https://ntp.niehs.nih.gov/go/ntpupdate2020
January - June

January

EPA updates list of alternative test methods, and NIEHS to provide small business funding for genetically diverse toxicity tests.
In the U.S., the substance has been phased out of almost all commercial and industrial products, but it persists in the environment.
An expert panel agreed with findings from a recent National Toxicology Program study on a compound known as oxybenzone.
During a meeting at the National Institutes of Health, scientists said cell-based antibodies could improve experimental quality.
Michael Wyde, Ph.D., analyzed the latest generation of cellular technology and its potential human health effects.
Findings give new insights into the connection between poor air quality and the health of children and mothers.
Experts reviewed research on chronic inflammation, its role in common diseases, and the need for biomarkers and other research directions.
The National Toxicology Program’s Trey Saddler described how problems such as poor air and water quality affect tribal communities.

February

Nicole Kleinstreuer was named Acting Director of the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) on January 1.
Sidney Green will receive the 2020 SOT Founders Award for outstanding leadership in toxicology.
Slides available from ICCVAM webinar on animal-free affinity reagents, webinar demonstrates NICEATM tool for predicting acute oral toxicity, and recent publications.
The National Toxicology Program's Nicole Kleinstreuer talks about the use of artificial intelligence in environmental health research.

March

Webpage available summarizing NICEATM and ICCVAM activities at SOT, plus recent publications.
Experts at a North Carolina State University meeting examined how toxicants may affect brain development.
Christopher Weis and others discussed updating methods to test talc-containing products for asbestos and similar particles.
Exposure to microplastics is widespread and well documented, but health effects are unclear.
Focus is on using approaches more relevant to humans when studying chemicals.
The April 6 event features an international group of researchers and is free to attend in person or watch online.

April

ICE version 3.0 now available, NIEHS to present webinar on grant opportunities for NAM development, NICEATM and ICCVAM scientists featured in SOT virtual meeting webinars, papers due July 31 for special issue of Chemical Research in Toxicology, and EURL ECVAM issues status report on alternatives.
Two National Toxicology Program fellows and three current grantees are among the outstanding scientists honored with 2020 SOT awards.
The Botanical Safety Consortium launches call for diverse groups to join.

May

Registration is open to attend the May 29 virtual meeting.
Registration is open for the May 21 ICCVAM public forum, and a new NICEATM webpage highlights regulatory applications of 3Rs.
Across the institute, researchers are lending their expertise to the fight against the novel coronavirus.
In local seminar, the NIEHS postdoctoral fellow discusses how the chemicals could affect the liver.
Kyle Messier brings his expertise in spatiotemporal statistical models to toxicological studies.

June

Leadership a key theme in ICCVAM public forum; EPA requests public comment on draft risk assessment for antimicrobial chemicals; EURL ECVAM recommends use of nonanimal-derived antibodies; and recent publications.
A mysterious kidney disease and the use of epigenetics to predict health risks were among the topics discussed.
David Berube, an NTP adviser, discussed pandemic communications research. Others presented studies using zebrafish as physiological models.
July - December

July

Registration open for September 2-3 SACATM meeting; EPA releases new approach methods work plan; NICEATM activities at the Society for Birth Defects Research and Prevention annual meeting; slides and video available from ICCVAM public forum; and new tool maps chemical effects on the human body.
Woychik will lead research into environmental influences on human health and serve as director of the National Toxicology Program.
NIEHS encourages grant recipients to participate in the Rapid Acceleration of Diagnostics for Underserved Populations initiative.
The Interagency Coordinating Committee on the Validation of Alternative Methods spotlighted federal efforts to use new research approaches.
The Society for Birth Defects Research and Prevention celebrates work of institute scientists at annual meeting.
Members of the Botanical Safety Consortium discussed the challenges of studying how plant-based diet supplements may affect health.
Bingham’s leadership in occupational safety and Smith’s groundbreaking research into indoor air pollution inspired people around the world.

August

ICCVAM 2018-2019 Biennial Report and ICE Version 3.1 now available, NICEATM and partners present webinar series on animal-free antibodies, and report recommends alternatives to laboratory dog use by VA.
The fourth annual event drew an international audience, with experts discussing social-environmental tradeoffs, climate change, and more.
Early-career scientists gained insight from leaders in industry, government, and academia during the virtual event.
Brandy Beverly discussed how traffic-related air pollution affects pregnant women, and what spurred her interest in science.

September

Virtual SACATM meeting reaches wide audience; Symposium webinar September 30 on kinetically derived maximum dose; NICEATM activities at ASCCT annual meeting; FDA solicits proposals for alternative methods webinar series; FIFRA SAP to meet in September; NICEATM and partners present webinar series on animal-free antibodies; and Recent publications.
Nicole Kleinstreuer spoke with Environmental Factor about recent federal efforts to reduce animal use in chemical safety testing.
The scientific director of the NIEHS Division of the National Toxicology Program recently spoke with a group of international scientists.

October

EPA holds second conference on NAMs for Chemical Safety Testing; NTP activities at ASCCT annual meeting; and presentations available from September 2-3 SACATM meeting.
Reviews of progestogens, paraquat, and neonicotinoid pesticides are among the first of a new type of National Toxicology Program report.
Scientists discussed potential effects on development and reproduction, and ways to improve hazard assessment.
The 2020 meeting of the North Carolina Society of Toxicology included a career panel and presentations by NIEHS early-career scientists.
Experts at federal meeting focus on areas for reducing animal use in testing.
Findings build confidence in the human relevance of data from animal models of cancer.

November

ICE version 3.2 now available. EPA announces guidance to waive toxicity tests; new webpages on metrics and NAMs. OSHA, PHMSA request public input in advance of international meetings.
Help advance environmental health sciences by joining NIEHS. Innovative thinkers committed to scientific excellence should apply by Dec. 21.

December

Presentations and video available from EPA NAMs conference; Publication describes the Tox21 chemical library.
The VA’s research and development office coordinates efforts to find alternatives through participation in a federal interagency group.
Genetics and Environmental Mutagenesis Society fall meeting showcases data science, trainee presentations.Genetics and Environmental Mutagenesis Society fall meeting showcases data science, trainee presentations.