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TDMS Study 20114-02 Pathology Tables

NTP  EXP/TEST: 20114-02                         SODIUM DICHROMATE DIHYDRATE (VI)                                  PAGE: 1
TEST TYPE: SUBCHRON 90-DAY                      INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/14/03
ROUTE: DOSED WATER                                                                                                TIME: 14:43:48

                                                         EIS REPORT 03


       FACILITY:  Southern Research Institute

       NTP C#:  C20114

       CONTRACT NUMBER:  N01-ES-15463

       CAS NUMBER:  7789-12-0

       ANIMAL SUPPLIER:  TACONIC FARMS

       CAGE RANGE:  ALL

       DATE RANGE: ALL

       REASONS FOR REMOVAL:    ALL

       REMOVAL DATE RANGE:     ALL

       TREATMENT GROUPS:       INCLUDE ALL

NTP  EXP/TEST: 20114-02                         SODIUM DICHROMATE DIHYDRATE (VI)                                  PAGE: 2
TEST TYPE: SUBCHRON 90-DAY                      INITIAL AND CURRENT BODY WEIGHT                                   DATE: 05/14/03
ROUTE: DOSED WATER                                          EISRPT03                                              TIME: 14:43:48
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 SPECIES-STRAIN: B6C3F1-MICE                SEX: FEMALE      WEEK ON DOSE: 14     FIRST DOSE: 11/14/01
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                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0       MG/L       10     17.9    1.4        10     27.7    2.1                     10      9.8    2.6

 62.5    MG/L       10     18.7    0.9        10     28.0    2.7       101.0         10      9.3    2.3

 125     MG/L       10     18.7    1.1        10     25.5    1.9        92.0         10      6.8    1.2

 250     MG/L       10     18.3    1.2        10     25.5    1.7        92.0         10      7.3    1.4

 500     MG/L       10     18.1    1.1        10     24.8    1.0        89.5         10      6.7    1.1

 1000    MG/L       10     18.8    1.1        10     24.1    1.3        87.0         10      5.3    1.1




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 SPECIES-STRAIN: B6C3F1-MICE                SEX: MALE        WEEK ON DOSE: 14     FIRST DOSE: 11/13/01
----------------------------------------------------------------------------------------------------------------------------------
                     -----INITIAL-----         ------------CURRENT-------------       -----CHANGE------
TREATMENT            N   MEAN(G)    SD         N   MEAN(G)    SD    % REL CNTRL       N   MEAN(G)    SD

 0       MG/L       10     20.4    1.3        10     37.9    3.5                     10     17.5    2.9

 62.5    MG/L       10     21.3    1.2        10     35.6    2.7        93.9         10     14.3    2.3

 125     MG/L       10     21.6    0.8        10     34.2    3.9        90.2         10     12.6    3.6

 250     MG/L       10     21.1    1.8        10     32.6    2.1        86.0         10     11.5    2.2

 500     MG/L       10     20.7    1.7        10     30.5    2.9        80.4         10      9.8    2.5

 1000    MG/L       10     21.4    1.3        10     30.5    1.8        80.4         10      9.1    1.5

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