TDMS Study 05110-02 Pathology Tables
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: Battelle Northwest NAPHTHALENE DATE: 03/06/00
EXPERIMENT: 05110 TEST: 02 TIME: 11:18:13
CAGES FROM 0000 TO LAST CAGE PAGE: 1
TEST TYPE: CHRONIC ROUTE: RESPIRATORY EXPOSURE WHOLE BODY NTP: C52904C
CONT: NO1-ES-55392 CAS: 91-20-3
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REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41
LAB: BATTELLE NORTHWEST NAPHTHALENE DATE: 03/06/00
EXPERIMENT: 05110 TEST: 02 TIME: 11:23:33
SPECIES: RATS, FISCHER 344
TEST TYPE: TWO YEAR ROUTE: RESPIRATORY EX NTP: 52904C
CONT: NO1-ES-55392 CAS: 91-20-3
MEAN BODY WEIGHTS AND SURVIVAL OF MALE RATS IN THE
TWO YEAR RESPIRATORY EX STUDY OF NAPHTHALENE
==========================================================================================================
WEEK CONTROL 10 PPM 30 PPM 60 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 124.6 49 121.9 97.8 49 122.6 98.4 48* 121.6 97.6 49
1 124.6 49 121.9 97.8 49 122.6 98.4 48* 121.6 97.6 49
4 231.1 49 211.1 91.3 49 210.8 91.2 48* 205.6 89.0 49
8 293.4 49 266.5 90.8 49 266.9 91.0 48 257.1 87.6 49
12 342.5 49 313.7 91.6 49 312.4 91.2 48 302.0 88.2 49
16 370.9 49 342.5 92.3 49 338.9 91.4 48 327.6 88.3 49
20 396.3 49 366.7 92.5 49 360.8 91.0 48 349.6 88.2 49
24 416.3 49 384.6 92.4 49 378.1 90.8 48 367.9 88.4 49
28 430.5 49 401.3 93.2 49 395.7 91.9 48 381.1 88.5 49
32 442.6 49 413.6 93.4 49 405.8 91.7 48 392.5 88.7 49
36 455.1 49 426.1 93.6 49 419.7 92.2 48 406.6 89.3 48
40 463.5 49 434.9 93.8 49 426.6 92.0 48 412.4 89.0 48
44 468.7 49 439.4 93.7 49 433.0 92.4 48 417.6 89.1 48
48 479.5 49 450.5 94.0 49 443.3 92.5 48 426.5 88.9 48
52 478.9 49 455.2 95.1 49 448.0 93.5 48 431.6 90.1 48
56 487.6 49 460.5 94.4 48 453.1 92.9 48 437.5 89.7 48
60 491.5 49 463.4 94.3 48 458.4 93.3 48 438.4 89.2 47
64 496.4 49 471.4 95.0 47 465.1 93.7 47 444.4 89.5 46
68 504.6 46 477.2 94.6 47 471.5 93.4 47 450.2 89.2 45
72 505.5 45 477.0 94.4 46 475.2 94.0 46 456.7 90.3 44
76 504.5 44 475.2 94.2 43 473.6 93.9 45 450.1 89.2 42
80 507.1 44 477.7 94.2 42 475.2 93.7 44 453.1 89.4 40
84 505.4 43 477.5 94.5 41 485.0 96.0 40 461.5 91.3 36
88 499.1 43 478.5 95.9 39 477.3 95.6 37 463.3 92.8 34
92 501.0 38 474.6 94.7 38 467.3 93.3 35 462.4 92.3 31
94 496.4 38 480.0 96.7 34 468.1 94.3 32 457.2 92.1 31
96 499.1 34 480.2 96.2 33 470.9 94.3 31 458.9 91.9 28
98 498.0 32 487.6 97.9 26 470.3 94.4 28 457.2 91.8 27
100 494.0 30 485.4 98.3 25 480.2 97.2 26 463.4 93.8 25
102 487.7 27 482.7 99.0 24 483.1 99.1 24 466.7 95.7 22
104 494.6 24 469.3 94.9 22 468.1 94.6 24 465.6 94.1 21
TERM. SAC. 24 22 23 21
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.
MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE
TWO YEAR RESPIRATORY EX STUDY OF NAPHTHALENE
==========================================================================================================
WEEK CONTROL 10 PPM 30 PPM 60 PPM
---------------- ---------------- ---------------- ----------------
AV.WT. NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO. AV.WT. PERCENT NO.
(GRAMS) (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A) (GRAMS) OF CNTL (A)
=========================================================================================================
B 100.0 49 100.5 100.5 49 100.0 100.0 49 99.7 99.7 49
1 100.0 49 100.5 100.5 49 100.0 100.0 49 99.7 99.7 49
4 148.3 49 140.9 95.0 49 138.5 93.4 49 138.1 93.1 49
8 168.6 49 161.7 95.9 49 160.3 95.1 49 158.8 94.2 49
12 186.9 49 179.8 96.2 49 180.2 96.4 49 177.4 94.9 49
16 195.1 49 191.1 97.9 49 190.4 97.6 49 185.1 94.9 49
20 204.4 49 203.1 99.4 49 201.5 98.6 49 196.3 96.0 48
24 211.4 49 211.3 100.0 49 210.1 99.4 49 201.8 95.5 48
28 215.7 49 219.2 101.6 49 218.3 101.2 49 209.7 97.2 48
32 217.1 49 226.2 104.2 49 224.4 103.4 49 215.3 99.2 48
36 230.9 49 237.3 102.8 49 236.5 102.4 49 227.3 98.4 48
40 235.8 49 241.6 102.5 49 240.7 102.1 49 229.8 97.5 48
44 239.8 49 249.8 104.2 49 246.2 102.7 49 236.6 98.7 48
48 253.9 49 262.4 103.3 49 257.0 101.2 49 249.0 98.1 48
52 262.4 49 269.6 102.7 49 264.3 100.7 49 254.0 96.8 48
56 271.8 49 280.4 103.2 49 273.4 100.6 49 262.7 96.7 48
60 278.9 49 286.8 102.8 49 280.9 100.7 49 269.0 96.5 48
64 287.3 49 293.9 102.3 48 287.8 100.2 47 275.5 95.9 46
68 295.0 49 301.3 102.1 47 295.9 100.3 47 281.6 95.5 46
72 303.0 49 307.3 101.4 47 301.7 99.6 46 289.4 95.5 44
76 306.1 47 307.2 100.4 44 300.9 98.3 45 290.9 95.0 43
80 313.0 47 310.0 99.0 44 306.1 97.8 45 295.7 94.5 40
84 319.7 46 314.3 98.3 40 308.8 96.6 43 301.7 94.4 39
88 321.7 44 313.8 97.5 37 313.8 97.5 40 301.7 93.8 38
92 325.2 43 322.2 99.1 34 315.3 97.0 37 300.2 92.3 33
94 318.8 43 318.0 99.7 33 316.9 99.4 35 307.6 96.5 31
96 318.9 41 318.1 99.7 31 320.2 100.4 34 307.1 96.3 30
98 324.7 34 328.6 101.2 26 324.3 99.9 33 309.1 95.2 27
100 324.7 33 326.5 100.6 26 324.2 99.8 32 309.4 95.3 26
102 321.1 31 326.4 101.7 25 323.8 100.8 30 305.7 95.2 26
104 320.2 29 329.5 102.9 21 328.7 102.7 28 306.9 95.8 24
TERM. SAC. 28 21 28 24
==========================================================================================================
(A) NUMBER OF ANIMALS WEIGHED. AT TERMINAL SACRIFICE, NUMBER
OF ANIMALS ALIVE ON FIRST DAY OF TERMINAL SACRIFICE.
(B) REFERS TO THE BEGINNING (INITIAL) BODY WEIGHT.
(I) INTERIM SACRIFICE OCCURRED IN THIS WEEK.
(*) THE NUMBER OF ANIMALS WEIGHED FOR THIS WEEK
IS LESS THAN THE NUMBER OF ANIMALS SURVIVING.