TDMS Study 05165-02 Pathology Tables
NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Columbus 4,4 THIOBIS-(6-T-BUTYL-M-CRESOL) DATE: 11/09/95
EXPERIMENT: 05165 TEST: 02 TIME: 20:41:50
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE PAGE: 1
CONT: N01-ES-65156 ROUTE: DOSED FEED NTP C#: 61610B
PATHOLOGIST: R. PERSING CAS: 96-69-5
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Columbus 4,4 THIOBIS-(6-T-BUTYL-M-CRESOL) DATE: 11/09/95
EXPERIMENT: 05165 TEST: 02 TIME: 20:41:50
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE
CONT: N01-ES-65156 ROUTE: DOSED FEED NTP C#: 61610B
PATHOLOGIST: R. PERSING CAS: 96-69-5
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 0 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 8 CENSORED DEATHS 10 TERMINAL 42 |
| |
| UNCENSORED DEATHS |
| 508 620 652 655 683 683 690 712 |
| CENSORED DEATHS |
| 456 456 456 456 456 456 456 456 456 456 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 250 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 8 CENSORED DEATHS 10 TERMINAL 42 |
| |
| UNCENSORED DEATHS |
| 489 507 557 573 638 661 680 709 |
| CENSORED DEATHS |
| 456 456 456 456 456 456 456 456 456 456 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 500 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 1 CENSORED DEATHS 10 TERMINAL 49 |
| |
| UNCENSORED DEATHS |
| 682 |
| CENSORED DEATHS |
| 456 456 456 456 456 456 456 456 456 456 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 1000 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 5 CENSORED DEATHS 10 TERMINAL 45 |
| |
| UNCENSORED DEATHS |
| 595 638 670 701 724 |
| CENSORED DEATHS |
| 456 456 456 456 456 456 456 456 456 456 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
==================================================================================
| KAPLAN-MEIER SURVIVAL PROBABILITY ESTIMATES (%) |
| |
|--------------------------------------------------------------------------------|
| DOSE TIME (DAYS) |
| 90 180 270 365 425 485 545 605 665 729 (A) |
| |
|--------------------------------------------------------------------------------|
| | |
|0 PPM | 100.0 100.0 100.0 100.0 100.0 100.0 98.0 98.0 92.0 84.0 |
| | |
| | |
|250 PPM | 100.0 100.0 100.0 100.0 100.0 100.0 96.0 92.0 88.0 84.0 |
| | |
| | |
|500 PPM | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 98.0 |
| | |
| | |
|1000 PPM | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 98.0 96.0 90.0 |
| | |
| | |
==================================================================================
==================================================================================
| SURVIVAL SUMMARY STATISTICS |
| |
| |
|--------------------------------------------------------------------------------|
| DOSE |
| |
| 0 PPM 250 PPM 500 PPM 1000 PPM |
| |
|--------------------------------------------------------------------------------|
|SURVIVAL AT END OF STUDY| 84.0% 84.0% 98.0% 90.0% |
|(KAPLAN-MEIER) | |
| | |
|SIGNIFICANCE (B) | P=0.242N P=1.000 P=0.036N P=0.536N |
|(LIFE TABLE) | |
| | |
|MEAN DAY OF | 650.4 601.8 682.0 665.6 |
|NATURAL DEATHS (C) | (22.6) (29.0) ( . ) (22.8) |
|(STANDARD ERROR) | |
| | |
|MEAN LIFE SPAN (D) | 673.0 666.5 682.7 678.2 |
|(STANDARD ERROR) | (13.4) (13.9) (13.2) (13.2) |
| | |
==================================================================================
(A) FIRST TERMINAL SACRIFICE
(B) THE FIRST ENTRY IS THE TREND TEST (TARONE, 1975) RESULT.
SUBSEQUENT ENTRIES ARE THE RESULTS OF PAIRWISE TESTS
(COX,1972). NEGATIVE TRENDS ARE INDICATED BY "N".
(C) MEAN OF ALL UNCENSORED DEATHS PRIOR TO TERMINAL SACRIFICE
(D) MEAN OF ALL DEATHS (UNCENSORED, CENSORED, TERMINAL SACRIFICE)
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 0 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 11 CENSORED DEATHS 9 TERMINAL 40 |
| |
| UNCENSORED DEATHS |
| 369 369 386 522 564 593 612 622 705 712 |
| 724 |
| CENSORED DEATHS |
| 457 457 457 457 457 457 457 457 457 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 250 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 12 CENSORED DEATHS 10 TERMINAL 38 |
| |
| UNCENSORED DEATHS |
| 450 521 599 603 605 665 666 674 697 705 |
| 718 723 |
| CENSORED DEATHS |
| 165 457 457 457 457 457 457 457 457 457 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 500 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 14 CENSORED DEATHS 10 TERMINAL 36 |
| |
| UNCENSORED DEATHS |
| 68 497 568 599 626 632 655 655 661 677 |
| 685 701 704 717 |
| CENSORED DEATHS |
| 457 457 457 457 457 457 457 457 457 457 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 1000 PPM |
| --------------------- |
| |
| TOTAL 60 UNCENSORED DEATHS 15 CENSORED DEATHS 10 TERMINAL 35 |
| |
| UNCENSORED DEATHS |
| 113 156 551 565 582 597 606 641 646 661 |
| 671 680 692 701 704 |
| CENSORED DEATHS |
| 457 457 457 457 457 457 457 457 457 457 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 729 DAYS
==================================================================================
| KAPLAN-MEIER SURVIVAL PROBABILITY ESTIMATES (%) |
| |
|--------------------------------------------------------------------------------|
| DOSE TIME (DAYS) |
| 90 180 270 365 425 485 545 605 665 729 (A) |
| |
|--------------------------------------------------------------------------------|
| | |
|0 PPM | 100.0 100.0 100.0 100.0 95.0 95.0 93.0 89.1 85.1 79.2 |
| | |
| | |
|250 PPM | 100.0 100.0 100.0 100.0 100.0 98.3 96.3 90.3 88.3 76.2 |
| | |
| | |
|500 PPM | 98.3 98.3 98.3 98.3 98.3 98.3 96.3 92.3 82.3 72.2 |
| | |
| | |
|1000 PPM | 100.0 96.7 96.7 96.7 96.7 96.7 96.7 88.6 80.6 70.5 |
| | |
| | |
==================================================================================
==================================================================================
| SURVIVAL SUMMARY STATISTICS |
| |
| |
|--------------------------------------------------------------------------------|
| DOSE |
| |
| 0 PPM 250 PPM 500 PPM 1000 PPM |
| |
|--------------------------------------------------------------------------------|
|SURVIVAL AT END OF STUDY| 79.2% 76.2% 72.2% 70.5% |
|(KAPLAN-MEIER) | |
| | |
|SIGNIFICANCE (B) | P=0.346 P=1.000 P=0.651 P=0.468 |
|(LIFE TABLE) | |
| | |
|MEAN DAY OF | 561.6 635.5 603.2 571.1 |
|NATURAL DEATHS (C) | (40.8) (24.2) (44.1) (47.5) |
|(STANDARD ERROR) | |
| | |
|MEAN LIFE SPAN (D) | 657.5 660.1 654.3 644.2 |
|(STANDARD ERROR) | (15.5) (15.8) (16.6) (18.1) |
| | |
==================================================================================
(A) FIRST TERMINAL SACRIFICE
(B) THE FIRST ENTRY IS THE TREND TEST (TARONE, 1975) RESULT.
SUBSEQUENT ENTRIES ARE THE RESULTS OF PAIRWISE TESTS
(COX,1972). NEGATIVE TRENDS ARE INDICATED BY "N".
(C) MEAN OF ALL UNCENSORED DEATHS PRIOR TO TERMINAL SACRIFICE
(D) MEAN OF ALL DEATHS (UNCENSORED, CENSORED, TERMINAL SACRIFICE)
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
KAPLAN-MEIER SURVIVAL CURVES
0 PPM = 1
250 PPM = 2
500 PPM = 3
1000 PPM = 4
------------------------------------------------------ SPECIES=MICE SEX=MALE -------------------------------------------------------
Plot of SURVIVAL*WEEK. Symbol is value of DOSE.
|
|
100 + 1 2 1 4 3
|
|
|
98 + 2 1 4 1 4 3 3
|
|
|
P 96 + 2 2 1 4 1 4
E |
R |
C |
E 94 + 2 2 4 4
N |
T |
|
S 92 + 2 2 1 1 4 4
U |
R |
V |
I 90 + 2 2 4 4
V |
A |
L |
88 + 2 11
|
|
|
86 + 21 1
|
|
|
84 + 1 1
|
--+----------+----------+----------+----------+----------+----------+----------+----------+----------+----------+----------+--
0 10 20 30 40 50 60 70 80 90 100 110
WEEK
NOTE: 8 obs hidden.
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
KAPLAN-MEIER SURVIVAL CURVES
0 PPM = 1
250 PPM = 2
500 PPM = 3
1000 PPM = 4
----------------------------------------------------- SPECIES=MICE SEX=FEMALE ------------------------------------------------------
Plot of SURVIVAL*WEEK. Symbol is value of DOSE.
|
|
100 + 1 3 4 1 2
| 3 4 4 2 3 2
|
| 4 1 1 3 2 4 3 2
P 95 + 1 1 4 4
E | 3 22
R | 1 1 4 3 3
C | 1 4 14
E 90 + 2 33 2
N | 1441 3 3 22
T | 11
| 4 4 22
S 85 + 1 44 1
U | 3 3 2 211
R | 4 3 3 22
V | 1 1
I 80 + 4433 2 2
V | 4 3 3 21 1
A |
L | 44 2 2
75 + 4 4
| 3 3
| 3 3
|
70 + 4 4
|
--+----------+----------+----------+----------+----------+----------+----------+----------+----------+----------+----------+--
0 10 20 30 40 50 60 70 80 90 100 110
WEEK
NOTE: 8 obs hidden.
NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Columbus 4,4 THIOBIS-(6-T-BUTYL-M-CRESOL) DATE: 11/09/95
EXPERIMENT: 05165 TEST: 04 TIME: 21:11:17
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE PAGE: 1
CONT: N01-ES-65156 ROUTE: DOSED FEED NTP C#: 61610B
PATHOLOGIST: J. TOFT CAS: 96-69-5
------------------------------------------------------------------------------------------------------------------------------------
REASONS FOR REMOVAL: ALL
REMOVAL DATE RANGE: ALL
TREATMENT GROUPS: INCLUDE ALL
NTP STATISTICAL ANALYSIS OF SURVIVAL DATA REPORT: PEIRPT11
LAB: Battelle Columbus 4,4 THIOBIS-(6-T-BUTYL-M-CRESOL) DATE: 11/09/95
EXPERIMENT: 05165 TEST: 04 TIME: 21:11:17
TEST TYPE: CHRONIC CAGES FROM 0000 TO LAST CAGE
CONT: N01-ES-65156 ROUTE: DOSED FEED NTP C#: 61610B
PATHOLOGIST: J. TOFT CAS: 96-69-5
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 0 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 274 274 274 274 274 274 274 274 274 274 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 250 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 274 274 274 274 274 274 274 274 274 274 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 500 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 274 274 274 274 274 274 274 274 274 274 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 1000 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 155 274 274 274 274 274 274 274 274 274 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
MALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
==================================================================================
| KAPLAN-MEIER SURVIVAL PROBABILITY ESTIMATES (%) |
| |
|--------------------------------------------------------------------------------|
| DOSE TIME (DAYS) |
| 90 180 270 365 425 485 545 605 665 1E5 (A) |
| |
|--------------------------------------------------------------------------------|
| | |
|0 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU| |
| | |
|250 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
|500 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
|1000 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
==================================================================================
==================================================================================
| SURVIVAL SUMMARY STATISTICS |
| |
| |
|--------------------------------------------------------------------------------|
| DOSE |
| |
| 0 250 500 1000 |
| PPM HCU PPM HCU PPM HCU PPM HCU|
|--------------------------------------------------------------------------------|
|SURVIVAL AT END OF STUDY| 100.0% 100.0% 100.0% 100.0% |
|(KAPLAN-MEIER) | |
| | |
|SIGNIFICANCE (B) | ----- ----- ----- ----- |
|(LIFE TABLE) | |
| | |
|MEAN DAY OF | . . . . |
|NATURAL DEATHS (C) | ( . ) ( . ) ( . ) ( . ) |
|(STANDARD ERROR) | |
| | |
|MEAN LIFE SPAN (D) | 183.3 183.3 183.3 177.3 |
|(STANDARD ERROR) | (20.8) (20.8) (20.8) (20.3) |
| | |
==================================================================================
(A) FIRST TERMINAL SACRIFICE
(B) THE FIRST ENTRY IS THE TREND TEST (TARONE, 1975) RESULT.
SUBSEQUENT ENTRIES ARE THE RESULTS OF PAIRWISE TESTS
(COX,1972). NEGATIVE TRENDS ARE INDICATED BY "N".
(C) MEAN OF ALL UNCENSORED DEATHS PRIOR TO TERMINAL SACRIFICE
(D) MEAN OF ALL DEATHS (UNCENSORED, CENSORED, TERMINAL SACRIFICE)
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 0 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 275 275 275 275 275 275 275 275 275 275 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 250 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 275 275 275 275 275 275 275 275 275 275 |
| |
|--------------------------------------------------------------------------------|
| DOSE = 500 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 275 275 275 275 275 275 275 275 275 275 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
INDIVIDUAL SURVIVAL TIMES (DAYS)
==================================================================================
| DOSE = 1000 PPM HCU |
| ---------------------------- |
| |
| TOTAL 20 UNCENSORED DEATHS 0 CENSORED DEATHS 20 TERMINAL 0 |
| |
| UNCENSORED DEATHS |
| NONE |
| CENSORED DEATHS |
| 92 92 92 92 92 93 93 93 93 93 |
| 275 275 275 275 275 275 275 275 275 275 |
| |
==================================================================================
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
STATISTICAL ANALYSIS OF SURVIVAL DATA
FEMALE MICE
FIRST TERMINAL SACRIFICE AT 99999 DAYS
==================================================================================
| KAPLAN-MEIER SURVIVAL PROBABILITY ESTIMATES (%) |
| |
|--------------------------------------------------------------------------------|
| DOSE TIME (DAYS) |
| 90 180 270 365 425 485 545 605 665 1E5 (A) |
| |
|--------------------------------------------------------------------------------|
| | |
|0 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU| |
| | |
|250 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
|500 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
|1000 | 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 100.0 |
|PPM HCU | |
| | |
==================================================================================
==================================================================================
| SURVIVAL SUMMARY STATISTICS |
| |
| |
|--------------------------------------------------------------------------------|
| DOSE |
| |
| 0 250 500 1000 |
| PPM HCU PPM HCU PPM HCU PPM HCU|
|--------------------------------------------------------------------------------|
|SURVIVAL AT END OF STUDY| 100.0% 100.0% 100.0% 100.0% |
|(KAPLAN-MEIER) | |
| | |
|SIGNIFICANCE (B) | ----- ----- ----- ----- |
|(LIFE TABLE) | |
| | |
|MEAN DAY OF | . . . . |
|NATURAL DEATHS (C) | ( . ) ( . ) ( . ) ( . ) |
|(STANDARD ERROR) | |
| | |
|MEAN LIFE SPAN (D) | 183.8 183.8 183.8 183.8 |
|(STANDARD ERROR) | (20.9) (20.9) (20.9) (20.9) |
| | |
==================================================================================
(A) FIRST TERMINAL SACRIFICE
(B) THE FIRST ENTRY IS THE TREND TEST (TARONE, 1975) RESULT.
SUBSEQUENT ENTRIES ARE THE RESULTS OF PAIRWISE TESTS
(COX,1972). NEGATIVE TRENDS ARE INDICATED BY "N".
(C) MEAN OF ALL UNCENSORED DEATHS PRIOR TO TERMINAL SACRIFICE
(D) MEAN OF ALL DEATHS (UNCENSORED, CENSORED, TERMINAL SACRIFICE)
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
KAPLAN-MEIER SURVIVAL CURVES
0 PPM HCU = 1
250 PPM HCU = 2
500 PPM HCU = 3
1000 PPM HCU = 4
------------------------------------------------------ SPECIES=MICE SEX=MALE -------------------------------------------------------
Plot of SURVIVAL*WEEK. Symbol is value of DOSE.
(NOTE: 6 obs hidden.)
P |
E |
R 200 +
C |
E |
N |
T 100 + 1 1
|
S |
U |
R 0 +
V |
I ---+----------------------------------------------------------------------------------+--
V 0 40
A
WEEK
4,4 THIOBIS-(6-T-BUTYL-M-CRESOL)
KAPLAN-MEIER SURVIVAL CURVES
0 PPM HCU = 1
250 PPM HCU = 2
500 PPM HCU = 3
1000 PPM HCU = 4
----------------------------------------------------- SPECIES=MICE SEX=FEMALE ------------------------------------------------------
Plot of SURVIVAL*WEEK. Symbol is value of DOSE.
(NOTE: 6 obs hidden.)
P |
E |
R 200 +
C |
E |
N |
T 100 + 1 1
|
S |
U |
R 0 +
V |
I ---+----------------------------------------------------------------------------------+--
V 0 40
A
WEEK