January - June


ALTBIB moves to NTP website; ICCVAM Communities of Practice webinar on mixtures toxicity January 26; and FDA launches pilot program to support novel approaches to drug development.
The NIEHS Division of the National Toxicology Program aims to share findings faster and tackle cardiovascular, neurodevelopmental diseases.
The antibacterial compound, found in consumer products and some drinking water, worsened liver health in diabetic mice fed a high-fat diet.


EPA finalizes guidance to waive toxicity tests on animal skin; New FDA report highlights progress in advancing alternatives; Minutes available from 2020 SACATM meeting; NICEATM and ICCVAM activities at SOT; Report available for 2019 Acute Toxicity Workshop; NICEATM research featured in special issue of Chemical Research in Toxicology.
A pregnant woman’s exposures may affect the baby as well as her own longer-term health.


Update available: EPA list of alternative test methods; EURL ECVAM issues status report on alternatives; Slides and video available from ICCVAM January 26 webinar; Special issue of Frontiers in In Vitro Toxicology on new approach methodologies; Chemical Research in Toxicology special issue focuses on computational toxicology; Workshop report available: Application of NAMs in support of read-across; and New toxicity prediction model provides broader and improved predictions.
Recognition for outstanding NIEHS researchers is in the spotlight during Women’s History Month.
Division of National Toxicology Program initiatives include environmental contributors to cancer, effects of combined chemical exposures.
Federal agencies collaborate on microphysiological systems to accelerate development of new treatments.
Nicole Kleinstreuer co-edited a collection of computational toxicology articles in a special issue of the journal Chemical Research in Toxicology.


NICEATM releases ICE 3.3; DNTP postdoctoral fellow wins SOT specialty section Young Investigator award; NICEATM paper named Paper of the Year by SOT specialty section; and Recent publications.
Science communication, microplastics pollution, cannabis use during pregnancy, and more were discussed by institute scientists and grantees.
More than 500 researchers — from senior scientists to undergraduate students — participated in a virtual NIEHS workshop.
Common goals and collaborative research signify the National Institute for Occupational Safety and Health’s participation in the NTP.


Registration open for ICCVAM Public Forum May 27; CPSC issues proposed guidance on use of alternative methods, Comments due June 14; FDA to hold Science Forum May 26-27; NICEATM paper describes variability in skin irritation data; New review article describes non-animal approaches to eye irritation testing; NICEATM meeting activities.
During almost four decades at the institute, he brought innovation to many complex issues, such as reducing animal use in research.
NIEHS is working with the White House Office of Science and Technology Policy to boost knowledge about emerging contamination issues.
These research programs were front and center at the National Toxicology Program Board of Scientific Counselors meeting.
The freely available CATMoS combines the strengths of 139 different computational approaches to organic chemical screening.


ICCVAM Public Forum held May 27; Save the date for SACATM in September; NICEATM to collaborate with Unilever on development of predictive model for skin sensitization; Paper describes global collaboration to develop predictive models for acute oral toxicity; Video, slides available from spring workshop on use of MPS for COVID research; Abstract submission open for ASCCT annual meeting, deadline July 15; and NICEATM activities at upcoming meetings.
July - December


NICEATM releases ICE 3.4; OECD issues guideline for skin sensitization assessment and other new documents; Kamel Mansouri receives QSAR 2021 Promising Early Career Award; Video available from webinar on MPS database.
NIEHS Division of the National Toxicology Program (DNTP) scientists discussed their efforts to provide timely, human-relevant toxicity data.
Federal agency advancement of nonanimal chemical safety testing methods showcased at May public forum.


NICEATM and ICCVAM activities at World Congress; Slides and video available from ICCVAM Public Forum; ICCVAM Advisory Committee to meet in September - Registration open; Recent publications.
NIEHS researchers and their collaborators developed the recently accepted nonanimal testing method, which will be used globally.


Agenda and other materials available for September 28-29 SACATM meeting; NICEATM presents webinar series on skin sensitization; Kleinstreuer to serve on National Academies panel examining mammalian toxicity tests; NICEATM scientists supporting training on alternatives to animal ase for acute toxicity tests; Article reviews activities of MPS working group.
Experts focused on climate adaptation, health equity, and big data during Aug. 16 event hosted by NIEHS.
NIEHS Division of the National Toxicology Program scientists described related initiatives during Aug. 4 virtual event.
Poster sessions capped their two-month NIEHS experience, and mentors from the institute guided them along the way.


SACATM meeting focuses on ecotoxicity, method validation; NICEATM presents webinar series on skin sensitization; NICEATM contributes to new features in QSAR Toolbox; NICEATM activities at ASCCT annual meeting; Paper describes new and updated ICE tools.
Scientists involved with the Environmental Health Language Collaborative shared challenges, opportunities during workshop hosted by NIEHS.
The Health and Environmental Sciences Institute recognized him for his lifetime of work advancing health equity.
Seventeen experts examined the gut-brain connection and its role in environmental health during two-day NIEHS workshop.


NICEATM releases ICE 3.5. EPA calls for nominations for Board of Scientific Counselors; due by November 12. FDA draft guidance on carcinogenicity testing; comment by December 6. NICEATM activities at ASCCT; NICEATM scientist honored. Recent publications.
Experts at federal meeting stressed importance of human relevance and clear communication.


Skin sensitization webinar December 8. National Academies workshop on NAMs December 9. Free support offered for NIH small business grant applicants; apply by December 10. Publications available from KMD symposium.
The publication, coauthored by institute scientists, provides guidance on systematic reviews, which help to answer key research questions.
Lifetime Achievement Award given to retired toxicologist Barbara Shane, and trainees take home research honors.