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RoC Review of o-Toluidine

Substance Overview

CASRN: 95-53-4
Listing Status: Known to be a human carcinogen
Profile: o-Toluidine (196KB)
Fact Sheet: ortho-Toluidine (189KB)

Primary Uses or Exposures

  • An arylamine that is synthesized by nitration of toluene.
  • Used as an intermediate to manufacture herbicides, dyes, pigments, rubber chemicals, and some medical products.
  • People are exposed to high levels of o-toluidine via inhalation or through the skin in workplaces that use it.
  • People are exposed to lower levels of o-toluidine from consumer and medical products and cigarettes.

Documents

Documents for o-Toluidine
Date Document
Aug 30, 2012 Concept Document
Oct 05, 2012 Protocol: Evaluation of Human Cancer Studies
Aug 15, 2013 Preliminary Literature Search and Identified Citations
Aug 30, 2013 Use of o-Toluidine in Dye Manufacturing – Consultant Report
Jul 22, 2014 RoC Monograph

Meetings & Events

Listing of related events
Date Event Event Type Materials
Dec 12, 2013

Peer Review of Draft RoC Monographs for ortho-Toluidine and Pentachlorophenol

Peer Review Panels - RoC Monographs
Apr 16, 2014

NTP Board of Scientific Counselors Meeting

Board of Scientific Counselors
  • Agenda
  • Meeting Materials

    NTP Board of Scientific Counselors Meeting Meeting Materials
    April 16, 2014

    Supplemental materials for meetings and workshops prior to 2015 have been archived. These archived materials frequently include presentations, background materials, and public comments. Email us or use our contact form to request a list or copy of archived materials for the following meeting.  
  • Minutes
Supplemental materials for events, meetings, and workshops prior to 2015 have been archived. These archived materials frequently include presentations, background materials, and public comments. Request a list or copy of archived materials for the following meetings by e-mailing email us or use our contact form.

Public Comments

List of Public Comments for the Report on Carcinogens
Date Received Commenter(s) Affiliation In Response To
Feb 21, 2012 Steven H. Wodka Attorney at Law Jan 19, 2012 Federal Register notice
Sep 23, 2013 Steven H. Wodka Attorney at Law Aug 21, 2013 Federal Register notice

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