Regulatory Actions for Year 1987

Year	Agency	Title	CASRN

1987	FDA	Cancer-Causing Residues in Edible Products of Food-Producing Animals FDA final rule on procedures and criteria to ensure absence of such residues in animals to which drugs, food additives, or color additives have been administered. NTP Information Cited References to NTP report on chemical carcinogenesis testing and evaluation. Type: Final Rule December 31, 1987 52 FR 49572
1987	EPA	Polyamine-epichlorohydrin FDA final rule amending food additive regulations concerning paper and paperboard components. NTP Information Cited Reference to NCI/NTP bioassay of 1,2-dichloroethane. (TR-055) Type: Final Rule December 10, 1987 52 FR 46744	107-06-2
1987	EPA	CPSC statement of enforcement policy for household products containing methylene chloride. NTP Information Cited NTP inhalation bioassay showed clear evidence of carcinogenicity in female rats and male and female mice. (TR-306) Type: Notice September 14, 1987 52 FR 34698	75-09-2
1987	OSHA	Benzene OSHA final rule revising existing occupational standard to reduce PEL (Permissible Exposure Limit) from 10 ppm to 8-hr TWA (time weighted average) of 1 ppm and short-term exposure limit of 5 ppm. NTP Information Cited NTP 2-year inhalation bioassay; TR-289 Type: Final Rule September 11, 1987 52 FR 34460	71-43-2
1987	EPA	2-Ethylhexanol EPA final rule to require a 2-year oncogenicity bioassay under TSCA Section 4. NTP Information Cited Reference to studies of 2-Ethylhexanol supported by NIEHS. Type: Final Rule August 03, 1987 52 FR 28698	104-76-7
1987	EPA	Butyl Benzyl Phthalate EPA proposed rule to delete this chemical from SARA Section 313 list of chemicals for which release reporting is required. NTP Information Cited NTP bioassay results constitute equivocal evidence of carcinogenicity. (TR-213) Type: Proposed Rule July 20, 1987 52 FR 27226	85-68-7
1987	EPA	Ethylene Bisdithiocarbamate (EBDC) EPA notice of initiation of special review to determine whether regulatory action is required. NTP Information Cited NTP is currently conducting an oncogenicity study of ETU, a common contaminant, degradation product, and metabolite of EBDC. (TR-388) Type: Notice July 17, 1987 52 FR 27172	96-45-7
1987	EPA	1,2,4,5-Tetrachlorobenzene EPA final rule modifying the test substance purity requirements under TSCA Section 4. NTP Information Cited NTP-identified test material having 99+% purity not available to manufacturers. Type: Final Rule July 15, 1987 52 FR 26477	95-94-3
1987	EPA	8 Volatile Synthetic Organic Chemicals (VOC's) EPA final rule for National Primary Drinking Water Regulations setting maximum contaminant levels and monitoring requirements for 8 VOC's under the Safe Drinking Water Act (SDWA). NTP Information Cited NTP chronic bioassay of rats and mice showed clear evidence of carcinogenicity of para-dichlorobenzene, TR-319. Type: Final Rule July 08, 1987 52 FR 25690	106-46-7
1987	EPA	Drinking Water EPA notice of 7 substituted contaminants on SDWA list of 83 contaminants. NTP Information Cited Dibromomethane (proposed for removal from list) is being considered for NTP testing. Ethylbenzene (proposed for addition to list) is being tested by NTP. Type: Notice July 08, 1987 52 FR 25720	100-41-4 106-93-4
1987	EPA	Fluoroalkenes EPA final rule to require testing under TSCA Section 4. NTP Information Cited NTP subchronic inhalation study of vinylidene fluoride. Type: Final Rule June 08, 1987 52 FR 21516	75-38-7
1987	EPA	Polyhalogenated Dibenzo-p-dioxins and Dibenzofurans (HDD and HDF) EPA final rule under TSCA to require testing for certain chemicals for HDD/HDF contamination. NTP Information Cited Decabromodiphenyl Oxide, in grade used in NTP research, is exempt from this rule because NTP studies showed equivocal evidence of carcinogenicity in male mice and no evidence in female mice. (TR-309) Type: Final Rule June 05, 1987 52 FR 21412	1163-19-5
1987	EPA	11-Aminoundecanoic Acid EPA final rule promulgating a significant new use rule under TSCA Section 5. NTP Information Cited NTP bioassay showed limited evidence of carcinogenicity in animals. (TR-216) Type: Final Rule May 28, 1987 52 FR 19860	2432-99-7
1987	FDA	Indirect Food Additives FDA final rule allowing use of an additive to paper products which come into contact with food, although the additive may contain minute amounts of methylene chloride as a byproduct of its production. NTP Information Cited NTP-supported study of methylene chloride showed carcinogenicity in male and female mice. TR-306. Type: Final Rule May 27, 1987 52 FR 19722	75-09-2
1987	EPA	Cyclohexane EPA proposed rule on test standards and requirements under TSCA Section 4. NTP Information Cited Reference to study of cyclohexane supported by NIEHS. Type: Proposed Rule May 20, 1987 52 FR 19096	110-82-7
1987	EPA	2,4,5-Trichlorophenol EPA notice of intent to cancel registration as active ingredient for all uses. NTP Information Cited References to several NTP studies of 2,3,7,8-TCDD, a contaminant of 2,4,5-TCP. (TR-209) Type: Notice April 29, 1987 52 FR 15549	1746-01-6
1987	EPA	P-Dichlorobenzene EPA proposed rule to regulate p-dichlorobenzene as a probable human carcinogen under the Safe Drinking Water Act by amending the Maximum Contaminant Level Goal (MCLG). NTP Information Cited Based upon the results of the above studies and specifically the conclusions of the NTP report (bioassay of p-dichlorobenzene), EPA is proposing to amend the MCLG. TR-319. Type: Proposed Rule April 17, 1987 52 FR 12876	106-46-7
1987	EPA	8 Polybrominated Biphenyls (PBB's) and Tris EPA final rule promulgating a significant new use rule under TSCA Section 5. NTP Information Cited Reference to NTP bioassay of polybrominated biphenyl mixture. TR-244. Type: Final Rule January 26, 1987 52 FR 2699	67774-32-7
1987	EPA	Pentachlorophenol EPA notice of decision to cancel registrations for all products containing pentachlorophenol for all non-wood uses except pulp/paper mill, oil well operations, and cooling tower uses. NTP Information Cited EPA requested that NTP reexamine female rat liver lesions from NCI study. Type: Notice January 21, 1987 52 FR 2282	87-86-5