Workshop: The Monocyte Activation Test for Pyrogen Testing of Medical Devices
September 18-19, 2018
National Institutes of Health, Bethesda, Maryland
Agenda and meeting materials are posted on the PISC website.
NICEATM and the PETA International Science Consortium (PISC) are co-organizing this workshop to discuss non-animal approaches for pyrogen testing. The workshop will focus on the use of the monocyte activation test (MAT) as a standalone release test for medical devices.
Pyrogens are substances such as bacteria, fungi, and viruses that can produce fever. Medical products for implantation or injection must be shown to be free of pyrogens before use. This workshop will bring together scientists and regulatory authorities from government and industry to review the MAT and discuss ongoing challenges such as identifying material-mediated and other non-endotoxin pyrogens. Participants will also describe industry experience and use of the MAT and identify any issues to be addressed to enable its implementation.
The workshop will be free and open to the public.