Regulatory Actions for Year 1987
Environmental Protection Agency (EPA)
| Notice Type | Title | Summary of Notice | NTP Information Cited | CASRN |
|---|---|---|---|---|
| Final Rule | Polyamine-epichlorohydrin |
FDA final rule amending food additive regulations concerning paper and paperboard components. December 10, 1987 -- 52 FR 46744 |
Reference to NCI/NTP bioassay of 1,2-dichloroethane. (TR-055) | 107-06-2 |
| Notice |
CPSC statement of enforcement policy for household products containing methylene chloride. September 14, 1987 -- 52 FR 34698 |
NTP inhalation bioassay showed clear evidence of carcinogenicity in female rats and male and female mice. (TR-306) | 75-09-2 | |
| Final Rule | 2-Ethylhexanol |
EPA final rule to require a 2-year oncogenicity bioassay under TSCA Section 4. August 03, 1987 -- 52 FR 28698 |
Reference to studies of 2-Ethylhexanol supported by NIEHS. | 104-76-7 |
| Proposed Rule | Butyl Benzyl Phthalate |
EPA proposed rule to delete this chemical from SARA Section 313 list of chemicals for which release reporting is required. July 20, 1987 -- 52 FR 27226 |
NTP bioassay results constitute equivocal evidence of carcinogenicity. (TR-213) | 85-68-7 |
| Notice | Ethylene Bisdithiocarbamate (EBDC) |
EPA notice of initiation of special review to determine whether regulatory action is required. July 17, 1987 -- 52 FR 27172 |
NTP is currently conducting an oncogenicity study of ETU, a common contaminant, degradation product, and metabolite of EBDC. (TR-388) | 96-45-7 |
| Final Rule | 1,2,4,5-Tetrachlorobenzene |
EPA final rule modifying the test substance purity requirements under TSCA Section 4. July 15, 1987 -- 52 FR 26477 |
NTP-identified test material having 99+% purity not available to manufacturers. | 95-94-3 |
| Final Rule | 8 Volatile Synthetic Organic Chemicals (VOC's) |
EPA final rule for National Primary Drinking Water Regulations setting maximum contaminant levels and monitoring requirements for 8 VOC's under the Safe Drinking Water Act (SDWA). July 08, 1987 -- 52 FR 25690 |
NTP chronic bioassay of rats and mice showed clear evidence of carcinogenicity of para-dichlorobenzene, TR-319. | 106-46-7 |
| Notice | Drinking Water |
EPA notice of 7 substituted contaminants on SDWA list of 83 contaminants. July 08, 1987 -- 52 FR 25720 |
Dibromomethane (proposed for removal from list) is being considered for NTP testing. Ethylbenzene (proposed for addition to list) is being tested by NTP. | 100-41-4 106-93-4 |
| Final Rule | Fluoroalkenes |
EPA final rule to require testing under TSCA Section 4. June 08, 1987 -- 52 FR 21516 |
NTP subchronic inhalation study of vinylidene fluoride. | 75-38-7 |
| Final Rule | Polyhalogenated Dibenzo-p-dioxins and Dibenzofurans (HDD and HDF) |
EPA final rule under TSCA to require testing for certain chemicals for HDD/HDF contamination. June 05, 1987 -- 52 FR 21412 |
Decabromodiphenyl Oxide, in grade used in NTP research, is exempt from this rule because NTP studies showed equivocal evidence of carcinogenicity in male mice and no evidence in female mice. (TR-309) | 1163-19-5 |
| Final Rule | 11-Aminoundecanoic Acid |
EPA final rule promulgating a significant new use rule under TSCA Section 5. May 28, 1987 -- 52 FR 19860 |
NTP bioassay showed limited evidence of carcinogenicity in animals. (TR-216) | 2432-99-7 |
| Proposed Rule | Cyclohexane |
EPA proposed rule on test standards and requirements under TSCA Section 4. May 20, 1987 -- 52 FR 19096 |
Reference to study of cyclohexane supported by NIEHS. | 110-82-7 |
| Notice | 2,4,5-Trichlorophenol |
EPA notice of intent to cancel registration as active ingredient for all uses. April 29, 1987 -- 52 FR 15549 |
References to several NTP studies of 2,3,7,8-TCDD, a contaminant of 2,4,5-TCP. (TR-209) | 1746-01-6 |
| Proposed Rule | P-Dichlorobenzene |
EPA proposed rule to regulate p-dichlorobenzene as a probable human carcinogen under the Safe Drinking Water Act by amending the Maximum Contaminant Level Goal (MCLG). April 17, 1987 -- 52 FR 12876 |
Based upon the results of the above studies and specifically the conclusions of the NTP report (bioassay of p-dichlorobenzene), EPA is proposing to amend the MCLG. TR-319. | 106-46-7 |
| Final Rule | 8 Polybrominated Biphenyls (PBB's) and Tris |
EPA final rule promulgating a significant new use rule under TSCA Section 5. January 26, 1987 -- 52 FR 2699 |
Reference to NTP bioassay of polybrominated biphenyl mixture. TR-244. | 67774-32-7 |
| Notice | Pentachlorophenol |
EPA notice of decision to cancel registrations for all products containing pentachlorophenol for all non-wood uses except pulp/paper mill, oil well operations, and cooling tower uses. January 21, 1987 -- 52 FR 2282 |
EPA requested that NTP reexamine female rat liver lesions from NCI study. | 87-86-5 |
Food and Drug Administration (FDA)
| Notice Type | Title | Summary of Notice | NTP Information Cited | CASRN |
|---|---|---|---|---|
| Final Rule | Indirect Food Additives |
FDA final rule allowing use of an additive to paper products which come into contact with food, although the additive may contain minute amounts of methylene chloride as a byproduct of its production. May 27, 1987 -- 52 FR 19722 |
NTP-supported study of methylene chloride showed carcinogenicity in male and female mice. TR-306. | 75-09-2 |
Occupational Safety and Health Administration (OSHA)
| Notice Type | Title | Summary of Notice | NTP Information Cited | CASRN |
|---|---|---|---|---|
| Final Rule | Benzene |
OSHA final rule revising existing occupational standard to reduce PEL (Permissible Exposure Limit) from 10 ppm to 8-hr TWA (time weighted average) of 1 ppm and short-term exposure limit of 5 ppm. September 11, 1987 -- 52 FR 34460 |
NTP 2-year inhalation bioassay; TR-289 | 71-43-2 |
