • Type: Notice
  • April 19, 2016
  • Proposition 65
80-05-7
2016 OEHHA
Notice Of Proposed Rulemaking, Amendment To Section 25805, Specific Regulatory Levels: Chemicals Causing Reproductive Toxicity - Ethylene Glycol (Ingested)

OEHHA reviewed the studies identified in the NTP-CERHR Monograph that provide the basis for the listing, and conducted a literature search for any other relevant studies or reports published after the NTP-CERHR review was completed. Additional relevant studies were identified and reviewed by OEHHA. This is discussed in more detail in the initial statement of reasons for this proposed regulatory amendment.

NTP Information Cited
National Toxicology Program (NTP). 2004. NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Ethylene Glycol. Research Triangle Park, NC: Center for the Evaluation of Risks to Human Reproduction, National Toxicology Program. https://ntp.niehs.nih.gov/ntp/ohat/egpg/ethylene/eg_monograph.pdf

  • Type: Notice
  • April 08, 2016
  • Proposition 65
107-21-1
2016 EPA
Diflubenzuron; Pesticide Tolerances

This regulation establishes tolerances for residues of diflubenzuron in or on multiple commodities which are identified and discussed later in this document. Interregional Research Project Number 4 (IR–4) requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA).

NTP Information Cited
National Toxicology Program (NTP). 1989. NTP Technical Report on the Toxicology and Carcinogenesis Studies of para-Chloroaniline Hydrochloride (CASRN 20265-96-7) in F344/N Rats and B6C3F1 Mice (Gavage Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 351. https://ntp.niehs.nih.gov/go/tr351abs

  • Type: Final Rule
  • February 12, 2016
  • 81 FR 7466
106-47-8
2016 EPA
Benzyl acetate; Exemption From the Requirement of a Tolerance

This regulation establishes an exemption from the requirement of a tolerance for residues of benzyl acetate (CAS Reg. No. 140–11–4), when used as an inert ingredient (solvent) in pesticide formulations applied to growing crops only under 40 CFR 180.920. Technology Sciences Group, on behalf of the Huntsman Corporation, submitted a petition to EPA under the Federal Food, Drug, and Cosmetic Act (FFDCA), requesting establishment of an exemption from the requirement of a tolerance. This regulation eliminates the need to establish a maximum permissible level for residues of benzyl acetate.

NTP Information Cited
National Toxicology Program (NTP). 1993. NTP Technical Report on the Toxicology and Carcinogenesis Studies of Benzyl Acetate (CASRN 140-11-4) in F344/N Rats and B6C3F1 Mice (Feed Studies). Research Triangle Park, NC: National Toxicology Program. Technical Report 431. https://ntp.niehs.nih.gov/go/tr431abs

  • Type: Final Rule
  • February 12, 2016
  • 81 FR 7473
140-11-4