National Toxicology Program

National Toxicology Program

Scientific Review of Nitromethane

CASRN 75-52-5
Status: Listed in the Report on Carcinogens (RoC)

Primary Uses or Exposures: Most of the nitromethane produced in the United States (85% to 90%) is used in the synthesis of nitromethane derivatives used as pharmaceuticals, agricultural soil fumigants, and industrial antimicrobials. Nitromethane also is used as a fuel or fuel additive with methanol in racing cars, boats, and model engines. It formerly was used in the explosives industry as a component in a binary explosive formulation with ammonium nitrate and in shaped charges, and it was used as a chemical stabilizer to prevent decomposition of various halogenated hydrocarbons.

Background Documents

Public Comments

Meetings and Minutes from Review Groups

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NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.