Scientific Review of 4,4'-Thiodianiline
Status: Listed in the Report on Carcinogens (RoC)
Primary Uses or Exposures: 4,4'- Thiodianiline was used almost exclusively as a chemical intermediate in the production of three dyes: C.I. mordant yellow 16, milling red G, and milling red FR. However, only C.I. mordant yellow had any commercial significance in the United States; it was used to dye wool and for printing on wool, silk, and cotton. C.I. mordant yellow 16 has been used as an indicator in the United States government's nerve gas detector program.
- Appendix A: IARC (1982). Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Humans. Some Aromatic Amines, Anthraquinones and Nitroso Compounds, and Inorganic Fluorides Used in Drinking Water and Dental Preparations. V 27. pp. 147-154.
- Appendix B: NCI TR 47 (1978). Bioassay of 4,4'-Thiodianiline for Possible Carcinogenicity. DHEW Publication No. 78-847. pp. vii-106.
Meetings and Minutes from Review Groups
- Review Group 1 Review Summary Document (February 6, 2002)
- Review Group 2 Review Summary Document (May 1, 2002)
- NTP Board of Scientific Counselors RoC Subcommittee Meeting (November 19–20, 2002)
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