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ICCVAM Public Forum: May 2019

Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM): advancing alternatives to animal testing

May 23, 2019
William H. Natcher Conference Center
National Institutes of Health
Bethesda, Maryland, USA

ICCVAM’s goals include promotion of national and international partnerships between governmental and nongovernmental groups, including academia, industry, advocacy groups, and other key stakeholders. To foster these partnerships ICCVAM holds annual public forums to share information and facilitate direct communication of ideas and suggestions from stakeholders.

At this meeting, over 40 attendees and more than 200 webcast viewers heard presentations by ICCVAM members representing eight U.S. agencies on current activities related to the development and validation of alternative test methods and approaches. Presenters described member agency activities to implement the strategic roadmap for establishing new approaches to evaluate the safety of chemicals and medical products in the United States. A key focus was progress made towards reduction and replacement of animal use for acute toxicity tests required by regulatory agencies: acute systemic toxicity, skin and eye irritation, and skin sensitization testing. Public comments submitted to the meeting praised specific actions agencies have taken in the past year to advance the strategic roadmap goals, and suggested additional activities that could support further progress.

Presentations

Welcome and Introductions: Emily Reinke, U.S. Department of Defense, ICCVAM Co-chair

ICCVAM Roadmap and Implementation Plan - Progress Update: Anna Lowit, EPA, ICCVAM Co-chair

NICEATM Update: Nicole Kleinstreuer, NIEHS

Re-envisioning Toxicity Assessment @NTP: Warren Casey, NIEHS

FDA Activities: Suzanne Fitzpatrick, FDA

The NIH Microphysiological Systems Program: Bo Yeon Lee, NCATS

EPA OPP and OPPT Updates: Steven Snyderman, EPA

USDA Animal Welfare Information Center: Kristina Adams, USDA

U.S. Air Force 711th Human Performance Wing - Application of NAMs: Laura Stolle and Lisa Sweeney, Air Force Research Laboratories

U.S. Army Engineer Research and Development Center Update: Natalia Garcia-Reyero Vinas, ERDC

Predictive Toxicology at U.S. Army CCDC CBC: Kyle Glover, CCDC CBC

Department of the Interior Alternative Toxicology Test Methods Activities: Jessica Leet, Department of the Interior

Measurement Assurance Tools - Application to Alternative Test Methods: Elijah Petersen, National Institute of Standards and Technology

OECD Test Guidelines Programme Update: Wanda Hall, EPA

NIEHS SBIR/STTR Program and Toxicity Screening, Testing, and Modeling: Lingamanaidu Ravichandran, NIEHS

Public Comments

People for the Ethical Treatment of Animals (May 9)

Humane Society of the United States/Humane Society Legislative Fund (May 10)

Physicians Committee for Responsible Medicine (May 10)