National Toxicology Program

National Toxicology Program

Growth, Survival, Pathology, and Development and Reproductive Tables for Peer Review

Growth, survival, pathology, and development and reproductive results of rodent toxicology studies for each test article are presented here following internal review by NTP, including peer review of the pathology data by a Pathology Working Group (PWG). These data are reported in NTP report series including Toxicology (TOX) Reports of short-term or subchronic studies, Technical Reports (TR) of long-term or chronic studies, and results using Genetically Modified Models (GMM) and Developmental and Reproductive Toxicology (DART) studies.

The table below contains test articles for which data from NTP studies are now available. The table also provides links to draft reports, as available, on these studies for the appropriate NTP series. Information about upcoming public peer review meetings is available on the Technical Reports Peer Review Panel meeting page. The draft reports will undergo external peer review prior to publication. Following peer review and consideration of the comments, NTP will prepare final reports and post them to the NTP website by report type, with the abstract web page providing links to the final pathology, body eights, and survival results.

Note: The pathology, developmental and reproductive, body weight, survival, and other data posted on this website have not been through peer review or published in a NTP report and should not be construed to represent any agency determination or policy.

Test Article Study Tables Last Update Review
Abrasive Blasting Agents (Blasting Sand & Specular Hematite) Subchronic 2016-04-13 TOX-91
Antimony Trioxide Chronic 2016-08-17 TR-590 (2016-02-16)
2,3-Butanedione Chronic 2017-01-18 [1] TR-tbd
Chitosan Subchronic 2016-04-14 TOX-tbd
p-Chloro-a,a,a-trifluorotoluene Subchronic 2016-08-09 TR-594
Hexachlorobenzene Subchronic 2016-04-21 TOX-77
1020 Long Multiwalled Carbon Nanotube (MWNT) Subchronic 2016-06-03 TOX-94
Myristicin Subchronic 2017-01-18 [2] TOX-95
Nanoscale Material (Fullerene C-60) Subchronic 2016-04-13 TOX-87
PCN 66/67 Comparison Study Subchronic 2016-04-18 TOX-90
Ortho-phthalaldehyde Subchronic 2015-11-09 TOX-84
Sodium Tungstate Dihydrate Subchronic 2016-06-03 TOX-tbd
Tetrabromobisphenol A-bis(2,3-dibromopropyl ether) Subchronic 2016-04-18 TOX-tbd
Triethylamine Subchronic 2017-01-18 [3] TOX-78
Tris (chloropropyl) phosphate Subchronic
Zinc Carbonate, Basic Chronic 2016-07-12 TR-592

[1] Revisions to the 2,3-Butanedione Subchronic Study in Rats TDMS Tables: The number of 50 ppm male and female rats with eyes examined microscopically has been updated to 10 for males and 10 for females. No additional diagnoses have been made.
[2] The 3-month mice pathology tables generated before Dec. 9, 2016 have been replaced on the NTP website due to the finding of atrophy of the glandular stomach not present on them.
[3] Revisions to the Triethylamine 14-day and 90-day Tables: Review of the rat and mouse eyes in the 14-day study, and a review of the rat eyes and mouse nasal turbinates in the 90-Day study were conducted to comply with current criteria, concepts, and preferred terminology. As a result, non-neoplastic diagnoses for the eyes of the 14-day rat and mouse studies, the eyes of the 90-day rats, and the nose of the 90-day mice were updated.
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.