Scientific Review of Diethanolamine (DEA)
Status: Reviewed but not listed in the Report on Carcinogens (RoC)
Primary Uses or Exposures: DEA is widely used as an intermediate in the production of fatty-acid condensates formulated into soaps and surfactants used in liquid laundry and dishwashing detergents, cosmetics, shampoos, and hair conditioners. DEA also is used as a surface-active agent and corrosion inhibitor in metalworking fluids and as a dispersant in agricultural chemical formulations. Other applications include use in adhesives; anti-static agents; cement and concrete work; coatings; electroplating; printing inks; metal cleaning and lubricating; mining; natural gas treatment; paint and pigments; paper, petroleum, and coal production; polymers and polymer production; rubber processing; soldering flux; textile finishing; and polyurethane production and use; and as an epoxy hardener, a fuel-gelling agent, a pharmaceutical intermediate, and an ointment-emulsifier.
- Appendix A: IARC (2000). Monographs on the Evaluation of Carcinogenic Risks to Humans. Some Industrial Chemicals. V. 77, pp. 349-379.
- Appendix B: NTP (1999). Toxicology and Carcinogenesis Studies of Diethanolamine in F344/N Rats and B6C3F1 Mice (Dermal Studies). TR 478, pp. 5-60.
- Appendix C: NTP (1992). NTP Technical Report on Toxicity Studies of Diethanolamine (CAS No. 111-42-2) Administered Topically and in Drinking Water to F344/N Rats and B6C3F1 Mice. TOX 20, pp. 7-53 and D1-D9.
Meetings and Minutes from Review Groups
- Review Group 1 Review Summary Document for Diethanolamine (December 10, 2001)
- Review Group 2 Review Summary Document for Diethanolamine (May 2, 2002)
- NTP Board of Scientific Counselors RoC Subcommittee Meeting (November 19–20, 2002)
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