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Test Method Evaluations

Descriptions

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Acute Systemic Toxicity

Acute systemic toxicity tests assess the likelihood of chemical or medical products to cause illness following a single exposure. Read about evaluations of approaches that reduce animal use for these tests. Go
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Biologics

Biologics are medical products derived from biological sources. Learn more about methods that use fewer or no animals to evaluate the safety of biologics. Go
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Computational Toxicology

Computational toxicology studies use computer models to better understand and predict toxic effects. Read about NICEATM computational toxicology projects and resources. Go
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Developmental Toxicity

Developmental toxicity tests assess how substances interfere with normal development and impact offspring. Learn more about alternatives to traditional animal studies for developmental toxicity. Go
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Endocrine Disruptors

Endocrine disruptors are substances that mimic or inhibit the function of hormones. Read about non-animal approaches to identify endocrine disruptors. Go
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Immunotoxicity

Immunotoxicity tests include tests to identify potential skin sensitizers. Read about how NICEATM and ICCVAM have developed approaches to identify these substances without using animals. Go
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Ocular & Dermal Irritation

Ocular and dermal irritation tests identify substances that may injure eyes or skin. Learn more about evaluations of non-animal testing approaches. Go
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Pyrogens

Pyrogens are substances that can produce a fever. Learn more about ICCVAM evaluation of test methods proposed as replacements for the rabbit pyrogen test. Go