National Toxicology Program

National Toxicology Program
https://ntp.niehs.nih.gov/go/3037

TDMS Study 05033-01 Pathology Tables

NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97
Route: DOSED FEED                                                                                                 Time: 10:08:26




       Facility:  TSI Mason Research

       Chemical CAS #:  117-39-5

       Lock Date:  None

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All




































Note:  Animals arranged according to CID number

                                                              Page   1

NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 1| 7| 7| 1| 6| 6| 7| 7| 7| 7| 6| 7| 6| 6| 4| 4| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 1| 6| 9| 3| 2| 9| 1| 7| 3| 2| 3| 2| 4| 2| 8| 0| 6| 6| 2| 3| 8| 3| 6|             
                                           | 1| 4| 8| 4| 1| 2| 5| 1| 3| 2| 1| 9| 1| 4| 1| 3| 7| 6| 6| 6| 9| 2| 6| 2| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +        +  +     +  +  +  M  +  +  +  +  +  +        +  M  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X        X                             X  X   |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X                                             |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                         +                 +        +                 +   |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +                    +     +  +  +        +  +  +           +         |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X        X                                    |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Glandular, Leukemia Mononuclear      |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X        X                                    |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X        X                                    |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |                            X                                             |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |       +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Adenoma                              |                                     X           X                        |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +        +  +     +  +  +  +  +  +  +  M  +  +        M  M  +  M   |             
      Adenoma                              |                               X                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Pars Distalis, Adenoma               | X  X  X        X        X  X  X  X     X  X  X  X           X  X  X  X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   2                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 1| 7| 7| 1| 6| 6| 7| 7| 7| 7| 6| 7| 6| 6| 4| 4| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 1| 6| 9| 3| 2| 9| 1| 7| 3| 2| 3| 2| 4| 2| 8| 0| 6| 6| 2| 3| 8| 3| 6|             
                                           | 1| 4| 8| 4| 1| 2| 5| 1| 3| 2| 1| 9| 1| 4| 1| 3| 7| 6| 6| 6| 9| 2| 6| 2| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                            X                                             |             
      Pars Distalis, Pars Intermedia, Pars |                                                                          |             
          Nervosa, Leukemia Mononuclear    |                                                                          |             
      Pars Intermedia, Leukemia Mononuclear|                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      C-Cell, Adenoma                      | X                                                                        |             
      C-Cell, Carcinoma                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |                   +              +  +     +        +                 +   |             
      Adenoma                              |                                  X  X                                    |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Granulosa Cell Tumor Benign          |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leiomyoma                            |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
      Polyp Stromal                        | X                             X                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                         +                 +        +                 +   |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                            X                                             |             
      Renal, Leukemia Mononuclear          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  M   |             
      Leukemia Mononuclear                 |                            X                                      X      |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                         +                 +        +                 +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Hemangioma                           |                                                                          |             
      Leukemia Mononuclear                 |                            X        X                             X  X   |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +                    +                 +        +                 M   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +     +        +        +  +        +  +  +  +  +  +        +  +  +  +   |             
      Adenocarcinoma                       |                            X                                             |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   3                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 1| 7| 7| 1| 6| 6| 7| 7| 7| 7| 6| 7| 6| 6| 4| 4| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 1| 6| 9| 3| 2| 9| 1| 7| 3| 2| 3| 2| 4| 2| 8| 0| 6| 6| 2| 3| 8| 3| 6|             
                                           | 1| 4| 8| 4| 1| 2| 5| 1| 3| 2| 1| 9| 1| 4| 1| 3| 7| 6| 6| 6| 9| 2| 6| 2| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Fibroadenoma                         |                         X           X        X  X  X        X            |             
      Fibroadenoma, Multiple               | X     X        X                                               X  X      |             
                                            __________________________________________________________________________|             
   Skin                                    |       +                 +                 +  +     +                 +   |             
      Subcutaneous Tissue, Carcinosarcoma, |                                                                          |             
           Poorly Differentiated           |                                           X                              |             
      Subcutaneous Tissue, Fibroma         |       X                                                                  |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                         +                 +        +                 +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                           +                              |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Alveolar/Bronchiolar Adenoma         |                            X  X        X  X                              |             
      Carcinosarcoma, Metastatic, Skin     |                                           X                              |             
      Leukemia Mononuclear                 |                            X        X                             X  X   |             
      Mediastinum, Leukemia Mononuclear    |                                                                          |             
      Parenchyma, Leukemia Mononuclear     |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |                         +                 +                          +   |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
      Fibrosarcoma                         |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +                                   +                             +   |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                                                                          |             
      Adenoma                              |                                                                          |             
      Squamous Cell Carcinoma              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  A  +   |             
      Leukemia Mononuclear                 |                                     X                                    |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Papilloma                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +        +  +     +  +  +  +  +  +  +  +  +  +        +  +  +  +   |             
      Leukemia Mononuclear                 |                            X        X                             X  X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   4                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 4| 1| 7| 7| 6| 1| 4| 7| 6| 1| 4| 4| 7| 7| 6| 7| 1| 7| 7| 7| 7| 4|             
                             DAY ON TEST   | 2| 3| 9| 6| 9| 3| 3| 7| 9| 6| 2| 2| 9| 6| 2| 3| 2| 6| 2| 9| 2| 3| 2| 2| 6|             
                                           | 8| 2| 1| 4| 1| 1| 2| 2| 1| 4| 4| 5| 3| 6| 2| 1| 9| 0| 4| 3| 9| 2| 5| 4| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +           +  +  +        +  +        M  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 | X                                         X  X                           |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                           +  +                           |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                  +        M                              |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +              +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +           +                          M  +  +     +     +  +  +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 | X                                                                        |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Glandular, Leukemia Mononuclear      |                                           X                              |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +           +  +  +        +  +           +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Pheochromocytoma Malignant           |                                                                   X      |             
      Pheochromocytoma Benign              |                                  X                                X      |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  M           +  +  +        M  M        +  +  +  +  +     +  +  +  I   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Pars Distalis, Adenoma               | X                 X  X                       X  X  X  X     X  X     X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   5                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 4| 1| 7| 7| 6| 1| 4| 7| 6| 1| 4| 4| 7| 7| 6| 7| 1| 7| 7| 7| 7| 4|             
                             DAY ON TEST   | 2| 3| 9| 6| 9| 3| 3| 7| 9| 6| 2| 2| 9| 6| 2| 3| 2| 6| 2| 9| 2| 3| 2| 2| 6|             
                                           | 8| 2| 1| 4| 1| 1| 2| 2| 1| 4| 4| 5| 3| 6| 2| 1| 9| 0| 4| 3| 9| 2| 5| 4| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                                           X                              |             
      Pars Distalis, Pars Intermedia, Pars |                                                                          |             
          Nervosa, Leukemia Mononuclear    |                                              X                           |             
      Pars Intermedia, Leukemia Mononuclear|                                           X                              |             
      Pars Nervosa, Leukemia Mononuclear   |                                           X                              |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      C-Cell, Adenoma                      |                   X                                   X           X  X   |             
      C-Cell, Carcinoma                    |    X                                                                     |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +                             M           +           +                  |             
      Adenoma                              | X                                                     X                  |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Granulosa Cell Tumor Benign          |                                                                          |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leiomyoma                            |                                                                      X   |             
      Leukemia Mononuclear                 |                                           X                              |             
      Polyp Stromal                        |                               X  X                                       |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                  +        +                              |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +           +  M  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Mediastinal, Leukemia Mononuclear    |                                           X                              |             
      Pancreatic, Leukemia Mononuclear     | X                                         X  X                           |             
      Renal, Leukemia Mononuclear          | X                                                                        |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +           +  M  +        +  +        M  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                              X                           |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                  +        +                              |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Hemangioma                           |                                           X                              |             
      Leukemia Mononuclear                 | X                                         X  X                           |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                  +        +                              |             
      Leukemia Mononuclear                 |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +           +     +        +  +        +     +  +        +  +         |             
      Adenocarcinoma                       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   6                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 4| 1| 7| 7| 6| 1| 4| 7| 6| 1| 4| 4| 7| 7| 6| 7| 1| 7| 7| 7| 7| 4|             
                             DAY ON TEST   | 2| 3| 9| 6| 9| 3| 3| 7| 9| 6| 2| 2| 9| 6| 2| 3| 2| 6| 2| 9| 2| 3| 2| 2| 6|             
                                           | 8| 2| 1| 4| 1| 1| 2| 2| 1| 4| 4| 5| 3| 6| 2| 1| 9| 0| 4| 3| 9| 2| 5| 4| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6|             
    CONTROL                                | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|             
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Fibroadenoma                         | X  X           X     X        X  X              X  X        X  X         |             
      Fibroadenoma, Multiple               |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                   +              +        +                              |             
      Subcutaneous Tissue, Carcinosarcoma, |                                                                          |             
           Poorly Differentiated           |                                                                          |             
      Subcutaneous Tissue, Fibroma         |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                  +        +                              |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Alveolar/Bronchiolar Adenoma         |    X                                                                     |             
      Carcinosarcoma, Metastatic, Skin     |                                                                          |             
      Leukemia Mononuclear                 | X                                         X  X                           |             
      Mediastinum, Leukemia Mononuclear    |                                           X                              |             
      Parenchyma, Leukemia Mononuclear     |                                           X                              |             
                                            __________________________________________________________________________|             
   Nose                                    |                                  +        +                              |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +           +  +  +        +           +  +  +  +  +     +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
      Fibrosarcoma                         |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                      +   |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                                                                          |             
      Adenoma                              |                                                                          |             
      Squamous Cell Carcinoma              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 | X                                         X                              |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 | X                                         X                              |             
      Papilloma                            |                X                                                         |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +           +  +  +        +  +        +  +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 | X                                         X  X                           |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   7                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 1| 4| 7| 7| 6| 1| 1| 7| 7| 7| 6| 5| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 2| 1| 8| 9| 6| 3| 0| 6| 9| 9| 2| 1| 0| 1| 9| 3| 2| 2| 2| 6|              |            |
                                           | 3| 8| 7| 3| 4| 1| 0| 0| 3| 3| 4| 8| 0| 9| 7| 1| 9| 3| 3| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|              |     A      |
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|              |     L      |
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |       X                          X                                       |          9 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   2        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |                                        +  +                              |   7        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  49        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +  +           +              +  +        +  +  +  +  +                  |  29        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Glandular, Leukemia Mononuclear      |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  49        |
      Leukemia Mononuclear                 |       X                                                                  |          3 |
      Pheochromocytoma Malignant           |                                                                          |          1 |
      Pheochromocytoma Benign              |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +        +                 +     +  +  +  +  +  +                  |  44        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page   8                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 1| 4| 7| 7| 6| 1| 1| 7| 7| 7| 6| 5| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 2| 1| 8| 9| 6| 3| 0| 6| 9| 9| 2| 1| 0| 1| 9| 3| 2| 2| 2| 6|              |            |
                                           | 3| 8| 7| 3| 4| 1| 0| 0| 3| 3| 4| 8| 0| 9| 7| 1| 9| 3| 3| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|              |     A      |
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|              |     L      |
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Adenoma                              |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +        +  +  +        +  +  +  +  +  +  +  +  M                  |  40        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Pars Distalis, Adenoma               | X  X              X           X  X        X                              |         32 |
      Pars Distalis, Adenoma, Multiple     |                      X              X  X     X     X                     |          5 |
      Pars Distalis, Leukemia Mononuclear  |       X                          X                                       |          4 |
      Pars Distalis, Pars Intermedia, Pars |                                                                          |            |
          Nervosa, Leukemia Mononuclear    |                                                                          |          1 |
      Pars Intermedia, Leukemia Mononuclear|                                                                          |          1 |
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      C-Cell, Adenoma                      |                               X                                          |          6 |
      C-Cell, Carcinoma                    |                      X                                                   |          2 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          |       +           +                 +  +  +                              |  14        |
      Adenoma                              |                                                                          |          4 |
      Carcinoma                            |                                     X                                    |          1 |
                                            __________________________________________________________________________|____________|
   Ovary                                   | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Granulosa Cell Tumor Benign          |       X                                                                  |          1 |
      Leukemia Mononuclear                 |                                  X                                       |          2 |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leiomyoma                            |                                                                          |          1 |
      Leukemia Mononuclear                 |                                                                          |          1 |
      Polyp Stromal                        |                                        X  X           X                  |          7 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |                                        +  +                              |   8        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +        +  +  +        +  +  +  +  +  +  +  M  +                  |  48        |
      Mediastinal, Leukemia Mononuclear    |                                  X                                       |          2 |
      Pancreatic, Leukemia Mononuclear     |                                  X                                       |          5 |
      Renal, Leukemia Mononuclear          |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  +        +  +  +        +  +  +  +  +  +  +  M  +                  |  46        |
      Leukemia Mononuclear                 |       X                          X                                       |          5 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |       +                                +  +                              |   9        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page   9                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 1| 4| 7| 7| 6| 1| 1| 7| 7| 7| 6| 5| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 2| 1| 8| 9| 6| 3| 0| 6| 9| 9| 2| 1| 0| 1| 9| 3| 2| 2| 2| 6|              |            |
                                           | 3| 8| 7| 3| 4| 1| 0| 0| 3| 3| 4| 8| 0| 9| 7| 1| 9| 3| 3| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|              |     A      |
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|              |     L      |
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Hemangioma                           |                                                                          |          1 |
      Leukemia Mononuclear                 |       X                          X                                       |          9 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |                                        +  +                              |   8        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +              +  +  +           +     +  +     +  +  +                  |  36        |
      Adenocarcinoma                       |                                                                          |          1 |
      Fibroadenoma                         |                X  X  X                    X     X                        |         21 |
      Fibroadenoma, Multiple               |                                  X     X              X                  |          8 |
                                            __________________________________________________________________________|____________|
   Skin                                    |                                        +  +                              |  11        |
      Subcutaneous Tissue, Carcinosarcoma, |                                                                          |            |
           Poorly Differentiated           |                                                                          |          1 |
      Subcutaneous Tissue, Fibroma         |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |                                        +  +                              |   8        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          5 |
      Carcinosarcoma, Metastatic, Skin     |                                                                          |          1 |
      Leukemia Mononuclear                 |       X                          X                                       |          9 |
      Mediastinum, Leukemia Mononuclear    |                                                                          |          1 |
      Parenchyma, Leukemia Mononuclear     |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    |                                        +  +                              |   7        |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  49        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                 +                        |   1        |
      Fibrosarcoma                         |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Eye                                     |    +                                            +                        |   6        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  10                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 1| 4| 7| 7| 6| 1| 1| 7| 7| 7| 6| 5| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 2| 1| 8| 9| 6| 3| 0| 6| 9| 9| 2| 1| 0| 1| 9| 3| 2| 2| 2| 6|              |            |
                                           | 3| 8| 7| 3| 4| 1| 0| 0| 3| 3| 4| 8| 0| 9| 7| 1| 9| 3| 3| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|              |     A      |
    CONTROL                                | 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|              |     L      |
    UF                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 SPECIAL SENSES SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Zymbal's Gland                          |                      +                          +                        |   2        |
      Adenoma                              |                                                 X                        |          1 |
      Squamous Cell Carcinoma              |                      X                                                   |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  49        |
      Leukemia Mononuclear                 |       X                          X                                       |          5 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Papilloma                            |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +        +  +  +        +  +  +  +  +  +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |       X                          X                                       |          9 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  11                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 6| 6| 7| 6| 6| 4| 5| 7| 6| 6| 6| 5| 7| 7| 4| 1| 4| 7| 7| 7| 6| 4|             
                             DAY ON TEST   | 2| 6| 2| 8| 1| 0| 0| 0| 6| 9| 2| 8| 2| 1| 1| 2| 2| 6| 9| 6| 2| 2| 2| 4| 6|             
                                           | 9| 8| 5| 0| 3| 4| 3| 3| 4| 7| 3| 0| 6| 2| 5| 8| 5| 4| 1| 4| 9| 9| 3| 5| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Intestine Large                         |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leiomyoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                X                 X        X                    X         |             
      Neoplastic Nodule                    |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |          M                    +                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                                  X                                       |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +  +     M  +  +     +  +  +        +  +  +           +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |             +     +  +     +        +  +  +                              |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
      Leukemia Mononuclear                 |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +        +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |             +     +  +     +        +  +  +                              |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |             +     +  +     +        +  +  +                              |             
      Leukemia Mononuclear                 |                                                                          |             
      Pheochromocytoma Malignant           |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +           +     +  +     +        +  +  +                              |             
      Adenoma                              | X                                                                        |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  M  +  +  +  +     +  +  M  +  +  +  M  +           +  M  +  +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Pars Distalis, Adenoma               | X  X  X  X  X  X  X  X              X        X              X  X     X   |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
      Pars Distalis, Carcinoma             |                                        X                                 |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  12                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 6| 6| 7| 6| 6| 4| 5| 7| 6| 6| 6| 5| 7| 7| 4| 1| 4| 7| 7| 7| 6| 4|             
                             DAY ON TEST   | 2| 6| 2| 8| 1| 0| 0| 0| 6| 9| 2| 8| 2| 1| 1| 2| 2| 6| 9| 6| 2| 2| 2| 4| 6|             
                                           | 9| 8| 5| 0| 3| 4| 3| 3| 4| 7| 3| 0| 6| 2| 5| 8| 5| 4| 1| 4| 9| 9| 3| 5| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +     +  +     +  +  +  +  +           +  +  +  +   |             
      C-Cell, Adenoma                      |       X                                      X                           |             
      C-Cell, Carcinoma                    |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |             +     +  +     +           +  +                 +            |             
      Adenoma                              |                                                                          |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   |             +     +  +     +        +  +  +                              |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Polyp Stromal                        |       X                                   X                    X         |             
      Polyp Stromal, Multiple              |                                                                      X   |             
      Sarcoma Stromal                      |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood                                   |    +                                                                     |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Lymph Node                              |          +  +  +  +  +     +     +  +  +  +                              |             
      Lumbar, Leukemia Mononuclear         |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                                          |             
      Renal, Leukemia Mononuclear          |                                  X                                       |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |             +  +  +  +     +        +  +  +                              |             
      Leukemia Mononuclear                 |                                           X                              |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |             +     +  +     +     +  +  +  +                              |             
      Leukemia Mononuclear                 |                                  X        X                              |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +     +  +  +  +  +     +     +  +  +  +  +                    +      |             
      Leukemia Mononuclear                 |                X                 X        X                              |             
                                            __________________________________________________________________________|             
   Thymus                                  |             M     +  +     +     +  +  M  +                              |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +     +  +     +  +     +        +  +  +  +              +  +         |             
      Fibroadenoma                         |    X     X                 X        X  X                                 |             
      Fibroadenoma, Multiple               |                                              X              X  X         |             
                                            __________________________________________________________________________|             
   Skin                                    |                +  +  +     +     +  +  +  +     +                        |             
      Subcutaneous Tissue, Fibroma         |                X                                X                        |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  13                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 7| 6| 6| 7| 6| 6| 4| 5| 7| 6| 6| 6| 5| 7| 7| 4| 1| 4| 7| 7| 7| 6| 4|             
                             DAY ON TEST   | 2| 6| 2| 8| 1| 0| 0| 0| 6| 9| 2| 8| 2| 1| 1| 2| 2| 6| 9| 6| 2| 2| 2| 4| 6|             
                                           | 9| 8| 5| 0| 3| 4| 3| 3| 4| 7| 3| 0| 6| 2| 5| 8| 5| 4| 1| 4| 9| 9| 3| 5| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7|             
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +        +     +  +     +        +  +  +                              |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |             +     +  +     +     +  +  +  +                              |             
      Leukemia Mononuclear                 |                                  X                                       |             
      Medulla, Carcinoma, Metastatic,      |                                                                          |             
          Pituitary Gland                  |                                        X                                 |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |          +  +  +  +  +     +        +  +  +                       +      |             
      Alveolar/Bronchiolar Carcinoma       |                                                                          |             
      Leukemia Mononuclear                 |                                           X                              |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic                       |                                                                          |             
      Sarcoma, Metastatic, Lung            |                                                                          |             
      Pleura, Alveolar/Bronchiolar         |                                                                          |             
          Carcinoma, Metastatic, Lung      |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |             +     +  +     +        +  +  +                              |             
                                            __________________________________________________________________________|             
   Trachea                                 |             +     +  +     +        +  +  +                              |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |       +     I  I                                I           +            |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |             +                                               +            |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                +                                                         |             
      Squamous Cell Carcinoma              |                X                                                         |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +     +  +  +     +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +           +  +  +  +   |             
      Leukemia Mononuclear                 |                X                 X        X                    X         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  14                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 1| 7| 4| 7| 7| 7| 6| 4| 7| 7| 1| 6| 5| 7| 7| 7| 7| 4| 1| 7| 5| 4| 1|             
                             DAY ON TEST   | 9| 2| 9| 2| 9| 2| 2| 2| 8| 6| 3| 2| 9| 8| 4| 2| 2| 3| 2| 6| 9| 2| 4| 6| 9|             
                                           | 1| 3| 1| 5| 7| 3| 3| 9| 3| 4| 1| 4| 1| 7| 3| 3| 3| 1| 4| 6| 1| 1| 8| 6| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
    0.1% LF                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Intestine Large                         |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leiomyoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +     +  +  +  +  +  +     +  +     +  M  +  +  +  +        +  +      |             
                                            __________________________________________________________________________|             
   Liver                                   |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                        X        X  X                     |             
      Neoplastic Nodule                    |                                                    X                     |             
                                            __________________________________________________________________________|             
   Mesentery                               |          +                                      +     +                  |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  |    +     +  +  +  +  +  M     +  +     M  +  +  +  +  +        +  +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |             +  +                          +                       +      |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                   X      |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |             +                             +                       +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |             +                             +                       +      |             
      Leukemia Mononuclear                 |                                                                          |             
      Pheochromocytoma Malignant           |             X                                                            |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |             +                             +           +           +      |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +     M  +  +  +  +  M     M  +     +  M  +  +  +  +        +  +      |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Pars Distalis, Adenoma               |    X        X  X     X                       X     X  X           X      |             
      Pars Distalis, Adenoma, Multiple     |                                        X                                 |             
      Pars Distalis, Carcinoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  15                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 1| 7| 4| 7| 7| 7| 6| 4| 7| 7| 1| 6| 5| 7| 7| 7| 7| 4| 1| 7| 5| 4| 1|             
                             DAY ON TEST   | 9| 2| 9| 2| 9| 2| 2| 2| 8| 6| 3| 2| 9| 8| 4| 2| 2| 3| 2| 6| 9| 2| 4| 6| 9|             
                                           | 1| 3| 1| 5| 7| 3| 3| 9| 3| 4| 1| 4| 1| 7| 3| 3| 3| 1| 4| 6| 1| 1| 8| 6| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
    0.1% LF                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                                                 X                        |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +        +  +  +  +  +     +        +  +     +  +              +      |             
      C-Cell, Adenoma                      |                X                                                         |             
      C-Cell, Carcinoma                    |                      X                                                   |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |             +     +              +        +                    +  +      |             
      Adenoma                              |                   X                                            X         |             
      Carcinoma                            |                                  X                                       |             
                                            __________________________________________________________________________|             
   Ovary                                   |             +           +                 +     +     +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Polyp Stromal                        |                X  X                                            X         |             
      Polyp Stromal, Multiple              |                                                                          |             
      Sarcoma Stromal                      |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood                                   |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Lymph Node                              |          +  +  +        +              +  +     +  +              +      |             
      Lumbar, Leukemia Mononuclear         |                                                    X                     |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                    X                     |             
      Renal, Leukemia Mononuclear          |                                                 X                        |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |          +  +           +              +  +                       +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |             +                             +                       +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |             +     +              +        +     +  +              +      |             
      Leukemia Mononuclear                 |                                                 X  X                     |             
                                            __________________________________________________________________________|             
   Thymus                                  |             +                             +                       +      |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Metastatic, Lung                 |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +     +  +  +  +     +     +        +  +  +  +  +           +  +      |             
      Fibroadenoma                         |    X     X        X     X     X        X     X     X           X         |             
      Fibroadenoma, Multiple               |                X                                X                        |             
                                            __________________________________________________________________________|             
   Skin                                    |             +                             +  +                    +      |             
      Subcutaneous Tissue, Fibroma         |                                              X                           |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  16                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 1| 7| 4| 7| 7| 7| 6| 4| 7| 7| 1| 6| 5| 7| 7| 7| 7| 4| 1| 7| 5| 4| 1|             
                             DAY ON TEST   | 9| 2| 9| 2| 9| 2| 2| 2| 8| 6| 3| 2| 9| 8| 4| 2| 2| 3| 2| 6| 9| 2| 4| 6| 9|             
                                           | 1| 3| 1| 5| 7| 3| 3| 9| 3| 4| 1| 4| 1| 7| 3| 3| 3| 1| 4| 6| 1| 1| 8| 6| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
    0.1% LF                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |             +                             +                       +      |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |             +                             +        +              +      |             
      Leukemia Mononuclear                 |                                                    X                     |             
      Medulla, Carcinoma, Metastatic,      |                                                                          |             
          Pituitary Gland                  |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                    +                     |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |             +           +              +  +                       +      |             
      Alveolar/Bronchiolar Carcinoma       |                                                                   X      |             
      Leukemia Mononuclear                 |                                                                          |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic                       |             X                                                            |             
      Sarcoma, Metastatic, Lung            |                                                                          |             
      Pleura, Alveolar/Bronchiolar         |                                                                          |             
          Carcinoma, Metastatic, Lung      |                                                                   X      |             
                                            __________________________________________________________________________|             
   Nose                                    |             +                             +                       +      |             
                                            __________________________________________________________________________|             
   Trachea                                 |             +                             +                       +      |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                    +                     |             
                                            __________________________________________________________________________|             
   Eye                                     |          +           +  +                          +           I         |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |          +                                                               |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                         +                                                |             
      Squamous Cell Carcinoma              |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +     +  +  +  +  +  +     +  +     +  +  +  +  +  +        +  +      |             
      Leukemia Mononuclear                 |                                        X        X  X                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  17                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 1| 5| 4| 7| 7| 1| 7| 6| 7| 7| 6| 5| 4| 7| 1| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 9| 9| 9| 6| 3| 3| 9| 2| 9| 2| 2| 7| 0| 6| 2| 9| 2| 2| 6|              |            |
                                           | 1| 3| 3| 6| 4| 1| 1| 3| 5| 6| 5| 5| 6| 4| 4| 3| 3| 5| 5| 6|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|              |     A      |
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |          +                             +                                 |  12        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |          +                             A                                 |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |          +                             A                                 |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |          +                             A                                 |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |          +                             A                                 |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +        +     +  +     +  +  +  +  +  A     +     +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +        +     +  +     +  +  +  +  A  A     +     +  +                  |  48        |
      Leiomyoma                            |                                                       X                  |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +        +     +  +     +  +  +  +  A  A     +     +  +                  |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +        +     +  +     +  +  +  +  A  A     +     +  +                  |  47        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  50        |
      Leukemia Mononuclear                 |          X                 X           X                                 |         10 |
      Neoplastic Nodule                    |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               | +                 +                                                      |   6        |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +        +     +  +     +  +  +  +  +  A     +     +  +                  |  49        |
      Leukemia Mononuclear                 |          X                 X                                             |          3 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |          +                             +                                 |  12        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  50        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +        +     +  +     +  +  +  +  +  A     +     +  +                  |  49        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +        +     +  +     +  M  +  +  +  +     +     +  +                  |  43        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |          +                             +                                 |  13        |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
      Leukemia Mononuclear                 |                                        X                                 |          2 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |          +                 +           +                                 |  14        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |          +                 +           +                                 |  13        |
      Leukemia Mononuclear                 |                            X           X                                 |          2 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |          +                 +           +                                 |  13        |
      Leukemia Mononuclear                 |                            X           X                                 |          2 |
      Pheochromocytoma Malignant           |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |          +        +              +     A                                 |  15        |
      Adenoma                              |                   X              X                                       |          3 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  18                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 1| 5| 4| 7| 7| 1| 7| 6| 7| 7| 6| 5| 4| 7| 1| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 9| 9| 9| 6| 3| 3| 9| 2| 9| 2| 2| 7| 0| 6| 2| 9| 2| 2| 6|              |            |
                                           | 1| 3| 3| 6| 4| 1| 1| 3| 5| 6| 5| 5| 6| 4| 4| 3| 3| 5| 5| 6|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|              |     A      |
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +        +     M  +     +  +  +  +  +  M     M     +  +                  |  39        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +        +     +  +     +  +  +  +  +  M     +     +  +                  |  49        |
      Pars Distalis, Adenoma               | X        X     X           X                 X        X                  |         27 |
      Pars Distalis, Adenoma, Multiple     |                   X              X                 X                     |          4 |
      Pars Distalis, Carcinoma             |                                                                          |          1 |
      Pars Distalis, Leukemia Mononuclear  |                            X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +        +     +  +     +  +  +  +     +     +     +  +                  |  43        |
      C-Cell, Adenoma                      |                                                                          |          3 |
      C-Cell, Carcinoma                    |                                              X                           |          3 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          |          +     +  +     +     +  +     +                                 |  20        |
      Adenoma                              |                         X        X                                       |          4 |
      Carcinoma                            |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Ovary                                   |          +              +           M  +                                 |  17        |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  50        |
      Polyp Stromal                        |                               X  X                                       |          8 |
      Polyp Stromal, Multiple              |                                                                          |          1 |
      Sarcoma Stromal                      |                                     X                                    |          2 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood                                   |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |          +                             A                                 |  11        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |          +     +  +        +        +  +                                 |  25        |
      Lumbar, Leukemia Mononuclear         |                                                                          |          1 |
      Mediastinal, Leukemia Mononuclear    |                            X                                             |          1 |
      Pancreatic, Leukemia Mononuclear     |                                                                          |          1 |
      Renal, Leukemia Mononuclear          |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  |          +     +           +        +  +                                 |  19        |
      Leukemia Mononuclear                 |          X                 X           X                                 |          4 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |          +        +                    +                                 |  14        |
      Leukemia Mononuclear                 |          X                                                               |          3 |
                                            __________________________________________________________________________|____________|
   Spleen                                  |          +                 +           +                                 |  23        |
      Leukemia Mononuclear                 |          X                 X           X                                 |          8 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |          +                             M                                 |  10        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  19                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 1| 5| 4| 7| 7| 1| 7| 6| 7| 7| 6| 5| 4| 7| 1| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 9| 9| 9| 6| 3| 3| 9| 2| 9| 2| 2| 7| 0| 6| 2| 9| 2| 2| 6|              |            |
                                           | 1| 3| 3| 6| 4| 1| 1| 3| 5| 6| 5| 5| 6| 4| 4| 3| 3| 5| 5| 6|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|              |     A      |
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Metastatic, Lung                 |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +        +              +     +  +  +  +     +     +  +                  |  36        |
      Fibroadenoma                         |                         X                    X     X                     |         17 |
      Fibroadenoma, Multiple               | X                             X  X  X                 X                  |         10 |
                                            __________________________________________________________________________|____________|
   Skin                                    |          +                             +                                 |  15        |
      Subcutaneous Tissue, Fibroma         |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |          +                             +                                 |  13        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |          +     +                       +                                 |  15        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Medulla, Carcinoma, Metastatic,      |                                                                          |            |
          Pituitary Gland                  |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                +                                                         |   2        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |          +        +        +        +  +                                 |  20        |
      Alveolar/Bronchiolar Carcinoma       |                                                                          |          1 |
      Leukemia Mononuclear                 |          X                 X           X                                 |          4 |
      Pheochromocytoma Malignant,          |                                                                          |            |
          Metastatic                       |                                                                          |          1 |
      Sarcoma, Metastatic, Lung            |                                     X                                    |          1 |
      Pleura, Alveolar/Bronchiolar         |                                                                          |            |
          Carcinoma, Metastatic, Lung      |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    |          +                             +                                 |  12        |
                                            __________________________________________________________________________|____________|
   Trachea                                 |          +                             +                                 |  12        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                +                                                         |   2        |
                                            __________________________________________________________________________|____________|
   Eye                                     | I        +     +           I                                             |   8        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |          +                                                               |   4        |
                                            __________________________________________________________________________|____________|
   Zymbal's Gland                          |                                                                          |   2        |
      Squamous Cell Carcinoma              |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  20                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 1| 5| 4| 7| 7| 1| 7| 6| 7| 7| 6| 5| 4| 7| 1| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 9| 9| 9| 6| 3| 3| 9| 2| 9| 2| 2| 7| 0| 6| 2| 9| 2| 2| 6|              |            |
                                           | 1| 3| 3| 6| 4| 1| 1| 3| 5| 6| 5| 5| 6| 4| 4| 3| 3| 5| 5| 6|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|              |     A      |
    0.1% LF                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +        +     +  +     +  +  +  +  +  A     +     +  +                  |  49        |
      Leukemia Mononuclear                 |          X                 X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  49        |
      Leukemia Mononuclear                 |          X                                                               |          2 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +        +     +  +     +  +  +  +  +  +     +     +  +                  |  50        |
      Leukemia Mononuclear                 |          X                 X           X                                 |         10 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  21                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 1| 7| 6| 4| 1| 7| 7| 7| 7| 6| 7| 7| 7| 5| 4|             
                             DAY ON TEST   | 2| 3| 9| 1| 0| 2| 2| 2| 6| 6| 9| 2| 6| 6| 9| 2| 2| 2| 0| 6| 2| 2| 2| 2| 6|             
                                           | 4| 1| 1| 8| 7| 9| 4| 5| 6| 4| 1| 3| 6| 4| 1| 4| 4| 9| 9| 0| 3| 4| 4| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|             
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |                                                                      +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                                                                      +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                                                                      +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                                                      +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                                                      +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +     +  +  +  +  +           +  +        +  +  +  M  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +     +  +  +  +  M           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |          X  X                                      X  X  X               |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                              +                           |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |          X                                            X  X               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                                                      +   |             
      Submandibular Gland, Leukemia        |                                                                          |             
          Mononuclear                      |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +     +  M  +  +  +           +  +        +  +  +  M  +  +  +  +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                                      +   |             
      Fibrosarcoma, Metastatic, Skin       |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |          +                                         +  +              +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |          +                                         +  +              +   |             
      Adenoma                              |                                                                          |             
      Fibrosarcoma, Metastatic, Skin       |                                                                          |             
      Leukemia Mononuclear                 |                                                    X                     |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |          +                                         +  +              +   |             
      Leukemia Mononuclear                 |          X                                         X                     |             
      Pheochromocytoma Benign              |                                                    X                     |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |                                     +                                +   |             
      Adenoma                              |                                     X                                    |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +     M  +  M  +  +           +  +        +  +  M  M  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Pars Distalis, Adenoma               |          X           X           X  X        X  X  X        X            |             
      Pars Distalis, Adenoma, Multiple     |    X           X                                         X     X  X      |             
      Pars Distalis, Leukemia Mononuclear  |          X                                         X                     |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  22                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 1| 7| 6| 4| 1| 7| 7| 7| 7| 6| 7| 7| 7| 5| 4|             
                             DAY ON TEST   | 2| 3| 9| 1| 0| 2| 2| 2| 6| 6| 9| 2| 6| 6| 9| 2| 2| 2| 0| 6| 2| 2| 2| 2| 6|             
                                           | 4| 1| 1| 8| 7| 9| 4| 5| 6| 4| 1| 3| 6| 4| 1| 4| 4| 9| 9| 0| 3| 4| 4| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|             
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      C-Cell, Adenoma                      |                X                                      X                  |             
      C-Cell, Carcinoma                    |    X        X                                                            |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +           +                                +                       +   |             
      Adenoma                              |             X                                                            |             
      Carcinoma                            |                                                                          |             
      Sarcoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  M     M  +  M  M  M           M  M        +  M  M  M  M  M  +  M  +   |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Adenocarcinoma                       |                                                                          |             
      Polyp Stromal                        |    X           X     X           X  X           X           X  X     X   |             
      Sarcoma Stromal                      |                                                                          |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                     +                                    |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                                                      +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |          +     +                             +     +           +  +  +   |             
      Lumbar, Fibrosarcoma, Metastatic,    |                                                                          |             
           Skin                            |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                    X                     |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |                                              +     +           +     +   |             
      Leukemia Mononuclear                 |                                                    X                     |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |          +     +                                   +                 +   |             
      Leukemia Mononuclear                 |          X                                         X                     |             
                                            __________________________________________________________________________|             
   Spleen                                  |          +                          +        +     +  +  +     +     +   |             
      Leukemia Mononuclear                 |          X                                         X  X  X               |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                                                      +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +        +  +     +              +                    +  +  +     +   |             
      Adenocarcinoma                       |                X                                         X               |             
      Fibroadenoma                         |             X        X              X                    X  X  X         |             
      Fibroadenoma, Multiple               |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                                     +                                +   |             
      Subcutaneous Tissue, Fibroma         |                                                                      X   |             
      Subcutaneous Tissue, Fibrosarcoma    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  23                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 1| 7| 6| 4| 1| 7| 7| 7| 7| 6| 7| 7| 7| 5| 4|             
                             DAY ON TEST   | 2| 3| 9| 1| 0| 2| 2| 2| 6| 6| 9| 2| 6| 6| 9| 2| 2| 2| 0| 6| 2| 2| 2| 2| 6|             
                                           | 4| 1| 1| 8| 7| 9| 4| 5| 6| 4| 1| 3| 6| 4| 1| 4| 4| 9| 9| 0| 3| 4| 4| 1| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8| 8|             
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                                                      +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |                                     +                                +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |             +                                         +  +  +     +  +   |             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Leukemia Mononuclear                 |                                                       X                  |             
                                            __________________________________________________________________________|             
   Nose                                    |                                                                      +   |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                                                      +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                  +                                       |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |    +                                                                     |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |          X                                         X                     |             
      Renal Tubule, Adenoma                |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +     +  +  +  +  +           +  +        +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |          X  X                                      X  X  X               |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  24                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 7| 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 7| 7| 7| 6| 4| 7| 7| 7| 6| 1|             
                             DAY ON TEST   | 3| 2| 2| 6| 2| 2| 2| 9| 3| 2| 2| 2| 2| 6| 6| 2| 3| 2| 0| 6| 2| 2| 2| 0| 9|             
                                           | 1| 9| 4| 4| 4| 4| 4| 1| 1| 9| 4| 4| 5| 6| 6| 4| 1| 5| 3| 4| 3| 9| 5| 5| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|             
    1.0% MF                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |                                                       +              +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                                  +                    +              +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                                  +                    +              +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                                       +              +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                                       +              +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                     X           X     X                  |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                                       +              +   |             
      Submandibular Gland, Leukemia        |                                                                          |             
          Mononuclear                      |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +     +  +  +     +  +  +  +  +        +  +  M  +     +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                                       +              +   |             
      Fibrosarcoma, Metastatic, Skin       |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +                 +                                M  +              +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +                 +                                   +              +   |             
      Adenoma                              |                                                                          |             
      Fibrosarcoma, Metastatic, Skin       |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +                 +                                   +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Pheochromocytoma Benign              | X                 X                                                      |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |                                                       +              +   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +     +  +  +     M  M  +  M  +        M  +  +  +     +  +  +  +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Pars Distalis, Adenoma               |    X  X        X  X     X  X                          X        X     X   |             
      Pars Distalis, Adenoma, Multiple     | X           X                                                     X      |             
      Pars Distalis, Leukemia Mononuclear  |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +     +  +  +        +  +  +           +  +  +  +     +  +  +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  25                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 7| 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 7| 7| 7| 6| 4| 7| 7| 7| 6| 1|             
                             DAY ON TEST   | 3| 2| 2| 6| 2| 2| 2| 9| 3| 2| 2| 2| 2| 6| 6| 2| 3| 2| 0| 6| 2| 2| 2| 0| 9|             
                                           | 1| 9| 4| 4| 4| 4| 4| 1| 1| 9| 4| 4| 5| 6| 6| 4| 1| 5| 3| 4| 3| 9| 5| 5| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|             
    1.0% MF                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      C-Cell, Adenoma                      |                   X                                                      |             
      C-Cell, Carcinoma                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          | +                 +                 +                 +        +     +   |             
      Adenoma                              | X                                   X                                    |             
      Carcinoma                            |                                                                X         |             
      Sarcoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  M  M     M  M  M     M  M  M  +  M        M  M  M  +     +  M  M  +   |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Adenocarcinoma                       |                                     X                                    |             
      Polyp Stromal                        |                                     X           X  X           X         |             
      Sarcoma Stromal                      |                X                                                         |             
                                            __________________________________________________________________________|             
   Vagina                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                                       +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |                                     +                 +              +   |             
      Lumbar, Fibrosarcoma, Metastatic,    |                                                                          |             
           Skin                            |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |                                                       +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                     +                 +              +   |             
      Leukemia Mononuclear                 |                                     X                                    |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +                                      +        +              +   |             
      Leukemia Mononuclear                 |                                                       X                  |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                                       +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +           +     +                             +     +        +  +  +   |             
      Adenocarcinoma                       |             X                                                            |             
      Fibroadenoma                         | X           X                                   X              X     X   |             
      Fibroadenoma, Multiple               |                                                                   X      |             
                                            __________________________________________________________________________|             
   Skin                                    |                                                       +              +   |             
      Subcutaneous Tissue, Fibroma         |                                                                          |             
      Subcutaneous Tissue, Fibrosarcoma    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  26                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 4| 7| 7| 7| 1| 7| 7| 7| 7| 7| 4| 4| 7| 7| 7| 6| 4| 7| 7| 7| 6| 1|             
                             DAY ON TEST   | 3| 2| 2| 6| 2| 2| 2| 9| 3| 2| 2| 2| 2| 6| 6| 2| 3| 2| 0| 6| 2| 2| 2| 0| 9|             
                                           | 1| 9| 4| 4| 4| 4| 4| 1| 1| 9| 4| 4| 5| 6| 6| 4| 1| 5| 3| 4| 3| 9| 5| 5| 1|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|             
    1.0% MF                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                                       +              +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |                                                       +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +                          +              +        +        +     +   |             
      Alveolar/Bronchiolar Adenoma         |    X                                                                     |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |                                                       +              +   |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                                       +              +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                             +            |             
                                            __________________________________________________________________________|             
   Eye                                     |                         +                       +           +            |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Renal Tubule, Adenoma                | X                                                                        |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +     +  +  +     +  +  +  +  +        +  +  +  +     +  +  +  +   |             
      Leukemia Mononuclear                 |                                     X           X     X                  |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  27                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 7| 7| 4| 7| 6| 1| 5| 3| 7| 7| 6| 5| 1| 1| 6| 4| 1| 4|              |            |
                             DAY ON TEST   | 2| 9| 2| 2| 6| 2| 9| 9| 4| 3| 2| 2| 9| 4| 9| 9| 8| 6| 9| 4|              |            |
                                           | 3| 3| 9| 5| 6| 3| 7| 3| 8| 7| 3| 5| 7| 8| 3| 3| 5| 6| 3| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|              |     A      |
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |                         +  +           +                 +               |   7        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |                         +  +           +                 +               |   8        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |                         +  +           +                 +               |   8        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |                         +  +           +                 +               |   7        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |                         +  +           +                 +               |   7        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +     +  +     +  +     +  +  +  +  +  +        +        +               |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +     +  +     +  +     +  +  +  +  +  +        +        +               |  49        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Leukemia Mononuclear                 |       X        X  X     X              X                                 |         13 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |          +        M                                                      |   2        |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Leukemia Mononuclear                 |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |                         +  +           +                 +               |   7        |
      Submandibular Gland, Leukemia        |                                                                          |            |
          Mononuclear                      |                                        X                                 |          1 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +     +  +     M  M     +  +  +  +  M  +        +        +               |  43        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |                         +  +           +                 +               |   7        |
      Fibrosarcoma, Metastatic, Skin       |                                                          X               |          1 |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |                   +     +  +           +                 +               |  13        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |                   +     +  +           +                 +               |  13        |
      Adenoma                              |                   X                                                      |          1 |
      Fibrosarcoma, Metastatic, Skin       |                                                          X               |          1 |
      Leukemia Mononuclear                 |                         X              X                                 |          3 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |                         +  +           +                 +               |  12        |
      Leukemia Mononuclear                 |                                        X                                 |          3 |
      Pheochromocytoma Benign              |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |                         +  +           +                 +               |   8        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M     +  M     +  M     +  M  +  M  +  +        +        M               |  36        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  28                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 7| 7| 4| 7| 6| 1| 5| 3| 7| 7| 6| 5| 1| 1| 6| 4| 1| 4|              |            |
                             DAY ON TEST   | 2| 9| 2| 2| 6| 2| 9| 9| 4| 3| 2| 2| 9| 4| 9| 9| 8| 6| 9| 4|              |            |
                                           | 3| 3| 9| 5| 6| 3| 7| 3| 8| 7| 3| 5| 7| 8| 3| 3| 5| 6| 3| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|              |     A      |
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Pars Distalis, Adenoma               | X     X        X              X  X  X  X        X        X               |         26 |
      Pars Distalis, Adenoma, Multiple     |                   X                                                      |          9 |
      Pars Distalis, Leukemia Mononuclear  |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +     +  +     +  +     +  +  +  +  +  +        +        +               |  47        |
      C-Cell, Adenoma                      |          X                                                               |          4 |
      C-Cell, Carcinoma                    |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          |                   +     +  +           +                 M               |  14        |
      Adenoma                              |                                                                          |          3 |
      Carcinoma                            |                   X                                                      |          2 |
      Sarcoma                              |                         X                                                |          1 |
                                            __________________________________________________________________________|____________|
   Ovary                                   | M     M  M     +  M     +  +  M  M  M  +        M        +               |  15        |
                                            __________________________________________________________________________|____________|
   Uterus                                  | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Adenocarcinoma                       |                                                                          |          1 |
      Polyp Stromal                        |          X                    X                 X                        |         16 |
      Sarcoma Stromal                      |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Vagina                                  |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |                         +  +           +                 +               |   7        |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |          +        +     +  +     +     +                 +               |  17        |
      Lumbar, Fibrosarcoma, Metastatic,    |                                                                          |            |
           Skin                            |                                                          X               |          1 |
      Mediastinal, Leukemia Mononuclear    |                   X                                                      |          1 |
      Pancreatic, Leukemia Mononuclear     |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  |                         M  +     +     +                 +               |  10        |
      Leukemia Mononuclear                 |                                        X                                 |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |          +              +  +           +                 +               |  12        |
      Leukemia Mononuclear                 |                                        X                                 |          4 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +                 +     +  +           +                 +               |  20        |
      Leukemia Mononuclear                 |                   X     X              X                                 |          8 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |                         +  +           +                 +               |   7        |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  29                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 1| 7| 7| 4| 7| 6| 1| 5| 3| 7| 7| 6| 5| 1| 1| 6| 4| 1| 4|              |            |
                             DAY ON TEST   | 2| 9| 2| 2| 6| 2| 9| 9| 4| 3| 2| 2| 9| 4| 9| 9| 8| 6| 9| 4|              |            |
                                           | 3| 3| 9| 5| 6| 3| 7| 3| 8| 7| 3| 5| 7| 8| 3| 3| 5| 6| 3| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9| 9|              |     A      |
    1.0% MF                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |       +        +        +  M        +  +        +        +               |  24        |
      Adenocarcinoma                       |                                                                          |          3 |
      Fibroadenoma                         |       X        X                    X                                    |         14 |
      Fibroadenoma, Multiple               |                                                 X                        |          2 |
                                            __________________________________________________________________________|____________|
   Skin                                    |                         +  +           +                 +               |   8        |
      Subcutaneous Tissue, Fibroma         |                                                                          |          1 |
      Subcutaneous Tissue, Fibrosarcoma    |                                                          X               |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |                         +  +           +                 +               |   7        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |                         +  +           +                 +               |   8        |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |          +        +     +  +        +  +                 +               |  20        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          1 |
      Leukemia Mononuclear                 |                   X     X              X                                 |          4 |
                                            __________________________________________________________________________|____________|
   Nose                                    |                         +  +           +                 +               |   7        |
                                            __________________________________________________________________________|____________|
   Trachea                                 |                         +  +           +                 +               |   7        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Eye                                     |          +              I              +                                 |   6        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |          +                                                               |   2        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Renal Tubule, Adenoma                |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +     +  +     +  +     +  +  +  +  +  +        +        +               |  50        |
      Leukemia Mononuclear                 |       X        X  X     X              X                                 |         13 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  30                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 4| 4| 7| 1| 7| 7| 1| 7| 7| 5| 5| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 4| 4|             
                             DAY ON TEST   | 2| 8| 9| 6| 1| 9| 2| 2| 9| 1| 2| 5| 6| 2| 2| 3| 3| 2| 2| 6| 3| 2| 3| 6| 6|             
                                           | 4| 8| 2| 4| 6| 1| 3| 4| 1| 5| 3| 3| 0| 5| 3| 1| 1| 5| 4| 8| 1| 4| 1| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  M     +     +  +     +  +  +  +  +  +  M  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +     +     +  +     +  +     +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +     +     +  +     +  +     +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +     +     +  +     +  +     +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +     +     +  +     +  +     +  +  +  +  +  +  +  +  +  +  +      |             
      Polyp Adenomatous                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +     +     +  +     +  +  A  +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +     +     +  +     +  +  A  +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +     +     +  +     +  +  A  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +     +     +  +     +  +  A  +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |    X                                         X     X     X        X      |             
      Neoplastic Nodule                    |                   X                                                      |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Adenoma                              |                                                                          |             
      Leukemia Monocytic                   |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |       +                          +  +                                    |             
      Submandibular Gland, Leukemia        |                                                                          |             
          Mononuclear                      |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +     +     +  +     +  +  +  +  +     +     +  +     +  +  +      |             
      Squamous Cell Carcinoma              |       X                                                                  |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                          X               |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Adenoma                              |                                              X                           |             
      Leukemia Mononuclear                 |                                                          X               |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  31                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 4| 4| 7| 1| 7| 7| 1| 7| 7| 5| 5| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 4| 4|             
                             DAY ON TEST   | 2| 8| 9| 6| 1| 9| 2| 2| 9| 1| 2| 5| 6| 2| 2| 3| 3| 2| 2| 6| 3| 2| 3| 6| 6|             
                                           | 4| 8| 2| 4| 6| 1| 3| 4| 1| 5| 3| 3| 0| 5| 3| 1| 1| 5| 4| 8| 1| 4| 1| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pheochromocytoma Benign              |                               X                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +     +     +  +     +  +     +  +  +  +  +  +  +  +  +  +  +      |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  M  +  +  +      |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +     +     +  +     +  +  M  +  +  +  +  +  +  +  +  +  +  +      |             
      Pars Distalis, Adenoma               | X  X              X        X  X           X     X           X            |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
      Pars Distalis, Carcinoma             |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                                                                          |             
      Pars Intermedia, Leukemia Mononuclear|                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      C-Cell, Adenoma                      |                                                                          |             
      C-Cell, Carcinoma                    |                                                                          |             
      Follicular Cell, Adenoma             |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |       +                    +  +  +  +                                    |             
      Adenoma                              |                            X  X                                          |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  M  +      |             
      Granulosa-Theca Tumor Malignant      |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Polyp Stromal                        | X                                                                        |             
      Polyp Stromal, Multiple              |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |       +                          +  +                                    |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  M      |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +     +     +  +     +  +  +  M  +  M  +  +  +  +  +  +  +  M      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +                             A  +                                    |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |    X                                         X     X     X        X      |             
                                            __________________________________________________________________________|             
   Thymus                                  |       +                          +  M                                    |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |       +                    +  +  +  +     +     +     +        +         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  32                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 4| 4| 7| 1| 7| 7| 1| 7| 7| 5| 5| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 4| 4|             
                             DAY ON TEST   | 2| 8| 9| 6| 1| 9| 2| 2| 9| 1| 2| 5| 6| 2| 2| 3| 3| 2| 2| 6| 3| 2| 3| 6| 6|             
                                           | 4| 8| 2| 4| 6| 1| 3| 4| 1| 5| 3| 3| 0| 5| 3| 1| 1| 5| 4| 8| 1| 4| 1| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Adenocarcinoma                       |                            X                                             |             
      Fibroadenoma                         |                                           X           X                  |             
      Fibroadenoma, Multiple               |                               X                 X              X         |             
                                            __________________________________________________________________________|             
   Skin                                    |       +                          +  +                                    |             
      Subcutaneous Tissue, Sarcoma, Poorly |                                                                          |             
          Differentiated                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |       +                       +     +                          +         |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Sarcoma                              |                                                                          |             
      Intercostal, Leukemia Mononuclear    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Carcinoma, Extension, Metastatic,    |                                                                          |             
           Pituitary Gland                 |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
      Choroid Plexus, Leukemia Mononuclear |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Granulosa-Theca Tumor Malignant,     |                                                                          |             
           Metastatic, Ovary               |                                                                          |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Uncertain Primary Site          |                                     X                                    |             
      Leukemia Mononuclear                 |    X                                               X     X               |             
      Sarcoma, Metastatic, Poorly          |                                                                          |             
          Differentiated, Skin             |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |       +                          A  +                                    |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +                             +                                       |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  33                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 4| 4| 7| 1| 7| 7| 1| 7| 7| 5| 5| 7| 7| 7| 7| 7| 7| 6| 7| 7| 7| 4| 4|             
                             DAY ON TEST   | 2| 8| 9| 6| 1| 9| 2| 2| 9| 1| 2| 5| 6| 2| 2| 3| 3| 2| 2| 6| 3| 2| 3| 6| 6|             
                                           | 4| 8| 2| 4| 6| 1| 3| 4| 1| 5| 3| 3| 0| 5| 3| 1| 1| 5| 4| 8| 1| 4| 1| 6| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +     +     +  +     +  +  +  +  +  +  +  +  +  +  +  +  +  +      |             
      Leukemia Monocytic                   |                                                                          |             
      Leukemia Mononuclear                 |    X                                         X     X     X        X      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  34                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 4| 1| 5| 4| 2| 1| 7| 7| 6| 1| 4| 7| 7| 7| 5| 4| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 9| 2| 6| 9| 9| 6| 8| 9| 3| 2| 3| 9| 5| 2| 2| 1| 9| 6| 9| 2| 6| 2| 6|             
                                           | 1| 4| 1| 4| 6| 1| 7| 6| 4| 1| 1| 4| 0| 3| 7| 3| 3| 6| 4| 4| 3| 3| 7| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +     M        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Polyp Adenomatous                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 | X  X                                X              X                 X   |             
      Neoplastic Nodule                    |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                     +                                    |             
      Leukemia Mononuclear                 |                                     X                                    |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Adenoma                              |                                                                          |             
      Leukemia Monocytic                   |                                                                          |             
      Leukemia Mononuclear                 |                                     X                                X   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                   +     +           +     +           +              +   |             
      Submandibular Gland, Leukemia        |                                                                          |             
          Mononuclear                      |                                     X                                X   |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +     +        +           +  +  +     +  +  +     +        +         |             
      Squamous Cell Carcinoma              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                     X              X                 X   |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Adenoma                              |                                                                          |             
      Leukemia Mononuclear                 |                                     X              X                 X   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                     X              X                 X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  35                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 4| 1| 5| 4| 2| 1| 7| 7| 6| 1| 4| 7| 7| 7| 5| 4| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 9| 2| 6| 9| 9| 6| 8| 9| 3| 2| 3| 9| 5| 2| 2| 1| 9| 6| 9| 2| 6| 2| 6|             
                                           | 1| 4| 1| 4| 6| 1| 7| 6| 4| 1| 1| 4| 0| 3| 7| 3| 3| 6| 4| 4| 3| 3| 7| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +     M        +     +     +  +  M     M  M  M  +  +        +  +  +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Pars Distalis, Adenoma               |          X        X           X  X           X     X  X        X  X      |             
      Pars Distalis, Adenoma, Multiple     |                                                 X                        |             
      Pars Distalis, Carcinoma             |    X                                                                     |             
      Pars Distalis, Leukemia Mononuclear  |                                                                      X   |             
      Pars Intermedia, Leukemia Mononuclear|                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      C-Cell, Adenoma                      |          X                                                               |             
      C-Cell, Carcinoma                    |                                                                          |             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Clitoral Gland                          |          +              +           +     +                              |             
      Adenoma                              |          X                                                               |             
                                            __________________________________________________________________________|             
   Ovary                                   | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Granulosa-Theca Tumor Malignant      |                                     X                                    |             
      Leukemia Mononuclear                 |                                     X              X                 X   |             
                                            __________________________________________________________________________|             
   Uterus                                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Polyp Stromal                        | X                       X     X                                X         |             
      Polyp Stromal, Multiple              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                   +     +           +     +           +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Mediastinal, Leukemia Mononuclear    |                                     X                                X   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +     +        +     M     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |    X                                X                                X   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                   +     M                 +           +              +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 | X  X                                X              X                 X   |             
                                            __________________________________________________________________________|             
   Thymus                                  |                   +     +           +     M           +              +   |             
      Leukemia Mononuclear                 |                                     X                                X   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |          +        +     +           +     +           +        +     +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  36                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 4| 1| 5| 4| 2| 1| 7| 7| 6| 1| 4| 7| 7| 7| 5| 4| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 9| 2| 6| 9| 9| 6| 8| 9| 3| 2| 3| 9| 5| 2| 2| 1| 9| 6| 9| 2| 6| 2| 6|             
                                           | 1| 4| 1| 4| 6| 1| 7| 6| 4| 1| 1| 4| 0| 3| 7| 3| 3| 6| 4| 4| 3| 3| 7| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Adenocarcinoma                       |                                                                          |             
      Fibroadenoma                         |          X                                                     X         |             
      Fibroadenoma, Multiple               |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                   +     +           +     +           +              +   |             
      Subcutaneous Tissue, Sarcoma, Poorly |                                                                          |             
          Differentiated                   |                         X                                                |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                   +     +        +  +     +           +              +   |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                     +     +                       +      |             
      Sarcoma                              |                                                                   X      |             
      Intercostal, Leukemia Mononuclear    |                                     X                                    |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Carcinoma, Extension, Metastatic,    |                                                                          |             
           Pituitary Gland                 |    X                                                                     |             
      Leukemia Mononuclear                 |                                                    X                 X   |             
      Choroid Plexus, Leukemia Mononuclear |                                     X                                    |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                   +      |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Granulosa-Theca Tumor Malignant,     |                                                                          |             
           Metastatic, Ovary               |                                     X                                    |             
      Hepatocellular Carcinoma, Metastatic,|                                                                          |             
           Uncertain Primary Site          |                                                                          |             
      Leukemia Mononuclear                 |    X                                X              X                 X   |             
      Sarcoma, Metastatic, Poorly          |                                                                          |             
          Differentiated, Skin             |                         X                                                |             
                                            __________________________________________________________________________|             
   Nose                                    |                   +     +           +     +           +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                       +                  |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                   +                                   +                  |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                     X              X                 X   |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  37                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 1| 7| 4| 1| 5| 4| 2| 1| 7| 7| 6| 1| 4| 7| 7| 7| 5| 4| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 3| 2| 9| 2| 6| 9| 9| 6| 8| 9| 3| 2| 3| 9| 5| 2| 2| 1| 9| 6| 9| 2| 6| 2| 6|             
                                           | 1| 4| 1| 4| 6| 1| 7| 6| 4| 1| 1| 4| 0| 3| 7| 3| 3| 6| 4| 4| 3| 3| 7| 3| 6|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    4.0% HF                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +     +        +     +     +  +  +     +  +  +  +  +        +  +  +   |             
      Leukemia Monocytic                   |                                                                          |             
      Leukemia Mononuclear                 | X  X                                X              X                 X   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  38                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 6| 4| 7| 7| 6| 6| 1| 1| 6| 5| 6| 6| 7| 7| 7| 4| 4|              |            |
                             DAY ON TEST   | 9| 2| 2| 8| 6| 3| 2| 8| 3| 9| 9| 3| 4| 6| 8| 2| 2| 3| 6| 6|              |            |
                                           | 3| 3| 4| 8| 6| 1| 9| 6| 2| 3| 3| 7| 9| 0| 8| 3| 3| 1| 6| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |    +  +  +     +  +  +  +        +  +  +  +  +  +                        |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  48        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  48        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  47        |
      Polyp Adenomatous                    |                                     X                                    |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small                         |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Liver                                   |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                       X                                       |         12 |
      Neoplastic Nodule                    |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   1        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Adenoma                              |                   X                                                      |          1 |
      Leukemia Monocytic                   |                                  X                                       |          1 |
      Leukemia Mononuclear                 |          X                       X                                       |          4 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |                                  +  +                                    |  11        |
      Submandibular Gland, Leukemia        |                                                                          |            |
          Mononuclear                      |                                  X                                       |          3 |
                                            __________________________________________________________________________|____________|
   Stomach                                 |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    |       +  +     +  +  +  +        +  +  +  +  +     +                     |  47        |
      Leukemia Mononuclear                 |          X                                                               |          2 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                                                               |          2 |
                                            __________________________________________________________________________|____________|
   Tongue                                  |    +  +        +  +                 +  +  +  +  +  +                     |  39        |
      Squamous Cell Carcinoma              |                                        X                                 |          2 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                       X                                       |          6 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  39                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 6| 4| 7| 7| 6| 6| 1| 1| 6| 5| 6| 6| 7| 7| 7| 4| 4|              |            |
                             DAY ON TEST   | 9| 2| 2| 8| 6| 3| 2| 8| 3| 9| 9| 3| 4| 6| 8| 2| 2| 3| 6| 6|              |            |
                                           | 3| 3| 4| 8| 6| 1| 9| 6| 2| 3| 3| 7| 9| 0| 8| 3| 3| 1| 6| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Adenoma                              |                                                                          |          1 |
      Leukemia Mononuclear                 |          X                       X                                       |          6 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                       X                                       |          5 |
      Pheochromocytoma Benign              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       |    +  +  +     +  +  +  +        M  +  +  +  +  +  +                     |  43        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
      Pars Distalis, Adenoma               |          X     X     X  X           X     X  X     X                     |         25 |
      Pars Distalis, Adenoma, Multiple     |                                                 X                        |          2 |
      Pars Distalis, Carcinoma             |                                                                          |          1 |
      Pars Distalis, Leukemia Mononuclear  |          X                       X                                       |          3 |
      Pars Intermedia, Leukemia Mononuclear|                                  X                                       |          1 |
      Pars Nervosa, Leukemia Mononuclear   |                                  X                                       |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      C-Cell, Adenoma                      |                                           X                              |          2 |
      C-Cell, Carcinoma                    |                X                                                         |          1 |
      Follicular Cell, Adenoma             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Clitoral Gland                          |                         +        +  +                                    |  12        |
      Adenoma                              |                         X                                                |          4 |
                                            __________________________________________________________________________|____________|
   Ovary                                   |    +  +  +     +  +  +  +        +  +  +  +  +  M  +                     |  48        |
      Granulosa-Theca Tumor Malignant      |                                                                          |          1 |
      Leukemia Mononuclear                 |                                  X                                       |          4 |
                                            __________________________________________________________________________|____________|
   Uterus                                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Polyp Stromal                        |    X           X  X     X                          X                     |         10 |
      Polyp Stromal, Multiple              |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |                                  +  +                                    |  11        |
      Leukemia Mononuclear                 |                                  X                                       |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  49        |
      Mediastinal, Leukemia Mononuclear    |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  46        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  40                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 6| 4| 7| 7| 6| 6| 1| 1| 6| 5| 6| 6| 7| 7| 7| 4| 4|              |            |
                             DAY ON TEST   | 9| 2| 2| 8| 6| 3| 2| 8| 3| 9| 9| 3| 4| 6| 8| 2| 2| 3| 6| 6|              |            |
                                           | 3| 3| 4| 8| 6| 1| 9| 6| 2| 3| 3| 7| 9| 0| 8| 3| 3| 1| 6| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |          X                       X                                       |          5 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |          +                       +  +                                    |   9        |
      Leukemia Mononuclear                 |          X                       X                                       |          3 |
                                            __________________________________________________________________________|____________|
   Spleen                                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                       X                                       |         12 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |          M                       +  +                                    |   9        |
      Leukemia Mononuclear                 |                                                                          |          2 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |                      +  +        +  +              +                     |  22        |
      Adenocarcinoma                       |                      X                                                   |          2 |
      Fibroadenoma                         |                                     X              X                     |          6 |
      Fibroadenoma, Multiple               |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Skin                                    |                                  +  +                                    |  11        |
      Subcutaneous Tissue, Sarcoma, Poorly |                                                                          |            |
          Differentiated                   |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |                   +              +  +                                    |  14        |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   3        |
      Sarcoma                              |                                                                          |          1 |
      Intercostal, Leukemia Mononuclear    |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Carcinoma, Extension, Metastatic,    |                                                                          |            |
           Pituitary Gland                 |                                                                          |          1 |
      Leukemia Mononuclear                 |                                  X                                       |          3 |
      Choroid Plexus, Leukemia Mononuclear |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                  +                                       |   2        |
      Leukemia Mononuclear                 |                                  X                                       |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Granulosa-Theca Tumor Malignant,     |                                                                          |            |
           Metastatic, Ovary               |                                                                          |          1 |
      Hepatocellular Carcinoma, Metastatic,|                                                                          |            |
           Uncertain Primary Site          |                                                                          |          1 |
      Leukemia Mononuclear                 |          X                       X                                       |          9 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  41                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 1| 7| 7| 6| 4| 7| 7| 6| 6| 1| 1| 6| 5| 6| 6| 7| 7| 7| 4| 4|              |            |
                             DAY ON TEST   | 9| 2| 2| 8| 6| 3| 2| 8| 3| 9| 9| 3| 4| 6| 8| 2| 2| 3| 6| 6|              |            |
                                           | 3| 3| 4| 8| 6| 1| 9| 6| 2| 3| 3| 7| 9| 0| 8| 3| 3| 1| 6| 4|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS FEMALE                 | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     T      |
                               ANIMAL ID   | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    4.0% HF                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Sarcoma, Metastatic, Poorly          |                                                                          |            |
          Differentiated, Skin             |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    |                                  +  +                                    |  10        |
      Leukemia Mononuclear                 |                                  X                                       |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                        +  +                              |   5        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   2        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |          X                       X                                       |          5 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         |    +  +  +     +  +  +  +        +  +  +  +  +  +  +                     |  50        |
      Leukemia Monocytic                   |                                  X                                       |          1 |
      Leukemia Mononuclear                 |          X                       X                                       |         12 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  42                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 6| 7| 2| 5| 7| 4| 5| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 1| 7| 7| 6| 4| 7|             
                             DAY ON TEST   | 8| 3| 2| 2| 7| 2| 6| 6| 8| 8| 2| 2| 0| 7| 5| 2| 2| 2| 2| 8| 2| 2| 8| 6| 2|             
                                           | 9| 6| 9| 6| 3| 9| 5| 2| 9| 9| 9| 8| 4| 9| 8| 9| 9| 4| 4| 9| 4| 1| 2| 5| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +  +     +        +  +  +  +  M  +  +  +  +     +  +  A     +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  M  +     +  +  A     +|             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  A  +     +        +  +  +  +  +  +  +  +  +     +  +  A     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Hepatocellular Adenoma               |                                                 X                        |             
      Leukemia Mononuclear                 |    X                             X     X        X  X  X        X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Mesothelioma Malignant               |             X                                                            |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |    +        +                 +                                          |             
      Leukemia Mononuclear                 |    X                                                                     |             
      Mesothelioma Malignant               |             X                 X                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Mesothelioma Malignant               |             X                                                            |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  M  +  +  +     +        +  +  +  +  +  +     M                     |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +     +        +  +  +  +  +  M  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  |    +  +     M  +     +        +  +     +  +  +  +  +  +     M  +  +     +|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                                                    +                     |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                                           X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Schwannoma Benign                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  43                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 6| 7| 2| 5| 7| 4| 5| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 1| 7| 7| 6| 4| 7|             
                             DAY ON TEST   | 8| 3| 2| 2| 7| 2| 6| 6| 8| 8| 2| 2| 0| 7| 5| 2| 2| 2| 2| 8| 2| 2| 8| 6| 2|             
                                           | 9| 6| 9| 6| 3| 9| 5| 2| 9| 9| 9| 8| 4| 9| 8| 9| 9| 4| 4| 9| 4| 1| 2| 5| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |                                                 X  X  X           X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |                                                       X           X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |                                  X  X              X                     |             
      Pheochromocytoma Benign, Multiple    |                X                                                        X|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |       +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +  +     +        +  +  +  +  M  +  +  +  +     +  +  M     +|             
      Adenoma                              |                               X                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  A  M  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Pars Distalis, Adenoma               |                                        X                    X  X        X|             
      Pars Distalis, Leukemia Mononuclear  |    X                                            X                 X      |             
      Pars Distalis, Lymphoma Malignant    |                                                                          |             
          Lymphocytic                      |                                     X                                    |             
      Pars Intermedia, Lymphoma Malignant  |                                                                          |             
          Lymphocytic                      |                                     X                                    |             
      Pars Nervosa, Lymphoma Malignant     |                                                                          |             
          Lymphocytic                      |                                     X                                    |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      C-Cell, Adenoma                      |                                        X                                 |             
      C-Cell, Carcinoma                    |                                                                          |             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                        +  +                              |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Mesothelioma Malignant               |             X                 X                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +     M  +        +                    +                              |             
      Adenoma                              |                      X                                                   |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +  +     +        M  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Mesothelioma Malignant               |             X                                                            |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Mesothelioma Malignant               |             X                 X                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  44                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 6| 7| 2| 5| 7| 4| 5| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 1| 7| 7| 6| 4| 7|             
                             DAY ON TEST   | 8| 3| 2| 2| 7| 2| 6| 6| 8| 8| 2| 2| 0| 7| 5| 2| 2| 2| 2| 8| 2| 2| 8| 6| 2|             
                                           | 9| 6| 9| 6| 3| 9| 5| 2| 9| 9| 9| 8| 4| 9| 8| 9| 9| 4| 4| 9| 4| 1| 2| 5| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Interstitial Cell, Adenoma           |    X  X     X  X              X  X  X        X  X  X  X     X  X  X     X|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +     +  +        +                    +                              |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lumbar, Leukemia Mononuclear         |                                                                          |             
      Lumbar, Lymphoma Malignant           |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |    X                                            X                        |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Mediastinal, Sarcoma, Metastatic,    |                                                                          |             
           Uncertain Primary Site          |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                 X                 X      |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
          Lymphocytic                      |                                     X                                    |             
      Renal, Leukemia Mononuclear          |                                                                          |             
      Renal, Lymphoma Malignant Lymphocytic|                                     X                                    |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |    +  M  +  M  +     +        +  +  +  +  +  +  +  M  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                                              X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +        +        +  M  +  M  +     M  +           M  +      |             
      Leukemia Mononuclear                 |    X                                               X              X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                   X        X  X  X        X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  M  +           +           M  +  +  +  M  +  M                     |             
      Leukemia Mononuclear                 |    X                                                                     |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Mediastinum, Basosquamous Tumor NOS  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    M     M  +        +                    M     +                       +|             
      Fibroadenoma                         |                                                 X                       X|             
                                            __________________________________________________________________________|             
   Skin                                    |    +     +  +        +                 +  +     +                       +|             
      Basal Cell Carcinoma                 |                                                                          |             
      Squamous Cell Papilloma              |                                                                          |             
      Subcutaneous Tissue, Fibroma         |                                                                          |             
      Subcutaneous Tissue, Fibrosarcoma    |                                           X                              |             
      Subcutaneous Tissue, Lipoma          |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  45                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 6| 7| 2| 5| 7| 4| 5| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 1| 7| 7| 6| 4| 7|             
                             DAY ON TEST   | 8| 3| 2| 2| 7| 2| 6| 6| 8| 8| 2| 2| 0| 7| 5| 2| 2| 2| 2| 8| 2| 2| 8| 6| 2|             
                                           | 9| 6| 9| 6| 3| 9| 5| 2| 9| 9| 9| 8| 4| 9| 8| 9| 9| 4| 4| 9| 4| 1| 2| 5| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |          +  +                             +                              |             
      Osteoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                              +                           |             
      Sarcoma                              |                                              X                           |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                                              X      |             
      Choroid Plexus, Lymphoma Malignant   |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Choroid Plexus, Sarcoma, Metastatic, |                                                                          |             
           Uncertain Primary Site          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Alveolar/Bronchiolar Adenoma         |                                                                         X|             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Leukemia Mononuclear                 |    X                                   X        X  X  X        X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Osteosarcoma, Metastatic, Bone       |                                                                          |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic, Adrenal Gland        |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +     +     +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                               X                     |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |       M                                                                  |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Leukemia Mononuclear                 |    X                                            X              X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Mesothelioma Malignant               |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +  +  +  +  +     +        +  +  +  +  +  +  +  +  +     +  +  +     +|             
 _____________________________________________________________________________________________________________________|             
                                                             Page  46                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 6| 7| 2| 5| 7| 4| 5| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 1| 7| 7| 6| 4| 7|             
                             DAY ON TEST   | 8| 3| 2| 2| 7| 2| 6| 6| 8| 8| 2| 2| 0| 7| 5| 2| 2| 2| 2| 8| 2| 2| 8| 6| 2|             
                                           | 9| 6| 9| 6| 3| 9| 5| 2| 9| 9| 9| 8| 4| 9| 8| 9| 9| 4| 4| 9| 4| 1| 2| 5| 7|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Leukemia Mononuclear                 |    X                             X     X        X  X  X        X  X      |             
      Lymphoma Malignant Lymphocytic       |                                     X                                    |             
      Mesothelioma Malignant               |             X                 X                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  47                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 5| 4| 1| 7| 7| 4| 1| 7| 6| 4| 1| 4| 7| 7| 7| 7| 6| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 2| 2| 1| 9| 6| 8| 2| 2| 6| 9| 2| 5| 6| 9| 6| 2| 2| 2| 2| 5| 9| 2| 7| 6| 6|             
                                           | 7| 7| 7| 0| 5| 9| 7| 4| 5| 1| 9| 6| 5| 1| 3| 9| 9| 4| 4| 4| 1| 7| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  M   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Hepatocellular Adenoma               |    X                          X                                          |             
      Leukemia Mononuclear                 |          X                                                     X  X  X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Mesothelioma Malignant               |                                                                          |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                       X                  |             
                                            __________________________________________________________________________|             
   Mesentery                               |    +                                                              +      |             
      Leukemia Mononuclear                 |                                                                          |             
      Mesothelioma Malignant               |                                                                   X      |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Mesothelioma Malignant               |                                                                   X      |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +  +        +  +        +  +           M  +  +  +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Schwannoma Benign                    |       X                                                                  |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  48                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 5| 4| 1| 7| 7| 4| 1| 7| 6| 4| 1| 4| 7| 7| 7| 7| 6| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 2| 2| 1| 9| 6| 8| 2| 2| 6| 9| 2| 5| 6| 9| 6| 2| 2| 2| 2| 5| 9| 2| 7| 6| 6|             
                                           | 7| 7| 7| 0| 5| 9| 7| 4| 5| 1| 9| 6| 5| 1| 3| 9| 9| 4| 4| 4| 1| 7| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Pheochromocytoma Malignant           |       X                                                                  |             
      Pheochromocytoma Benign              |                                                                          |             
      Pheochromocytoma Benign, Multiple    |                                              X                           |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  M   |             
      Pars Distalis, Adenoma               |    X                          X                 X     X  X     X  X      |             
      Pars Distalis, Leukemia Mononuclear  |          X                                                               |             
      Pars Distalis, Lymphoma Malignant    |                                                                          |             
          Lymphocytic                      |                                  X                                       |             
      Pars Intermedia, Lymphoma Malignant  |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Pars Nervosa, Lymphoma Malignant     |                                                                          |             
          Lymphocytic                      |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      C-Cell, Adenoma                      |                                                                          |             
      C-Cell, Carcinoma                    | X                                                                        |             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Mesothelioma Malignant               |                                                                   X      |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |          +                       +                             +     +   |             
      Adenoma                              |                                  X                                       |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Mesothelioma Malignant               |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  49                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 5| 4| 1| 7| 7| 4| 1| 7| 6| 4| 1| 4| 7| 7| 7| 7| 6| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 2| 2| 1| 9| 6| 8| 2| 2| 6| 9| 2| 5| 6| 9| 6| 2| 2| 2| 2| 5| 9| 2| 7| 6| 6|             
                                           | 7| 7| 7| 0| 5| 9| 7| 4| 5| 1| 9| 6| 5| 1| 3| 9| 9| 4| 4| 4| 1| 7| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Interstitial Cell, Adenoma           | X  X  X  X        X  X        X  X           X  X  X  X        X  X  X   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |          +                                                               |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +        +  M        +  +           +  +  +  +  +     +  +  +   |             
      Lumbar, Leukemia Mononuclear         |                                                                          |             
      Lumbar, Lymphoma Malignant           |                                                                          |             
          Lymphocytic                      |                                  X                                       |             
      Mediastinal, Leukemia Mononuclear    |          X                                                        X      |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Lymphocytic                      |                                  X                                       |             
      Mediastinal, Sarcoma, Metastatic,    |                                                                          |             
           Uncertain Primary Site          |                                                       X                  |             
      Pancreatic, Leukemia Mononuclear     |                                                                          |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
          Lymphocytic                      |                                  X                                       |             
      Renal, Leukemia Mononuclear          |          X                                                           X   |             
      Renal, Lymphoma Malignant Lymphocytic|                                  X                                       |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  +        +  M        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |       +  +                    +  +              +        +        +      |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                     X  X  X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
                                            __________________________________________________________________________|             
   Thymus                                  |                   +              +                                       |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Mediastinum, Basosquamous Tumor NOS  |                   X                                                      |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +     +                                               +               |             
      Fibroadenoma                         |          X                                                               |             
                                            __________________________________________________________________________|             
   Skin                                    |    +     +                                                     +         |             
      Basal Cell Carcinoma                 |                                                                          |             
      Squamous Cell Papilloma              |    X                                                                     |             
      Subcutaneous Tissue, Fibroma         |                                                                X         |             
      Subcutaneous Tissue, Fibrosarcoma    |                                                                          |             
      Subcutaneous Tissue, Lipoma          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  50                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 5| 4| 1| 7| 7| 4| 1| 7| 6| 4| 1| 4| 7| 7| 7| 7| 6| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 2| 2| 1| 9| 6| 8| 2| 2| 6| 9| 2| 5| 6| 9| 6| 2| 2| 2| 2| 5| 9| 2| 7| 6| 6|             
                                           | 7| 7| 7| 0| 5| 9| 7| 4| 5| 1| 9| 6| 5| 1| 3| 9| 9| 4| 4| 4| 1| 7| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |          +                                               +               |             
      Osteoma                              |                                                          X               |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Sarcoma                              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Choroid Plexus, Lymphoma Malignant   |                                                                          |             
          Lymphocytic                      |                                                                          |             
      Choroid Plexus, Sarcoma, Metastatic, |                                                                          |             
           Uncertain Primary Site          |                                                       X                  |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Alveolar/Bronchiolar Adenoma         |                                              X                           |             
      Carcinoma, Metastatic, Thyroid Gland | X                                                                        |             
      Leukemia Mononuclear                 |          X                                                     X  X  X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Osteosarcoma, Metastatic, Bone       |                                                                          |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic, Adrenal Gland        |       X                                                                  |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                       X                  |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +           +  +        +              +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                   +      |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Leukemia Mononuclear                 |          X                                                           X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Sarcoma, Metastatic, Uncertain       |                                                                          |             
          Primary Site                     |                                                       X                  |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
      Lymphoma Malignant Lymphocytic       |                                                                          |             
      Mesothelioma Malignant               |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +        +  +        +  +           +  +  +  +  +     +  +  +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  51                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 5| 4| 1| 7| 7| 4| 1| 7| 6| 4| 1| 4| 7| 7| 7| 7| 6| 1| 7| 6| 6| 4|             
                             DAY ON TEST   | 2| 2| 1| 9| 6| 8| 2| 2| 6| 9| 2| 5| 6| 9| 6| 2| 2| 2| 2| 5| 9| 2| 7| 6| 6|             
                                           | 7| 7| 7| 0| 5| 9| 7| 4| 5| 1| 9| 6| 5| 1| 3| 9| 9| 4| 4| 4| 1| 7| 4| 4| 5|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Leukemia Mononuclear                 |          X                                                     X  X  X   |             
      Lymphoma Malignant Lymphocytic       |                                  X                                       |             
      Mesothelioma Malignant               |                                                                   X      |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  52                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 6| 6| 4| 7| 7| 6| 5| 4| 7| 7| 7| 7| 5| 1| 1| 7| 6| 4|              |            |
                             DAY ON TEST   | 1| 8| 5| 4| 6| 2| 2| 3| 7| 6| 2| 2| 2| 2| 1| 8| 8| 2| 2| 6|              |            |
                                           | 7| 9| 4| 0| 5| 9| 9| 6| 5| 5| 9| 9| 9| 0| 9| 9| 9| 4| 0| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          2 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  48        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  47        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          2 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  48        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Hepatocellular Adenoma               |                                                                          |          3 |
      Leukemia Mononuclear                 |          X        X  X                 X                                 |         16 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Mesothelioma Malignant               |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                      +           +                                       |   7        |
      Leukemia Mononuclear                 |                      X                                                   |          2 |
      Mesothelioma Malignant               |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X           X                                                   |          3 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Mesothelioma Malignant               |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |          +           +  +                 +           +                  |  16        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  45        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X           X                                                   |          6 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  53                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 6| 6| 4| 7| 7| 6| 5| 4| 7| 7| 7| 7| 5| 1| 1| 7| 6| 4|              |            |
                             DAY ON TEST   | 1| 8| 5| 4| 6| 2| 2| 3| 7| 6| 2| 2| 2| 2| 1| 8| 8| 2| 2| 6|              |            |
                                           | 7| 9| 4| 0| 5| 9| 9| 6| 5| 5| 9| 9| 9| 0| 9| 9| 9| 4| 0| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Schwannoma Benign                    |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X           X                                                   |          7 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X           X                                                   |          5 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Pheochromocytoma Malignant           |                                                                          |          1 |
      Pheochromocytoma Benign              |    X                    X        X     X           X                     |          8 |
      Pheochromocytoma Benign, Multiple    | X                                                                        |          4 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |    +  +  +     +  +  +  +        +  +  +  +        +  +                  |  47        |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  M  +  +     M  +  +  +     +  +  +  M  M        +  +                  |  43        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +     +  +  +  +     +  M  +  +  +        +  +                  |  46        |
      Pars Distalis, Adenoma               |    X                                      X        X                     |         14 |
      Pars Distalis, Leukemia Mononuclear  |          X           X                                                   |          6 |
      Pars Distalis, Lymphoma Malignant    |                                                                          |            |
          Lymphocytic                      |       X                                                                  |          3 |
      Pars Intermedia, Lymphoma Malignant  |                                                                          |            |
          Lymphocytic                      |                                                                          |          1 |
      Pars Nervosa, Lymphoma Malignant     |                                                                          |            |
          Lymphocytic                      |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      C-Cell, Adenoma                      | X     X        X                                                         |          4 |
      C-Cell, Carcinoma                    |                                                                          |          1 |
      Follicular Cell, Adenoma             |                                  X                                       |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Coagulating Gland                       |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Lymphoma Malignant Lymphocytic       |                                                                          |          1 |
      Mesothelioma Malignant               |                      X                                                   |          4 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  54                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 6| 6| 4| 7| 7| 6| 5| 4| 7| 7| 7| 7| 5| 1| 1| 7| 6| 4|              |            |
                             DAY ON TEST   | 1| 8| 5| 4| 6| 2| 2| 3| 7| 6| 2| 2| 2| 2| 1| 8| 8| 2| 2| 6|              |            |
                                           | 7| 9| 4| 0| 5| 9| 9| 6| 5| 5| 9| 9| 9| 0| 9| 9| 9| 4| 0| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |          +           +  +                 +           +                  |  13        |
      Adenoma                              |                                                                          |          2 |
      Carcinoma                            |                                                       X                  |          1 |
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
      Lymphoma Malignant Lymphocytic       |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
      Mesothelioma Malignant               |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Mesothelioma Malignant               |                      X                                                   |          4 |
      Interstitial Cell, Adenoma           | X  X  X  X     X  X  X  X     X  X  X  X           X  X                  |         44 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |          +           +  +                 +           +                  |  11        |
      Leukemia Mononuclear                 |          X           X                                                   |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  49        |
      Lumbar, Leukemia Mononuclear         |          X                                                               |          1 |
      Lumbar, Lymphoma Malignant           |                                                                          |            |
          Lymphocytic                      |       X                                                                  |          2 |
      Mediastinal, Leukemia Mononuclear    |          X           X                                                   |          6 |
      Mediastinal, Lymphoma Malignant      |                                                                          |            |
          Lymphocytic                      |       X                                                                  |          2 |
      Mediastinal, Sarcoma, Metastatic,    |                                                                          |            |
           Uncertain Primary Site          |                                                                          |          1 |
      Pancreatic, Leukemia Mononuclear     |          X           X                                                   |          4 |
      Pancreatic, Lymphoma Malignant       |                                                                          |            |
          Lymphocytic                      |                                                                          |          2 |
      Renal, Leukemia Mononuclear          |          X           X                                                   |          4 |
      Renal, Lymphoma Malignant Lymphocytic|       X                                                                  |          3 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  46        |
      Leukemia Mononuclear                 |          X           X                                                   |          5 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  M  +  +              +                             +                  |  22        |
      Leukemia Mononuclear                 |          X                                                               |          4 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X        X  X                 X                                 |         15 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |       +  +           +  +                 +           M                  |  14        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  55                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 6| 6| 4| 7| 7| 6| 5| 4| 7| 7| 7| 7| 5| 1| 1| 7| 6| 4|              |            |
                             DAY ON TEST   | 1| 8| 5| 4| 6| 2| 2| 3| 7| 6| 2| 2| 2| 2| 1| 8| 8| 2| 2| 6|              |            |
                                           | 7| 9| 4| 0| 5| 9| 9| 6| 5| 5| 9| 9| 9| 0| 9| 9| 9| 4| 0| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |                      X                                                   |          2 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Mediastinum, Basosquamous Tumor NOS  |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |    +     +           +  M        +        +           +                  |  13        |
      Fibroadenoma                         |    X                             X                                       |          5 |
                                            __________________________________________________________________________|____________|
   Skin                                    | +        +     +     +  +           +     +        +  +                  |  20        |
      Basal Cell Carcinoma                 |                X                                                         |          1 |
      Squamous Cell Papilloma              |                                     X                                    |          2 |
      Subcutaneous Tissue, Fibroma         | X                                                                        |          2 |
      Subcutaneous Tissue, Fibrosarcoma    |                                                                          |          1 |
      Subcutaneous Tissue, Lipoma          |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |          +           +  +                 +           +                  |  10        |
      Osteoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   1        |
      Sarcoma                              |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |                      X                                                   |          3 |
      Choroid Plexus, Lymphoma Malignant   |                                                                          |            |
          Lymphocytic                      |       X                                                                  |          1 |
      Choroid Plexus, Sarcoma, Metastatic, |                                                                          |            |
           Uncertain Primary Site          |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          2 |
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |          1 |
      Leukemia Mononuclear                 |          X           X                 X                                 |         14 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Osteosarcoma, Metastatic, Bone       |                                           X                              |          1 |
      Pheochromocytoma Malignant,          |                                                                          |            |
          Metastatic, Adrenal Gland        |                                                                          |          1 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  56                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 6| 6| 6| 4| 7| 7| 6| 5| 4| 7| 7| 7| 7| 5| 1| 1| 7| 6| 4|              |            |
                             DAY ON TEST   | 1| 8| 5| 4| 6| 2| 2| 3| 7| 6| 2| 2| 2| 2| 1| 8| 8| 2| 2| 6|              |            |
                                           | 7| 9| 4| 0| 5| 9| 9| 6| 5| 5| 9| 9| 9| 0| 9| 9| 9| 4| 0| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|              |     A      |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|              |     L      |
    UM                                     | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +        +  +  +     +  +  +  +  +        +  +                  |  44        |
      Leukemia Mononuclear                 |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |    I  +              +                    I                              |   2        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X           X                                                   |          8 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Sarcoma, Metastatic, Uncertain       |                                                                          |            |
          Primary Site                     |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          1 |
      Mesothelioma Malignant               |                                                                          |          2 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +     +  +  +  +     +  +  +  +  +        +  +                  |  50        |
      Leukemia Mononuclear                 |          X        X  X                 X                                 |         16 |
      Lymphoma Malignant Lymphocytic       |       X                                                                  |          3 |
      Mesothelioma Malignant               |                      X                                                   |          4 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  57                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 4| 1| 1| 7| 7| 7| 6| 4| 7| 6| 6| 6| 4| 6| 5| 5| 4| 1| 7| 6| 5| 1| 1|             
                             DAY ON TEST   | 2| 6| 6| 8| 8| 3| 2| 2| 5| 6| 3| 9| 8| 4| 6| 1| 9| 5| 6| 8| 2| 1| 6| 8| 8|             
                                           | 7| 5| 3| 9| 9| 0| 9| 7| 4| 5| 0| 5| 5| 3| 5| 8| 9| 6| 5| 9| 9| 8| 2| 9| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |                                        +     +  +  +           +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                                        +     +  +  +           +  +      |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                                        +     +  +  +           +  A      |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                        +     +  +  +           +  +      |             
      Mesothelioma Malignant               |                                                 X                        |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                        +     +  +  +           +  A      |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +              +  +  +  A     +  +  +  +     +  +  M        +  +  A      |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +              +  +  +  A     +  +  +  +     +  +  +        +  M  +      |             
      Leukemia Mononuclear                 |                                                    X              X      |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +              +  +  +  A     +  +  +  +     +  +  M        +  +  A      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Hepatocellular Carcinoma             |                                                                          |             
      Hepatocellular Adenoma               |                                                                          |             
      Leukemia Mononuclear                 |                         X           X        X  X  X           X  X      |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
      Neoplastic Nodule                    |                                                                          |             
      Neoplastic Nodule, Multiple          |                               X                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                 +           +            |             
      Leukemia Mononuclear                 |                                                                          |             
      Mesothelioma Malignant               |                                                 X           X            |             
                                            __________________________________________________________________________|             
   Pancreas                                | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Adenoma                              |                                                             X            |             
      Leukemia Mononuclear                 |                         X                                      X         |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                        +     +  +  +           +  +      |             
                                            __________________________________________________________________________|             
   Stomach                                 | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
                                            __________________________________________________________________________|             
   Tongue                                  | +              +  +  +  +     +  +  +  +     +  +  +        M  +  +      |             
      Leukemia Mononuclear                 |                         X              X                                 |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |                                        +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                                                                X  X      |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  58                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 4| 1| 1| 7| 7| 7| 6| 4| 7| 6| 6| 6| 4| 6| 5| 5| 4| 1| 7| 6| 5| 1| 1|             
                             DAY ON TEST   | 2| 6| 6| 8| 8| 3| 2| 2| 5| 6| 3| 9| 8| 4| 6| 1| 9| 5| 6| 8| 2| 1| 6| 8| 8|             
                                           | 7| 5| 3| 9| 9| 0| 9| 7| 4| 5| 0| 5| 5| 3| 5| 8| 9| 6| 5| 9| 9| 8| 2| 9| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                                        +     +  +  +           +  +      |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |                                        +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |                                        +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
      Pheochromocytoma Benign              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |                                        +     +  +  +           +  +      |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +              +  M  +  +     +  +  +  +     M  +  +        +  +  +      |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Pars Distalis, Adenoma               |                      X  X     X  X           X  X                        |             
      Pars Distalis, Adenoma, Multiple     |                                        X                                 |             
      Pars Distalis, Leukemia Mononuclear  |                                     X                          X         |             
      Pars Distalis, Lymphoma Malignant    |                                                                          |             
          Undifferentiated Cell Type       |                                                                          |             
      Pars Intermedia, Leukemia Mononuclear|                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |                         +              +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                         X                                                |             
      C-Cell, Adenoma                      |                                                                          |             
      C-Cell, Carcinoma                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Basosquamous Tumor Benign            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |                                        +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
      Mesothelioma Malignant               |                                                 X           X            |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |                         +        +  +  +     +  +  +        +  +  +      |             
      Adenoma                              |                                     X  X     X              X            |             
      Squamous Cell Carcinoma              |                                        X                                 |             
                                            __________________________________________________________________________|             
   Prostate                                |                                  +     +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                      +              +  +     +  +  +           +  +      |             
      Mesothelioma Malignant               |                                                 X                        |             
                                            __________________________________________________________________________|             
   Testes                                  | +              +  +  +        +     +  +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  59                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 4| 1| 1| 7| 7| 7| 6| 4| 7| 6| 6| 6| 4| 6| 5| 5| 4| 1| 7| 6| 5| 1| 1|             
                             DAY ON TEST   | 2| 6| 6| 8| 8| 3| 2| 2| 5| 6| 3| 9| 8| 4| 6| 1| 9| 5| 6| 8| 2| 1| 6| 8| 8|             
                                           | 7| 5| 3| 9| 9| 0| 9| 7| 4| 5| 0| 5| 5| 3| 5| 8| 9| 6| 5| 9| 9| 8| 2| 9| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                 X           X            |             
      Interstitial Cell, Adenoma           | X              X  X  X        X     X  X        X           X  X  X      |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                        +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
      Sternal, Lymphoma Malignant          |                                                                          |             
          Undifferentiated Cell Type       |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |                         +           +  +     +  +  +        +  +  +      |             
      Lumbar, Leukemia Mononuclear         |                                                                          |             
      Lumbar, Lymphoma Malignant Mixed     |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Undifferentiated Cell Type       |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                     X                                    |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
          Undifferentiated Cell Type       |                                                                          |             
      Renal, Leukemia Mononuclear          |                                                                X         |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |                         +              +     +  +  +        +  +  +      |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Leukemia Mononuclear                 |                         X                                      X         |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                         +              M     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                         X                                      X  X      |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |                      +  +           +  +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                         X           X        X     X           X  X      |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                        +     +  M  +           M  +      |             
      Leukemia Mononuclear                 |                                                                   X      |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |                                        +     +  M  +           +  +      |             
      Fibroadenoma                         |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |                                              +  +  +        +  +  +      |             
      Subcutaneous Tissue, Fibroma         |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  60                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 4| 1| 1| 7| 7| 7| 6| 4| 7| 6| 6| 6| 4| 6| 5| 5| 4| 1| 7| 6| 5| 1| 1|             
                             DAY ON TEST   | 2| 6| 6| 8| 8| 3| 2| 2| 5| 6| 3| 9| 8| 4| 6| 1| 9| 5| 6| 8| 2| 1| 6| 8| 8|             
                                           | 7| 5| 3| 9| 9| 0| 9| 7| 4| 5| 0| 5| 5| 3| 5| 8| 9| 6| 5| 9| 9| 8| 2| 9| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                        +     +  +  +           +  +      |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                 +                        |             
      Mesothelioma Malignant               |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |                         +              +     +  +  +           +  +      |             
      Leukemia Mononuclear                 |                         X                                      X         |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
      Meningioma Benign                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |                   +     +           +  +     +  +  +        +  +  +      |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Leukemia Mononuclear                 |                         X           X           X  X           X  X      |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                                                                X         |             
      Glands, Carcinoma                    |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                        +     +  +  +           +  +      |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                         X           X              X           X  X      |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                                                                          |             
      Serosa, Mesothelioma Malignant       |                                                 X                        |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +              +  +  +  +     +  +  +  +     +  +  +        +  +  +      |             
      Leukemia Mononuclear                 |                         X           X  X     X  X  X           X  X      |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  61                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 4| 4| 1| 1| 7| 7| 7| 6| 4| 7| 6| 6| 6| 4| 6| 5| 5| 4| 1| 7| 6| 5| 1| 1|             
                             DAY ON TEST   | 2| 6| 6| 8| 8| 3| 2| 2| 5| 6| 3| 9| 8| 4| 6| 1| 9| 5| 6| 8| 2| 1| 6| 8| 8|             
                                           | 7| 5| 3| 9| 9| 0| 9| 7| 4| 5| 0| 5| 5| 3| 5| 8| 9| 6| 5| 9| 9| 8| 2| 9| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|             
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Malignant               |                                                 X           X            |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  62                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 1| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 5| 4| 7| 7| 1| 5| 1| 7| 7| 1| 5| 4|             
                             DAY ON TEST   | 3| 9| 3| 2| 6| 2| 2| 2| 2| 2| 2| 0| 2| 4| 5| 3| 2| 9| 0| 9| 3| 3| 9| 8| 6|             
                                           | 0| 1| 0| 9| 3| 9| 9| 7| 7| 4| 8| 4| 0| 6| 8| 0| 3| 1| 9| 1| 0| 0| 1| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    0.1% LM                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |                                     +  +  +           +              +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         |                +                    +  +  +           A              +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |                +                    +  +  +           A              +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                +                    +  +  +           A              +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                +                    +  +  +           A              +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     A     +  +     +   |             
      Leukemia Mononuclear                 |                                        X                                 |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +     +  +     +  +  +  +  +  A  +  +  +  +  +  +     A     +  +     +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Hepatocellular Carcinoma             |                                              X                           |             
      Hepatocellular Adenoma               | X                                                                        |             
      Leukemia Mononuclear                 | X                                X     X        X                    X   |             
      Lymphoma Malignant Mixed             |                            X                                             |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
      Neoplastic Nodule                    |                               X                                          |             
      Neoplastic Nodule, Multiple          |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               | +                                                     +              +   |             
      Leukemia Mononuclear                 | X                                                                    X   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Adenoma                              |                                                                          |             
      Leukemia Mononuclear                 |                                  X     X                                 |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                            +        +  +  +           +              +   |             
                                            __________________________________________________________________________|             
   Stomach                                 | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +     +  +     M  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
                                            __________________________________________________________________________|             
   Tongue                                  | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     M   |             
      Leukemia Mononuclear                 |                                  X                                       |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |          +     +              +  +  +  +  +  +        +              +   |             
      Leukemia Mononuclear                 |                                  X     X                                 |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  63                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 1| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 5| 4| 7| 7| 1| 5| 1| 7| 7| 1| 5| 4|             
                             DAY ON TEST   | 3| 9| 3| 2| 6| 2| 2| 2| 2| 2| 2| 0| 2| 4| 5| 3| 2| 9| 0| 9| 3| 3| 9| 8| 6|             
                                           | 0| 1| 0| 9| 3| 9| 9| 7| 7| 4| 8| 4| 0| 6| 8| 0| 3| 1| 9| 1| 0| 0| 1| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    0.1% LM                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |                               +     +  +  +           +              +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |                               +     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                        X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |                               +     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                        X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
      Pheochromocytoma Benign              |                                     X                                    |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +                                +  +  +  +           +              +   |             
      Adenoma                              | X                                X                                       |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +     +  +     M  +  +  +  +  +  +  +  +  +  +  +     M     +  +     +   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +     I  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Pars Distalis, Adenoma               | X                 X        X  X        X                    X  X         |             
      Pars Distalis, Adenoma, Multiple     |          X                          X                                    |             
      Pars Distalis, Leukemia Mononuclear  | X                                X     X        X                    X   |             
      Pars Distalis, Lymphoma Malignant    |                                                                          |             
          Undifferentiated Cell Type       |                                           X                              |             
      Pars Intermedia, Leukemia Mononuclear|                                        X                                 |             
      Pars Nervosa, Leukemia Mononuclear   |                                        X                                 |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |       +                       +     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
      C-Cell, Adenoma                      |       X                                                                  |             
      C-Cell, Carcinoma                    |                                                       X                  |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Tissue NOS                              |                                                                          |             
      Basosquamous Tumor Benign            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                           +                              |             
                                            __________________________________________________________________________|             
   Epididymis                              |                                     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |       +  +              +        +  +  +  M           +     +        +   |             
      Adenoma                              |                                  X                                       |             
      Squamous Cell Carcinoma              |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                | +                                   +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |          +           +     +        +  +  +           +     +        +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |       +  +     +     +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Leukemia Mononuclear                 |                                        X        X                        |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  64                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 1| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 5| 4| 7| 7| 1| 5| 1| 7| 7| 1| 5| 4|             
                             DAY ON TEST   | 3| 9| 3| 2| 6| 2| 2| 2| 2| 2| 2| 0| 2| 4| 5| 3| 2| 9| 0| 9| 3| 3| 9| 8| 6|             
                                           | 0| 1| 0| 9| 3| 9| 9| 7| 7| 4| 8| 4| 0| 6| 8| 0| 3| 1| 9| 1| 0| 0| 1| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    0.1% LM                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
      Interstitial Cell, Adenoma           |       X  X     X     X  X  X  X  X  X  X     X  X     X     X  X     X   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                        X                                 |             
      Sternal, Lymphoma Malignant          |                                                                          |             
          Undifferentiated Cell Type       |                                           X                              |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +     +  +           +     +  +  +  +  +  +     +     +              +   |             
      Lumbar, Leukemia Mononuclear         | X                                                                        |             
      Lumbar, Lymphoma Malignant Mixed     |                            X                                             |             
      Mediastinal, Leukemia Mononuclear    |                                  X     X        X                    X   |             
      Mediastinal, Lymphoma Malignant      |                                                                          |             
          Undifferentiated Cell Type       |                                           X                              |             
      Pancreatic, Leukemia Mononuclear     |                                        X                                 |             
      Pancreatic, Lymphoma Malignant       |                                                                          |             
          Undifferentiated Cell Type       |                                           X                              |             
      Renal, Leukemia Mononuclear          | X                                                                        |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |                      +              +  +  +           +              +   |             
      Carcinoma, Metastatic, Thyroid Gland |                                                       X                  |             
      Leukemia Mononuclear                 |                                        X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |                                     +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                        X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Spleen                                  | +                          +     +  +  +  +     +     +              +   |             
      Leukemia Mononuclear                 | X                                X     X        X                    X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Thymus                                  |                                  +  +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                  X     X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +                             +     M  +  +           M              M   |             
      Fibroadenoma                         |                               X                                          |             
      Leukemia Mononuclear                 | X                                                                        |             
                                            __________________________________________________________________________|             
   Skin                                    |                                  +  +  +  +  +        +        +     +   |             
      Subcutaneous Tissue, Fibroma         |                                  X                                       |             
      Subcutaneous Tissue, Sarcoma         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  65                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 1| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 5| 4| 7| 7| 1| 5| 1| 7| 7| 1| 5| 4|             
                             DAY ON TEST   | 3| 9| 3| 2| 6| 2| 2| 2| 2| 2| 2| 0| 2| 4| 5| 3| 2| 9| 0| 9| 3| 3| 9| 8| 6|             
                                           | 0| 1| 0| 9| 3| 9| 9| 7| 7| 4| 8| 4| 0| 6| 8| 0| 3| 1| 9| 1| 0| 0| 1| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    0.1% LM                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                     +  +  +           +              +   |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                           +                              |             
      Mesothelioma Malignant               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +     +                             +  +  +           +              +   |             
      Leukemia Mononuclear                 |                                        X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
      Meningioma Benign                    |       X                                                                  |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |          +              +  +  +  +  +  +  +           +              +   |             
      Carcinoma, Metastatic, Thyroid Gland |                                                       X                  |             
      Leukemia Mononuclear                 |                                  X     X                             X   |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Nose                                    | +     +  +     +  +  +  +  +  +  +  +  +  +     +     +     +  +     +   |             
      Leukemia Mononuclear                 |                                                 X                        |             
      Glands, Carcinoma                    |                                     X                                    |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                     +  +  +           +              +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                         +        +     +                       +     +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Leukemia Mononuclear                 |                                  X     X        X                    X   |             
      Lymphoma Malignant Mixed             |                            X                                             |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +     +  +     M  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Leukemia Mononuclear                 | X                                                                        |             
      Serosa, Mesothelioma Malignant       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +     +  +     +  +  +  +  +  +  +  +  +  +  +  +     +     +  +     +   |             
      Leukemia Mononuclear                 | X                                X     X        X                    X   |             
      Lymphoma Malignant Mixed             |                            X                                             |             
      Lymphoma Malignant Undifferentiated  |                                                                          |             
          Cell Type                        |                                           X                              |             
      Mesothelioma Benign                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  66                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 1| 7| 7| 4| 7| 7| 7| 7| 7| 7| 7| 6| 5| 4| 7| 7| 1| 5| 1| 7| 7| 1| 5| 4|             
                             DAY ON TEST   | 3| 9| 3| 2| 6| 2| 2| 2| 2| 2| 2| 0| 2| 4| 5| 3| 2| 9| 0| 9| 3| 3| 9| 8| 6|             
                                           | 0| 1| 0| 9| 3| 9| 9| 7| 7| 4| 8| 4| 0| 6| 8| 0| 3| 1| 9| 1| 0| 0| 1| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    0.1% LM                                | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  67                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 5| 4| 7| 1| 7| 7| 7| 7| 7| 6| 6| 4| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 2| 2| 7| 6| 2| 9| 3| 2| 2| 2| 2| 7| 7| 6| 3| 2| 2| 1| 6|              |            |
                                           | 0| 9| 0| 2| 3| 1| 1| 0| 7| 4| 9| 7| 8| 1| 3| 0| 9| 9| 6| 5|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|              |     A      |
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |          +                                                               |  12        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |          +                                                               |  12        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |          +                                                               |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |          +                                                               |  12        |
      Mesothelioma Malignant               |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |          +                                                               |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  47        |
      Leukemia Mononuclear                 |          X                                                               |          4 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +     +     +  +  +  +  +  A  +     +  +  +  +                  |  44        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
      Hepatocellular Carcinoma             |                                                                          |          1 |
      Hepatocellular Adenoma               |                                                                          |          1 |
      Leukemia Mononuclear                 |          X     X           X           X              X                  |         17 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
      Neoplastic Nodule                    |                                                                          |          1 |
      Neoplastic Nodule, Multiple          |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                     +                                    |   6        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Mesothelioma Malignant               |                                     X                                    |          3 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
      Adenoma                              |                                  X                                       |          2 |
      Leukemia Mononuclear                 |          X                 X                          X                  |          7 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
      Mesothelioma Malignant               |                                     X                                    |          1 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |          +     +                                                         |  14        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  49        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  48        |
      Leukemia Mononuclear                 |                                                                          |          3 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   |                                     +                                    |  18        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  68                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 5| 4| 7| 1| 7| 7| 7| 7| 7| 6| 6| 4| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 2| 2| 7| 6| 2| 9| 3| 2| 2| 2| 2| 7| 7| 6| 3| 2| 2| 1| 6|              |            |
                                           | 0| 9| 0| 2| 3| 1| 1| 0| 7| 4| 9| 7| 8| 1| 3| 0| 9| 9| 6| 5|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|              |     A      |
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |                                                                          |          4 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           |    +  +  +     +           +     +                                       |  18        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   |    +  +  +     +           +     +                                       |  18        |
      Leukemia Mononuclear                 |          X     X                                                         |          5 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  |    +  +  +     +           +     +                                       |  18        |
      Leukemia Mononuclear                 |          X     X                                                         |          5 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
      Pheochromocytoma Benign              |    X           X                 X                                       |          4 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +        +                                                               |  15        |
      Adenoma                              |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  45        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  49        |
      Pars Distalis, Adenoma               |          X                                                               |         14 |
      Pars Distalis, Adenoma, Multiple     |                                                                          |          3 |
      Pars Distalis, Leukemia Mononuclear  |          X     X           X           X              X                  |         12 |
      Pars Distalis, Lymphoma Malignant    |                                                                          |            |
          Undifferentiated Cell Type       |                                                                          |          1 |
      Pars Intermedia, Leukemia Mononuclear|                                                                          |          1 |
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |          +              +                       +                        |  17        |
      Leukemia Mononuclear                 |                                                                          |          1 |
      C-Cell, Adenoma                      |                                                                          |          1 |
      C-Cell, Carcinoma                    |                         X                                                |          2 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tissue NOS                              |                                              +                           |   1        |
      Basosquamous Tumor Benign            |                                              X                           |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Coagulating Gland                       |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Epididymis                              |          +                                                               |  13        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  69                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 5| 4| 7| 1| 7| 7| 7| 7| 7| 6| 6| 4| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 2| 2| 7| 6| 2| 9| 3| 2| 2| 2| 2| 7| 7| 6| 3| 2| 2| 1| 6|              |            |
                                           | 0| 9| 0| 2| 3| 1| 1| 0| 7| 4| 9| 7| 8| 1| 3| 0| 9| 9| 6| 5|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|              |     A      |
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Mesothelioma Malignant               |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |          +                                      +     +                  |  22        |
      Adenoma                              |                                                                          |          5 |
      Squamous Cell Carcinoma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Prostate                                |          +                                                               |  14        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |       +  +     +                    +        +                           |  22        |
      Mesothelioma Malignant               |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  46        |
      Leukemia Mononuclear                 |                                                                          |          3 |
      Mesothelioma Benign                  |                               X                                          |          1 |
      Mesothelioma Malignant               |                                                                          |          2 |
      Interstitial Cell, Adenoma           | X  X  X  X     X     X  X  X  X  X  X  X     X  X  X  X                  |         43 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |          +                                                               |  12        |
      Leukemia Mononuclear                 |          X                                                               |          3 |
      Sternal, Lymphoma Malignant          |                                                                          |            |
          Undifferentiated Cell Type       |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              |       +  +     +           +        +           +     +                  |  29        |
      Lumbar, Leukemia Mononuclear         |                                                                          |          1 |
      Lumbar, Lymphoma Malignant Mixed     |                                                                          |          1 |
      Mediastinal, Leukemia Mononuclear    |          X                                            X                  |          6 |
      Mediastinal, Lymphoma Malignant      |                                                                          |            |
          Undifferentiated Cell Type       |                                                                          |          1 |
      Pancreatic, Leukemia Mononuclear     |          X     X                                      X                  |          5 |
      Pancreatic, Lymphoma Malignant       |                                                                          |            |
          Undifferentiated Cell Type       |                                                                          |          1 |
      Renal, Leukemia Mononuclear          |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  |          +     +                    +                 +                  |  18        |
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |          1 |
      Leukemia Mononuclear                 |          X                                            X                  |          6 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |          +     +                                      +                  |  14        |
      Leukemia Mononuclear                 |          X                                            X                  |          7 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spleen                                  |          +     +        +  +  +        +              +                  |  25        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  70                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 5| 4| 7| 1| 7| 7| 7| 7| 7| 6| 6| 4| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 2| 2| 7| 6| 2| 9| 3| 2| 2| 2| 2| 7| 7| 6| 3| 2| 2| 1| 6|              |            |
                                           | 0| 9| 0| 2| 3| 1| 1| 0| 7| 4| 9| 7| 8| 1| 3| 0| 9| 9| 6| 5|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|              |     A      |
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |          X     X           X           X              X                  |         16 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |       M  +                                                               |  11        |
      Leukemia Mononuclear                 |          X                                                               |          5 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |          +                                                               |  10        |
      Fibroadenoma                         |                                                                          |          1 |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Skin                                    |       +  +                 +     +                                       |  18        |
      Subcutaneous Tissue, Fibroma         |                                                                          |          1 |
      Subcutaneous Tissue, Sarcoma         |       X                                                                  |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |          +                                                               |  12        |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   2        |
      Mesothelioma Malignant               |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |          +                                                               |  15        |
      Leukemia Mononuclear                 |          X                                                               |          5 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
      Meningioma Benign                    |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    |          +     +     +              +  +     +  +     +                  |  28        |
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |          1 |
      Leukemia Mononuclear                 |          X     X                       X              X                  |         13 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +     +     +  +  +  +  +  +  +        +  +  +                  |  48        |
      Leukemia Mononuclear                 |          X                             X              X                  |          5 |
      Glands, Carcinoma                    |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 |          +                                                               |  12        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  71                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 7| 5| 4| 7| 1| 7| 7| 7| 7| 7| 6| 6| 4| 7| 7| 7| 7| 4|              |            |
                             DAY ON TEST   | 3| 2| 2| 7| 6| 2| 9| 3| 2| 2| 2| 2| 7| 7| 6| 3| 2| 2| 1| 6|              |            |
                                           | 0| 9| 0| 2| 3| 1| 1| 0| 7| 4| 9| 7| 8| 1| 3| 0| 9| 9| 6| 5|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|              |     A      |
    0.1% LM                                | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 SPECIAL SENSES SYSTEM - cont              |                                                                          |            |
                                           |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |       +  +                    +        +              I                  |   9        |
      Leukemia Mononuclear                 |          X                                                               |          1 |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |          X                                            X                  |         11 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  49        |
      Leukemia Mononuclear                 |                                                                          |          1 |
      Serosa, Mesothelioma Malignant       |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +     +     +  +  +  +  +  +  +     +  +  +  +                  |  50        |
      Leukemia Mononuclear                 |          X     X           X           X              X                  |         18 |
      Lymphoma Malignant Mixed             |                                                                          |          1 |
      Lymphoma Malignant Undifferentiated  |                                                                          |            |
          Cell Type                        |                                                                          |          1 |
      Mesothelioma Benign                  |                               X                                          |          1 |
      Mesothelioma Malignant               |                                     X                                    |          3 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  72                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 5| 1| 1| 5| 4| 4| 1| 1| 7| 7| 6| 4| 1| 7| 7| 7| 6| 4| 1| 7| 1| 6| 7|             
                             DAY ON TEST   | 2| 8| 5| 8| 8| 5| 6| 6| 8| 8| 2| 2| 8| 6| 8| 2| 2| 2| 7| 6| 9| 2| 9| 7| 2|             
                                           | 7| 7| 5| 9| 9| 5| 3| 3| 9| 9| 8| 7| 0| 3| 9| 9| 4| 4| 4| 5| 1| 8| 1| 4| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |       +        M                                                         |             
                                            __________________________________________________________________________|             
   Intestine Large                         |       +        +                                                         |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |       +        +                                                         |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |       +        +                                                         |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |       +        +                                                         |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | M  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Cholangiocarcinoma                   |                                                                          |             
      Hemangiosarcoma                      |                                                                          |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Leukemia Mononuclear                 | X              X              X              X     X  X              X  X|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Neoplastic Nodule                    |                                              X                           |             
      Neoplastic Nodule, Multiple          |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                       +                  |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Mesothelioma Malignant               |                                                       X                  |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Adenoma                              |                                                                          |             
      Leukemia Mononuclear                 |                                              X        X              X  X|             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |       +        +                                                         |             
      Sublingual Gland, Lymphoma Malignant |                                                                          |             
          Mixed                            |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |    +                                                                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  73                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 5| 1| 1| 5| 4| 4| 1| 1| 7| 7| 6| 4| 1| 7| 7| 7| 6| 4| 1| 7| 1| 6| 7|             
                             DAY ON TEST   | 2| 8| 5| 8| 8| 5| 6| 6| 8| 8| 2| 2| 8| 6| 8| 2| 2| 2| 7| 6| 9| 2| 9| 7| 2|             
                                           | 7| 7| 5| 9| 9| 5| 3| 3| 9| 9| 8| 7| 0| 3| 9| 9| 4| 4| 4| 5| 1| 8| 1| 4| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |       +        +                                                        +|             
      Leukemia Mononuclear                 |                X                                                         |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Schwannoma Malignant                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |       +        +                                                         |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |       +        +                                                         |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |       +        +                                                         |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |       X                                                                  |             
      Pheochromocytoma Benign, Multiple    |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |       +        +                                                         |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  M        M              +  +  +        +  +  +  +        +     +  +|             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Pars Distalis, Adenoma               | X  X                                X           X                        |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
      Pars Distalis, Leukemia Mononuclear  |                                              X        X              X  X|             
      Pars Distalis, Pars Intermedia, Pars |                                                                          |             
          Nervosa, Leukemia Mononuclear    |                                                                          |             
      Pars Distalis, Pars Nervosa,         |                                                                          |             
          Leukemia Mononuclear             |                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +        +                    +                          +         |             
      C-Cell, Adenoma                      |                                                                X         |             
      C-Cell, Carcinoma                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |       +        +                                      +                  |             
      Mesothelioma Malignant               |                                                       X                  |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |       +        +              +                                +         |             
      Adenoma                              |                                                                          |             
      Carcinoma                            |                               X                                          |             
                                            __________________________________________________________________________|             
   Prostate                                |       +        +                                                         |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  74                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 5| 1| 1| 5| 4| 4| 1| 1| 7| 7| 6| 4| 1| 7| 7| 7| 6| 4| 1| 7| 1| 6| 7|             
                             DAY ON TEST   | 2| 8| 5| 8| 8| 5| 6| 6| 8| 8| 2| 2| 8| 6| 8| 2| 2| 2| 7| 6| 9| 2| 9| 7| 2|             
                                           | 7| 7| 5| 9| 9| 5| 3| 3| 9| 9| 8| 7| 0| 3| 9| 9| 4| 4| 4| 5| 1| 8| 1| 4| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +     +        +                 +           +  +                    +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                       X                  |             
      Interstitial Cell, Adenoma           | X     X        X              X  X  X        X  X  X  X        X     X  X|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |       +        +                                                         |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +        +                                      +        +     +  +|             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                         X|             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                       X              X   |             
      Renal, Leukemia Mononuclear          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |       +        +                                                         |             
      Leukemia Mononuclear                 |                X                                                         |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +        +                                                     +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +        +              +  +           +  +  +  +        +     +   |             
      Hemangioma                           |                                                       X                  |             
      Hemangiosarcoma                      |                                                                          |             
      Leukemia Mononuclear                 |                X                             X     X  X              X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Sarcoma                              |                                  X                                       |             
                                            __________________________________________________________________________|             
   Thymus                                  |       +        +                                                         |             
      Leukemia Mononuclear                 |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |       +        +                                                         |             
      Fibroadenoma                         |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |       +        +                    +                 +                 +|             
      Basosquamous Tumor Benign            |                                                                          |             
      Keratoacanthoma                      |                                                                          |             
      Squamous Cell Papilloma              |                                                                         X|             
      Subcutaneous Tissue, Fibroma         |       X                                                                  |             
      Subcutaneous Tissue, Lymphoma        |                                                                          |             
          Malignant Mixed                  |                                                                          |             
      Subcutaneous Tissue, Myxoma          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  75                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 5| 1| 1| 5| 4| 4| 1| 1| 7| 7| 6| 4| 1| 7| 7| 7| 6| 4| 1| 7| 1| 6| 7|             
                             DAY ON TEST   | 2| 8| 5| 8| 8| 5| 6| 6| 8| 8| 2| 2| 8| 6| 8| 2| 2| 2| 7| 6| 9| 2| 9| 7| 2|             
                                           | 7| 7| 5| 9| 9| 5| 3| 3| 9| 9| 8| 7| 0| 3| 9| 9| 4| 4| 4| 5| 1| 8| 1| 4| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |                                     X                                    |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |       +        +                                               +         |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |       +        +                                                         |             
      Leukemia Mononuclear                 |                X                                                         |             
      Choroid Plexus, Lymphoma Malignant   |                                                                          |             
          Mixed                            |                                                                          |             
                                            __________________________________________________________________________|             
   Peripheral Nerve                        |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +        +              +                       +              +   |             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |                                                                          |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Cholangiocarcinoma, Metastatic, Liver|                                                                          |             
      Leukemia Mononuclear                 |                X                                      X              X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Mediastinum, Schwannoma Malignant,   |                                                                          |             
           Metastatic, Heart               |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +        +              +  +  +        +  +  +  +        +     +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
                                            __________________________________________________________________________|             
   Trachea                                 |       +        +                                                         |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +  +                       +  I                                       |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                              X                       X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +        +              +  +  +        +  +  +  +        +     +  +|             
      Leukemia Mononuclear                 | X              X              X              X     X  X              X  X|             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  76                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 6| 5| 1| 1| 5| 4| 4| 1| 1| 7| 7| 6| 4| 1| 7| 7| 7| 6| 4| 1| 7| 1| 6| 7|             
                             DAY ON TEST   | 2| 8| 5| 8| 8| 5| 6| 6| 8| 8| 2| 2| 8| 6| 8| 2| 2| 2| 7| 6| 9| 2| 9| 7| 2|             
                                           | 7| 7| 5| 9| 9| 5| 3| 3| 9| 9| 8| 7| 0| 3| 9| 9| 4| 4| 4| 5| 1| 8| 1| 4| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                       X                  |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  77                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 6| 6| 7| 6| 7| 7| 5| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 9| 2| 2| 2| 6| 2| 2| 2| 6| 6| 0| 0| 9| 4| 0| 2| 7| 2| 0| 7| 2| 2| 9| 2| 6|             
                                           | 1| 9| 8| 4| 5| 9| 7| 4| 5| 3| 4| 4| 0| 3| 8| 9| 3| 9| 3| 4| 9| 9| 9| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |                                        +  +              +           +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         |       +                                +  A              +           +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |       +                                +  A              +           +   |             
      Leukemia Mononuclear                 |       X                                                                  |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |                                        +  A              +           +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |                                        +  A              +           +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +     +  +  +        +  +  +  +  A  +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +     +  +  +        +  +  +  +  A  +  +  +  +  +  +  +  +  +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +     +  +  +        +  +  +  +  A  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |       X                             X                                    |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    M  +  +     M  +  +        M  +  +  +  A  M  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |       X                                                                  |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Cholangiocarcinoma                   |                               X                                          |             
      Hemangiosarcoma                      |    X                                                                     |             
      Hepatocellular Adenoma, Multiple     |                                                                          |             
      Leukemia Mononuclear                 |       X  X                       X  X        X        X        X     X   |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Neoplastic Nodule                    |                                                                          |             
      Neoplastic Nodule, Multiple          |                                                                X         |             
                                            __________________________________________________________________________|             
   Mesentery                               |       +           +                                                      |             
      Leukemia Mononuclear                 |       X                                                                  |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Adenoma                              |          X                                      X                        |             
      Leukemia Mononuclear                 |       X  X                          X                                    |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                                        +  +              +           +   |             
      Sublingual Gland, Lymphoma Malignant |                                                                          |             
          Mixed                            |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |       X                             X                                    |             
                                            __________________________________________________________________________|             
   Tongue                                  |    +  M  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  78                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 6| 6| 7| 6| 7| 7| 5| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 9| 2| 2| 2| 6| 2| 2| 2| 6| 6| 0| 0| 9| 4| 0| 2| 7| 2| 0| 7| 2| 2| 9| 2| 6|             
                                           | 1| 9| 8| 4| 5| 9| 7| 4| 5| 3| 4| 4| 0| 3| 8| 9| 3| 9| 3| 4| 9| 9| 9| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM - cont              |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +                                +  +        +     +           +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Schwannoma Malignant                 |    X                                                                     |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +     +                    +  +  +        +     +           +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +     +                    +  +  +        +     +           +   |             
      Leukemia Mononuclear                 |       X  X                          X                                X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +     +                    +  +  +        +     +           +   |             
      Leukemia Mononuclear                 |       X  X                          X                                X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |    X     X     X                       X           X     X               |             
      Pheochromocytoma Benign, Multiple    |       X                                                                  |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |                                        +  +              +        +  +   |             
      Carcinoma                            |                                                                   X      |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    M  +  +     +  +  +        M  +  +  +  +  +  +  +  +  +  +  +  +  I   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Pars Distalis, Adenoma               |    X                          X        X        X  X        X            |             
      Pars Distalis, Adenoma, Multiple     |                                              X                           |             
      Pars Distalis, Leukemia Mononuclear  |       X                             X                          X     X   |             
      Pars Distalis, Pars Intermedia, Pars |                                                                          |             
          Nervosa, Leukemia Mononuclear    |                                                                          |             
      Pars Distalis, Pars Nervosa,         |                                                                          |             
          Leukemia Mononuclear             |                                                                          |             
      Pars Nervosa, Leukemia Mononuclear   |                                     X                                    |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |          +                       +  +  +  +              +           +   |             
      C-Cell, Adenoma                      |                                  X                                   X   |             
      C-Cell, Carcinoma                    |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Coagulating Gland                       |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |                                        +  +              +           +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |          +                       +     +  +              +           +   |             
      Adenoma                              |          X                                                               |             
      Carcinoma                            |                                                                          |             
                                            __________________________________________________________________________|             
   Prostate                                |                                        +  +              +           +   |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  79                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 6| 6| 7| 6| 7| 7| 5| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 9| 2| 2| 2| 6| 2| 2| 2| 6| 6| 0| 0| 9| 4| 0| 2| 7| 2| 0| 7| 2| 2| 9| 2| 6|             
                                           | 1| 9| 8| 4| 5| 9| 7| 4| 5| 3| 4| 4| 0| 3| 8| 9| 3| 9| 3| 4| 9| 9| 9| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                      +                 +  +              +        +  +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +     +  +  +        +  +  +  +  +  +     +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
      Interstitial Cell, Adenoma           |    X  X  X     X  X  X        X  X  X     X  X     X  X  X  X  X  X  X   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                                        +  +              +           +   |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +                       +        +  +  +           +  +        +   |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Mediastinal, Lymphoma Malignant Mixed|                                                                          |             
      Pancreatic, Leukemia Mononuclear     |       X                                                                  |             
      Renal, Leukemia Mononuclear          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  |       +                                +  +  +           +           +   |             
      Leukemia Mononuclear                 |       X                                                              X   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |       +                       +        +  +              +           +   |             
      Leukemia Mononuclear                 |       X                                                                  |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +     +     +           +  +  +  +  +  +  +  +  +     +  +  +   |             
      Hemangioma                           |                                                                          |             
      Hemangiosarcoma                      |    X                                                                     |             
      Leukemia Mononuclear                 |       X  X                       X  X        X        X        X     X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Sarcoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  |       +                                +  +              +           +   |             
      Leukemia Mononuclear                 |       X                                                                  |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |                                        +  +              +  +  +  +  +   |             
      Fibroadenoma                         |                                                             X  X  X      |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +     +                    +        +  +              +           +   |             
      Basosquamous Tumor Benign            |                                                                          |             
      Keratoacanthoma                      |                               X                                          |             
      Squamous Cell Papilloma              |          X                                                               |             
      Subcutaneous Tissue, Fibroma         |                                                                          |             
      Subcutaneous Tissue, Lymphoma        |                                                                          |             
          Malignant Mixed                  |                                                                          |             
      Subcutaneous Tissue, Myxoma          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  80                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 6| 6| 7| 6| 7| 7| 5| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 9| 2| 2| 2| 6| 2| 2| 2| 6| 6| 0| 0| 9| 4| 0| 2| 7| 2| 0| 7| 2| 2| 9| 2| 6|             
                                           | 1| 9| 8| 4| 5| 9| 7| 4| 5| 3| 4| 4| 0| 3| 8| 9| 3| 9| 3| 4| 9| 9| 9| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
      Subcutaneous Tissue, Sarcoma         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                                        +  +              +           +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |                                        +  +              +           +   |             
      Leukemia Mononuclear                 |                                                                      X   |             
      Choroid Plexus, Lymphoma Malignant   |                                                                          |             
          Mixed                            |                                                                          |             
                                            __________________________________________________________________________|             
   Peripheral Nerve                        |                                                 +                        |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                 +                        |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +                       +  +     +  +           +  +  +  +  +  +   |             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |             
          Multiple                         |                                                                          |             
      Carcinoma, Metastatic, Thyroid Gland |                                                                          |             
      Cholangiocarcinoma, Metastatic, Liver|                               X                                          |             
      Leukemia Mononuclear                 |       X                                               X        X     X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
      Mediastinum, Schwannoma Malignant,   |                                                                          |             
           Metastatic, Heart               |    X                                                                     |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |                                     X                 X        X     X   |             
                                            __________________________________________________________________________|             
   Trachea                                 |                                        +  +              +           +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                     +           +                        |             
                                            __________________________________________________________________________|             
   Eye                                     |       I        I                                                         |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |       X                             X                 X              X   |             
      Lymphoma Malignant Mixed             |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |                                     X                                    |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         |    +  +  +     +  +  +        +  +  +  +  +  +  +  +  +  +  +  +  +  +   |             
      Leukemia Mononuclear                 |       X  X                       X  X        X        X        X     X   |             
      Lymphoma Malignant Histiocytic       |                                                                          |             
      Lymphoma Malignant Mixed             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  81                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 1| 7| 7| 7| 4| 7| 7| 7| 4| 4| 7| 7| 6| 6| 6| 7| 6| 7| 7| 5| 7| 7| 6| 6| 4|             
                             DAY ON TEST   | 9| 2| 2| 2| 6| 2| 2| 2| 6| 6| 0| 0| 9| 4| 0| 2| 7| 2| 0| 7| 2| 2| 9| 2| 6|             
                                           | 1| 9| 8| 4| 5| 9| 7| 4| 5| 3| 4| 4| 0| 3| 8| 9| 3| 9| 3| 4| 9| 9| 9| 4| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    1.0% MM                                | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS - cont                   |                                                                          |             
                                           |                                                                          |             
      Mesothelioma Benign                  |                                                                          |             
      Mesothelioma Malignant               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  82                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 4| 4| 7| 7| 7| 7| 4| 7| 6| 1| 6| 6| 6| 5| 5| 4| 1|              |            |
                             DAY ON TEST   | 2| 2| 8| 6| 2| 2| 2| 2| 2| 2| 2| 9| 9| 1| 4| 7| 9| 4| 6| 9|              |            |
                                           | 9| 7| 4| 5| 7| 9| 9| 8| 7| 0| 4| 5| 1| 7| 3| 3| 2| 9| 5| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|              |     A      |
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               |             +              +           +  +     +  +                     |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         |       +     +              +           +  +     +  +                     |  13        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  |       +     +              +           +  +     +  +                     |  13        |
      Leukemia Mononuclear                 |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  |             +              +           +  +     +  +                     |  11        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 |             +              +           +  +     +  M                     |  10        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +     +  +  +  +  +  +  +  +     +  +  M  +  +                     |  48        |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  48        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | M  +  M     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  43        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
      Cholangiocarcinoma                   |                                                                          |          1 |
      Hemangiosarcoma                      |                                                                          |          1 |
      Hepatocellular Adenoma, Multiple     | X                                                                        |          1 |
      Leukemia Mononuclear                 | X  X                                   X  X  X     X                     |         22 |
      Lymphoma Malignant Histiocytic       |                         X                                                |          1 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Neoplastic Nodule                    |                X                                                         |          2 |
      Neoplastic Nodule, Multiple          |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |                            +                    +                        |   5        |
      Leukemia Mononuclear                 |                                                                          |          1 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Mesothelioma Malignant               |                            X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
      Adenoma                              |                                                                          |          2 |
      Leukemia Mononuclear                 | X                                      X                                 |          9 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |             +              +           +  +     +  +                     |  12        |
      Sublingual Gland, Lymphoma Malignant |                                                                          |            |
          Mixed                            |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +     +  +  +  +  +     +  +     +  +  +  +  +                     |  49        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +     +  +  +  +  +     +  +     +  +  +  +  +                     |  49        |
      Leukemia Mononuclear                 |                                              X                           |          3 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  83                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 4| 4| 7| 7| 7| 7| 4| 7| 6| 1| 6| 6| 6| 5| 5| 4| 1|              |            |
                             DAY ON TEST   | 2| 2| 8| 6| 2| 2| 2| 2| 2| 2| 2| 9| 9| 1| 4| 7| 9| 4| 6| 9|              |            |
                                           | 9| 7| 4| 5| 7| 9| 9| 8| 7| 0| 4| 5| 1| 7| 3| 3| 2| 9| 5| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|              |     A      |
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +  +  +     +  +  +  +  +  +  M  +     M  +  +  +  +                     |  47        |
      Leukemia Mononuclear                 |                                           X                              |          1 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +           +     +        +           +  +     +  +                     |  18        |
      Leukemia Mononuclear                 |                                        X  X                              |          4 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Schwannoma Malignant                 |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +        +              +     +     +  +     +  +                     |  21        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +        +              +     +     +  +     +  +                     |  21        |
      Leukemia Mononuclear                 |                                           X                              |          5 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +        +              +     +     +  +     +  +                     |  21        |
      Leukemia Mononuclear                 |                                           X                              |          5 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Pheochromocytoma Malignant           |    X                                                                     |          1 |
      Pheochromocytoma Benign              |                                  X        X                              |          9 |
      Pheochromocytoma Benign, Multiple    |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      |             +              +           +  +     +  +                     |  13        |
      Carcinoma                            |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  +  +     I  +  +  +  +  M  +  +     +  +  +  +  +                     |  43        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
      Pars Distalis, Adenoma               | X     X           X     X     X  X           X  X                        |         18 |
      Pars Distalis, Adenoma, Multiple     |                                                                          |          1 |
      Pars Distalis, Leukemia Mononuclear  |                                        X     X                           |         10 |
      Pars Distalis, Pars Intermedia, Pars |                                                                          |            |
          Nervosa, Leukemia Mononuclear    |                                           X                              |          1 |
      Pars Distalis, Pars Nervosa,         |                                                                          |            |
          Leukemia Mononuclear             |                                                    X                     |          1 |
      Pars Nervosa, Leukemia Mononuclear   |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           |       +     +  +  +        +           +  +  +  +  +                     |  22        |
      C-Cell, Adenoma                      |       X                                                                  |          4 |
      C-Cell, Carcinoma                    |       X                                                                  |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  84                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 4| 4| 7| 7| 7| 7| 4| 7| 6| 1| 6| 6| 6| 5| 5| 4| 1|              |            |
                             DAY ON TEST   | 2| 2| 8| 6| 2| 2| 2| 2| 2| 2| 2| 9| 9| 1| 4| 7| 9| 4| 6| 9|              |            |
                                           | 9| 7| 4| 5| 7| 9| 9| 8| 7| 0| 4| 5| 1| 7| 3| 3| 2| 9| 5| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|              |     A      |
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Coagulating Gland                       |             +                                +                           |   2        |
                                            __________________________________________________________________________|____________|
   Epididymis                              |             +              +           +  +     +  +                     |  13        |
      Mesothelioma Malignant               |                            X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +     +     +              +  +        +  +     +  +                     |  19        |
      Adenoma                              | X                             X                                          |          3 |
      Carcinoma                            |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Prostate                                |             +              +           +  +     +  +                     |  12        |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         | +     +     +     +  +     +           +  +     +  +                     |  23        |
      Mesothelioma Malignant               |                            X                                             |          1 |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +     +  +     +  +  +  +  +     +  +  +  +  +                     |  48        |
      Leukemia Mononuclear                 |                                                                          |          1 |
      Mesothelioma Benign                  |                                                 X                        |          1 |
      Mesothelioma Malignant               |                            X                                             |          2 |
      Interstitial Cell, Adenoma           | X  X  X        X     X  X  X  X  X     X  X  X  X  X                     |         45 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |             +              +           +  +     +  +                     |  12        |
      Leukemia Mononuclear                 |                                        X                                 |          1 |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +     +     +              +  +        +  +     +  +                     |  26        |
      Carcinoma, Metastatic, Thyroid Gland |       X                                                                  |          1 |
      Mediastinal, Leukemia Mononuclear    | X                                      X  X                              |          4 |
      Mediastinal, Lymphoma Malignant Mixed|                                                 X                        |          1 |
      Pancreatic, Leukemia Mononuclear     | X                                      X                                 |          5 |
      Renal, Leukemia Mononuclear          | X                                         X                              |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  |             +              +  +        +  +     +  +                     |  15        |
      Leukemia Mononuclear                 |                                        X  X        X                     |          6 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |             +              +           +  +     +  +                     |  17        |
      Leukemia Mononuclear                 |                                        X  X        X                     |          5 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +           +     +        +           +  +  +  +  +                     |  38        |
      Hemangioma                           |                                                                          |          1 |
      Hemangiosarcoma                      |                                                                          |          1 |
      Leukemia Mononuclear                 | X                                      X  X  X     X                     |         18 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Sarcoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |             +              +           +  +     +  +                     |  13        |
      Leukemia Mononuclear                 |                                        X  X                              |          3 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  85                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 4| 4| 7| 7| 7| 7| 4| 7| 6| 1| 6| 6| 6| 5| 5| 4| 1|              |            |
                             DAY ON TEST   | 2| 2| 8| 6| 2| 2| 2| 2| 2| 2| 2| 9| 9| 1| 4| 7| 9| 4| 6| 9|              |            |
                                           | 9| 7| 4| 5| 7| 9| 9| 8| 7| 0| 4| 5| 1| 7| 3| 3| 2| 9| 5| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|              |     A      |
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +           +              M           +  +  +  M  M                     |  14        |
      Fibroadenoma                         | X                                            X                           |          5 |
      Leukemia Mononuclear                 |                                              X                           |          1 |
                                            __________________________________________________________________________|____________|
   Skin                                    | +           M     +     +  +           +  +     +  M                     |  19        |
      Basosquamous Tumor Benign            | X                                                                        |          1 |
      Keratoacanthoma                      |                                                                          |          1 |
      Squamous Cell Papilloma              |                   X                                                      |          3 |
      Subcutaneous Tissue, Fibroma         |                                                                          |          1 |
      Subcutaneous Tissue, Lymphoma        |                                                                          |            |
          Malignant Mixed                  |                                                 X                        |          1 |
      Subcutaneous Tissue, Myxoma          |                         X                                                |          1 |
      Subcutaneous Tissue, Sarcoma         |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    |    M        +        M     +     +     +  +  +  +  +                     |  15        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   |             +              +           +  +     +  +                     |  12        |
      Leukemia Mononuclear                 |                                        X  X                              |          4 |
      Choroid Plexus, Lymphoma Malignant   |                                                                          |            |
          Mixed                            |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Peripheral Nerve                        |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                  +                                       |   2        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +     +              +  +  +     +  +  +  +  +                     |  31        |
      Alveolar/Bronchiolar Adenoma         |             X                                                            |          1 |
      Alveolar/Bronchiolar Carcinoma,      |                                                                          |            |
          Multiple                         |             X                                                            |          1 |
      Carcinoma, Metastatic, Thyroid Gland |       X                                                                  |          1 |
      Cholangiocarcinoma, Metastatic, Liver|                                                                          |          1 |
      Leukemia Mononuclear                 | X                                      X  X  X     X                     |         12 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Mediastinum, Schwannoma Malignant,   |                                                                          |            |
           Metastatic, Heart               |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  49        |
      Leukemia Mononuclear                 |                                                                          |          5 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  86                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 7| 6| 4| 4| 7| 7| 7| 7| 4| 7| 6| 1| 6| 6| 6| 5| 5| 4| 1|              |            |
                             DAY ON TEST   | 2| 2| 8| 6| 2| 2| 2| 2| 2| 2| 2| 9| 9| 1| 4| 7| 9| 4| 6| 9|              |            |
                                           | 9| 7| 4| 5| 7| 9| 9| 8| 7| 0| 4| 5| 1| 7| 3| 3| 2| 9| 5| 1|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|              |     A      |
    1.0% MM                                | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Trachea                                 |             +              +           +  +     +  +                     |  12        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   2        |
                                            __________________________________________________________________________|____________|
   Eye                                     | +     +                          I           I     +                     |   6        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                    +                     |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 |                                        X  X  X                           |          9 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +     +  +  +  +  +  +  +  +     +  +  M  +  +                     |  49        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +     +  +  +  +  +  +  +  +     +  +  +  +  +                     |  50        |
      Leukemia Mononuclear                 | X  X                                   X  X  X     X                     |         22 |
      Lymphoma Malignant Histiocytic       |                         X                                                |          1 |
      Lymphoma Malignant Mixed             |                                                 X                        |          1 |
      Mesothelioma Benign                  |                                                 X                        |          1 |
      Mesothelioma Malignant               |                            X                                             |          2 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  87                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 3| 7| 6| 1| 7| 7| 6| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 4| 7| 6| 4| 3| 1|             
                             DAY ON TEST   | 2| 1| 0| 9| 8| 2| 2| 7| 8| 8| 2| 2| 2| 8| 6| 2| 2| 2| 2| 6| 0| 2| 6| 2| 8|             
                                           | 7| 5| 0| 0| 9| 7| 9| 3| 9| 9| 9| 7| 7| 6| 5| 8| 8| 8| 9| 3| 4| 6| 3| 6| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  M  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  M  +  A     +  +  +        +  +  +  M     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  A  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  A  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  A  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  A  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     A   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  A  +  A     +  +  +        +  +  +  A     +  +  +  +     +  +     A   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Hepatocellular Carcinoma             |                                  X                                       |             
      Leukemia Mononuclear                 |                X  X                          X     X  X     X            |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                 +                        |             
      Sarcoma, Poorly Differentiated       |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  M  +  +     +  +  +        +  +  +  A     +  +  +  +     +  +     A   |             
      Leukemia Mononuclear                 |                                                    X  X     X            |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +                                         +  M           +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +     +  +     +  +           +     +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Tongue                                  | M  M  +  +     +  +  +        +  +  M  +     +  +  +  +     +  +     M   |             
      Squamous Cell Papilloma              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                                                    X                     |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                                                    X                     |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |                   X  X        X                                          |             
      Pheochromocytoma Benign, Multiple    |                                                 X                        |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  M                 +        +  +  +  +     +  +  M  +     +  +     A   |             
      Adenoma                              |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  M  +  +     +  +  +        +  I  +  +     +  +  +  +     +  +     M   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  A  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Pars Distalis, Adenoma               |       X  X           X           X              X                        |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  88                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 3| 7| 6| 1| 7| 7| 6| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 4| 7| 6| 4| 3| 1|             
                             DAY ON TEST   | 2| 1| 0| 9| 8| 2| 2| 7| 8| 8| 2| 2| 2| 8| 6| 2| 2| 2| 2| 6| 0| 2| 6| 2| 8|             
                                           | 7| 5| 0| 0| 9| 7| 9| 3| 9| 9| 9| 7| 7| 6| 5| 8| 8| 8| 9| 3| 4| 6| 3| 6| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +     +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      C-Cell, Adenoma                      |                                                                          |             
      Follicular Cell, Adenocarcinoma      |                                                                          |             
      Follicular Cell, Adenoma             |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +     +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Mesothelioma Malignant               |                                                             X            |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +     +           +                 +                       +     +   |             
      Adenoma                              |                                                                          |             
      Carcinoma                            |                                                                X         |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +     +  +  M        +  +  +  M     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +     +  +  +        +  +  +  M     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Mesothelioma Malignant               |                                                             X            |             
      Interstitial Cell, Adenoma           | X     X  X     X  X  X        X  X  X  X     X  X  X  X     X  X         |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +                                                           +     +   |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Mediastinal, Leukemia Mononuclear    |                                                             X            |             
      Pancreatic, Leukemia Mononuclear     |                                                    X                     |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  M     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    M  +           +                    +                    +  +     +   |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                X                             X     X  X     X            |             
                                            __________________________________________________________________________|             
   Thymus                                  |    M                                                                 M   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    M                          +                 +              +     M   |             
      Fibroadenoma                         |                               X                 X                        |             
                                            __________________________________________________________________________|             
   Skin                                    |    +           +  +  +                       +                 +     +   |             
      Squamous Cell Papilloma              |                                                                          |             
      Subcutaneous Tissue, Fibroma         |                      X                                                   |             
      Subcutaneous Tissue, Sarcoma         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +           +                    +        +     +     +  +     +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  89                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 3| 7| 6| 1| 7| 7| 6| 1| 1| 7| 7| 7| 6| 4| 7| 7| 7| 7| 4| 7| 6| 4| 3| 1|             
                             DAY ON TEST   | 2| 1| 0| 9| 8| 2| 2| 7| 8| 8| 2| 2| 2| 8| 6| 2| 2| 2| 2| 6| 0| 2| 6| 2| 8|             
                                           | 7| 5| 0| 0| 9| 7| 9| 3| 9| 9| 9| 7| 7| 6| 5| 8| 8| 8| 9| 3| 4| 6| 3| 6| 9|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 4|             
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Leukemia Mononuclear                 |                                                                          |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Alveolar/Bronchiolar Adenoma         |                X                                                         |             
      Leukemia Mononuclear                 |                                                    X  X     X            |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic, Adrenal Gland        |                                                                          |             
      Squamous Cell Carcinoma              |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Squamous Cell Papilloma              |                               X                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                             +            |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                                                    X                     |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Adenoma                         |                                                                          |             
      Renal Tubule, Adenocarcinoma         |                                                                          |             
      Renal Tubule, Adenoma                |                                                       X                  |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +     +  +  +        +  +  +  A     +  +  +  +     +  +     M   |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +     +  +  +        +  +  +  +     +  +  +  +     +  +     +   |             
      Leukemia Mononuclear                 |                X  X                          X     X  X     X            |             
      Mesothelioma Malignant               |                                                             X            |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  90                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 6| 6| 6| 1| 4| 1| 6| 5| 4| 4| 1| 7| 7| 6| 4| 4| 6| 6| 1| 5| 4|             
                             DAY ON TEST   | 2| 2| 2| 9| 7| 6| 1| 8| 6| 9| 9| 8| 6| 6| 9| 2| 2| 9| 6| 6| 7| 7| 9| 5| 6|             
                                           | 8| 9| 4| 7| 6| 7| 7| 9| 5| 1| 4| 1| 5| 3| 1| 3| 7| 3| 3| 3| 6| 4| 1| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    4.0% HM                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
      Adenoma                              |                                                 X                        |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Hepatocellular Carcinoma             |                                                                          |             
      Leukemia Mononuclear                 | X        X                    X                    X                     |             
                                            __________________________________________________________________________|             
   Mesentery                               |                +                             +                           |             
      Sarcoma, Poorly Differentiated       |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 | X        X                                                               |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |                   +              +                                   +   |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  A  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Tongue                                  | +  +  +  +  +  +  +           +  +           +  M  +        +  +     +   |             
      Squamous Cell Papilloma              |                                                                X         |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |             +                                                            |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  M  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +  M  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 |          X                                                               |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +  M  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Pheochromocytoma Malignant           |                                                                          |             
      Pheochromocytoma Benign              |       X     X                                                            |             
      Pheochromocytoma Benign, Multiple    |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Adenoma                              | X                             X                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  +  +  +           +  +           +  +  +        +  +     M   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  M  +  +           +  +           +  +  +        +  +     +   |             
      Pars Distalis, Adenoma               | X                                X           X              X            |             
      Pars Distalis, Adenoma, Multiple     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  91                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 6| 6| 6| 1| 4| 1| 6| 5| 4| 4| 1| 7| 7| 6| 4| 4| 6| 6| 1| 5| 4|             
                             DAY ON TEST   | 2| 2| 2| 9| 7| 6| 1| 8| 6| 9| 9| 8| 6| 6| 9| 2| 2| 9| 6| 6| 7| 7| 9| 5| 6|             
                                           | 8| 9| 4| 7| 6| 7| 7| 9| 5| 1| 4| 1| 5| 3| 1| 3| 7| 3| 3| 3| 6| 4| 1| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    4.0% HM                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      C-Cell, Adenoma                      |             X                                                            |             
      Follicular Cell, Adenocarcinoma      |                                                             X            |             
      Follicular Cell, Adenoma             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Mesothelioma Malignant               |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |       +           +              +                 +                 +   |             
      Adenoma                              |                                                                          |             
      Carcinoma                            |       X                                            X                     |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Mesothelioma Malignant               |                                                                          |             
      Interstitial Cell, Adenoma           | X  X  X  X  X  X  X           X              X  X  X           X     X   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |                +  +              +                                   +   |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Mediastinal, Leukemia Mononuclear    |                                                                          |             
      Pancreatic, Leukemia Mononuclear     |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mandibular                  | +  +  +  +  +  +  +           +  +           +  +  +        +  +     M   |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |             +  +  +           +  +           +              +        +   |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 | X        X                    X                    X                     |             
                                            __________________________________________________________________________|             
   Thymus                                  |                +  +              +                                   +   |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |                   +              +           +                       +   |             
      Fibroadenoma                         |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |       +           +              +           +              +  +     +   |             
      Squamous Cell Papilloma              |                                                             X            |             
      Subcutaneous Tissue, Fibroma         |       X                                                                  |             
      Subcutaneous Tissue, Sarcoma         |                                                                      X   |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |                +  +           +  +                          +        +   |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  92                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 7| 7| 7| 6| 6| 6| 6| 1| 4| 1| 6| 5| 4| 4| 1| 7| 7| 6| 4| 4| 6| 6| 1| 5| 4|             
                             DAY ON TEST   | 2| 2| 2| 9| 7| 6| 1| 8| 6| 9| 9| 8| 6| 6| 9| 2| 2| 9| 6| 6| 7| 7| 9| 5| 6|             
                                           | 8| 9| 4| 7| 6| 7| 7| 9| 5| 1| 4| 1| 5| 3| 1| 3| 7| 3| 3| 3| 6| 4| 1| 5| 3|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    4.0% HM                                | 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|             
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Leukemia Mononuclear                 |          X                                                               |             
                                            __________________________________________________________________________|             
   Spinal Cord                             |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Alveolar/Bronchiolar Adenoma         |                                                                          |             
      Leukemia Mononuclear                 | X        X                                                               |             
      Pheochromocytoma Malignant,          |                                                                          |             
          Metastatic, Adrenal Gland        |                                                                          |             
      Squamous Cell Carcinoma              |                X                                                         |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Squamous Cell Papilloma              |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                   +                                                      |             
                                            __________________________________________________________________________|             
   Eye                                     |             +     +                                                      |             
                                            __________________________________________________________________________|             
   Harderian Gland                         |                   +                                                      |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 |          X                                                               |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Adenoma                         |                                                                          |             
      Renal Tubule, Adenocarcinoma         |       X                                                                  |             
      Renal Tubule, Adenoma                |             X                                                            |             
                                            __________________________________________________________________________|             
   Urethra                                 |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
 _____________________________________________________________________________________________________________________|             
 SYSTEMIC LESIONS                          |                                                                          |             
                                            __________________________________________________________________________|             
   Multiple Organs                         | +  +  +  +  +  +  +           +  +           +  +  +        +  +     +   |             
      Leukemia Mononuclear                 | X        X                    X                    X                     |             
      Mesothelioma Malignant               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  93                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 6| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 1| 1| 6| 4|              |            |
                             DAY ON TEST   | 2| 2| 2| 6| 7| 2| 2| 1| 1| 9| 2| 2| 2| 2| 2| 2| 9| 9| 9| 6|              |            |
                                           | 8| 2| 4| 2| 4| 4| 3| 5| 3| 8| 8| 8| 9| 9| 4| 8| 1| 1| 2| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|              |     A      |
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  I  +  +  +  +  +        I                  |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  45        |
      Adenoma                              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  M  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  44        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Hepatocellular Carcinoma             |                                                                          |          1 |
      Leukemia Mononuclear                 |          X                 X        X                                    |         13 |
                                            __________________________________________________________________________|____________|
   Mesentery                               |    +  +                                                                  |   5        |
      Sarcoma, Poorly Differentiated       |    X                                                                     |          1 |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  47        |
      Leukemia Mononuclear                 |                                                                          |          5 |
                                            __________________________________________________________________________|____________|
   Salivary Glands                         |    +        +                                                            |  10        |
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  46        |
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  I  +  +  +  +  +  +        +                  |  48        |
                                            __________________________________________________________________________|____________|
   Tongue                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  M  +  +        +                  |  44        |
      Squamous Cell Papilloma              |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |                                                       +                  |   2        |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
      Leukemia Mononuclear                 |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
      Leukemia Mononuclear                 |                                                                          |          2 |
      Pheochromocytoma Malignant           |          X        X                                                      |          2 |
      Pheochromocytoma Benign              |       X  X                    X                       X                  |          9 |
      Pheochromocytoma Benign, Multiple    |                         X                                                |          2 |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +     +     +  +  +        +                  |  41        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  94                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 6| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 1| 1| 6| 4|              |            |
                             DAY ON TEST   | 2| 2| 2| 6| 7| 2| 2| 1| 1| 9| 2| 2| 2| 2| 2| 2| 9| 9| 9| 6|              |            |
                                           | 8| 2| 4| 2| 4| 4| 3| 5| 3| 8| 8| 8| 9| 9| 4| 8| 1| 1| 2| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|              |     A      |
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Adenoma                              |                         X                                                |          3 |
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  I  +  I  +  +  +  +  +  M  +  +  +  +  +  +        +                  |  43        |
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  48        |
      Pars Distalis, Adenoma               |    X              X                                                      |         11 |
      Pars Distalis, Adenoma, Multiple     |                      X                                                   |          1 |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
      C-Cell, Adenoma                      |                                                                          |          1 |
      Follicular Cell, Adenocarcinoma      |                                                                          |          1 |
      Follicular Cell, Adenoma             |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
      Mesothelioma Malignant               |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Preputial Gland                         |    +                          +        +     +                           |  15        |
      Adenoma                              |                                              X                           |          1 |
      Carcinoma                            |                                                                          |          3 |
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  48        |
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Mesothelioma Malignant               |                                                                          |          1 |
      Interstitial Cell, Adenoma           | X     X  X  X  X  X  X  X  X  X  X  X  X  X  X        X                  |         45 |
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             |    +        +                                                            |   9        |
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Mediastinal, Leukemia Mononuclear    |                                                                          |          1 |
      Pancreatic, Leukemia Mononuclear     |                            X                                             |          2 |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mandibular                  | +  M  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  47        |
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  |    +        +              +     +                    +                  |  19        |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Leukemia Mononuclear                 |                            X        X                                    |         11 |
                                            __________________________________________________________________________|____________|
   Thymus                                  |    M        +                                                            |   5        |
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           |    +                             +                                       |   9        |
      Fibroadenoma                         |                                  X                                       |          3 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  95                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 6| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 1| 1| 6| 4|              |            |
                             DAY ON TEST   | 2| 2| 2| 6| 7| 2| 2| 1| 1| 9| 2| 2| 2| 2| 2| 2| 9| 9| 9| 6|              |            |
                                           | 8| 2| 4| 2| 4| 4| 3| 5| 3| 8| 8| 8| 9| 9| 4| 8| 1| 1| 2| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|              |     A      |
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 INTEGUMENTARY SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Skin                                    |    +        +                    +  +                                    |  18        |
      Squamous Cell Papilloma              |                                                                          |          1 |
      Subcutaneous Tissue, Fibroma         |             X                                                            |          3 |
      Subcutaneous Tissue, Sarcoma         |                                                                          |          1 |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +     +  +        +  +           +                 +                  |  23        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Leukemia Mononuclear                 |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Spinal Cord                             |                                                       +                  |   1        |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Alveolar/Bronchiolar Adenoma         |                                                                          |          1 |
      Leukemia Mononuclear                 |                            X        X                                    |          7 |
      Pheochromocytoma Malignant,          |                                                                          |            |
          Metastatic, Adrenal Gland        |          X                                                               |          1 |
      Squamous Cell Carcinoma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +     +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  49        |
      Squamous Cell Papilloma              |                                                                          |          1 |
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   3        |
                                            __________________________________________________________________________|____________|
   Harderian Gland                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
      Leukemia Mononuclear                 |                            X                                             |          3 |
      Proximal Convoluted Renal Tubule,    |                                                                          |            |
           Adenoma                         |                                     X                                    |          1 |
      Renal Tubule, Adenocarcinoma         |                                                                          |          1 |
      Renal Tubule, Adenoma                |                                                                          |          2 |
                                            __________________________________________________________________________|____________|
   Urethra                                 |    +                                                                     |   1        |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  48        |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS                          |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Multiple Organs                         | +  +  +  +  +  +  +  +  +  +  +  +  +  +  +  +        +                  |  50        |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  96                                                               
NTP Experiment-Test: 05033-01                        NEOPLASMS BY INDIVIDUAL ANIMAL                               Report: PEIRPT04
Study Type: CHRONIC                                             QUERCETIN                                         Date: 04/09/97  
Route: DOSED FEED                                                                                                 Time: 10:08:26  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 7| 4| 7| 6| 5| 7| 7| 7| 7| 6| 7| 7| 7| 7| 7| 7| 1| 1| 6| 4|              |            |
                             DAY ON TEST   | 2| 2| 2| 6| 7| 2| 2| 1| 1| 9| 2| 2| 2| 2| 2| 2| 9| 9| 9| 6|              |            |
                                           | 8| 2| 4| 2| 4| 4| 3| 5| 3| 8| 8| 8| 9| 9| 4| 8| 1| 1| 2| 3|              |            |
 _____________________________________________________________________________________________________________________|     T (*)  |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     O      |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|              |     T      |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|              |     A      |
    4.0% HM                                | 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|              |     L      |
                                           | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|              |            |
 __________________________________________________________________________________________________________________________________ 
 SYSTEMIC LESIONS - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Leukemia Mononuclear                 |          X                 X        X                                    |         13 |
      Mesothelioma Malignant               |                                                                          |          1 |
 __________________________________________________________________________________________________________________________________ 
                         * : Total animals with tissue examined microscopically; total animals with tumor                           
                         + : Tissue examined microscopically                      M : Missing tissue                                
                         X : Lesion present                                       A : Autolysis precludes evaluation                
                         I : Insufficient tissue                              BLANK : Not examined microscopically                  
                                                             Page  97                                                               
                                  ------------------------------------------------------------                                      
                                  ----------              END OF REPORT             ----------                                      
                                  ------------------------------------------------------------                                      
NTP is located at the National Institute of Environmental Health Sciences, part of the National Institutes of Health.