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Presentations at SOT 2015: 54th Annual Meeting of the Society of Toxicology

Society of Toxicology - 54th Annual Meeting
March 22-26, 2015 - San Diego, CA, USA

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NICEATM Presentations

Workshop Session: The U.S. Tox21 Collaboration: Advances Made and Lessons Learned

Abstract Number 46: Prioritization and Predictive Toxicology: Estrogen Receptor Active Compounds
Presenter: Casey W

Poster Session:  Alternatives to Mammalian Models I: Cardio, Neuro, Developmental

Abstract Number 236: Identification of Chemical Vascular Disruptors during Development Using an Integrative Predictive Toxicology Model, Zebrafish, and In Vitro Functional Angiogenesis Assays
Poster Board Number: 402
Authors: Tal T, Padilla S, Kilty C, Kennedy B, Toimela T, Sarkanen R, Kleinstreuer N, Knudsen T

Poster Session:  Alternatives to Mammalian Models II: Skin, Eye, Liver

Abstract Number 421: ICCVAM Integrated Decision Strategy for Skin Sensitization
Poster Board Number: 108
Authors: Matheson J, Zang Q, Strickland J, Kleinstreuer N, Allen D, Lowit A, Jacobs A, Casey W
Poster
Text version of poster 

Abstract Number 422: In Silico Predictions of Skin Sensitization Using OECD QSAR Toolbox
Poster Board Number: 109
Authors: Strickland J, Choksi N, Allen D, Casey W
Poster Text version of poster 

Poster Session:  Biological Modeling

Abstract Number 757: Application of Reverse Dosimetry to Compare In Vitro and In Vivo Estrogen Receptor Activity
Poster Board Number: 639
Authors: Chang X, Kleinstreuer N, Ceger P, Choksi N, Hsieh J-H, DeVito M, Allen D, Casey W
Poster Text version of poster 

Workshop Session:  The EDSP Screening Battery: A Work in Progress for Prioritizing Compounds for Quantitative Risk Assessment

Abstract Number 868: Use of Computational Toxicology for Integrated Bioactivity–Exposure Prioritization of the EDSP Chemical Universe
Authors: Browne P, Dixon A, Bergfelt D, Green T, Kent R, Lynn S, Touart L, Judson R, Thomas R, Casey W, Kleinstreuer N

Poster Session:  Alternatives to Mammalian Models III

Abstract Number 1179: Correlation of Tox21 and ToxCast In Vitro and Small Model Organism Outcomes to Rat Oral Toxicity
Poster Board Number: 610
Authors: Polk W, Kleinstreuer N, Strickland J, Paris M, Allen D, Casey W
Poster
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Poster Session:  Computational Toxicology and Data Integration I

Abstract Number 1315: Impact of Local Lymph Node Assay Uncertainty on Predictions of a Bayesian Network Integrated Testing Strategy for Skin Sensitization Potency  
Poster Board Number: 212
Authors: Pirone J, Smith M, Strickland J, Casey W, Jaworska J
Poster Text version of poster 

Abstract Number 1335: Using ToxCast/Tox21 Assays and QSAR Modeling to Predict Androgen Receptor Pathway Activity  
Poster Board Number: 232
Authors: Kleinstreuer N, Zang Q, Filer D, Martin M, Houck K, Allen D, Casey W, Judson R
Poster Text version of poster 

Symposium Session:  Incorporating In Vitro Pharmacokinetic Data and Tools into Toxicity Testing and Risk Assessment: State of the Science

NICEATM Director Dr. Warren Casey is co-chair of the session

Abstract Number 1606: Using Reverse Toxicokinetic Models to Correlate In Vitro and In Vivo Estrogen Receptor Activity  
Presenter: Casey W

Platform Session:  Applications of ToxCast/Tox21 Data: Confidence and Predictivity

NICEATM Director Dr. Warren Casey is co-chair of the session

Abstract Number 1684: Using Bioactivity-Based Read-Across (BaBRA) to Characterize the ToxCast Library
Authors: Casey W, Allen D, Kleinstreuer N
Presenter: Kleinstreuer N

Poster Session:  Regulation/Policy

Abstract Number 1911: Using Acute Oral Toxicity Data to Estimate Acute Dermal Hazard Classification and Labeling of Pesticides
Poster Board Number: 511
Authors: Paris M, Strickland J, Allen D, Casey W
Poster
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Poster Session: Computational Toxicology and Data Integration II

Abstract Number 2207: Developing Quantitative Structure–Activity Relationship (QSAR) Models for Effects on Nematode Larval Growth and Zebrafish Embryonic Development
Poster Board Number: 424
Authors: Hsieh J-H, Boyd W, Tice R, Kleinstreuer N, Sedykh A, Franzosa J

Abstract Number 2237: In Silico Prediction of Physicochemical Properties of Environmental Chemicals in Combination of Molecular Fingerprints and Machine Learning Approaches
Poster Board Number: 454
Authors: Zang Q, Mansouri K, Allen D, Kleinstreuer N, Casey W, Judson R
Poster Text version of poster 

Poster Session: Late-Breaking Poster Session 3

Abstract Number 2641: Curation and Analysis of a Rodent Uterotrophic Database: Insights on Data Quality and Reproducibility
Poster Board Number: 346
Authors: Ceger P, Kleinstreuer N, Allen D, Chang X, Strickland J, Zang Q, Hamm J, Phillips E, Jones B, Casey W
Poster
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ICCVAM Committee Activities

ICCVAM Committee member names are indicated in boldface in author lists.

Poster Session:  Alternatives to Mammalian Models I: Cardio, Neuro, Developmental

Abstract Number 254: Organophosphate Flame Retardants Affect Development and Neurotoxicity in Alternative Models
Poster Board Number: 420
Authors: Behl M, Hsieh J-H, Boyd W, Freedman J, Tice R, Shafter T, Mundy W, Hunter S, Jarema K, Padilla S

Roundtable Session:  Assessing Potential Age-Related Sensitivity to Neurotoxicity of Pyrethroids

ICCVAM Co-Chair Dr. Anna Lowit is co-chair of the session

Presentation: Addressing Age-Related Sensitivity to Pyrethroid Neurotoxicity in the Context of Tox21
Presenter: Lowit A

Roundtable Session:  Confronting and Overcoming the Barriers to Sharing Toxicological Research Data for Risk Assessment in the 21st Century

Abstract Number 411: Confronting and Overcoming the Barriers to Sharing Toxicological Research Data for Risk Assessment in the 21st Century
Authors: Woodall G, Miller G, Simeonov A, Becker R, Pope A, Hakkinen P, Zigas P, Rooney A

Workshop Session:  In Vitro Microphysiological Systems—Developing Confidence in Predictive Ability

ICCVAM member Dr. Suzanne Fitzpatrick is co-chair of the session

Abstract Number 1627: In Vitro Microphysiological Systems—Developing Confidence in Predictive Ability
Authors: Bahinski A, Fitzpatrick S

Abstract Number 1632: Determining the Predictive Capability of In Vitro Microphysiological Systems to Answer Critical Regulatory Questions
Presenter: Fitzpatrick S

Poster Session:  Toxicity of Chemical Mixtures

Abstract Number 1384: A Weight-of-Evidence (WOE) Approach to Include Nonchemical Factors in Chemical Mixtures Risk Assessment
Poster Board Number: 317 
Authors: Mumtaz M, Ruiz P, Smith C, Teuschler L

Poster Session:  Nanotoxicology, In Vitro

Abstract Number 1936: Evaluation of an In Vitro Assay for Nanoparticle-Induced Complement Activation
Poster Board Number: 543
Authors: Leakey J, Collins M, Patri A, Howard P

Informational Session:  Risk Communication and Management in the Era of Social Media and the Internet: Serving Society's Needs with Accurate Information

ICCVAM member Dr. Suzanne Fitzpatrick is co-chair of the session

Abstract Number 2025: Risk Communication and Management in the Era of Social Media and the Internet: Serving Society's Needs with Accurate Information
Authors: Hermansky S, Fitzpatrick S, Canady R, Rangan U

Poster Session: Computational Toxicology and Data Integration II

Abstract Number 2223: HTS and SAR Analysis of Chemicals from the Elk River Spill
Poster Board Number: 440
Authors: Auerbach S, Ferguson S, Hsieh J-H, Walker N, Masten S, Wolfe M, Tice R, Bucher J, Choksi N, Svoboda D, Myatt G, Wampole M, Sedykh A, Lawless M, Prous J

Poster Session: Bioinformatics

Abstract Number 2188: A Bioinformatics Pipeline—ArrayTrack for Genomics-Based Molecular Characterization of Foodborne Pathogens
Poster Board Number: 403
Authors: Fang H, Howard P, Xu J, Zhou G, Gong B, Qian F, Harris S, Meehan J, Tong W, Patel I, Gangiredla J, Lampel K, Elkins C, Jackson S

Poster Session: Late-Breaking Poster Session 3

Abstract Number 2647: Gene Selection for Tox21 High-Throughput Transcriptomics
Poster Board Number: 352
Authors: Shah R, Mav D, Svoboda D, Auerbach S, Sipes N, Collins J, Maull E, Bushel P, Merrick B, Paules R, Judson R, Karmaus A, Thomas R, Mendrick D, Gerhold D