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ICCVAM Communities of Practice Webinar 2017

Incorporating Chemical Information: Resources, Limitations, and Characterizing the Domain of Applicability for 21st Century Toxicity Testing

January 24, 2017

Characterizing, Navigating, and Modeling the Chemical Space Using Next-Generation Cheminformatics Methods
Denis Fourches, Ph.D., Department of Chemistry, Bioinformatics Research Center, NCSU

Recent Cheminformatics Development at NCCT Applied to ER, AR, and Physicochemical Properties of Chemicals
Kamel Mansouri, Ph.D., NCCT, EPA

ICCVAM promotes the development and validation of toxicity testing methods that protect human health and the environment while replacing, reducing, or refining animal use. ICCVAM also provides guidance to test method developers and facilitates collaborations that promote the development of new test methods. To address these goals, ICCVAM held a Communities of Practice webinar on “Incorporating Chemical Information: Resources, Limitations, and Characterizing the Domain of Applicability for 21st Century Toxicity Testing.”

This webinar emphasized the importance of understanding the structural and functional diversity of chemicals used in developing and validating alternative approaches to traditional in vivo toxicology test methods. It also featured next generation chemoinformatics techniques that are being used to fully characterize chemical lists and highlight case studies where such techniques have been successfully applied.

View Federal Register notice announcing the webinar (December 29, 2016) – View notice as webpage