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Regulatory Actions for Year 1987

Environmental Protection Agency (EPA)

Notice Type Title Summary of Notice NTP Information Cited CASRN
Final Rule Polyamine-epichlorohydrin FDA final rule amending food additive regulations concerning paper and paperboard components.

December 10, 1987 -- 52 FR 46744 		Reference to NCI/NTP bioassay of 1,2-dichloroethane. (TR-055) 107-06-2
Notice CPSC statement of enforcement policy for household products containing methylene chloride.

September 14, 1987 -- 52 FR 34698 		NTP inhalation bioassay showed clear evidence of carcinogenicity in female rats and male and female mice. (TR-306) 75-09-2
Final Rule 2-Ethylhexanol EPA final rule to require a 2-year oncogenicity bioassay under TSCA Section 4.

August 03, 1987 -- 52 FR 28698 		Reference to studies of 2-Ethylhexanol supported by NIEHS. 104-76-7
Proposed Rule Butyl Benzyl Phthalate EPA proposed rule to delete this chemical from SARA Section 313 list of chemicals for which release reporting is required.

July 20, 1987 -- 52 FR 27226 		NTP bioassay results constitute equivocal evidence of carcinogenicity. (TR-213) 85-68-7
Notice Ethylene Bisdithiocarbamate (EBDC) EPA notice of initiation of special review to determine whether regulatory action is required.

July 17, 1987 -- 52 FR 27172 		NTP is currently conducting an oncogenicity study of ETU, a common contaminant, degradation product, and metabolite of EBDC. (TR-388) 96-45-7
Final Rule 1,2,4,5-Tetrachlorobenzene EPA final rule modifying the test substance purity requirements under TSCA Section 4.

July 15, 1987 -- 52 FR 26477 		NTP-identified test material having 99+% purity not available to manufacturers. 95-94-3
Final Rule 8 Volatile Synthetic Organic Chemicals (VOC's) EPA final rule for National Primary Drinking Water Regulations setting maximum contaminant levels and monitoring requirements for 8 VOC's under the Safe Drinking Water Act (SDWA).

July 08, 1987 -- 52 FR 25690 		NTP chronic bioassay of rats and mice showed clear evidence of carcinogenicity of para-dichlorobenzene, TR-319. 106-46-7
Notice Drinking Water EPA notice of 7 substituted contaminants on SDWA list of 83 contaminants.

July 08, 1987 -- 52 FR 25720 		Dibromomethane (proposed for removal from list) is being considered for NTP testing. Ethylbenzene (proposed for addition to list) is being tested by NTP. 100-41-4
106-93-4
Final Rule Fluoroalkenes EPA final rule to require testing under TSCA Section 4.

June 08, 1987 -- 52 FR 21516 		NTP subchronic inhalation study of vinylidene fluoride. 75-38-7
Final Rule Polyhalogenated Dibenzo-p-dioxins and Dibenzofurans (HDD and HDF) EPA final rule under TSCA to require testing for certain chemicals for HDD/HDF contamination.

June 05, 1987 -- 52 FR 21412 		Decabromodiphenyl Oxide, in grade used in NTP research, is exempt from this rule because NTP studies showed equivocal evidence of carcinogenicity in male mice and no evidence in female mice. (TR-309) 1163-19-5
Final Rule 11-Aminoundecanoic Acid EPA final rule promulgating a significant new use rule under TSCA Section 5.

May 28, 1987 -- 52 FR 19860 		NTP bioassay showed limited evidence of carcinogenicity in animals. (TR-216) 2432-99-7
Proposed Rule Cyclohexane EPA proposed rule on test standards and requirements under TSCA Section 4.

May 20, 1987 -- 52 FR 19096 		Reference to study of cyclohexane supported by NIEHS. 110-82-7
Notice 2,4,5-Trichlorophenol EPA notice of intent to cancel registration as active ingredient for all uses.

April 29, 1987 -- 52 FR 15549 		References to several NTP studies of 2,3,7,8-TCDD, a contaminant of 2,4,5-TCP. (TR-209) 1746-01-6
Proposed Rule P-Dichlorobenzene EPA proposed rule to regulate p-dichlorobenzene as a probable human carcinogen under the Safe Drinking Water Act by amending the Maximum Contaminant Level Goal (MCLG).

April 17, 1987 -- 52 FR 12876 		Based upon the results of the above studies and specifically the conclusions of the NTP report (bioassay of p-dichlorobenzene), EPA is proposing to amend the MCLG. TR-319. 106-46-7
Final Rule 8 Polybrominated Biphenyls (PBB's) and Tris EPA final rule promulgating a significant new use rule under TSCA Section 5.

January 26, 1987 -- 52 FR 2699 		Reference to NTP bioassay of polybrominated biphenyl mixture. TR-244. 67774-32-7
Notice Penta­chloro­phenol EPA notice of decision to cancel registrations for all products containing penta­chloro­phenol for all non-wood uses except pulp/paper mill, oil well operations, and cooling tower uses.

January 21, 1987 -- 52 FR 2282 		EPA requested that NTP reexamine female rat liver lesions from NCI study. 87-86-5
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Food and Drug Administration (FDA)

Notice Type Title Summary of Notice NTP Information Cited CASRN
Final Rule Indirect Food Additives FDA final rule allowing use of an additive to paper products which come into contact with food, although the additive may contain minute amounts of methylene chloride as a byproduct of its production.

May 27, 1987 -- 52 FR 19722 		NTP-supported study of methylene chloride showed carcinogenicity in male and female mice. TR-306. 75-09-2
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Occupational Safety and Health Administration (OSHA)

Notice Type Title Summary of Notice NTP Information Cited CASRN
Final Rule Benzene OSHA final rule revising existing occupational standard to reduce PEL (Permissible Exposure Limit) from 10 ppm to 8-hr TWA (time weighted average) of 1 ppm and short-term exposure limit of 5 ppm.

September 11, 1987 -- 52 FR 34460 		NTP 2-year inhalation bioassay; TR-289 71-43-2
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