Scientific Review of Nitrobenzene
Status: Listed in the Report on Carcinogens (RoC)
Primary Uses or Exposures: Most nitrobenzene (97%) is used in the manufacture of aniline. Miscellaneous uses include the manufacture of benzidine, quinoline, azobenzene, pyroxylin compounds, isocyanates, pesticides, rubber chemicals, pharmaceuticals, and dyes such as nigrosines and magenta. Nitrobenzene is found in soaps and shoe and metal polishes and is used as a solvent for cellulose ester, in modifying esterification of cellulose acetate, and in refining lubricating oils. Nitrobenzene also is used as a solvent in petroleum refining and the synthesis of other organic compounds, such as acetaminophen.
- Appendix A: IARC (1996). Monographs on the Evaluation of Carcinogenic Risks to Humans. Nitrobenzene. In Printing Processes, Printing Inks, Carbon Blacks and Some Nitro Compounds. V 65. pp 381 - 408.
- Review Group 1 Review Summary Document for Nitrobenzene (June 10, 2002)
- Review Group 2 Review Summary Document for Nitrobenzene (October 2, 2002)
- NTP Board of Scientific Counselors RoC Subcommittee Meeting (November 19–20, 2002)
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