https://ntp.niehs.nih.gov/go/717275

RoC Review of o-Toluidine

Substance Overview

CASRN: 95-53-4
Status: RoC: Known to be a human carcinogen
Profile: o-Toluidine (192.44 KB)

Primary Uses or Exposures

  • An arylamine that is synthesized by nitration of toluene.
  • Used as an intermediate to manufacture herbicides, dyes, pigments, rubber chemicals, and some medical products.
  • People are exposed to high levels of o-toluidine via inhalation or through the skin in workplaces that use it.
  • People are exposed to lower levels of o-toluidine from consumer and medical products and cigarettes.
Back to Top

Documents

Documents for o-Toluidine
Date Document
Aug 30, 2012 RoC Concept
Oct 05, 2012 RoC Protocol
Aug 15, 2013 Literature Search and Identified Citations - Preliminary
Aug 30, 2013 Consultant Report: Use of o-Toluidine in Dye Manufacturing
Jul 22, 2014 RoC Monograph - Final (Abstract)

Preferred Citation: National Toxicology Program (NTP). 2014. Report on Carcinogens monograph on ortho-toluidine. Research Triangle Park, NC: National Toxicology Program. RoC Monograph 04. https://doi.org/10.22427/ROC-MGRAPH-04
Back to Top

Meetings & Events

Listing of related events
Date Event Event Type Materials
Dec 12, 2013

Peer Review of Draft RoC Monographs for ortho-Toluidine and Pentachlorophenol

Expert Panels - RoC
Apr 16, 2014

NTP Board of Scientific Counselors Meeting

Board of Scientific Counselors
  • Agenda
  • Meeting Materials

    NTP Board of Scientific Counselors Meeting Meeting Materials
    April 16-18, 2014

    Supplemental materials for some events, meetings, and workshops prior to 2020 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.

      

     

  • Minutes

Supplemental materials for some events, meetings, and workshops prior to 2020 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials.
Back to Top

Public Comments

List of Public Comments for the Report on Carcinogens
Date Received Commenter(s) Affiliation In Response To
Feb 21, 2012 Steven H. Wodka Attorney at Law Jan 19, 2012 Federal Register notice
Sep 23, 2013 Steven H. Wodka Attorney at Law Aug 21, 2013 Federal Register notice
Back to Top

Note on Accessibility: Persons with disabilities or using assistive technology may find some documents are not fully accessible. For assistance, email us or use our contact form and identify the documents/pages for which access is required. We will assist you in accessing the content of these files. NIEHS has helpful information on accessibility.