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TDMS Study 05031-01 Pathology Tables

NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97
Route: GAVAGE                                                                                                     Time: 12:54:12




       Facility:  International Research and Development Corp.

       Chemical CAS #:  7487-94-7

       Lock Date:  None

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All




































Note:  Animals arranged according to CID number

                                                              Page   1

NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 6| 4| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 7| 5|             
                             DAY ON TEST   | 5| 3| 3| 3| 2| 3| 7| 5| 3| 5| 3| 2| 3| 3| 5| 3| 2| 3| 3| 2| 3| 5| 3| 2| 9|             
                                           | 6| 3| 0| 4| 9| 4| 1| 6| 4| 6| 3| 9| 0| 3| 6| 0| 9| 3| 0| 9| 4| 6| 4| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Gallbladder                             |    +  +  +  +  +  M     +     +  +  +  +     +  +  +  +  +  +     +  M  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +  +  +     +     +  M  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  M  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Hemangiosarcoma                      |          X                                                               |             
      Hepatocellular Carcinoma             |                               X                 X                        |             
      Hepatocellular Adenoma               |                         X                                                |             
      Lymphoma Malignant Mixed             |                   X                          X                           |             
                                            __________________________________________________________________________|             
   Mesentery                               |       +                                                                 +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
      Squamous Cell Carcinoma              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                   +                                                     +|             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Pheochromocytoma Benign              |                                                 X                        |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   2                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 6| 4| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 7| 5|             
                             DAY ON TEST   | 5| 3| 3| 3| 2| 3| 7| 5| 3| 5| 3| 2| 3| 3| 5| 3| 2| 3| 3| 2| 3| 5| 3| 2| 9|             
                                           | 6| 3| 0| 4| 9| 4| 1| 6| 4| 6| 3| 9| 0| 3| 6| 0| 9| 3| 0| 9| 4| 6| 4| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +  +  +     +     +  +  +  +     +  +  M  M  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Adenoma                              |                                                                      X   |             
      Lymphoma Malignant Mixed             |                   X                                                      |             
      Pars Intermedia, Adenoma             |                X                                                         |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Mediastinum, Lymphoma Malignant Mixed|                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Adenoma                              |                                              X                           |             
      Granulosa Cell Tumor Benign          |                                                                          |             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
      Endometrium, Polyp Stromal           |                                                                          |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  M  +  M  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                                          |             
      Bronchial, Lymphoma Malignant Mixed  |                                                                          |             
      Iliac, Lymphoma Malignant Mixed      |                   X                                                      |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mandibular, Lymphoma Malignant Mixed |                   X                                                      |             
      Mediastinal, Lymphoma Malignant Mixed|                   X                                                      |             
      Mesenteric, Lymphoma Malignant Mixed |                   X                                                      |             
      Pancreatic, Lymphoma Malignant Mixed |                                              X                           |             
      Renal, Lymphoma Malignant Mixed      |                   X                          X                           |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Hemangiosarcoma                      |          X                                                               |             
      Lymphoma Malignant Mixed             |                   X                          X                           |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  +  M  +  +     +     +  +  +  +     M  +  +  +  M  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  +  +  +  M     +     +  +  +  +     +  +  +  +  M  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   3                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 6| 4| 7| 4| 7| 7| 7| 7| 4| 7| 7| 7| 7| 7| 7| 4| 7| 7| 5|             
                             DAY ON TEST   | 5| 3| 3| 3| 2| 3| 7| 5| 3| 5| 3| 2| 3| 3| 5| 3| 2| 3| 3| 2| 3| 5| 3| 2| 9|             
                                           | 6| 3| 0| 4| 9| 4| 1| 6| 4| 6| 3| 9| 0| 3| 6| 0| 9| 3| 0| 9| 4| 6| 4| 9| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                 +                        |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma       |                                                                          |             
      Lymphoma Malignant Mixed             |                   X                          X                           |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |       +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +  +  +  +  +  +     +     +  +  +  +     +  +  +  +  +  +     +  +  +|             
      Lymphoma Malignant Mixed             |                   X                          X                           |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   4                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 4| 7| 7| 7| 5| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 5| 5| 4| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 5| 5| 3| 3| 3| 3| 2| 3| 5| 3| 2| 3| 2| 2| 1| 3| 6| 6| 5| 3| 3|             
                                           | 0| 4| 3| 0| 6| 6| 3| 3| 0| 5| 9| 0| 6| 0| 9| 3| 9| 9| 7| 0| 0| 5| 6| 3| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  +  +  M        +  +  +  M  +  +     +  +  +  +  I  A  +  M  A     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  A  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +        +  +  +  A  +  +     +  +  +  +  +  A  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  A  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  M  +  +        +  +  +  +  +  +     +  +  +  +  M  A  +  +  M     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  A  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +        +  +  +  A  +  +     +  +  +  +  +  A  +  +  A     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +        +  +  +  A  +  +     +  +  +  +  +  A  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  A  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Hepatocellular Carcinoma             |                                                                          |             
      Hepatocellular Adenoma               |                                                                          |             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
                                            __________________________________________________________________________|             
   Mesentery                               | +                                                     +                  |             
      Lymphoma Malignant Mixed             |                                                       X                  |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  M  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  M  M     +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
      Squamous Cell Carcinoma              |                                                          X               |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                            +                                +  +         |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  M  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   5                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 4| 7| 7| 7| 5| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 5| 5| 4| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 5| 5| 3| 3| 3| 3| 2| 3| 5| 3| 2| 3| 2| 2| 1| 3| 6| 6| 5| 3| 3|             
                                           | 0| 4| 3| 0| 6| 6| 3| 3| 0| 5| 9| 0| 6| 0| 9| 3| 9| 9| 7| 0| 0| 5| 6| 3| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +  M        +  +  +  +  +  +     +  +  +  +  +  +  M  M  +     +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  I  +  +  +     +  +|             
      Adenoma                              |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Pars Intermedia, Adenoma             |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Mediastinum, Lymphoma Malignant Mixed|                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
      Adenoma                              |    X                    X                                            X   |             
      Granulosa Cell Tumor Benign          |                                                    X                     |             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
      Endometrium, Polyp Stromal           |                                                                         X|             
                                            __________________________________________________________________________|             
   Vagina                                  | +  +                 +                                                   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +        M  +  +  +  +  M     +  +  +  +  I  +  +  +  +     +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                       X                  |             
      Bronchial, Lymphoma Malignant Mixed  |                                                                          |             
      Iliac, Lymphoma Malignant Mixed      |       X                                               X     X            |             
      Inguinal, Lymphoma Malignant Mixed   |                                                       X                  |             
      Mandibular, Lymphoma Malignant Mixed |                                                             X            |             
      Mediastinal, Lymphoma Malignant Mixed|       X                                               X     X            |             
      Mesenteric, Lymphoma Malignant Mixed |                                                       X     X            |             
      Pancreatic, Lymphoma Malignant Mixed |       X                                               X     X            |             
      Renal, Lymphoma Malignant Mixed      |    X  X                                               X     X            |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  A  +  +  +     +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant Mixed             |    X  X                 X                                   X            |             
                                            __________________________________________________________________________|             
   Thymus                                  | M  +  +  +        +  +  +  +  +  +     +  +  +  +  M  M  +  +  M     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +        +  +  +  +  +  +     +  +  +  +  I  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   6                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 4| 7| 7| 7| 5| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 5| 5| 4| 7| 7|             
                             DAY ON TEST   | 0| 3| 3| 3| 5| 5| 3| 3| 3| 3| 2| 3| 5| 3| 2| 3| 2| 2| 1| 3| 6| 6| 5| 3| 3|             
                                           | 0| 4| 3| 0| 6| 6| 3| 3| 0| 5| 9| 0| 6| 0| 9| 3| 9| 9| 7| 0| 0| 5| 6| 3| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    CONTROL                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                       +        +         |             
      Lymphoma Malignant Mixed             |                                                       X                  |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Alveolar/Bronchiolar Adenoma         |                         X                                                |             
      Alveolar/Bronchiolar Carcinoma       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  M     +  +|             
      Lymphoma Malignant Mixed             |                                                       X     X            |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |    X  X                 X                             X     X            |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   7                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 2| 7| 7| 4| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 0| 3| 3| 1| 3| 3| 5| 2|                                            |            |
                                           | 4| 9| 5| 4| 4| 1| 3| 4| 6| 9|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |     A      |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  +  A  +  +  A  +  +     M                                             |  38        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +     +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  A  +  +  A  +  +     +                                             |  45        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +     +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  A  +  +  +  +  +     +                                             |  44        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  A  +  +     +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  A  +  +  A  +  +     +                                             |  45        |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  A  +  +     +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  A  +  +     +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +     +                                             |  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatocellular Carcinoma             |                                                                          |          2 |
      Hepatocellular Adenoma               |                                                                          |          1 |
      Lymphoma Malignant Mixed             |       X                                                                  |          5 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |       +  +                                                               |   6        |
      Lymphoma Malignant Mixed             |       X                                                                  |          2 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +     +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +  +     +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +     +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Squamous Cell Carcinoma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  A  +  +  +  +  +     +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |                +                                                         |   6        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +     +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page   8                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 2| 7| 7| 4| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 0| 3| 3| 1| 3| 3| 5| 2|                                            |            |
                                           | 4| 9| 5| 4| 4| 1| 3| 4| 6| 9|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |     A      |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +     +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +     +                                             |  49        |
      Pheochromocytoma Benign              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +     +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  M  M  +  +  M  +  +     +                                             |  40        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +     +                                             |  49        |
      Adenoma                              |          X                                                               |          2 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Pars Intermedia, Adenoma             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |       +                                                                  |   1        |
      Mediastinum, Lymphoma Malignant Mixed|       X                                                                  |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +  +     +                                             |  49        |
      Adenoma                              |                                                                          |          4 |
      Granulosa Cell Tumor Benign          |                                                                          |          1 |
      Lymphoma Malignant Mixed             |       X                                                                  |          4 |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |       X                                                                  |          4 |
      Endometrium, Polyp Stromal           |                            X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Vagina                                  |       +                                                                  |   4        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | M  +  +  +  +  +  +  +     +                                             |  44        |
      Axillary, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Bronchial, Lymphoma Malignant Mixed  |       X                                                                  |          1 |
      Iliac, Lymphoma Malignant Mixed      |                                                                          |          4 |
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Mandibular, Lymphoma Malignant Mixed |       X                                                                  |          3 |
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |          4 |
      Mesenteric, Lymphoma Malignant Mixed |                                                                          |          3 |
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |          4 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page   9                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 2| 7| 7| 4| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 0| 3| 3| 1| 3| 3| 5| 2|                                            |            |
                                           | 4| 9| 5| 4| 4| 1| 3| 4| 6| 9|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |     A      |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Renal, Lymphoma Malignant Mixed      |                                                                          |          6 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +     +                                             |  49        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant Mixed             |       X                                                                  |          7 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | M  +  M  +  +  +  +  +     +                                             |  41        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +     +                                             |  47        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   3        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  |    +                                                                     |   1        |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +     +                                             |  50        |
      Alveolar/Bronchiolar Adenoma         |                   X                                                      |          2 |
      Alveolar/Bronchiolar Carcinoma       |                      X                                                   |          1 |
      Lymphoma Malignant Mixed             |       X                                                                  |          5 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +     +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  10                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 7| 7| 2| 7| 7| 4| 7|                                            |            |
                             DAY ON TEST   | 3| 2| 0| 3| 3| 1| 3| 3| 5| 2|                                            |            |
                                           | 4| 9| 5| 4| 4| 1| 3| 4| 6| 9|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|                                            |     A      |
    CONTROL                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  A  +  +     +                                             |  48        |
      Lymphoma Malignant Mixed             |       X                                                                  |          4 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +     +                                             |  50        |
      Lymphoma Malignant Mixed             |       X     X                                                            |          9 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  11                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 7| 7| 5| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 7| 7| 7| 4| 6| 6| 4| 7| 7|             
                             DAY ON TEST   | 3| 0| 2| 2| 5| 6| 3| 3| 1| 3| 3| 3| 2| 3| 3| 0| 2| 0| 2| 5| 7| 7| 5| 3| 3|             
                                           | 3| 0| 9| 9| 8| 4| 3| 4| 5| 3| 4| 0| 9| 0| 0| 7| 9| 9| 9| 6| 0| 8| 6| 4| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  M  +  +  +  I  +  +  +  +  +  +  +  A  +     +  A     M  +|             
      Lymphoma Malignant Mixed             |                      X                                                   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  M  +  +  +  +  +  +  +  +  +  M  M  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                      X                     |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  A  +  +  +  +  +  +  +  +  +  M  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  A  +  +  A  +  +  +  +  +  +  +  +  +  +  A  +  +  +     +  A     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  A  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                      X                     |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Hemangiosarcoma                      |                                                                X         |             
      Hepatocellular Carcinoma, Multiple   |                                                                          |             
      Lymphoma Malignant Mixed             |             X        X                             X                     |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X        X                                                   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                      X                     |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |             +  +                             M              +  +         |             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M     +  +     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M     +  +     +  +|             
      Pheochromocytoma Benign              |          X                                                               |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Adenoma                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  12                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 7| 7| 5| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 7| 7| 7| 4| 6| 6| 4| 7| 7|             
                             DAY ON TEST   | 3| 0| 2| 2| 5| 6| 3| 3| 1| 3| 3| 3| 2| 3| 3| 0| 2| 0| 2| 5| 7| 7| 5| 3| 3|             
                                           | 3| 0| 9| 9| 8| 4| 3| 4| 5| 3| 4| 0| 9| 0| 0| 7| 9| 9| 9| 6| 0| 8| 6| 4| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M  M  +  +  M  +  +  +  +  +  M  +  +  +  M  +  +  M     +  +     +  M|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  M  +  +  +     +  +     +  +|             
      Adenoma                              |       X                                X                                 |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
      Follicular Cell, Adenoma             |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |    +                                                           +         |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
          Carcinoma, Metastatic, Lung      |    X                                                                     |             
      Mediastinum, Hemangiosarcoma         |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Adenoma                              |                                                                          |             
      Lymphoma Malignant Mixed             |             X        X                             X                     |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Hemangioma                           |                                                                          |             
      Hemangiosarcoma                      |                                                                          |             
      Leiomyosarcoma                       |                            X                                             |             
      Lymphoma Malignant Mixed             |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |                      X                                                   |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     I  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                    X                     |             
      Iliac, Lymphoma Malignant Mixed      |                      X                             X                     |             
      Inguinal, Lymphoma Malignant Mixed   |                      X                                                   |             
      Mandibular, Lymphoma Malignant       |                                                                          |             
          Lymphocytic                      |                                                                         X|             
      Mandibular, Lymphoma Malignant Mixed |             X                                                            |             
      Mediastinal, Lymphoma Malignant Mixed|                      X                             X                     |             
      Mesenteric, Lymphoma Malignant Mixed |             X                                      X                     |             
      Pancreatic, Lymphoma Malignant Mixed |             X        X                             X                     |             
      Renal, Lymphoma Malignant Mixed      |                      X                             X                     |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Hemangiosarcoma                      |                         X                                      X         |             
      Lymphoma Malignant Lymphocytic       |                                                                         X|             
      Lymphoma Malignant Mixed             |             X        X           X                 X                     |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +  +  +  +  I  +  M  +  M  +  +  +  +  +     +  +     M  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  13                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 7| 7| 5| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 7| 7| 7| 4| 6| 6| 4| 7| 7|             
                             DAY ON TEST   | 3| 0| 2| 2| 5| 6| 3| 3| 1| 3| 3| 3| 2| 3| 3| 0| 2| 0| 2| 5| 7| 7| 5| 3| 3|             
                                           | 3| 0| 9| 9| 8| 4| 3| 4| 5| 3| 4| 0| 9| 0| 0| 7| 9| 9| 9| 6| 0| 8| 6| 4| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant Mixed             |             X        X                             X                     |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  M  +  +  +  +  +  +  M  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Fibrosarcoma                         |                                                                      X   |             
      Hemangiosarcoma                      |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |    X                                                                     |             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                      +                                                   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Alveolar/Bronchiolar Adenoma         | X                                               X                        |             
      Alveolar/Bronchiolar Carcinoma       |                               X                                          |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |    X                                                                     |             
      Lymphoma Malignant Mixed             |             X        X                             X                     |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                                            |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |    X                                                                     |             
      Lymphoma Malignant Mixed             |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
      Adenoma                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X        X                             X                     |             
                                            __________________________________________________________________________|             
   Ureter                                  |                                              +                           |             
                                            __________________________________________________________________________|             
   Urethra                                 |    +                                                                     |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +  M     +  +     +  +|             
      Lymphoma Malignant Mixed             |             X                                      X                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  14                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 7| 7| 5| 4| 7| 7| 7| 7| 7| 7| 7| 7| 7| 0| 7| 7| 7| 4| 6| 6| 4| 7| 7|             
                             DAY ON TEST   | 3| 0| 2| 2| 5| 6| 3| 3| 1| 3| 3| 3| 2| 3| 3| 0| 2| 0| 2| 5| 7| 7| 5| 3| 3|             
                                           | 3| 0| 9| 9| 8| 4| 3| 4| 5| 3| 4| 0| 9| 0| 0| 7| 9| 9| 9| 6| 0| 8| 6| 4| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +     +  +     +  +|             
      Lymphoma Malignant Lymphocytic       |                                                                         X|             
      Lymphoma Malignant Mixed             |             X        X           X                 X                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  15                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 4| 6| 4| 4| 7| 7| 4| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 3| 5| 3| 5| 5| 3| 3| 5| 3| 3| 3| 0| 0|             
                                           | 6| 0| 3| 9| 4| 0| 0| 6| 0| 9| 0| 4| 3| 6| 2| 6| 6| 0| 4| 6| 4| 9| 3| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Gallbladder                             |    +  +  +  +  +  +     +  +  +  M  +     +        M  +     +  +  +  +  A|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +  +  +     A  +  +  +  +     +        +  +     +  +  +  +  A|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  A|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Hepatocellular Carcinoma, Multiple   |                               X                                          |             
      Lymphoma Malignant Mixed             |          X                                                           X   |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    M  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                   +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                         +                 +                    +         |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +  +     M  +  +  +  +     +        +  +     +  +  +  +  +|             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Adenoma                              |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  16                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 4| 6| 4| 4| 7| 7| 4| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 3| 5| 3| 5| 5| 3| 3| 5| 3| 3| 3| 0| 0|             
                                           | 6| 0| 3| 9| 4| 0| 0| 6| 0| 9| 0| 4| 3| 6| 2| 6| 6| 0| 4| 6| 4| 9| 3| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +  +  +     M  +  +  +  +     M        +  +     +  M  +  +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Adenoma                              |                   X              X                                       |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
          Carcinoma, Metastatic, Lung      |                                                                          |             
      Mediastinum, Hemangiosarcoma         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |    +  +  +  M  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Adenoma                              |                            X                                             |             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Hemangioma                           |       X                                                                  |             
      Hemangiosarcoma                      |                                                                          |             
      Leiomyosarcoma                       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    M  +  +  +  +  +     +  +  I  +  +     +        I  I     +  +  +  +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                                          |             
      Iliac, Lymphoma Malignant Mixed      |          X                                                           X   |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mandibular, Lymphoma Malignant       |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Mandibular, Lymphoma Malignant Mixed |          X                                                           X   |             
      Mediastinal, Lymphoma Malignant Mixed|          X                                                           X   |             
      Mesenteric, Lymphoma Malignant Mixed |          X                                                               |             
      Pancreatic, Lymphoma Malignant Mixed |          X                                                           X   |             
      Renal, Lymphoma Malignant Mixed      |          X                                                           X   |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |          X              X                                            X   |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  M  M  +  +     +  M  +  M  I     +        +  +     +  +  +  +  M|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  17                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 4| 6| 4| 4| 7| 7| 4| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 3| 5| 3| 5| 5| 3| 3| 5| 3| 3| 3| 0| 0|             
                                           | 6| 0| 3| 9| 4| 0| 0| 6| 0| 9| 0| 4| 3| 6| 2| 6| 6| 0| 4| 6| 4| 9| 3| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                      X   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  M  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Fibrosarcoma                         |                                                       X                 X|             
      Hemangiosarcoma                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                         X                                            X   |             
      Alveolar/Bronchiolar Carcinoma       |                                                                          |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |                                                                          |             
      Lymphoma Malignant Mixed             |          X                                                           X   |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
      Adenoma                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Ureter                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  18                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 7| 7| 4| 6| 7| 7| 7| 7| 4| 6| 4| 4| 7| 7| 4| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 5| 3| 3| 1| 3| 3| 3| 5| 8| 2| 3| 3| 3| 5| 3| 5| 5| 3| 3| 5| 3| 3| 3| 0| 0|             
                                           | 6| 0| 3| 9| 4| 0| 0| 6| 0| 9| 0| 4| 3| 6| 2| 6| 6| 0| 4| 6| 4| 9| 3| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    5MG/KG                                 | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +  +  +  +  +  +     +  +  +  +  +     +        +  +     +  +  +  +  +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |          X              X                                            X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  19                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 4| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 2| 7| 2| 3| 5| 5| 3| 3| 2| 3|                                            |            |
                                           | 9| 3| 9| 3| 6| 6| 3| 3| 9| 0|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |     A      |
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +        +  M  +  +                                             |  41        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +        +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +        +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +        +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | M  +  +  +        +  +  +  +                                             |  46        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +        +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +        +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +        +  +  +  +                                             |  44        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +        +  +  +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +        +  +  +  +                                             |  50        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatocellular Carcinoma, Multiple   |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          6 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                      +                                                   |   1        |
      Lymphoma Malignant Mixed             |                      X                                                   |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +        +  +  +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +        +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +        +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |    +                                                                     |   8        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +        +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +        +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  20                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 4| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 2| 7| 2| 3| 5| 5| 3| 3| 2| 3|                                            |            |
                                           | 9| 3| 9| 3| 6| 6| 3| 3| 9| 0|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |     A      |
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +        +  +  +  +                                             |  48        |
      Pheochromocytoma Benign              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +        +  +  +  +                                             |  50        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +  +        +  +  +  +                                             |  39        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  I  +  +        +  +  +  +                                             |  47        |
      Adenoma                              |                                                                          |          4 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +        +  +  +  +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Follicular Cell, Adenoma             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |                         +                                                |   3        |
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |            |
          Carcinoma, Metastatic, Lung      |                                                                          |          1 |
      Mediastinum, Hemangiosarcoma         |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +        +  +  +  +                                             |  49        |
      Adenoma                              |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          4 |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +        +  +  +  +                                             |  50        |
      Hemangioma                           |                                                                          |          1 |
      Hemangiosarcoma                      |                         X                                                |          1 |
      Leiomyosarcoma                       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | I  +  +  +        +  +  +  +                                             |  44        |
      Axillary, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Iliac, Lymphoma Malignant Mixed      |                                                                          |          4 |
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Mandibular, Lymphoma Malignant       |                                                                          |            |
          Lymphocytic                      |                                                                          |          1 |
      Mandibular, Lymphoma Malignant Mixed |                      X                                                   |          4 |
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |          4 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  21                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 4| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 2| 7| 2| 3| 5| 5| 3| 3| 2| 3|                                            |            |
                                           | 9| 3| 9| 3| 6| 6| 3| 3| 9| 0|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |     A      |
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Mesenteric, Lymphoma Malignant Mixed |                                                                          |          3 |
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |          5 |
      Renal, Lymphoma Malignant Mixed      |                                                                          |          4 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +        +  +  +  +                                             |  50        |
      Hemangiosarcoma                      |                                                                          |          2 |
      Lymphoma Malignant Lymphocytic       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          8 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +        +  +  M  +                                             |  39        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 | X                                                                        |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          5 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +        M  +  +  +                                             |  46        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +        +  +  +  +                                             |  50        |
      Fibrosarcoma                         |    X                                                                     |          4 |
      Hemangiosarcoma                      |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +        +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +        +  +  +  +                                             |  50        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +        +  +  +  +                                             |  50        |
      Alveolar/Bronchiolar Adenoma         |    X                                                                     |          5 |
      Alveolar/Bronchiolar Carcinoma       | X                                                                        |          2 |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Multiple                         |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          5 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +        +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  22                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 7| 7| 4| 4| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 2| 7| 2| 3| 5| 5| 3| 3| 2| 3|                                            |            |
                                           | 9| 3| 9| 3| 6| 6| 3| 3| 9| 0|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|                                            |     A      |
    5MG/KG                                 | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                            +                                             |   1        |
      Adenoma                              |                            X                                             |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                      X                                                   |          4 |
                                            __________________________________________________________________________|____________|
   Ureter                                  |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urethra                                 |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +        +  +  +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +        +  +  +  +                                             |  50        |
      Lymphoma Malignant Lymphocytic       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          8 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  23                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 4| 4| 4| 6| 7| 4| 7| 5| 6| 7| 4| 6| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 5| 2| 5| 2| 5| 5| 5| 8| 3| 5| 3| 6| 7| 2| 5| 6| 3| 3| 3|             
                                           | 0| 3| 0| 7| 0| 4| 6| 9| 1| 9| 6| 6| 6| 8| 0| 6| 3| 2| 2| 9| 6| 9| 4| 0| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | +  +  M  +  +  +     +  A  +           A  M     +  +  +  M     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +     +  A  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +     +  +  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +     +  A  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +     +  A  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +     +  A  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +     +  A  +           A  +     +  +  +  +     A  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Hemangiosarcoma, Metastatic, Spleen  |                                                                          |             
      Hepatocellular Adenoma               |                                                                          |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                        X                                 |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                       +  +               |             
      Lymphoma Malignant Mixed             |                                                          X               |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +     +  +  +           A  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                          X               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Squamous Cell Carcinoma              |                                        X                                 |             
      Squamous Cell Papilloma              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                        X                                 |             
                                            __________________________________________________________________________|             
   Tongue                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                          +               |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |          +              +              +           +  +        +         |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Adenoma                              |                                                                         X|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  24                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 4| 4| 4| 6| 7| 4| 7| 5| 6| 7| 4| 6| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 5| 2| 5| 2| 5| 5| 5| 8| 3| 5| 3| 6| 7| 2| 5| 6| 3| 3| 3|             
                                           | 0| 3| 0| 7| 0| 4| 6| 9| 1| 9| 6| 6| 6| 8| 0| 6| 3| 2| 2| 9| 6| 9| 4| 0| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pheochromocytoma Benign              |                                                                         X|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +     +  +  +           A  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  M  +  M  +  +     +  M  +           M  +     +  +  M  M     M  +  +  M|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  M     M  +  +           M  +     +  +  +  +     +  M  +  +|             
      Adenoma                              |                                                          X               |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                       +                  |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
          Carcinoma, Metastatic, Lung      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Adenoma                              |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Teratoma                             |                                                                          |             
                                            __________________________________________________________________________|             
   Oviduct                                 |                                                          +               |             
      Lymphoma Malignant Mixed             |                                                          X               |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Hemangiosarcoma                      |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
      Cervix, Granular Cell Tumor Benign   |                                                                          |             
      Cervix, Endometrium, Polyp Stromal   |                                           X                              |             
                                            __________________________________________________________________________|             
   Vagina                                  |       +        +     +                                                   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                                          |             
      Iliac, Lymphoma Malignant Mixed      |                                                          X               |             
      Inguinal, Lymphoma Malignant Mixed   |                                                          X               |             
      Mandibular, Lymphoma Malignant Mixed |                                                          X               |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Histiocytic                      |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|                                                          X               |             
      Mesenteric, Lymphoma Malignant Mixed |                                                                          |             
      Mesenteric, Squamous Cell Carcinoma, |                                                                          |             
           Metastatic, Stomach             |                                        X                                 |             
      Pancreatic, Lymphoma Malignant Mixed |                                                          X               |             
      Renal, Lymphoma Malignant Mixed      |                                                          X               |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Hemangioma                           |                                                                X         |             
      Hemangiosarcoma                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  25                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 4| 4| 4| 6| 7| 4| 7| 5| 6| 7| 4| 6| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 5| 2| 5| 2| 5| 5| 5| 8| 3| 5| 3| 6| 7| 2| 5| 6| 3| 3| 3|             
                                           | 0| 3| 0| 7| 0| 4| 6| 9| 1| 9| 6| 6| 6| 8| 0| 6| 3| 2| 2| 9| 6| 9| 4| 0| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  M  +  M     +  +  +           M  +     +  +  +  +     +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +     +  +  +           M  +     +  +  +  +     M  +  +  +|             
      Adenocarcinoma                       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                        +                                 |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Adenocarcinoma, Metastatic,          |                                                                          |             
          Harderian Gland                  |                                           X                              |             
      Alveolar/Bronchiolar Adenoma         |                                           X                              |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                                                                         X|             
      Alveolar/Bronchiolar Carcinoma       |                                                                          |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                        X                                 |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                           +                              |             
      Adenocarcinoma                       |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  26                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 7| 7| 4| 7| 5| 7| 4| 4| 4| 6| 7| 4| 7| 5| 6| 7| 4| 6| 7| 7| 7|             
                             DAY ON TEST   | 3| 3| 3| 3| 3| 3| 5| 2| 5| 2| 5| 5| 5| 8| 3| 5| 3| 6| 7| 2| 5| 6| 3| 3| 3|             
                                           | 0| 3| 0| 7| 0| 4| 6| 9| 1| 9| 6| 6| 6| 8| 0| 6| 3| 2| 2| 9| 6| 9| 4| 0| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +     +  +  +           A  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                          X               |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +     +  +  +           +  +     +  +  +  +     +  +  +  +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                          X               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  27                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 7| 7| 7| 5| 3| 4| 4| 6| 4| 4| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 2| 1| 3| 3| 7| 2| 5| 3| 5| 7| 5| 3| 5| 5| 3| 3| 2| 3| 2| 2| 3| 6| 3| 3| 3|             
                                           | 5| 9| 4| 4| 3| 5| 6| 2| 6| 1| 6| 0| 6| 6| 0| 3| 9| 3| 9| 9| 0| 1| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    10MG/KG                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  +  M  +  +  A     A  A  +     +        +  +  +  +  +  +  +  A  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  +  +  +  +  A     A  A  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | A  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +  +  +  +  A     A  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  +  +  +  +  +     +  A  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  +  +  +  +  A     A  A  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma, Metastatic, Spleen  |                                                                          |             
      Hepatocellular Adenoma               |                         X                    X                           |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |    X                                                                 X   |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                      +   |             
      Lymphoma Malignant Mixed             |                                                                      X   |             
                                            __________________________________________________________________________|             
   Pancreas                                | A  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                      X   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                      X   |             
                                            __________________________________________________________________________|             
   Stomach                                 | A  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | A  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Squamous Cell Carcinoma              |                                                                          |             
      Squamous Cell Papilloma              |                                                             X            |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | A  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |    X                                                                 X   |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  |                                           +                              |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            | +           +  +     +  +  +                                             |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  28                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 7| 7| 7| 5| 3| 4| 4| 6| 4| 4| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 2| 1| 3| 3| 7| 2| 5| 3| 5| 7| 5| 3| 5| 5| 3| 3| 2| 3| 2| 2| 3| 6| 3| 3| 3|             
                                           | 5| 9| 4| 4| 3| 5| 6| 2| 6| 1| 6| 0| 6| 6| 0| 3| 9| 3| 9| 9| 0| 1| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    10MG/KG                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | A  +  +  +  +  +     M  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  M  +  +  M     M  M  M     +        M  +  +  +  M  M  +  M  +  +  M|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                         +                                                |             
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |             
          Carcinoma, Metastatic, Lung      |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Adenoma                              |                                                                          |             
      Lymphoma Malignant Mixed             |    X                                                                     |             
      Teratoma                             |                                                                          |             
                                            __________________________________________________________________________|             
   Oviduct                                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Hemangiosarcoma                      |                                                       X                  |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Cervix, Granular Cell Tumor Benign   |                                           X                              |             
      Cervix, Endometrium, Polyp Stromal   |                                                                          |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                +     +   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  M  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                                      X   |             
      Iliac, Lymphoma Malignant Mixed      |                                                                      X   |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                      X   |             
      Mandibular, Lymphoma Malignant Mixed |                                                                      X   |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Histiocytic                      |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|    X                                                                 X   |             
      Mesenteric, Lymphoma Malignant Mixed |                                                                      X   |             
      Mesenteric, Squamous Cell Carcinoma, |                                                                          |             
           Metastatic, Stomach             |                                                                          |             
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |             
      Renal, Lymphoma Malignant Mixed      |                                                                      X   |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Hemangioma                           |                                                                          |             
      Hemangiosarcoma                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  29                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 7| 7| 7| 5| 3| 4| 4| 6| 4| 4| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 2| 1| 3| 3| 7| 2| 5| 3| 5| 7| 5| 3| 5| 5| 3| 3| 2| 3| 2| 2| 3| 6| 3| 3| 3|             
                                           | 5| 9| 4| 4| 3| 5| 6| 2| 6| 1| 6| 0| 6| 6| 0| 3| 9| 3| 9| 9| 0| 1| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    10MG/KG                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  +  +     M  +  M     +        +  +  +  +  +  +  +  +  +  +  +|             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                         X                                                |             
      Lymphoma Malignant Mixed             |    X                                                                 X   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  M  +  +  +  +|             
      Adenocarcinoma                       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                      X   |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |    +                                                                     |             
      Lymphoma Malignant Mixed             |    X                                                                     |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Adenocarcinoma, Metastatic,          |                                                                          |             
          Harderian Gland                  |                                                                          |             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma       |             X           X                                                |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |    X                                                                 X   |             
      Squamous Cell Carcinoma, Metastatic, |                                                                          |             
           Stomach                         |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
      Adenocarcinoma                       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                      X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  30                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 3| 7| 7| 7| 5| 3| 4| 4| 6| 4| 4| 7| 4| 4| 7| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7|             
                             DAY ON TEST   | 2| 1| 3| 3| 7| 2| 5| 3| 5| 7| 5| 3| 5| 5| 3| 3| 2| 3| 2| 2| 3| 6| 3| 3| 3|             
                                           | 5| 9| 4| 4| 3| 5| 6| 2| 6| 1| 6| 0| 6| 6| 0| 3| 9| 3| 9| 9| 0| 1| 3| 3| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
    10MG/KG                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +     +  +  M     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +     +  +  +     +        +  +  +  +  +  +  +  +  +  +  +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |    X                                                                 X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  31                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 0| 4| 7| 6| 7| 3|                                            |            |
                             DAY ON TEST   | 2| 3| 3| 5| 8| 9| 3| 7| 2| 6|                                            |            |
                                           | 9| 4| 4| 1| 2| 2| 3| 0| 9| 4|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |     A      |
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | M  +  +  +  A  +  I  +  +  A                                             |  35        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  M  +  +  +  +  A                                             |  42        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  M  +  +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  I  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  M  +  +  +  +  A                                             |  45        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  M  +  +  +  +  A                                             |  43        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  M  +  +  +  +  A                                             |  44        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  M  +  +  +  +  A                                             |  41        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hemangiosarcoma, Metastatic, Spleen  |          X                                                               |          1 |
      Hepatocellular Adenoma               |                                                                          |          2 |
      Lymphoma Malignant Histiocytic       |                            X                                             |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
      Squamous Cell Carcinoma, Metastatic, |                                                                          |            |
           Stomach                         |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   3        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  M  +  +  +  +  +                                             |  47        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  M  +  +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  M  +  +  +  +  +                                             |  48        |
      Squamous Cell Carcinoma              |                                                                          |          1 |
      Squamous Cell Papilloma              |          X                                                               |          2 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +     M  +  +  +  +  A                                             |  46        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
      Squamous Cell Carcinoma, Metastatic, |                                                                          |            |
           Stomach                         |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Tongue                                  |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |          +  +  +     +     +                                             |  17        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Histiocytic       |                            X                                             |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  32                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 0| 4| 7| 6| 7| 3|                                            |            |
                             DAY ON TEST   | 2| 3| 3| 5| 8| 9| 3| 7| 2| 6|                                            |            |
                                           | 9| 4| 4| 1| 2| 2| 3| 0| 9| 4|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |     A      |
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  M  +  +  +  +                                             |  49        |
      Pheochromocytoma Benign              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  M  +  +  +  +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  M  M  M  +  +  +  +                                             |  28        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  M  +  +                                             |  45        |
      Adenoma                              |                X                                                         |          2 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  A  +  +  +  +  +                                             |  49        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |          +                                                               |   3        |
      Mediastinum, Alveolar/Bronchiolar    |                                                                          |            |
          Carcinoma, Metastatic, Lung      |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Adenoma                              |                      X                                                   |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Teratoma                             |                      X                                                   |          1 |
                                            __________________________________________________________________________|____________|
   Oviduct                                 |                                                                          |   1        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +  +  A  +  +  +  +  +                                             |  49        |
      Hemangiosarcoma                      |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Cervix, Granular Cell Tumor Benign   |                                                                          |          1 |
      Cervix, Endometrium, Polyp Stromal   |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Vagina                                  |             +     +  +                                                   |   8        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +  M  +  +  +  +                                             |  48        |
      Axillary, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Iliac, Lymphoma Malignant Mixed      |                                                                          |          2 |
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |          2 |
      Mandibular, Lymphoma Malignant Mixed |                                                                          |          2 |
      Mediastinal, Lymphoma Malignant      |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  33                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 0| 4| 7| 6| 7| 3|                                            |            |
                             DAY ON TEST   | 2| 3| 3| 5| 8| 9| 3| 7| 2| 6|                                            |            |
                                           | 9| 4| 4| 1| 2| 2| 3| 0| 9| 4|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |     A      |
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
          Histiocytic                      |                            X                                             |          1 |
      Mediastinal, Lymphoma Malignant Mixed|                      X                                                   |          4 |
      Mesenteric, Lymphoma Malignant Mixed |                      X                                                   |          2 |
      Mesenteric, Squamous Cell Carcinoma, |                                                                          |            |
           Metastatic, Stomach             |                                                                          |          1 |
      Pancreatic, Lymphoma Malignant Mixed |                      X                                                   |          2 |
      Renal, Lymphoma Malignant Mixed      |                      X                                                   |          3 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  M  +  +  +  +  A                                             |  48        |
      Hemangioma                           |                                                                          |          1 |
      Hemangiosarcoma                      |          X                                                               |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          2 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  M  +  +  +  M                                             |  43        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  46        |
      Adenocarcinoma                       | X                                                                        |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   1        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  |                            +                                             |   2        |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Adenocarcinoma, Metastatic,          |                                                                          |            |
          Harderian Gland                  |                                                                          |          1 |
      Alveolar/Bronchiolar Adenoma         |       X                                                                  |          2 |
      Alveolar/Bronchiolar Adenoma,        |                                                                          |            |
          Multiple                         |                                                                          |          1 |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          2 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  34                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 6| 0| 4| 7| 6| 7| 3|                                            |            |
                             DAY ON TEST   | 2| 3| 3| 5| 8| 9| 3| 7| 2| 6|                                            |            |
                                           | 9| 4| 4| 1| 2| 2| 3| 0| 9| 4|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE FEMALE                      | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |     A      |
    10MG/KG                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    FEMALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Histiocytic       |                            X                                             |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          3 |
      Squamous Cell Carcinoma, Metastatic, |                                                                          |            |
           Stomach                         |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                      X                                                   |          1 |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
      Adenocarcinoma                       |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  I  +  +  +  +  +                                             |  47        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Histiocytic       |                            X                                             |          1 |
      Lymphoma Malignant Mixed             |                      X                                                   |          4 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  35                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 0| 4| 7| 7| 5| 0| 7| 4| 7| 7| 1| 7| 7| 7| 7| 4| 7| 7| 4| 4|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 9| 5| 3| 3| 9| 9| 2| 5| 3| 2| 9| 3| 3| 2| 3| 5| 3| 3| 5| 5|             
                                           | 6| 0| 4| 3| 4| 9| 6| 3| 3| 5| 6| 9| 6| 0| 9| 7| 3| 0| 9| 0| 6| 3| 3| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Gallbladder                             |    +  +  +  +  M     +  +  A  +  +     +  M  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  A  +     +  +  +  +  +     +  +  +  +  +  M  +     +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  I      |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  A  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Polyp Adenomatous                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  A  A     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Hemangioma                           |                                                                          |             
      Hepatocellular Carcinoma             |                                                                X         |             
      Hepatocellular Carcinoma, Multiple   |                                                                          |             
      Hepatocellular Adenoma               |                                                                          |             
      Hepatocellular Adenoma, Multiple     |                                  X                                       |             
      Lymphoma Malignant Histiocytic       |             X                                                            |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                  +                                       |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                +           +  +              +                           |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Adenoma                              |                                                                          |             
      Subcapsular, Adenoma                 |                                                    X                     |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +     +  +  M  +  +     +  +  M  +  +  +  +     +  +      |             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  36                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 0| 4| 7| 7| 5| 0| 7| 4| 7| 7| 1| 7| 7| 7| 7| 4| 7| 7| 4| 4|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 9| 5| 3| 3| 9| 9| 2| 5| 3| 2| 9| 3| 3| 2| 3| 5| 3| 3| 5| 5|             
                                           | 6| 0| 4| 3| 4| 9| 6| 3| 3| 5| 6| 9| 6| 0| 9| 7| 3| 0| 9| 0| 6| 3| 3| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  M  +  M     +  +  M  +  M     M  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Adenoma                              |                                                       X                  |             
      Pars Intermedia, Adenoma             |                      X           X                                       |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  M     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Follicular Cell, Carcinoma           |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                            +                                             |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Penis                                   |                +                                                         |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +                             +                             +         |             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +  +     +  +  M  +  +     +  +  +  M  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                +           +  +                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Histiocytic       |             X                                                            |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  M      |             
      Iliac, Lymphoma Malignant Mixed      |                                                                          |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mandibular, Lymphoma Malignant Mixed |                                                                          |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Histiocytic                      |             X                                                            |             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Mesenteric, Lymphoma Malignant       |                                                                          |             
          Histiocytic                      |             X                                                            |             
      Mesenteric, Lymphoma Malignant Mixed |                                                                          |             
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |             
      Renal, Lymphoma Malignant Mixed      |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Histiocytic       |             X                                                            |             
      Lymphoma Malignant Mixed             |                                  X                                       |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  M  +  +     M  +  +  +  M     M  +  +  M  M  +  M     M  +      |             
      Lymphoma Malignant Histiocytic       |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    M  M  M  M  M     M  M  M  M  M     M  M  M  M  M  M  M     M  M      |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Fibrosarcoma                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  37                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 7| 7| 0| 4| 7| 7| 5| 0| 7| 4| 7| 7| 1| 7| 7| 7| 7| 4| 7| 7| 4| 4|             
                             DAY ON TEST   | 5| 3| 3| 3| 3| 9| 5| 3| 3| 9| 9| 2| 5| 3| 2| 9| 3| 3| 2| 3| 5| 3| 3| 5| 5|             
                                           | 6| 0| 4| 3| 4| 9| 6| 3| 3| 5| 6| 9| 6| 0| 9| 7| 3| 0| 9| 0| 6| 3| 3| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                +                                                         |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Alveolar/Bronchiolar Adenoma         |          X                       X                                       |             
      Alveolar/Bronchiolar Carcinoma       |    X                                      X        X                     |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                      +                                                   |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                  +                                       |             
      Adenoma, Multiple                    |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Urethra                                 |                +                                                         |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  M     +  +      |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +  +  +  +  +     +  +  +  +  +     +  +  +  +  +  +  +     +  +      |             
      Lymphoma Malignant Histiocytic       |             X                                                            |             
      Lymphoma Malignant Mixed             |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  38                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 7| 4| 7| 4| 6| 7| 7| 7| 1| 7| 6| 7| 7| 7| 7| 4| 7| 7| 0| 7| 6| 4| 7|             
                             DAY ON TEST   | 6| 0| 3| 5| 2| 5| 3| 2| 3| 2| 2| 3| 9| 2| 3| 3| 3| 5| 2| 3| 8| 3| 9| 5| 3|             
                                           | 2| 5| 4| 7| 9| 6| 7| 9| 0| 9| 9| 4| 9| 9| 4| 3| 4| 6| 9| 0| 5| 3| 5| 6| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | +  +  M  A  +     +  +  +  +  +  +  A  +  +  +  M     +  M  +  +  A     +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  +  +  A  +     +  +  +  +  A  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +     +  +  +  +  +  M  +  +  +  +  +     +  +  +  M  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +     +  M  +  +  +  +  +  M  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | A  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +  +  +  +     +  +  +  +  A  +  +  +  +  +  +     +  +  A  +  +     +|             
      Lymphoma Malignant Mixed             |                         X                                         X      |             
      Polyp Adenomatous                    |                                                                         X|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  +  +  A  +     +  +  +  +  A  +  A  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  A  +  +     +|             
      Lymphoma Malignant Mixed             |                                           X                              |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Hemangioma                           |                                                                   X      |             
      Hepatocellular Carcinoma             |       X                                                                  |             
      Hepatocellular Carcinoma, Multiple   |                                     X           X                        |             
      Hepatocellular Adenoma               |                                  X                                       |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                         X                 X                              |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                     +  +  +                              |             
      Lymphoma Malignant Mixed             |                                           X                              |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Mixed             |                                           X                              |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  M  +  +  +     +|             
                                            __________________________________________________________________________|             
   Tooth                                   |                   +  +                                                   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            | +  +     +                    +                             +            |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Adenoma                              |                                                                          |             
      Subcapsular, Adenoma                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +     +  +  +  +  +  +  +  M  M  +  +     +  +  +  +  +     +|             
      Pheochromocytoma Benign              |          X                                                               |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +     +  +  +  +  +  +  +  +  M  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  39                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 7| 4| 7| 4| 6| 7| 7| 7| 1| 7| 6| 7| 7| 7| 7| 4| 7| 7| 0| 7| 6| 4| 7|             
                             DAY ON TEST   | 6| 0| 3| 5| 2| 5| 3| 2| 3| 2| 2| 3| 9| 2| 3| 3| 3| 5| 2| 3| 8| 3| 9| 5| 3|             
                                           | 2| 5| 4| 7| 9| 6| 7| 9| 0| 9| 9| 4| 9| 9| 4| 3| 4| 6| 9| 0| 5| 3| 5| 6| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +  M  +     M  +  +  +  M  +  M  +  +  +  M     +  M  M  +  M     +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +     +  +  +  +  +  +  +  M  +  +  +     +  M  +  +  +     +|             
      Adenoma                              |                                                                          |             
      Pars Intermedia, Adenoma             |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Follicular Cell, Carcinoma           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                   +      |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Penis                                   | +                       +                                                |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +        +        +     +  +     +                                    |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  M  +  +  +     +|             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |    +     +                                +     +                 +      |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  I  M     +  +  +  +  +  +  +  +  +  +  +     +  +  +  M  +     +|             
      Iliac, Lymphoma Malignant Mixed      |                                           X                              |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mandibular, Lymphoma Malignant Mixed |                                           X                              |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Histiocytic                      |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Mesenteric, Lymphoma Malignant       |                                                                          |             
          Histiocytic                      |                                                                          |             
      Mesenteric, Lymphoma Malignant Mixed |                                           X           X           X      |             
      Pancreatic, Lymphoma Malignant Mixed |                         X                 X                              |             
      Renal, Lymphoma Malignant Mixed      |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                           X           X                  |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  M  M     M  +  M  M  +  +  M  M  M  M  +     M  M  +  +  M     +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  +     M  M  M  M  M  +  M  +  M  M  M     M  M  M  M  M     M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Fibrosarcoma                         |             X                                                           X|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  40                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 7| 4| 7| 4| 6| 7| 7| 7| 1| 7| 6| 7| 7| 7| 7| 4| 7| 7| 0| 7| 6| 4| 7|             
                             DAY ON TEST   | 6| 0| 3| 5| 2| 5| 3| 2| 3| 2| 2| 3| 9| 2| 3| 3| 3| 5| 2| 3| 8| 3| 9| 5| 3|             
                                           | 2| 5| 4| 7| 9| 6| 7| 9| 0| 9| 9| 4| 9| 9| 4| 3| 4| 6| 9| 0| 5| 3| 5| 6| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                        +                                 |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                               +                             +     +      |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Alveolar/Bronchiolar Adenoma         |                      X                                         X         |             
      Alveolar/Bronchiolar Carcinoma       |                                                          X               |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                     X                                    |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
      Adenoma, Multiple                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Mixed             |                                           X                              |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  A  +     I  +  +  +  A  +  +  +  +  +  +     +  +  +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +     +  +  +  +  +     +|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                         X                 X           X           X      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  41                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 7| 7| 7| 7| 7| 7| 4|                                            |            |
                             DAY ON TEST   | 1| 3| 3| 3| 0| 3| 3| 2| 3| 5|                                            |            |
                                           | 2| 0| 4| 4| 1| 0| 4| 9| 3| 6|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  M  +                                                |  49        |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +  +  +  M  +                                                |  40        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +                                                |  45        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +                                                |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +                                                |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  +  +  +  +                                                |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +                                                |  46        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
      Polyp Adenomatous                    |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +                                                |  44        |
      Lymphoma Malignant Mixed             |             X                                                            |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  +                                                |  48        |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +                                                |  50        |
      Hemangioma                           |                                                                          |          1 |
      Hepatocellular Carcinoma             |                                                                          |          2 |
      Hepatocellular Carcinoma, Multiple   |          X                                                               |          3 |
      Hepatocellular Adenoma               |                                                                          |          1 |
      Hepatocellular Adenoma, Multiple     |                                                                          |          1 |
      Lymphoma Malignant Histiocytic       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   3        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +                                                |  50        |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +                                                |  49        |
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   3        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            | +                                                                        |  10        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +                                                |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  42                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 7| 7| 7| 7| 7| 7| 4|                                            |            |
                             DAY ON TEST   | 1| 3| 3| 3| 0| 3| 3| 2| 3| 5|                                            |            |
                                           | 2| 0| 4| 4| 1| 0| 4| 9| 3| 6|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Adenoma                              |                      X                                                   |          1 |
      Subcapsular, Adenoma                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  M  +  +  +  +  +                                                |  45        |
      Pheochromocytoma Benign              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +                                                |  49        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +  +  +  +  +  M                                                |  34        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +                                                |  48        |
      Adenoma                              |                                                                          |          1 |
      Pars Intermedia, Adenoma             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +                                                |  49        |
      Follicular Cell, Carcinoma           |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Coagulating Gland                       |             +                                                            |   3        |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Penis                                   |       +                                                                  |   4        |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |       +     +  +                                                         |  12        |
                                            __________________________________________________________________________|____________|
   Prostate                                | +  I  +  +  +  +  +  +  +                                                |  46        |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |             +                                                            |   9        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +                                                |  50        |
      Lymphoma Malignant Histiocytic       |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  M  +  +  +  +  +  M  +                                                |  44        |
      Iliac, Lymphoma Malignant Mixed      |             X                                                            |          2 |
      Inguinal, Lymphoma Malignant Mixed   |             X                                                            |          1 |
      Mandibular, Lymphoma Malignant Mixed |                                                                          |          1 |
      Mediastinal, Lymphoma Malignant      |                                                                          |            |
          Histiocytic                      |                                                                          |          1 |
      Mediastinal, Lymphoma Malignant Mixed|             X                                                            |          1 |
      Mesenteric, Lymphoma Malignant       |                                                                          |            |
          Histiocytic                      |                                                                          |          1 |
      Mesenteric, Lymphoma Malignant Mixed |       X     X                                                            |          5 |
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |          2 |
      Renal, Lymphoma Malignant Mixed      |             X                                                            |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  43                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 7| 7| 7| 7| 7| 7| 4|                                            |            |
                             DAY ON TEST   | 1| 3| 3| 3| 0| 3| 3| 2| 3| 5|                                            |            |
                                           | 2| 0| 4| 4| 1| 0| 4| 9| 3| 6|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +                                                |  50        |
      Lymphoma Malignant Histiocytic       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |       X     X                                                            |          5 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  M  +  I  +  M  M  +                                                |  26        |
      Lymphoma Malignant Histiocytic       |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  +  M  M  M  M                                                |   4        |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +                                                |  50        |
      Fibrosarcoma                         |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         | +                                                                        |   2        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  | +                                                                        |   5        |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +                                                |  50        |
      Alveolar/Bronchiolar Adenoma         |    X                 X                                                   |          6 |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          4 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |          X                                                               |          2 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +                                                |  50        |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +                                                |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
      Adenoma, Multiple                    |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +                                                |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Urethra                                 |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | M  +  +  +  +  +  +  +  +                                                |  45        |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +                                                |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  44                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 7| 7| 7| 7| 7| 7| 4|                                            |            |
                             DAY ON TEST   | 1| 3| 3| 3| 0| 3| 3| 2| 3| 5|                                            |            |
                                           | 2| 0| 4| 4| 1| 0| 4| 9| 3| 6|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Histiocytic       |                                                                          |          1 |
      Lymphoma Malignant Mixed             |       X     X                                                            |          7 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  45                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 0| 4| 7| 7| 6| 7| 7| 5| 7| 7| 4| 4| 7| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 8| 5| 3| 3| 9| 2| 3| 4| 3| 2| 5| 5| 3| 3| 5|             
                                           | 4| 4| 0| 9| 3| 0| 3| 3| 6| 0| 8| 6| 0| 4| 3| 9| 0| 7| 0| 9| 6| 6| 0| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | M  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  M        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Gallbladder                             | M  M  +  +  +  +  +  M     +  +     +  M  A  +  +  A  M  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +     +  A     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  M  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Adenocarcinoma                       |                                           X                              |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +     +  A     +  +  +  +  +  A  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  A  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +     +  A     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Hemangioma                           |                                                                          |             
      Hepatocellular Carcinoma             | X                                                                        |             
      Hepatocellular Carcinoma, Multiple   |                                                                          |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pharynx                                 |                                              +           +               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | M  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | M  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Squamous Cell Carcinoma              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | M  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                              +                           |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                               +           +        +                     |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  46                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 0| 4| 7| 7| 6| 7| 7| 5| 7| 7| 4| 4| 7| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 8| 5| 3| 3| 9| 2| 3| 4| 3| 2| 5| 5| 3| 3| 5|             
                                           | 4| 4| 0| 9| 3| 0| 3| 3| 6| 0| 8| 6| 0| 4| 3| 9| 0| 7| 0| 9| 6| 6| 0| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M  +  +  +  +  +  +     +  M     M  M  +  +  +  +  +  M        +  +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  M  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | M  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Follicular Cell, Adenoma             |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                       +                  |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                      +                                                   |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Penis                                   |                               +                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         | +           +  +           +  +     +  +     +     +                     |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |          +     +                                +                        |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Axillary, Lymphoma Malignant Mixed   |                                                                          |             
      Iliac, Lymphoma Malignant Mixed      |                                                                          |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Renal, Lymphoma Malignant Mixed      |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | M  +  +  M  +  +  +  M     M  A     +  +  M  +  M  M  M  M        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M  M     M  M     M  M  M  M  M  M  M  M        M  M   |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Fibroma                              |                                                                          |             
      Fibrosarcoma                         |                                                 X                        |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                 +                        |             
      Fibrosarcoma                         |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  47                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 7| 7| 7| 7| 4| 7| 0| 4| 7| 7| 6| 7| 7| 5| 7| 7| 4| 4| 7| 7| 4|             
                             DAY ON TEST   | 3| 3| 3| 2| 3| 3| 3| 3| 5| 3| 8| 5| 3| 3| 9| 2| 3| 4| 3| 2| 5| 5| 3| 3| 5|             
                                           | 4| 4| 0| 9| 3| 0| 3| 3| 6| 0| 8| 6| 0| 4| 3| 9| 0| 7| 0| 9| 6| 6| 0| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Alveolar/Bronchiolar Adenoma         |                X                                      X                  |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                   X                                                      |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                              X                           |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                 +                        |             
      Adenoma                              |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Urethra                                 |                               +                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +     +  +     M  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +  +  +  +        +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  48                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 0| 4| 7| 7| 7| 7| 7| 7| 4| 0| 3| 7| 6| 7| 7| 7| 7| 7| 7| 1| 4| 4| 7| 7|             
                             DAY ON TEST   | 1| 1| 5| 3| 3| 3| 3| 3| 3| 5| 4| 2| 2| 8| 2| 3| 3| 2| 3| 3| 8| 5| 5| 3| 2|             
                                           | 2| 2| 6| 4| 4| 4| 3| 3| 3| 6| 9| 5| 9| 6| 9| 4| 4| 9| 3| 0| 7| 6| 6| 4| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    5MG/KG                                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  A     +  +  +  +  +  +     M  +  +  +  +  +  +  M  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +     +  +  +  +  +  +     M  +  +  A  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  M     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  M     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Adenocarcinoma                       |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         | A  +     +  +  +  +  +  +     +  +  +  A  +  +  +  +  +  +  A  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  +     +  +  +  +  +  +     M  +  +  A  +  +  +  +  +  +  A  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  +     +  +  +  +  +  +     A  +  +  A  +  +  +  +  +  +  A  +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  +     +  +  +  +  +  +     A  +  +  A  +  +  +  +  +  +  A  +     +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Hemangioma                           |                                                                          |             
      Hepatocellular Carcinoma             |                      X                                                   |             
      Hepatocellular Carcinoma, Multiple   |                X                                                         |             
      Hepatocellular Adenoma, Multiple     |             X                                                            |             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  M     +  +  +  +  +  M     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Pharynx                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | M  M     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Squamous Cell Carcinoma              |                                                    X                     |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                +         |             
      Lymphoma Malignant Mixed             |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            | +  +                          +  +     +                    +  +         |             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  M     +  +  +  +  +  M     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  49                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 0| 4| 7| 7| 7| 7| 7| 7| 4| 0| 3| 7| 6| 7| 7| 7| 7| 7| 7| 1| 4| 4| 7| 7|             
                             DAY ON TEST   | 1| 1| 5| 3| 3| 3| 3| 3| 3| 5| 4| 2| 2| 8| 2| 3| 3| 2| 3| 3| 8| 5| 5| 3| 2|             
                                           | 2| 2| 6| 4| 4| 4| 3| 3| 3| 6| 9| 5| 9| 6| 9| 4| 4| 9| 3| 0| 7| 6| 6| 4| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    5MG/KG                                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M     +  +  +  +  +  +     +  +  +  M  +  +  +  M  M  M  +  M     +  M|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | M  +     +  +  I  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | M  +     +  +  +  +  +  +     A  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Penis                                   |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                   +                 +        +                          +|             
                                            __________________________________________________________________________|             
   Prostate                                | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Lymph Node                              | +        +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     I  +|             
      Axillary, Lymphoma Malignant Mixed   |                                        X                       X         |             
      Iliac, Lymphoma Malignant Mixed      |                                        X                       X         |             
      Inguinal, Lymphoma Malignant Mixed   |                                        X                                 |             
      Mediastinal, Lymphoma Malignant Mixed|                                        X                       X         |             
      Renal, Lymphoma Malignant Mixed      |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +     +  +  +  +  +  M     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +     M  +  M  M  +  +     +  +  +  +  +  +  +  +  M  +  +  +     M  +|             
      Lymphoma Malignant Mixed             |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M     M  M  M  M  M  M     M  M  M  M  M  M  M  M  M  M  M  M     M  M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Fibroma                              |                      X                                                   |             
      Fibrosarcoma                         |                                                                          |             
      Lymphoma Malignant Mixed             |                                        X                                 |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Fibrosarcoma                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  50                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 0| 4| 7| 7| 7| 7| 7| 7| 4| 0| 3| 7| 6| 7| 7| 7| 7| 7| 7| 1| 4| 4| 7| 7|             
                             DAY ON TEST   | 1| 1| 5| 3| 3| 3| 3| 3| 3| 5| 4| 2| 2| 8| 2| 3| 3| 2| 3| 3| 8| 5| 5| 3| 2|             
                                           | 2| 2| 6| 4| 4| 4| 3| 3| 3| 6| 9| 5| 9| 6| 9| 4| 4| 9| 3| 0| 7| 6| 6| 4| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    5MG/KG                                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | M  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Alveolar/Bronchiolar Adenoma         |          X     X  X                                                      |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                                     X              X                     |             
      Carcinoma, Metastatic, Uncertain     |                                                                          |             
          Primary Site                     |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                X                                                         |             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                                                X         |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                              +                           |             
      Adenoma                              |                                              X                           |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                                 |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +     +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +  +  +     +  +|             
      Lymphoma Malignant Mixed             |                                        X                       X         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  51                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 2| 6| 4| 7| 4| 5| 7|                                            |            |
                             DAY ON TEST   | 8| 3| 2| 3| 7| 5| 2| 5| 0| 3|                                            |            |
                                           | 7| 0| 9| 0| 3| 6| 9| 6| 9| 3|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |     A      |
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +     +     +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  +  +  +  +     +     A  +                                             |  38        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +     +     +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +     +     +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +     +     +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +     +     +  +                                             |  47        |
      Adenocarcinoma                       |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | A  +  +  +  +     +     +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | A  +  +  +  +     +     +  +                                             |  43        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | A  +  +  +  +     +     A  +                                             |  43        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | A  +  +  +  +     +     A  +                                             |  43        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +     +     +  +                                             |  50        |
      Hemangioma                           |                         X                                                |          1 |
      Hepatocellular Carcinoma             |                                                                          |          2 |
      Hepatocellular Carcinoma, Multiple   |                                                                          |          1 |
      Hepatocellular Adenoma, Multiple     |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +     +  +     +     +  +                                             |  46        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pharynx                                 |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +     +     +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +     +     +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +     +     +  +                                             |  48        |
      Squamous Cell Carcinoma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  I  +  +  +     +     +  +                                             |  47        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   2        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            | +        +  +           +                                                |  14        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +     +     +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +     +     +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  52                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 2| 6| 4| 7| 4| 5| 7|                                            |            |
                             DAY ON TEST   | 8| 3| 2| 3| 7| 5| 2| 5| 0| 3|                                            |            |
                                           | 7| 0| 9| 0| 3| 6| 9| 6| 9| 3|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |     A      |
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +     +     +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +     +     +  +                                             |  50        |
      Pheochromocytoma Benign              |                            X                                             |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +     +     +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +  +     I     +  +                                             |  34        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +     +     +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +     +     +  +                                             |  47        |
      Follicular Cell, Adenoma             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Coagulating Gland                       |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +     +     +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Penis                                   |                         +                                                |   2        |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +                 +                                                |  17        |
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  M  +     +     +  +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |                                                                          |   3        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +     +     +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +     +     +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +     +     +  +                                             |  48        |
      Axillary, Lymphoma Malignant Mixed   |                                                                          |          2 |
      Iliac, Lymphoma Malignant Mixed      |                                                                          |          2 |
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |          2 |
      Renal, Lymphoma Malignant Mixed      |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +     +     +  +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +     M     +  +                                             |  34        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | M  M  M  M  M     M     M  M                                             |            |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +     +     +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  53                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 2| 6| 4| 7| 4| 5| 7|                                            |            |
                             DAY ON TEST   | 8| 3| 2| 3| 7| 5| 2| 5| 0| 3|                                            |            |
                                           | 7| 0| 9| 0| 3| 6| 9| 6| 9| 3|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |     A      |
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Fibroma                              |                                                                          |          1 |
      Fibrosarcoma                         |    X                       X                                             |          3 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +     +     +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |       +                                                                  |   2        |
      Fibrosarcoma                         |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +     +     +  +                                             |  49        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +     +     +  +                                             |  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          5 |
      Alveolar/Bronchiolar Adenoma,        |                                                                          |            |
          Multiple                         |                                                                          |          3 |
      Carcinoma, Metastatic, Uncertain     |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +     +     +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +     +     +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                         +                                                |   3        |
      Adenoma                              |                         X                                                |          3 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +     +     +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Urethra                                 |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | A  +  +  +  +     +     +  +                                             |  48        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +     +     +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  54                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 2| 6| 4| 7| 4| 5| 7|                                            |            |
                             DAY ON TEST   | 8| 3| 2| 3| 7| 5| 2| 5| 0| 3|                                            |            |
                                           | 7| 0| 9| 0| 3| 6| 9| 6| 9| 3|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |     A      |
    5MG/KG                                 | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     L      |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Mixed             |                                                                          |          2 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  55                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 5| 4| 7| 7| 7| 0| 1| 1| 4| 7| 7| 4| 7| 7| 4| 7| 7| 7| 4| 6|             
                             DAY ON TEST   | 3| 3| 2| 0| 7| 5| 5| 3| 3| 3| 0| 2| 3| 5| 2| 3| 5| 3| 3| 5| 3| 2| 3| 7| 4|             
                                           | 3| 0| 9| 4| 1| 1| 6| 0| 0| 4| 6| 9| 8| 6| 9| 4| 6| 3| 0| 6| 3| 8| 0| 1| 2|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | +  +  +  +  +  A     +  +  +  +  +  +     +  +     M  +     +  +  M  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +  A     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  I  +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  A     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  A     +  +  +  +  +  A     +  +     +  +     +  +  +  +  M|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  A     +  +  +  +  +  A     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Hepatocellular Carcinoma             |       X                                      X        X                  |             
      Hepatocellular Adenoma               |                                              X                           |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |          +                                                               |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Hemangioma                           | X                                                                        |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  M  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Squamous Cell Papilloma              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |             +  +              +  +  +                          +     +  +|             
      Vena Cava, Fibrosarcoma, Metastatic, |                                                                          |             
           Skin                            |                                                                X         |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
      Capsule, Lymphoma Malignant Mixed    |                                                                          |             
      Subcapsular, Adenoma                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M  +  +  +  +     +  M  +  M  +  +     +  M     M  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | M  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  M  +  +|             
      Pars Intermedia, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  56                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 5| 4| 7| 7| 7| 0| 1| 1| 4| 7| 7| 4| 7| 7| 4| 7| 7| 7| 4| 6|             
                             DAY ON TEST   | 3| 3| 2| 0| 7| 5| 5| 3| 3| 3| 0| 2| 3| 5| 2| 3| 5| 3| 3| 5| 3| 2| 3| 7| 4|             
                                           | 3| 0| 9| 4| 1| 1| 6| 0| 0| 4| 6| 9| 8| 6| 9| 4| 6| 3| 0| 6| 3| 8| 0| 1| 2|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  I  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                +         |             
      Mediastinum, Fibrosarcoma,           |                                                                          |             
          Metastatic, Skin                 |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Penis                                   |                +                                                         |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +     +  +  I  +  M  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +                                                              +         |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  M  M  +  +|             
      Axillary, Lymphoma Malignant Mixed   |                                                                          |             
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Mesenteric, Lymphoma Malignant Mixed |                                                                          |             
      Pancreatic, Lymphoma Malignant Mixed |                                                                          |             
      Renal, Lymphoma Malignant Mixed      |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                                    M                     |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  | M  +  I  M  M  +     +  +  M  +  +  +     M  +     +  M     M  M  +  M  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M     +  M  M  M  M  M     M  M     M  M     M  M  M  M  M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Fibrosarcoma, Metastatic             |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  57                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 7| 4| 5| 4| 7| 7| 7| 0| 1| 1| 4| 7| 7| 4| 7| 7| 4| 7| 7| 7| 4| 6|             
                             DAY ON TEST   | 3| 3| 2| 0| 7| 5| 5| 3| 3| 3| 0| 2| 3| 5| 2| 3| 5| 3| 3| 5| 3| 2| 3| 7| 4|             
                                           | 3| 0| 9| 4| 1| 1| 6| 0| 0| 4| 6| 9| 8| 6| 9| 4| 6| 3| 0| 6| 3| 8| 0| 1| 2|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  |                               +     +                                +   |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Alveolar/Bronchiolar Adenoma         |                         X                          X                     |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma       | X                                                                        |             
      Fibrosarcoma, Metastatic, Skin       |                                                                X         |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                               +                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         | +                                                                        |             
      Adenoma                              | X                                                                        |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Renal Tubule, Adenocarcinoma         |                                                                          |             
      Renal Tubule, Adenoma                |                                                                         X|             
                                            __________________________________________________________________________|             
   Ureter                                  |                                                                          |             
                                            __________________________________________________________________________|             
   Urethra                                 |          +                          +                                    |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  A     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +     +  +  +  +  +  +     +  +     +  +     +  +  +  +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  58                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 1| 7| 7| 0| 7| 4| 7| 7| 7| 7| 7| 3| 7| 7| 7| 7| 4| 7| 5| 4| 7| 4| 5|             
                             DAY ON TEST   | 3| 3| 7| 3| 3| 0| 3| 5| 3| 3| 3| 3| 3| 0| 3| 2| 2| 2| 5| 3| 5| 5| 3| 5| 4|             
                                           | 1| 6| 3| 4| 3| 9| 3| 6| 0| 4| 4| 4| 3| 9| 0| 9| 9| 9| 6| 4| 5| 6| 4| 6| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Gallbladder                             | A  A  A  +  +  +  +     +  M  +  +  +  A  +  +  +  +     +  A     +     +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  A  M  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Small                         | A  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  A  A  +  +  +  +     +  +  +  +  +  A  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  A  A  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Hepatocellular Carcinoma             |                            X                       X                     |             
      Hepatocellular Adenoma               |                                                                          |             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Mesentery                               |          +                                                               |             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Hemangioma                           |                                                                          |             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Squamous Cell Papilloma              |                                  X                                       |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  M  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Tooth                                   |                                     +                             +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            | +  +  +        +                       +                    +           +|             
      Vena Cava, Fibrosarcoma, Metastatic, |                                                                          |             
           Skin                            |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Lymphoma Malignant Mixed             |          X                                                               |             
      Capsule, Lymphoma Malignant Mixed    |                                                                          |             
      Subcapsular, Adenoma                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  A  M  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M  M  +  +  +  +     +  M  +  +  +  M  M  +  M  +     M  +     M     +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  M  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Pars Intermedia, Adenoma             |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  59                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 1| 7| 7| 0| 7| 4| 7| 7| 7| 7| 7| 3| 7| 7| 7| 7| 4| 7| 5| 4| 7| 4| 5|             
                             DAY ON TEST   | 3| 3| 7| 3| 3| 0| 3| 5| 3| 3| 3| 3| 3| 0| 3| 2| 2| 2| 5| 3| 5| 5| 3| 5| 4|             
                                           | 1| 6| 3| 4| 3| 9| 3| 6| 0| 4| 4| 4| 3| 9| 0| 9| 9| 9| 6| 4| 5| 6| 4| 6| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Mediastinum, Fibrosarcoma,           |                                                                          |             
          Metastatic, Skin                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Penis                                   |       +                 +           +                                   +|             
      Lymphoma Malignant Mixed             |                         X                                                |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                                     +                                   +|             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  I  +        +     +     +|             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +                                                                        |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Lymph Node                              | I  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     M     +|             
      Axillary, Lymphoma Malignant Mixed   |                         X                                                |             
      Inguinal, Lymphoma Malignant Mixed   |                         X                                                |             
      Mediastinal, Lymphoma Malignant Mixed|          X                                                               |             
      Mesenteric, Lymphoma Malignant Mixed |          X                                                               |             
      Pancreatic, Lymphoma Malignant Mixed |          X                                                               |             
      Renal, Lymphoma Malignant Mixed      |          X                                                               |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Lymphoma Malignant Mixed             |          X                                                               |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M  +  M     M  +  M  M  M  +  M  +  M  M     +  I     M     +|             
      Lymphoma Malignant Mixed             |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | M  M  M  M  M  M  M     M  M  M  M  M  M  M  M  M  M     M  M     M     M|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Fibrosarcoma, Metastatic             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  60                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 1| 1| 7| 7| 0| 7| 4| 7| 7| 7| 7| 7| 3| 7| 7| 7| 7| 4| 7| 5| 4| 7| 4| 5|             
                             DAY ON TEST   | 3| 3| 7| 3| 3| 0| 3| 5| 3| 3| 3| 3| 3| 0| 3| 2| 2| 2| 5| 3| 5| 5| 3| 5| 4|             
                                           | 1| 6| 3| 4| 3| 9| 3| 6| 0| 4| 4| 4| 3| 9| 0| 9| 9| 9| 6| 4| 5| 6| 4| 6| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    10MG/KG                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Larynx                                  | +  +                                                                     |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Alveolar/Bronchiolar Adenoma         |                                                    X                     |             
      Alveolar/Bronchiolar Adenoma,        |                                                                          |             
          Multiple                         |                            X                                             |             
      Alveolar/Bronchiolar Carcinoma       |                                     X                                    |             
      Fibrosarcoma, Metastatic, Skin       |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Liver                           |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
      Adenoma                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  A  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Renal Tubule, Adenocarcinoma         |                                                    X                     |             
      Renal Tubule, Adenoma                |                            X                                             |             
                                            __________________________________________________________________________|             
   Ureter                                  |                                              +                           |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  A  +  +  +  +  +     +  +  +  +  +  +  +  I  +  +     +  +     +     +|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +  +     +  +     +     +|             
      Lymphoma Malignant Mixed             |          X              X                                                |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  61                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 4| 4| 7| 0| 7| 7| 7| 5|                                            |            |
                             DAY ON TEST   | 2| 8| 5| 5| 3| 4| 3| 2| 3| 4|                                            |            |
                                           | 9| 7| 6| 6| 3| 8| 0| 9| 3| 8|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     A      |
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |     L      |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +        +  +  +  +  +  I                                             |  49        |
                                            __________________________________________________________________________|____________|
   Gallbladder                             | +  A        +  +  M  +  +  +                                             |  39        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +        +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +        +  +  +  +  +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +        +  +  +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +        +  +  +  +  +  +                                             |  45        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +        +  +  +  +  +  +                                             |  45        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +        +  +  +  +  +  +                                             |  45        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +        +  +  +  +  +  +                                             |  50        |
      Hepatocellular Carcinoma             |                      X                                                   |          6 |
      Hepatocellular Adenoma               |                                                                          |          1 |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   2        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +        +  +  +  +  +  +                                             |  49        |
      Hemangioma                           |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +        +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +        +  +  +  +  +  +                                             |  50        |
      Squamous Cell Papilloma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Tooth                                   |             +                                                            |   3        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |    +           +           +                                             |  18        |
      Vena Cava, Fibrosarcoma, Metastatic, |                                                                          |            |
           Skin                            |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +        +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |             X                                                            |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +        +  +  +  +  +  +                                             |  49        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Capsule, Lymphoma Malignant Mixed    |             X                                                            |          1 |
      Subcapsular, Adenoma                 |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  62                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 4| 4| 7| 0| 7| 7| 7| 5|                                            |            |
                             DAY ON TEST   | 2| 8| 5| 5| 3| 4| 3| 2| 3| 4|                                            |            |
                                           | 9| 7| 6| 6| 3| 8| 0| 9| 3| 8|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     A      |
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |     L      |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +        +  +  +  +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +        +  +  +  +  +  +                                             |  48        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  M        M  M  +  +  +  +                                             |  32        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +        +  +  +  +  +  +                                             |  47        |
      Pars Intermedia, Adenoma             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +        +  +  +  +  +  +                                             |  49        |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |                                                                          |   1        |
      Mediastinum, Fibrosarcoma,           |                                                                          |            |
          Metastatic, Skin                 |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +        +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Penis                                   |             +                                                            |   6        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |                      +                                                   |   3        |
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +        +  +  +  +  +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |                                                                          |   3        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +        +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +        +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | M  +        +  +  +  +  M  +                                             |  43        |
      Axillary, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Inguinal, Lymphoma Malignant Mixed   |                                                                          |          1 |
      Mediastinal, Lymphoma Malignant Mixed|             X                                                            |          2 |
      Mesenteric, Lymphoma Malignant Mixed |             X                                                            |          2 |
      Pancreatic, Lymphoma Malignant Mixed |             X                                                            |          2 |
      Renal, Lymphoma Malignant Mixed      |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +        +  +  +  +  +  +                                             |  49        |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +        +  +  M  M  +  +                                             |  27        |
      Lymphoma Malignant Mixed             |             X                                                            |          2 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | M  M        M  M  M  M  M  +                                             |   2        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  63                                                               
NTP Experiment-Test: 05031-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                         MERCURIC CHLORIDE                                     Date: 04/09/97  
Route: GAVAGE                                                                                                     Time: 12:54:12  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 4| 4| 7| 0| 7| 7| 7| 5|                                            |            |
                             DAY ON TEST   | 2| 8| 5| 5| 3| 4| 3| 2| 3| 4|                                            |            |
                                           | 9| 7| 6| 6| 3| 8| 0| 9| 3| 8|                                            |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     O      |
   B6C3F1 MICE MALE                        | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |     A      |
    10MG/KG                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |     L      |
     MALE                                  | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +        +  +  +  +  +  +                                             |  50        |
      Fibrosarcoma, Metastatic             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +        +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +        +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Larynx                                  |    +                       +                                             |   7        |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +        +  +  +  +  +  +                                             |  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          3 |
      Alveolar/Bronchiolar Adenoma,        |                                                                          |            |
          Multiple                         |                                                                          |          1 |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          2 |
      Fibrosarcoma, Metastatic, Skin       |                                                                          |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Liver                           |                      X                                                   |          1 |
      Lymphoma Malignant Mixed             |             X                                                            |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +        +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +        +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
      Adenoma                              |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +        +  +  +  +  +  +                                             |  49        |
      Renal Tubule, Adenocarcinoma         |                                                                          |          1 |
      Renal Tubule, Adenoma                |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Ureter                                  |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Urethra                                 |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +        +  +  +  +  +  M                                             |  46        |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +        +  +  +  +  +  +                                             |  50        |
      Lymphoma Malignant Mixed             |             X                                                            |          3 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  64                                                               
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