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Helicobacter pylori (H. pylori): Chronic Infection

Status: Topic Selected for Evaluation

    • Primary Exposures:
      • Gram negative, multi-flagellated bacterium that colonizes the stomach and causes peptic ulcer
      • Bacterium is spread by person-to-person contact especially among family member and routes of exposure include: oral-oral, fecal-oral, iatrogenic, and possibly from contaminated water
      • Risks factors for infection include age, race, socioeconomic status such as crowded living conditions, poor sanitation/hygiene
    • Documents
      • Federal Regiser notice requesting public comment on the draft monograph (May 11, 2018 - PDF HTML)
      • Federal Register notice requesting public comment on nominated substances (January 19, 2012 – PDF HTML)
      • Concept Document
      • Draft RoC Monograph
      • Revised RoC Monograph
      • Final RoC Monograph
    •  Public Comments
    • Meetings, Webinars and Listening Sessions
      • Review of the Concept Document: NTP Board of Scientific Counselors Meeting (April 11, 2016)
  • Submit additional information (such as citations or new studies, scientific issues, nomination of experts, or comments on RoC documents)

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