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TDMS Study 05704-02 Pathology Tables

NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97
Route: GAVAGE                                                                                                     Time: 08:29:59




       Facility:  International Research and Development Corp.

       Chemical CAS #:  108-46-3

       Lock Date:  None

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All






































                                                              Page   1

NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |             X                                                            |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  M  +  +  +  +  +|             
      Parasite Metazoan                    |                      X           X                                X     X|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                         X                          X                     |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Erosion, Multifocal                  |                                                                          |             
      Hyperplasia, Diffuse, Glandular      |                                                                         4|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Diffuse                 |                                                                          |             
      Inflammation, Chronic, Focal         |                         2                                                |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                     3                                    |             
      Basophilic Focus                     |                      X                 X                             X   |             
      Basophilic Focus, Multiple           |       X                          X                 X                     |             
      Clear Cell Focus                     |                X                       X                                 |             
      Clear Cell Focus, Multiple           |             X        X           X                                       |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Degeneration, Cystic, Focal          |                                                                          |             
      Eosinophilic Focus                   |             2                                                            |             
      Fatty Change, Focal                  |                                                                          |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Hemorrhage, Focal                    |                                                 2                        |             
      Hepatodiaphragmatic Nodule           |          X                                                           X   |             
      Hyperplasia, Focal                   |    2                                                                     |             
      Inflammation, Chronic, Multifocal    |             2                             2                              |             
      Mixed Cell Focus                     |                                                                          |             
      Vacuolization Cytoplasmic, Diffuse   |                                                                          |             
      Bile Duct, Hyperplasia               |    2  3  3  3     3  2  4  4     3  4  2  2        3  2     2  1  2  2  3|             
      Centrilobular, Fatty Change          |    2     3                 3                          3  3     1         |             
      Centrilobular, Necrosis              |                                                 4                        |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                        +                             +   |             
      Fat, Necrosis                        |                                        4                                 |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Atrophy, Diffuse                     |    2                                                                     |             
      Atrophy, Focal                       |       1     1           1              2                 2     1         |             
      Atrophy, Multifocal                  |          2           2     3     1  2     2     1     2                 2|             
      Artery, Inflammation, Chronic        |    2                                                                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   2                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Duct, Ectasia, Focal                 |                                                                          |             
      Interlobular, Edema, Diffuse         |    3                                                                     |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Multifocal              |                                                                         3|             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Erosion, Multifocal                  |                                                                         3|             
      Hyperplasia, Diffuse, Squamous       |                                                                         3|             
      Hyperplasia, Focal, Squamous         |                                                                          |             
      Inflammation, Chronic                |                                                       4                 4|             
      Ulcer, Focal                         |          3                                                               |             
      Ulcer, Multifocal                    |                                                       3                  |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Erosion, Focal                       |                                                 1        1               |             
      Erosion, Multifocal                  |                                                                         2|             
      Hemorrhage, Focal                    |             2                                                            |             
      Hyperplasia, Focal, Glandular        |             2                                                            |             
      Inflammation, Chronic                |    3                                                                     |             
      Mineralization, Diffuse              |    3                                                                     |             
      Ulcer, Focal                         |          2                                                               |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         |    3                 2                                2           2      |             
      Inflammation, Chronic, Multifocal    |             2  3                       2                                2|             
      Mineralization, Multifocal           |    2                                                                     |             
      Atrium, Thrombosis                   |                            X                                             |             
      Epicardium, Inflammation, Chronic,   |                                                                          |             
           Diffuse                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |                                                                          |             
      Congestion                           |                                                                          |             
      Cytoplasmic Alteration, Focal        |                                        1           2                     |             
      Cytoplasmic Alteration, Multifocal   |                                                                          |             
      Degeneration, Fatty, Focal           |                1                                                  2      |             
      Degeneration, Fatty, Multifocal      |                                                                         2|             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Hyperplasia, Focal                   |    2        3     2                             3  2  2                  |             
      Hyperplasia, Multifocal              |                                     3                                    |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   3                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Hypertrophy, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                                        2           3                    2|             
      Hyperplasia, Multifocal              |                                                                          |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |       1                                                                  |             
      Hyperplasia, Focal                   |                                                                         2|             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +  M  +  M  +  +     +  M  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Diffuse                 |    4                                                                    4|             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Pars Distalis, Angiectasis, Focal    |                                                                          |             
      Pars Distalis, Congestion            |                                                                          |             
      Pars Distalis, Cyst                  |                   X                                X              X      |             
      Pars Distalis, Hyperplasia, Focal    |    2  2              2  2           3                             2      |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                         3|             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +  A  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      C-Cell, Hyperplasia, Focal           |    4     1                          2              1                     |             
      C-Cell, Hyperplasia, Multifocal      |                                                                          |             
      Follicular Cell, Depletion Secretory |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Inflammation, Acute                  |                            3                                             |             
                                            __________________________________________________________________________|             
   Penis                                   |                            +                                             |             
      Concretion                           |                            4                                             |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Abscess                              |                                                                          |             
      Atrophy                              |                            4                                             |             
      Cyst                                 |          X                                                     X         |             
      Hyperplasia, Multifocal              |       1                             2                                    |             
      Inflammation, Chronic, Focal         |                                                                   2      |             
      Inflammation, Chronic, Multifocal    |       2  3  3     2  2  2  3     3     2  1        2  2              2  1|             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                                                       4                  |             
      Hyperplasia, Multifocal              |                                                                          |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
      Inflammation, Chronic, Focal         |             2                                         3                  |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   4                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                                +         |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Mineralization, Multifocal           |                                                                          |             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |    3  2  2        2     3  2           2  1     3                 3  3  3|             
      Seminiferous Tubule, Degeneration    |    4  3           3     4  4           4        4        4           4  4|             
      Serosa, Necrosis, Focal              |    4                                                                     |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Crystals, Multifocal                 |                                                                          |             
      Mineralization, Multifocal           |                                                                          |             
      Erythroid Cell, Proliferation        |                                     3           4        3           3  3|             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                                                          |             
      Inguinal, Hyperplasia, Plasma Cell   |                                                 4                        |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |             
      Mediastinal, Inflammation,           |                                                                          |             
          Suppurative                      |                                                                          |             
      Mediastinal, Pigmentation            |                                                                      4   |             
      Pancreatic, Angiectasis              |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                                          3               |             
      Hemorrhage                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Developmental Malformation           |                                                                          |             
      Fibrosis, Focal                      |                                        3        2                        |             
      Fibrosis, Multifocal                 |                                  3                                       |             
      Hematopoietic Cell Proliferation     |                                                 3        4           3   |             
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  +  +  I  +  +  +  +     +  +  I  +     M  +  +  +  +  +  +  +  +|             
      Cyst                                 |          X                                                              X|             
      Hemorrhage                           |                                  1                                       |             
      Epithelial Cell, Hyperplasia, Focal  |    2                                                                     |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Galactocele                          |                                                 X     X              X   |             
      Mineralization, Multifocal           |    3                                                                     |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Fibrous Osteodystrophy               |    4                                                                    X|             
 _____________________________________________________________________________________________________________________|             
                                                             Page   5                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
      Cranium, Hyperostosis                |                                                                          |             
      Trabecula, Hyperostosis, Multifocal  |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                  +                                   +   |             
      Abdominal, Necrosis, Focal           |                                  4                                       |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           |                      3  3           2                                    |             
      Edema, Focal                         |                                                                   2      |             
      Mineralization, Multifocal           |    1                                                                     |             
      Alveolar Epithelium, Hyperplasia,    |                                                                          |             
           Focal                           |                                                 2                        |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Focal                           |                                     1                                   1|             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Foreign Body                         |                                  3                    1                  |             
      Fungus                               |                                  X  X     X                              |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Chronic                |             2                    3  2                 2                  |             
      Inflammation, Suppurative            |                                           3                              |             
      Mucosa, Thrombosis, Multifocal       |                                                          X               |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                      3                                                   |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |                                                                          |             
      Olfactory Epithelium, Metaplasia     |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell                             |                                                                          |             
      Epithelium, Metaplasia               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +           +                          +                    +         |             
      Ectopic Tissue, Multifocal           |    X                                                                     |             
      Lens, Cataract                       |                                                                          |             
      Retina, Degeneration                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   6                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 5| 7| 6| 7| 5| 7| 7| 7| 6| 4| 7| 7| 7| 3| 4| 6| 7| 6| 6| 2| 2| 4| 6| 7|             
                             DAY ON TEST   | 5| 5| 2| 7| 2| 6| 3| 2| 2| 6| 5| 3| 2| 2| 8| 5| 9| 3| 1| 4| 8| 8| 9| 5| 3|             
                                           | 6| 8| 9| 7| 9| 3| 0| 9| 9| 0| 6| 0| 9| 9| 4| 6| 2| 0| 0| 4| 7| 7| 9| 7| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4| 5| 5| 5| 5| 5|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Hyperplasia, Multifocal, Tubular     |                                     1                                    |             
      Necrosis, Acute, Focal               |          3                                                               |             
      Nephropathy, Chronic                 |    4  3  2  2  1  2  3  3  4     2  3  4  1     3  3  4  2        2  2  4|             
      Pigmentation, Diffuse                |                                                                          |             
      Cortex, Mineralization, Multifocal   |    4                                                                     |             
      Papilla, Transitional Epithelium,    |                                                                          |             
           Hyperplasia                     |    3                                                                     |             
      Pelvis, Inflammation, Chronic        |                                                       3                  |             
      Pelvis, Mineralization               |                                                                      1   |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Degeneration, Hyaline           |                                                          4               |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +  +  +  +  +  +     +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Concretion                           |                                                             2            |             
      Cyst                                 |                                                                          |             
      Inflammation, Chronic, Diffuse       |                                                       2        3         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   7                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +        A  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +        A  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                                        X                                 |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +        M  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Parasite Metazoan                    |                         X  X                    X     X        X         |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +        A  +  +           A  +  +  +  +  +  +     +  +  +  +|             
      Erosion, Multifocal                  |                                                                      2   |             
      Hyperplasia, Diffuse, Glandular      |                                                                      4   |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +        A  +  +           A  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +        A  +  +           A  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Diffuse                 |                                                                      4   |             
      Inflammation, Chronic, Focal         |                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Angiectasis, Focal                   |                                                    2                     |             
      Basophilic Focus                     |             X              X                       X                     |             
      Basophilic Focus, Multiple           |       X                 X                 X  X  X        X     X         |             
      Clear Cell Focus                     |    X                                                                     |             
      Clear Cell Focus, Multiple           |       X                                         X        X     X         |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Degeneration, Cystic, Focal          |                            2                                             |             
      Eosinophilic Focus                   |                                                                          |             
      Fatty Change, Focal                  |                                                                2         |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                              1                           |             
      Hemorrhage, Focal                    |                                                                          |             
      Hepatodiaphragmatic Nodule           |                                                 X                        |             
      Hyperplasia, Focal                   |                                                                          |             
      Inflammation, Chronic, Multifocal    |                                           2                              |             
      Mixed Cell Focus                     |                                                                          |             
      Vacuolization Cytoplasmic, Diffuse   |                                                                          |             
      Bile Duct, Hyperplasia               |    2  3  4  3        2  4  1           3  3  2  3     3        4  3  3  2|             
      Centrilobular, Fatty Change          |          2                             2              2           3  3   |             
      Centrilobular, Necrosis              |          3                                                               |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                              +                           |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +        +  +  +           A  +  +  +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |                                                                          |             
      Atrophy, Focal                       |       1  2  2              1                       3  3                 1|             
      Atrophy, Multifocal                  |                         3                       2        4     1  3      |             
      Artery, Inflammation, Chronic        |                                                       2                  |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   8                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Duct, Ectasia, Focal                 |                                                                         2|             
      Interlobular, Edema, Diffuse         |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Multifocal              |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +        A  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Erosion, Multifocal                  |                                                                          |             
      Hyperplasia, Diffuse, Squamous       |                                                                      4   |             
      Hyperplasia, Focal, Squamous         |                                                       3                  |             
      Inflammation, Chronic                |                                                       3           4  4   |             
      Ulcer, Focal                         |                                                                         2|             
      Ulcer, Multifocal                    |                                                                      4   |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +        A  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Erosion, Focal                       |                         2                                            1   |             
      Erosion, Multifocal                  |                                                                          |             
      Hemorrhage, Focal                    |                                                                          |             
      Hyperplasia, Focal, Glandular        |                            3                                             |             
      Inflammation, Chronic                |                                                                          |             
      Mineralization, Diffuse              |                                                                          |             
      Ulcer, Focal                         |                                                                   3      |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                   +      |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Chronic, Focal         |                                        2                                2|             
      Inflammation, Chronic, Multifocal    |       2                    2              2  2                    2  3   |             
      Mineralization, Multifocal           |                                                                          |             
      Atrium, Thrombosis                   |          X                                                               |             
      Epicardium, Inflammation, Chronic,   |                                                                          |             
           Diffuse                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Angiectasis                          |                                                                          |             
      Congestion                           |                                                                      3   |             
      Cytoplasmic Alteration, Focal        |                                                 2                        |             
      Cytoplasmic Alteration, Multifocal   |                                                          2               |             
      Degeneration, Fatty, Focal           |       1              2                 2     2     1  1                  |             
      Degeneration, Fatty, Multifocal      |                                                                      2   |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Hyperplasia, Focal                   |       2                 2  2                       2                     |             
      Hyperplasia, Multifocal              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page   9                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      Hypertrophy, Focal                   |                                                       1                  |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +        +  +  +           +  +  +  M  +  +  +     +  +  +  +|             
      Hyperplasia, Focal                   |                      2     3                          2                  |             
      Hyperplasia, Multifocal              |    2                                      2                              |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +        +  +  +           A  +  +  +  +  +  +     +  +  +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Hyperplasia, Focal                   |       2                                                                  |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +        +  +  +           +  +  +  +  +  +  M     +  +  +  +|             
      Hyperplasia, Diffuse                 |                                                                          |             
      Hyperplasia, Focal                   |                                                                2         |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Pars Distalis, Angiectasis, Focal    |                      1                                                   |             
      Pars Distalis, Congestion            |                                        3                                 |             
      Pars Distalis, Cyst                  |                                                 X                        |             
      Pars Distalis, Hyperplasia, Focal    |                                              2                           |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      C-Cell, Hyperplasia, Focal           |       1                    3                    1  3                     |             
      C-Cell, Hyperplasia, Multifocal      |                                           1           1        2         |             
      Follicular Cell, Depletion Secretory |                                        4                                 |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Atrophy, Diffuse                     |                                        3                                 |             
      Inflammation, Acute                  |                                                                         2|             
                                            __________________________________________________________________________|             
   Penis                                   |                                                                          |             
      Concretion                           |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Abscess                              |                                                                          |             
      Atrophy                              |                                                                          |             
      Cyst                                 |                         X                                                |             
      Hyperplasia, Multifocal              |                                                                          |             
      Inflammation, Chronic, Focal         |                                                                          |             
      Inflammation, Chronic, Multifocal    |       3     2           2  2              2  2     2  2  2     2        2|             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Hyperplasia, Focal                   |             1                                            2               |             
      Hyperplasia, Multifocal              |                            3                                             |             
      Inflammation, Acute, Focal           |          3                                                               |             
      Inflammation, Chronic, Diffuse       |                      4                                                   |             
      Inflammation, Chronic, Focal         |       2                                   3  2                 2     2   |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  10                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Mineralization, Multifocal           |                                              1        2                  |             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |       2  2           3  2  2           2     2     3  2        2     1  2|             
      Seminiferous Tubule, Degeneration    |    4        4        3  4  4           2  2  4        4        4     4  4|             
      Serosa, Necrosis, Focal              |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Crystals, Multifocal                 |                                              3                           |             
      Mineralization, Multifocal           |                                              3                           |             
      Erythroid Cell, Proliferation        |                                              4        3                  |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Congestion                           |                                                                          |             
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |             
      Mediastinal, Hyperplasia, Plasma Cell|                                                                          |             
      Mediastinal, Inflammation,           |                                                                          |             
          Suppurative                      |                                                                          |             
      Mediastinal, Pigmentation            |                                                                          |             
      Pancreatic, Angiectasis              |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Congestion                           |                                                                          |             
      Hemorrhage                           |                                                    2                     |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Developmental Malformation           |                                                                          |             
      Fibrosis, Focal                      |       1                                                              4   |             
      Fibrosis, Multifocal                 |                                                                          |             
      Hematopoietic Cell Proliferation     |                                              4                           |             
      Pigmentation, Diffuse, Hemosiderin   |                      4                                                   |             
                                            __________________________________________________________________________|             
   Thymus                                  |    M  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Cyst                                 |                                                                          |             
      Hemorrhage                           |                                                                          |             
      Epithelial Cell, Hyperplasia, Focal  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  I  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Galactocele                          |                                                    X     X               |             
      Mineralization, Multifocal           |                                                                          |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Fibrous Osteodystrophy               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  11                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM - cont             |                                                                          |             
                                           |                                                                          |             
      Cranium, Hyperostosis                |                                                                          |             
      Trabecula, Hyperostosis, Multifocal  |                                              X                           |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
      Abdominal, Necrosis, Focal           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Inflammation, Chronic, Focal         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Congestion                           |             2        3                                                   |             
      Edema, Focal                         |                                                                          |             
      Mineralization, Multifocal           |                                                                          |             
      Alveolar Epithelium, Hyperplasia,    |                                                                          |             
           Focal                           |                                                                2         |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Focal                           |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +           +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Foreign Body                         |                                        1                                 |             
      Fungus                               |                                        X                                 |             
      Inflammation, Acute                  |                                        3                                 |             
      Inflammation, Chronic                |                                                                          |             
      Inflammation, Suppurative            |                                                                          |             
      Mucosa, Thrombosis, Multifocal       |          4                                                               |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |       2                                                                  |             
      Olfactory Epithelium, Metaplasia     |          3                                                               |             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell                             |                                                                         2|             
      Epithelium, Metaplasia               |          4                                                               |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |                                                       +                  |             
      Ectopic Tissue, Multifocal           |                                                                          |             
      Lens, Cataract                       |                                                                          |             
      Retina, Degeneration                 |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Congestion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  12                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 7| 7| 5| 7| 4| 4| 6| 7| 7| 4| 4| 4| 5| 7| 4| 7| 7| 6| 7| 4| 7| 6| 7| 6|             
                             DAY ON TEST   | 5| 3| 3| 6| 2| 5| 5| 4| 3| 3| 5| 5| 5| 8| 2| 7| 3| 3| 2| 2| 5| 2| 5| 2| 9|             
                                           | 6| 0| 0| 9| 9| 6| 6| 2| 0| 0| 6| 6| 6| 5| 9| 8| 0| 0| 9| 9| 6| 9| 2| 8| 4|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1|             
    CONTROL                                | 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|             
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM - cont                     |                                                                          |             
                                           |                                                                          |             
      Hyperplasia, Multifocal, Tubular     |                                                                          |             
      Necrosis, Acute, Focal               |                                                                          |             
      Nephropathy, Chronic                 |    3  3  2  3        2  3  3           2  3  2  3  4  1  2     3  2  4  3|             
      Pigmentation, Diffuse                |                                              4                           |             
      Cortex, Mineralization, Multifocal   |                                        1                                 |             
      Papilla, Transitional Epithelium,    |                                                                          |             
           Hyperplasia                     |                                                                          |             
      Pelvis, Inflammation, Chronic        |                                                                          |             
      Pelvis, Mineralization               |                                                                          |             
      Proximal Convoluted Renal Tubule,    |                                                                          |             
           Degeneration, Hyaline           |    2                                                                     |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +        +  +  +           +  +  +  +  +  +  +     +  +  +  +|             
      Concretion                           |                                                                          |             
      Cyst                                 |       X                                                                  |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  13                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | A  +  +  +  +  +  +  +  +  +                                             |  47        |
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +                                             |  47        |
      Parasite Metazoan                    |                X           X                                             |      7     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  M  +  +  +  +  +  +  +  +                                             |  47        |
      Parasite Metazoan                    |                X           X                                             |      9     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  +  +  +  +  +  +  +  +  +                                             |  47        |
      Erosion, Multifocal                  |                                                                          |      1  2.0|
      Hyperplasia, Diffuse, Glandular      |                                                                          |      2  4.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  +  +  +  +  +  +  +  A  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  +  +  +  +  +  +  +  A  +                                             |  46        |
      Hyperplasia, Diffuse                 |                                                                          |      1  4.0|
      Inflammation, Chronic, Focal         |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Angiectasis, Focal                   |                            2                                             |      3  2.3|
      Basophilic Focus                     |                X                                                         |      7     |
      Basophilic Focus, Multiple           |    X  X     X        X                                                   |     14     |
      Clear Cell Focus                     |       X  X                                                               |      5     |
      Clear Cell Focus, Multiple           |    X                                                                     |      8     |
      Cytoplasmic Alteration, Focal        |                   2                                                      |      1  2.0|
      Degeneration, Cystic, Focal          |                                                                          |      1  2.0|
      Eosinophilic Focus                   |                                                                          |      1  2.0|
      Fatty Change, Focal                  |                                                                          |      1  2.0|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      |                                                                          |      1  1.0|
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
      Hepatodiaphragmatic Nodule           |                            X                                             |      4     |
      Hyperplasia, Focal                   |                                                                          |      1  2.0|
      Inflammation, Chronic, Multifocal    |    2                                                                     |      4  2.0|
      Mixed Cell Focus                     |       2                                                                  |      1  2.0|
      Vacuolization Cytoplasmic, Diffuse   |                            3                                             |      1  3.0|
      Bile Duct, Hyperplasia               | 3  3  3  2  2  3  4  2  2  2                                             |     45  2.7|
      Centrilobular, Fatty Change          | 3           3           3                                                |     14  2.6|
      Centrilobular, Necrosis              | 3                                                                        |      3  3.3|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   3        |
      Fat, Necrosis                        |                                                                          |      1  4.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  14                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Atrophy, Diffuse                     |                                                                          |      1  2.0|
      Atrophy, Focal                       |          2              2                                                |     15  1.7|
      Atrophy, Multifocal                  | 4  2  2        1  2        2                                             |     20  2.2|
      Artery, Inflammation, Chronic        |                                                                          |      2  2.0|
      Duct, Ectasia, Focal                 |                                                                          |      1  2.0|
      Interlobular, Edema, Diffuse         |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hyperplasia, Multifocal              |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Erosion, Multifocal                  |                                                                          |      1  3.0|
      Hyperplasia, Diffuse, Squamous       |                                                                          |      2  3.5|
      Hyperplasia, Focal, Squamous         |             2                                                            |      2  2.5|
      Inflammation, Chronic                |                                                                          |      5  3.8|
      Ulcer, Focal                         |                                                                          |      2  2.5|
      Ulcer, Multifocal                    |                                                                          |      2  3.5|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Erosion, Focal                       |                                                                          |      4  1.3|
      Erosion, Multifocal                  |                                                                          |      1  2.0|
      Hemorrhage, Focal                    |                                                                          |      1  2.0|
      Hyperplasia, Focal, Glandular        |                                                                          |      2  2.5|
      Inflammation, Chronic                |                                                                          |      1  3.0|
      Mineralization, Diffuse              |                                                                          |      1  3.0|
      Ulcer, Focal                         |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |                                                                          |      6  2.2|
      Inflammation, Chronic, Multifocal    | 3  2  2     2                                                            |     14  2.2|
      Mineralization, Multifocal           |                                                                          |      1  2.0|
      Atrium, Thrombosis                   |                            X                                             |      3     |
      Epicardium, Inflammation, Chronic,   |                                                                          |            |
           Diffuse                         |                         2                                                |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +  I  +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  15                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Angiectasis                          |             2                                                            |      1  2.0|
      Congestion                           |                            2                                             |      2  2.5|
      Cytoplasmic Alteration, Focal        |                                                                          |      3  1.7|
      Cytoplasmic Alteration, Multifocal   |                                                                          |      1  2.0|
      Degeneration, Fatty, Focal           |       1                    2                                             |     10  1.5|
      Degeneration, Fatty, Multifocal      |                         1                                                |      3  1.7|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      | 1                                                                        |      1  1.0|
      Hyperplasia, Focal                   |                                                                          |     10  2.2|
      Hyperplasia, Multifocal              |       3                                                                  |      2  3.0|
      Hypertrophy, Focal                   |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Hyperplasia, Focal                   |             2                                                            |      7  2.3|
      Hyperplasia, Multifocal              |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Angiectasis, Focal                   |                                                                          |      1  1.0|
      Hyperplasia, Focal                   |             3                                                            |      3  2.3|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M  +  M  +  M  M  M  +  +  +                                             |  41        |
      Hyperplasia, Diffuse                 |                                                                          |      2  4.0|
      Hyperplasia, Focal                   |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Pars Distalis, Angiectasis, Focal    |                                                                          |      1  1.0|
      Pars Distalis, Congestion            |                                                                          |      1  3.0|
      Pars Distalis, Cyst                  |                X                                                         |      5     |
      Pars Distalis, Hyperplasia, Focal    |                         2                                                |      8  2.1|
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |                            3                                             |      2  3.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      C-Cell, Hyperplasia, Focal           |             1                                                            |      9  1.9|
      C-Cell, Hyperplasia, Multifocal      |       1                                                                  |      4  1.3|
      Follicular Cell, Depletion Secretory |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Atrophy, Diffuse                     |                                                                          |      1  3.0|
      Inflammation, Acute                  |                                                                          |      2  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  16                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Penis                                   |                                                                          |   1        |
      Concretion                           |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Abscess                              |             4                                                            |      1  4.0|
      Atrophy                              |                                                                          |      1  4.0|
      Cyst                                 |                                                                          |      3     |
      Hyperplasia, Multifocal              |                                                                          |      2  1.5|
      Inflammation, Chronic, Focal         |                            2                                             |      2  2.0|
      Inflammation, Chronic, Multifocal    | 2  2  2  2        2  2  1                                                |     32  2.1|
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Hyperplasia, Focal                   |       1                                                                  |      4  2.0|
      Hyperplasia, Multifocal              |                                                                          |      1  3.0|
      Inflammation, Acute, Focal           |                                                                          |      1  3.0|
      Inflammation, Chronic, Diffuse       |                                                                          |      1  4.0|
      Inflammation, Chronic, Focal         |                      2                                                   |      8  2.3|
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Mineralization, Multifocal           |                                                                          |      2  1.5|
      Interstitial Cell, Hyperplasia,      |                                                                          |            |
          Multifocal                       | 3     2     2        2  2  2                                             |     30  2.2|
      Seminiferous Tubule, Degeneration    | 4                    4  4  4                                             |     26  3.7|
      Serosa, Necrosis, Focal              |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Crystals, Multifocal                 |                                                                          |      1  3.0|
      Mineralization, Multifocal           |                                                                          |      1  3.0|
      Erythroid Cell, Proliferation        | 3                                                                        |      8  3.3|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           |                4                                                         |      1  4.0|
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |      1  4.0|
      Mediastinal, Hyperplasia, Plasma Cell|                            3                                             |      1  3.0|
      Mediastinal, Inflammation,           |                                                                          |            |
          Suppurative                      |                         3                                                |      1  3.0|
      Mediastinal, Pigmentation            |                                                                          |      1  4.0|
      Pancreatic, Angiectasis              |          2                                                               |      1  2.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      1  3.0|
      Hemorrhage                           |                         3                                                |      2  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  17                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Developmental Malformation           |                X                                                         |      1     |
      Fibrosis, Focal                      |                                                                          |      4  2.5|
      Fibrosis, Multifocal                 |                                                                          |      1  3.0|
      Hematopoietic Cell Proliferation     | 4  2                    3  2                                             |      8  3.1|
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +  +  +  +  +  +                                             |  46        |
      Cyst                                 |                                                                          |      2     |
      Hemorrhage                           | 2     3           3                                                      |      4  2.3|
      Epithelial Cell, Hyperplasia, Focal  |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +                                             |  49        |
      Galactocele                          |                                                                          |      5     |
      Mineralization, Multifocal           |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Fibrous Osteodystrophy               |                                                                          |      2  4.0|
      Cranium, Hyperostosis                | X                                                                        |      1     |
      Trabecula, Hyperostosis, Multifocal  |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         | +                                                                        |   3        |
      Abdominal, Necrosis, Focal           |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |                   3                                                      |      1  3.0|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      5  2.6|
      Edema, Focal                         |                                                                          |      1  2.0|
      Mineralization, Multifocal           |                                                                          |      1  1.0|
      Alveolar Epithelium, Hyperplasia,    |                                                                          |            |
           Focal                           |                                                                          |      2  2.0|
      Interstitium, Inflammation, Chronic, |                                                                          |            |
           Focal                           |                                                                          |      2  1.0|
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +  +  +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  18                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 6| 7| 7| 7| 7| 7| 7| 7| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 3| 3| 2| 2| 3| 2| 3| 2| 2|                                            |            |
                                           | 7| 0| 0| 9| 9| 0| 9| 0| 1| 9|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 1| 1| 1| 1| 1| 1| 1| 1| 1| 1|                                            |      A     |
    CONTROL                                | 1| 1| 1| 1| 1| 2| 2| 2| 2| 2|                                            |      L     |
    MALE                                   | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Foreign Body                         | 1                                                                        |      4  1.5|
      Fungus                               |                                                                          |      4     |
      Inflammation, Acute                  |                                                                          |      1  3.0|
      Inflammation, Chronic                |                                                                          |      4  2.3|
      Inflammation, Suppurative            | 2                                                                        |      2  2.5|
      Mucosa, Thrombosis, Multifocal       |                                                                          |      2  4.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Chronic                         |                                                                          |      1  3.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Suppurative                     |                                                                          |      1  2.0|
      Olfactory Epithelium, Metaplasia     |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell                             |                                                                          |      1  2.0|
      Epithelium, Metaplasia               |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |          +                                                               |   6        |
      Ectopic Tissue, Multifocal           |                                                                          |      1     |
      Lens, Cataract                       |          3                                                               |      1  3.0|
      Retina, Degeneration                 |          4                                                               |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           |                         3                                                |      1  3.0|
      Hyperplasia, Multifocal, Tubular     |                1                                                         |      2  1.0|
      Necrosis, Acute, Focal               |                                                                          |      1  3.0|
      Nephropathy, Chronic                 | 2  3  1  3  3  2  2  2  3  3                                             |     48  2.6|
      Pigmentation, Diffuse                |                                                                          |      1  4.0|
      Cortex, Mineralization, Multifocal   |                                                                          |      2  2.5|
      Papilla, Transitional Epithelium,    |                                                                          |            |
           Hyperplasia                     |                            2                                             |      2  2.5|
      Pelvis, Inflammation, Chronic        |                                                                          |      1  3.0|
      Pelvis, Mineralization               |                                                                          |      1  1.0|
      Proximal Convoluted Renal Tubule,    |                                                                          |            |
           Degeneration, Hyaline           |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +                                             |  50        |
      Concretion                           |                                                                          |      1  2.0|
      Cyst                                 |                                                                          |      1     |
      Inflammation, Chronic, Diffuse       |                                                                          |      2  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  19                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 5| 7| 7| 4| 7| 7| 7| 6| 6| 7| 6| 6| 3| 4| 7| 6| 6| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 2| 9| 2| 0| 5| 2| 3| 2| 5| 7| 2| 9| 5| 8| 5| 1| 3| 0| 2| 3| 2| 3| 3| 3|             
                                           | 2| 9| 6| 9| 8| 6| 9| 0| 9| 0| 9| 9| 2| 0| 0| 6| 4| 9| 1| 9| 0| 9| 0| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  A  +  A  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  A  +  A  +  +  +  +  +|             
      Parasite Metazoan                    |                                        X                                X|             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                                        X                 X               |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  A  +  A  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  A  +  A  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  A  +  A  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                                                   2      |             
      Basophilic Focus                     |                      X                                                   |             
      Basophilic Focus, Multiple           |    X     X  X           X                                   X  X        X|             
      Clear Cell Focus                     |    X        X        X           X                                X  X   |             
      Clear Cell Focus, Multiple           |                         X                                   X  X        X|             
      Congestion                           |                                                 3                        |             
      Cytoplasmic Alteration, Multifocal   |                                                                         3|             
      Degeneration, Cystic, Multifocal     |                                                                          |             
      Fatty Change, Focal                  |                   2                                                      |             
      Granuloma                            |                                                                          |             
      Hepatodiaphragmatic Nodule           |          X                                            X                 X|             
      Hyperplasia, Focal                   |             3     2                                                      |             
      Inflammation, Chronic, Multifocal    |          2                                1                    3     2   |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Hyperplasia               |    2  1  3  4     2  2  2  4  4  2  3  4  2     3  2  3     2  2  4  3  3|             
      Centrilobular, Fatty Change          |                                                                          |             
      Centrilobular, Necrosis              |                                                    4                     |             
      Periportal, Fatty Change             |       1                                                                  |             
                                            __________________________________________________________________________|             
   Mesentery                               |    +     +                                +                              |             
      Fat, Necrosis                        |          4                                3                              |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Atrophy, Focal                       |       1  2                                      1           1        1   |             
      Atrophy, Multifocal                  |                            3  4  2     3  2                             2|             
      Cyst                                 |                                                                          |             
      Hyperplasia, Focal                   |                         3                                                |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Atrophy, Focal                       |                                                                          |             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Erosion, Focal                       |                                                                          |             
      Hyperplasia, Focal, Squamous         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  20                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 5| 7| 7| 4| 7| 7| 7| 6| 6| 7| 6| 6| 3| 4| 7| 6| 6| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 2| 9| 2| 0| 5| 2| 3| 2| 5| 7| 2| 9| 5| 8| 5| 1| 3| 0| 2| 3| 2| 3| 3| 3|             
                                           | 2| 9| 6| 9| 8| 6| 9| 0| 9| 0| 9| 9| 2| 0| 0| 6| 4| 9| 1| 9| 0| 9| 0| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Inflammation, Acute                  |       4                                                                  |             
      Inflammation, Chronic                |                                                                          |             
      Ulcer, Focal                         |                                                                          |             
      Ulcer, Multifocal                    |       4                                                                  |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Ectopic Tissue                       |             X                                                            |             
      Erosion, Multifocal                  |                               3                                          |             
      Hyperplasia, Focal, Lymphoid         |                                                                          |             
      Inflammation, Acute                  |       3                                                                  |             
      Inflammation, Chronic                |                                     2                                    |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         | 3  2                    2     3                                          |             
      Inflammation, Chronic, Multifocal    |          3        2              2              3  3           2     2  2|             
      Atrium, Thrombosis                   |          X                                                               |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis                          |                                                                          |             
      Congestion                           |             3                                                            |             
      Cytoplasmic Alteration, Focal        |                   1                                                  2   |             
      Degeneration, Fatty, Focal           |                                                                         2|             
      Degeneration, Fatty, Multifocal      |       1                                                                  |             
      Granuloma                            |                                                                          |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                         2                                                |             
      Hyperplasia, Focal                   |             1              2           2                                 |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Atypia Nuclear                       |             2                                                            |             
      Hyperplasia, Focal                   |          2                    1                       1                 1|             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                         2                                      2         |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  +     +  +  M  +  +  +  +  +  +     +  +  M  +  M  M  M  +  +|             
      Hyperplasia, Focal                   |                      3                                                   |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |                                                                3         |             
      Pars Distalis, Cyst                  |                         X                                                |             
      Pars Distalis, Hyperplasia, Focal    |                         1                 2                             3|             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                          |             
      Pars Distalis, Infiltration Cellular,|                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  21                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 5| 7| 7| 4| 7| 7| 7| 6| 6| 7| 6| 6| 3| 4| 7| 6| 6| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 2| 9| 2| 0| 5| 2| 3| 2| 5| 7| 2| 9| 5| 8| 5| 1| 3| 0| 2| 3| 2| 3| 3| 3|             
                                           | 2| 9| 6| 9| 8| 6| 9| 0| 9| 0| 9| 9| 2| 0| 0| 6| 4| 9| 1| 9| 0| 9| 0| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
           Focal, Histiocyte               |                                                                   2      |             
      Pars Intermedia, Cyst                |                            X                                      X      |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      C-Cell, Hyperplasia, Focal           |       2                 1        2                                       |             
      C-Cell, Hyperplasia, Multifocal      |                                                                          |             
      Follicular Cell, Hyperplasia, Cystic,|                                                                          |             
           Focal                           |                                                                   2      |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Granuloma Sperm, Focal               |                                                                          |             
      Necrosis                             |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Dilatation                           |                                                                          |             
      Inflammation, Chronic, Focal         |                                           2              2               |             
      Inflammation, Chronic, Multifocal    | 3  2        2     2  3  2     2  2  3  2                    2     2  2  2|             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |          2  1              1                                      2  2   |             
      Hyperplasia, Multifocal              |                                                             2            |             
      Inflammation, Acute, Focal           |                                                                          |             
      Inflammation, Chronic, Focal         |                                        2                          3  3   |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         | +                                                                        |             
      Depletion Secretory                  | 4                                                                        |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |       2                       2     2  2  2           2  1        3      |             
      Seminiferous Tubule, Degeneration    | 2                 4           4     2                          4  4      |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Myelofibrosis, Focal                 |                                                                   2      |             
      Erythroid Cell, Proliferation        |             3                 4                    3                     |             
      Myeloid Cell, Proliferation          |                                     4                                    |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |             
      Popliteal, Hyperplasia, Lymphoid     |                                                 3                        |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Cyst, Multiple                       |                         X                                                |             
      Erythrophagocytosis                  |                                                                          |             
      Hyperplasia, Lymphoid                |                                                                          |             
      Sinus, Ectasia                       |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  22                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 5| 7| 7| 4| 7| 7| 7| 6| 6| 7| 6| 6| 3| 4| 7| 6| 6| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 2| 9| 2| 0| 5| 2| 3| 2| 5| 7| 2| 9| 5| 8| 5| 1| 3| 0| 2| 3| 2| 3| 3| 3|             
                                           | 2| 9| 6| 9| 8| 6| 9| 0| 9| 0| 9| 9| 2| 0| 0| 6| 4| 9| 1| 9| 0| 9| 0| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           |                                                                          |             
      Fibrosis, Diffuse                    |                               4                                          |             
      Fibrosis, Focal                      |                         3              2                                 |             
      Fibrosis, Multifocal                 |                                                                         3|             
      Hematocyst                           |                                     X                                    |             
      Hematopoietic Cell Proliferation     |                                                    3                     |             
      Metaplasia, Focal, Osseous           |                                                                          |             
      Pigmentation, Diffuse, Hemosiderin   | 3                                                                        |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  +  M     +  +  +  M  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Cyst                                 |                         X                                                |             
      Hemorrhage                           |                                           3        2                     |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Galactocele                          |                   X                                                      |             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Subcutaneous Tissue, Edema           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Congestion                           | 2                    2                          3                        |             
      Emphysema                            |                                           3                              |             
      Hemorrhage, Focal                    |             2                                                            |             
      Alveolar Epithelium, Hyperplasia,    |                                                                          |             
           Focal                           |                                                                          |             
      Alveolus, Infiltration Cellular,     |                                                                          |             
           Multifocal, Histiocyte          |                                                                          |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Focal                           |                   2                                                      |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Multifocal                      |                                                                          |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Diffuse                         |                                                       4                  |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Foreign Body                         |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
      Inflammation, Suppurative            |                                                    3                     |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  23                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 5| 7| 5| 7| 7| 4| 7| 7| 7| 6| 6| 7| 6| 6| 3| 4| 7| 6| 6| 6| 7| 7| 7| 7| 7|             
                             DAY ON TEST   | 3| 2| 9| 2| 0| 5| 2| 3| 2| 5| 7| 2| 9| 5| 8| 5| 1| 3| 0| 2| 3| 2| 3| 3| 3|             
                                           | 2| 9| 6| 9| 8| 6| 9| 0| 9| 0| 9| 9| 2| 0| 0| 6| 4| 9| 1| 9| 0| 9| 0| 0| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2| 2|             
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8| 9| 9| 9| 9| 9|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Metaplasia, Squamous                 |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         | 4                                                     4           2      |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Glands, Ectasia, Focal               |                                                                      2   |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     | +                          +                    +                        |             
      Anterior Chamber, Hemorrhage         |                                                 3                        |             
      Anterior Chamber, Iris, Posterior    |                                                                          |             
          Chamber, Inflammation            |                                                                          |             
      Cornea, Inflammation                 |                                                 3                        |             
      Lens, Cataract                       |                            3                    3                        |             
      Retina, Degeneration                 |                                                 4                        |             
                                            __________________________________________________________________________|             
   Lacrimal Gland                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Cyst                                 |          X              X                                                |             
      Hyperplasia, Multifocal, Tubular     |                                                 2                        |             
      Nephropathy, Chronic                 | 3  3  4  4  4     4  3  4  4  4  3  3  3  1     4  3  2  2  3  3  4  3  3|             
      Pigmentation, Diffuse                |                                                                          |             
      Cortex, Necrosis, Diffuse            |                                                                          |             
      Pelvis, Parasite Metazoan            |                                                 X                        |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +     +  +  +  +  +  +  +  +  +     +  +  +  +  +  +  +  +  +|             
      Concretion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  24                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 4| 5| 7| 6| 7| 7| 7| 7| 7| 7| 4| 4| 5| 7| 6| 4| 4| 4| 5| 5|             
                             DAY ON TEST   | 5| 1| 2| 2| 3| 5| 3| 2| 6| 1| 1| 3| 2| 3| 3| 5| 5| 6| 2| 2| 5| 5| 5| 6| 8|             
                                           | 6| 6| 9| 9| 0| 6| 2| 9| 6| 2| 9| 0| 9| 0| 0| 6| 6| 2| 9| 4| 6| 6| 6| 6| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Large                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Parasite Metazoan                    |       X                                   X                              |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Parasite Metazoan                    |       X     X                                                            |             
                                            __________________________________________________________________________|             
   Intestine Small                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Liver                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Angiectasis, Focal                   |                            2  2     2                                    |             
      Basophilic Focus                     |       X     X        X           X  X                    X               |             
      Basophilic Focus, Multiple           |                                        X  X           X                  |             
      Clear Cell Focus                     |          X  X                       X                 X                  |             
      Clear Cell Focus, Multiple           |       X              X           X     X  X                              |             
      Congestion                           |                                                                          |             
      Cytoplasmic Alteration, Multifocal   |                                                                          |             
      Degeneration, Cystic, Multifocal     |                      2                                                   |             
      Fatty Change, Focal                  |                                                                          |             
      Granuloma                            |                                                                          |             
      Hepatodiaphragmatic Nodule           |                                                                          |             
      Hyperplasia, Focal                   |                                  2                                       |             
      Inflammation, Chronic, Multifocal    |                                           2                              |             
      Necrosis, Focal                      |                                                                          |             
      Bile Duct, Hyperplasia               |    4  3  3  2     3  3  4  3  4  2  3  3  2        1  3  2           3  3|             
      Centrilobular, Fatty Change          |    2                                                                     |             
      Centrilobular, Necrosis              |                                                          1               |             
      Periportal, Fatty Change             |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                       +                 +|             
      Fat, Necrosis                        |                                                                         3|             
                                            __________________________________________________________________________|             
   Pancreas                                |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Atrophy, Focal                       |          4                    2  2                 2                    2|             
      Atrophy, Multifocal                  |    3  3                             2     2                          3   |             
      Cyst                                 |                                        X                                 |             
      Hyperplasia, Focal                   |                      4                                                   |             
                                            __________________________________________________________________________|             
   Salivary Glands                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Atrophy, Focal                       |                                                                          |             
      Hyperplasia, Focal                   |             1                                                            |             
                                            __________________________________________________________________________|             
   Stomach                                 |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Erosion, Focal                       |                                                    2                     |             
      Hyperplasia, Focal, Squamous         |                               2                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  25                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 4| 5| 7| 6| 7| 7| 7| 7| 7| 7| 4| 4| 5| 7| 6| 4| 4| 4| 5| 5|             
                             DAY ON TEST   | 5| 1| 2| 2| 3| 5| 3| 2| 6| 1| 1| 3| 2| 3| 3| 5| 5| 6| 2| 2| 5| 5| 5| 6| 8|             
                                           | 6| 6| 9| 9| 0| 6| 2| 9| 6| 2| 9| 0| 9| 0| 0| 6| 6| 2| 9| 4| 6| 6| 6| 6| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
      Inflammation, Acute                  |                                                    4                     |             
      Inflammation, Chronic                |                            2  2                                          |             
      Ulcer, Focal                         |                            3                                             |             
      Ulcer, Multifocal                    |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Ectopic Tissue                       |                                                                          |             
      Erosion, Multifocal                  |                                                          2               |             
      Hyperplasia, Focal, Lymphoid         |                            2                                             |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Tooth                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Inflammation, Chronic, Focal         |                                                                          |             
      Inflammation, Chronic, Multifocal    |       2  2  3              3     2     3  3                              |             
      Atrium, Thrombosis                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Angiectasis                          |                                        2                                 |             
      Congestion                           |                                                                          |             
      Cytoplasmic Alteration, Focal        |                            3        2                                    |             
      Degeneration, Fatty, Focal           |    2     2                 3        2                    1               |             
      Degeneration, Fatty, Multifocal      |                   2                                                      |             
      Granuloma                            |                                                                          |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                       2                  |             
      Hyperplasia, Focal                   |                            2        2                 3                  |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Atypia Nuclear                       |                                                                          |             
      Hyperplasia, Focal                   |                            3                                             |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       |    +  +  +  +     +  +  +  +  +  +  +  +  M        +  +  +           +  +|             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Pars Distalis, Cyst                  |       X              X                                                   |             
      Pars Distalis, Hyperplasia, Focal    |                                     2                                    |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                                                                          |             
      Pars Distalis, Infiltration Cellular,|                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  26                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 4| 5| 7| 6| 7| 7| 7| 7| 7| 7| 4| 4| 5| 7| 6| 4| 4| 4| 5| 5|             
                             DAY ON TEST   | 5| 1| 2| 2| 3| 5| 3| 2| 6| 1| 1| 3| 2| 3| 3| 5| 5| 6| 2| 2| 5| 5| 5| 6| 8|             
                                           | 6| 6| 9| 9| 0| 6| 2| 9| 6| 2| 9| 0| 9| 0| 0| 6| 6| 2| 9| 4| 6| 6| 6| 6| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
           Focal, Histiocyte               |                                                                          |             
      Pars Intermedia, Cyst                |                                                                          |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      C-Cell, Hyperplasia, Focal           |                                                                          |             
      C-Cell, Hyperplasia, Multifocal      |                                     1                 1                  |             
      Follicular Cell, Hyperplasia, Cystic,|                                                                          |             
           Focal                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Granuloma Sperm, Focal               |                                                                          |             
      Necrosis                             |                                                       4                  |             
                                            __________________________________________________________________________|             
   Preputial Gland                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Dilatation                           |                                  4                                       |             
      Inflammation, Chronic, Focal         |    1                                                                    3|             
      Inflammation, Chronic, Multifocal    |       3  2           3  3  2     4  2  2           2  2                  |             
                                            __________________________________________________________________________|             
   Prostate                                |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Hyperplasia, Focal                   |                      1  2              2                                 |             
      Hyperplasia, Multifocal              |                                                                          |             
      Inflammation, Acute, Focal           |                                                    2                     |             
      Inflammation, Chronic, Focal         |                            2           3                 2               |             
                                            __________________________________________________________________________|             
   Seminal Vesicle                         |                                                                          |             
      Depletion Secretory                  |                                                                          |             
                                            __________________________________________________________________________|             
   Testes                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |                   2           2     2                                1   |             
      Seminiferous Tubule, Degeneration    |    2                          4                          4               |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Myelofibrosis, Focal                 |                                                                          |             
      Erythroid Cell, Proliferation        |                               3                                      3   |             
      Myeloid Cell, Proliferation          |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node                              |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Inguinal, Hyperplasia, Plasma Cell   |                                                                          |             
      Popliteal, Hyperplasia, Lymphoid     |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Cyst, Multiple                       |                                                                          |             
      Erythrophagocytosis                  |                                                          2               |             
      Hyperplasia, Lymphoid                |                                                       4                  |             
      Sinus, Ectasia                       |          2                       2                                       |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  27                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 4| 5| 7| 6| 7| 7| 7| 7| 7| 7| 4| 4| 5| 7| 6| 4| 4| 4| 5| 5|             
                             DAY ON TEST   | 5| 1| 2| 2| 3| 5| 3| 2| 6| 1| 1| 3| 2| 3| 3| 5| 5| 6| 2| 2| 5| 5| 5| 6| 8|             
                                           | 6| 6| 9| 9| 0| 6| 2| 9| 6| 2| 9| 0| 9| 0| 0| 6| 6| 2| 9| 4| 6| 6| 6| 6| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Congestion                           |    4                                                                     |             
      Fibrosis, Diffuse                    |                                                                          |             
      Fibrosis, Focal                      |                                     3                                    |             
      Fibrosis, Multifocal                 |                                                                          |             
      Hematocyst                           |                                                                          |             
      Hematopoietic Cell Proliferation     |                                                          4               |             
      Metaplasia, Focal, Osseous           |                         2                                                |             
      Pigmentation, Diffuse, Hemosiderin   |                                                    2                     |             
                                            __________________________________________________________________________|             
   Thymus                                  |    +  +  +  +     +  +  I  +  +  +  +  +  +        +  +  +           +  +|             
      Cyst                                 |                                                                          |             
      Hemorrhage                           |                                                          3               |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Galactocele                          |                                        X           X                     |             
                                            __________________________________________________________________________|             
   Skin                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Subcutaneous Tissue, Edema           |                                                          4               |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Congestion                           |                                                                         3|             
      Emphysema                            |                                                                          |             
      Hemorrhage, Focal                    |                                                          1               |             
      Alveolar Epithelium, Hyperplasia,    |                                                                          |             
           Focal                           |                                                                          |             
      Alveolus, Infiltration Cellular,     |                                                                          |             
           Multifocal, Histiocyte          |                                                                          |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Focal                           |                                                                          |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Multifocal                      |                                                                      2   |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Diffuse                         |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  M           +  +|             
      Foreign Body                         |                      2                                                   |             
      Inflammation, Chronic                |                      3                                                   |             
      Inflammation, Suppurative            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  28                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 4| 6| 7| 7| 7| 4| 5| 7| 6| 7| 7| 7| 7| 7| 7| 4| 4| 5| 7| 6| 4| 4| 4| 5| 5|             
                             DAY ON TEST   | 5| 1| 2| 2| 3| 5| 3| 2| 6| 1| 1| 3| 2| 3| 3| 5| 5| 6| 2| 2| 5| 5| 5| 6| 8|             
                                           | 6| 6| 9| 9| 0| 6| 2| 9| 6| 2| 9| 0| 9| 0| 0| 6| 6| 2| 9| 4| 6| 6| 6| 6| 8|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|             
    112MG/KG                               | 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3| 4| 4| 4| 4| 4|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
      Metaplasia, Squamous                 |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Chronic                         |                                                                          |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
           Suppurative                     |                                                                         3|             
                                            __________________________________________________________________________|             
   Trachea                                 |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Glands, Ectasia, Focal               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |    +                                                                     |             
      Anterior Chamber, Hemorrhage         |                                                                          |             
      Anterior Chamber, Iris, Posterior    |                                                                          |             
          Chamber, Inflammation            |    2                                                                     |             
      Cornea, Inflammation                 |                                                                          |             
      Lens, Cataract                       |    3                                                                     |             
      Retina, Degeneration                 |    4                                                                     |             
                                            __________________________________________________________________________|             
   Lacrimal Gland                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Cyst                                 |       X     X                                                            |             
      Hyperplasia, Multifocal, Tubular     |                                                                          |             
      Nephropathy, Chronic                 |    2  3  2  3     3  3  3  4  3  3  4  2  3        2  3  2           2  3|             
      Pigmentation, Diffuse                |                                                                      3   |             
      Cortex, Necrosis, Diffuse            |                         4                                                |             
      Pelvis, Parasite Metazoan            |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         |    +  +  +  +     +  +  +  +  +  +  +  +  +        +  +  +           +  +|             
      Concretion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  29                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +     +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +     +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | A     +  +  +  +  +  A  +  +                                             |  46        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | A     +  +  +  +  +  +  +  +                                             |  47        |
      Parasite Metazoan                    |                            X                                             |      5     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | A     +  +  +  +  +  +  +  +                                             |  49        |
      Parasite Metazoan                    |                                                                          |      4     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +     +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | A     +  +  +  +  +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | A     +  +  +  +  +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | A     +  +  +  +  +  +  +  +                                             |  47        |
                                            __________________________________________________________________________|____________|
   Liver                                   | +     +  +  +  +  +  +  +  +                                             |  50        |
      Angiectasis, Focal                   |                                                                          |      4  2.0|
      Basophilic Focus                     |                         X                                                |      8     |
      Basophilic Focus, Multiple           |          X  X     X                                                      |     13     |
      Clear Cell Focus                     |                                                                          |     10     |
      Clear Cell Focus, Multiple           |             X                                                            |     10     |
      Congestion                           |                                                                          |      1  3.0|
      Cytoplasmic Alteration, Multifocal   |                                                                          |      1  3.0|
      Degeneration, Cystic, Multifocal     |                                                                          |      1  2.0|
      Fatty Change, Focal                  |                                                                          |      1  2.0|
      Granuloma                            |                1                                                         |      1  1.0|
      Hepatodiaphragmatic Nodule           |                                                                          |      3     |
      Hyperplasia, Focal                   |                                                                          |      3  2.3|
      Inflammation, Chronic, Multifocal    |       1                                                                  |      6  1.8|
      Necrosis, Focal                      | 1                                                                        |      1  1.0|
      Bile Duct, Hyperplasia               |       2     3  3  3  4  2  3                                             |     46  2.8|
      Centrilobular, Fatty Change          |                                                                          |      1  2.0|
      Centrilobular, Necrosis              |                                                                          |      2  2.5|
      Periportal, Fatty Change             |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                                                                          |   5        |
      Fat, Necrosis                        |                                                                          |      3  3.3|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +     +  +  +  +  +  +  +  +                                             |  50        |
      Atrophy, Focal                       |       2                                                                  |     11  1.8|
      Atrophy, Multifocal                  |          4  3     2  4  1                                                |     16  2.7|
      Cyst                                 |                                                                          |      1     |
      Hyperplasia, Focal                   |                                                                          |      2  3.5|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +     +  +  +  +  +  +  +  +                                             |  50        |
      Atrophy, Focal                       |                   2                                                      |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  30                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Hyperplasia, Focal                   |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +     +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +     +  +  +  +  +  +  +  +                                             |  50        |
      Erosion, Focal                       | 2                                                                        |      2  2.0|
      Hyperplasia, Focal, Squamous         |                                                                          |      1  2.0|
      Inflammation, Acute                  | 2                                                                        |      3  3.3|
      Inflammation, Chronic                |                                                                          |      2  2.0|
      Ulcer, Focal                         |                                                                          |      1  3.0|
      Ulcer, Multifocal                    |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +     +  +  +  +  +  +  +  +                                             |  50        |
      Ectopic Tissue                       |                                                                          |      1     |
      Erosion, Multifocal                  |                                                                          |      2  2.5|
      Hyperplasia, Focal, Lymphoid         |                                                                          |      1  2.0|
      Inflammation, Acute                  |                                                                          |      1  3.0|
      Inflammation, Chronic                |             2                                                            |      2  2.0|
                                            __________________________________________________________________________|____________|
   Tooth                                   |                         +                                                |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Heart                                   | +     +  +  +  +  +  +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |       2                                                                  |      5  2.4|
      Inflammation, Chronic, Multifocal    |          2  3     2     2                                                |     19  2.4|
      Atrium, Thrombosis                   |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +     +  +  +  +  +  +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +     +  +  +  +  +  +  +  +                                             |  50        |
      Angiectasis                          |                                                                          |      1  2.0|
      Congestion                           |                                                                          |      1  3.0|
      Cytoplasmic Alteration, Focal        |                                                                          |      4  2.0|
      Degeneration, Fatty, Focal           |                                                                          |      6  2.0|
      Degeneration, Fatty, Multifocal      |                                                                          |      2  1.5|
      Granuloma                            |             4                                                            |      1  4.0|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      |          2        2                                                      |      4  2.0|
      Hyperplasia, Focal                   |                            2                                             |      7  2.0|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +     +  +  +  +  +  +  +  +                                             |  50        |
      Atypia Nuclear                       |                                                                          |      1  2.0|
      Hyperplasia, Focal                   |                      2     2                                             |      7  1.7|
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +     +  I  +  +  +  +  +  +                                             |  49        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  31                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
      Hyperplasia, Focal                   |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | M     M  +  +  +  +  +  +  +                                             |  42        |
      Hyperplasia, Focal                   |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +     +  +  +  +  +  +  +  +                                             |  50        |
      Angiectasis, Focal                   |                                                                          |      1  3.0|
      Pars Distalis, Cyst                  |                                                                          |      3     |
      Pars Distalis, Hyperplasia, Focal    |                         2                                                |      5  2.0|
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |             3                                                            |      1  3.0|
      Pars Distalis, Infiltration Cellular,|                                                                          |            |
           Focal, Histiocyte               |                                                                          |      1  2.0|
      Pars Intermedia, Cyst                |                                                                          |      2     |
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | M     +  +  +  +  +  +  +  +                                             |  49        |
      C-Cell, Hyperplasia, Focal           |                                                                          |      3  1.7|
      C-Cell, Hyperplasia, Multifocal      |                                                                          |      2  1.0|
      Follicular Cell, Hyperplasia, Cystic,|                                                                          |            |
           Focal                           |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +     +  +  +  +  +  +  +  +                                             |  50        |
      Granuloma Sperm, Focal               |                         1                                                |      1  1.0|
      Necrosis                             |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +     +  +  +  +  +  M  +  +                                             |  49        |
      Dilatation                           |                                                                          |      1  4.0|
      Inflammation, Chronic, Focal         | 1                       1                                                |      6  1.7|
      Inflammation, Chronic, Multifocal    |          2  2  2  2        2                                             |     29  2.3|
                                            __________________________________________________________________________|____________|
   Prostate                                | +     +  +  +  +  +  +  +  +                                             |  50        |
      Hyperplasia, Focal                   |                            1                                             |      9  1.6|
      Hyperplasia, Multifocal              |                                                                          |      1  2.0|
      Inflammation, Acute, Focal           |                                                                          |      1  2.0|
      Inflammation, Chronic, Focal         |                         1                                                |      7  2.3|
                                            __________________________________________________________________________|____________|
   Seminal Vesicle                         |                                                                          |   1        |
      Depletion Secretory                  |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Testes                                  | +     +  +  +  +  +  +  +  +                                             |  50        |
      Interstitial Cell, Hyperplasia,      |                                                                          |            |
          Multifocal                       |       3     3     2  2  2                                                |     17  2.1|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  32                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 GENITAL SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Seminiferous Tubule, Degeneration    |             4     4  4                                                   |     12  3.5|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +     +  +  +  +  +  +  +  +                                             |  50        |
      Myelofibrosis, Focal                 |                                                                          |      1  2.0|
      Erythroid Cell, Proliferation        |       4                 4                                                |      7  3.4|
      Myeloid Cell, Proliferation          |             4                                                            |      2  4.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +     +  +  +  +  +  +  +  +                                             |  50        |
      Inguinal, Hyperplasia, Plasma Cell   |       3     4                                                            |      2  3.5|
      Popliteal, Hyperplasia, Lymphoid     |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +     +  +  +  +  +  +  +  +                                             |  50        |
      Cyst, Multiple                       |                                                                          |      1     |
      Erythrophagocytosis                  |                                                                          |      1  2.0|
      Hyperplasia, Lymphoid                |                                                                          |      1  4.0|
      Sinus, Ectasia                       |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +     +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           |                                                                          |      1  4.0|
      Fibrosis, Diffuse                    |                                                                          |      1  4.0|
      Fibrosis, Focal                      |                                                                          |      3  2.7|
      Fibrosis, Multifocal                 |                                                                          |      1  3.0|
      Hematocyst                           |                                                                          |      1     |
      Hematopoietic Cell Proliferation     |       4                 3                                                |      4  3.5|
      Metaplasia, Focal, Osseous           |                                                                          |      1  2.0|
      Pigmentation, Diffuse, Hemosiderin   |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +     +  +  +  +  +  M  +  +                                             |  46        |
      Cyst                                 |                                                                          |      1     |
      Hemorrhage                           | 2                                                                        |      4  2.5|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | +     +  +  +  +  +  +  +  +                                             |  50        |
      Galactocele                          |                                                                          |      3     |
                                            __________________________________________________________________________|____________|
   Skin                                    | +     +  +  +  +  +  +  +  +                                             |  50        |
      Subcutaneous Tissue, Edema           |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +     +  +  +  +  +  +  +  +                                             |  50        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +     +  +  +  +  +  +  +  +                                             |  50        |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  33                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 NERVOUS SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +     +  +  +  +  +  +  +  +                                             |  50        |
      Congestion                           | 3                    2                                                   |      6  2.5|
      Emphysema                            |                                                                          |      1  3.0|
      Hemorrhage, Focal                    |                                                                          |      2  1.5|
      Alveolar Epithelium, Hyperplasia,    |                                                                          |            |
           Focal                           |                3                                                         |      1  3.0|
      Alveolus, Infiltration Cellular,     |                                                                          |            |
           Multifocal, Histiocyte          |                      1                                                   |      1  1.0|
      Alveolus, Inflammation, Chronic,     |                                                                          |            |
           Focal                           |                      2                                                   |      2  2.0|
      Alveolus, Inflammation, Chronic,     |                                                                          |            |
           Multifocal                      |                                                                          |      1  2.0|
      Interstitium, Inflammation, Chronic, |                                                                          |            |
           Diffuse                         |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Nose                                    | +     +  +  +  +  +  +  +  +                                             |  49        |
      Foreign Body                         | 2                                                                        |      2  2.0|
      Inflammation, Chronic                |                                                                          |      1  3.0|
      Inflammation, Suppurative            | 3                                                                        |      2  3.0|
      Metaplasia, Squamous                 | 2                                                                        |      1  2.0|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Chronic                         |                                                                          |      3  3.3|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Suppurative                     |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +     +  +  +  +  +  +  +  +                                             |  50        |
      Glands, Ectasia, Focal               |                                                                          |      1  2.0|
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Eye                                     |                                                                          |   4        |
      Anterior Chamber, Hemorrhage         |                                                                          |      1  3.0|
      Anterior Chamber, Iris, Posterior    |                                                                          |            |
          Chamber, Inflammation            |                                                                          |      1  2.0|
      Cornea, Inflammation                 |                                                                          |      1  3.0|
      Lens, Cataract                       |                                                                          |      3  3.0|
      Retina, Degeneration                 |                                                                          |      2  4.0|
                                            __________________________________________________________________________|____________|
   Lacrimal Gland                          |                         +                                                |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  34                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 2| 4| 4| 7| 7| 7| 7| 6| 4| 7|                                            |            |
                             DAY ON TEST   | 7| 5| 9| 3| 2| 2| 3| 3| 9| 3|                                            |            |
                                           | 9| 6| 2| 0| 9| 9| 0| 7| 2| 0|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 3| 3| 3| 3| 3| 3| 3| 3| 3| 3|                                            |      A     |
    112MG/KG                               | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +     +  +  +  +  +  +  +  +                                             |  50        |
      Cyst                                 |                                                                          |      4     |
      Hyperplasia, Multifocal, Tubular     |                                                                          |      1  2.0|
      Nephropathy, Chronic                 |       2  2  4  3  2  3  2  3                                             |     49  3.0|
      Pigmentation, Diffuse                |                      4                                                   |      2  3.5|
      Cortex, Necrosis, Diffuse            |                                                                          |      1  4.0|
      Pelvis, Parasite Metazoan            |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +     +  +  +  +  +  +  +  +                                             |  50        |
      Concretion                           |                         2                                                |      1  2.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  35                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 3| 3| 4| 7| 1| 3| 3| 4| 7| 4| 4| 7| 5| 7| 1| 4| 4| 5| 7| 2| 4| 5| 5| 7|             
                             DAY ON TEST   | 4| 1| 1| 3| 3| 1| 0| 0| 0| 2| 1| 3| 2| 8| 2| 8| 2| 4| 2| 2| 1| 5| 7| 9| 3|             
                                           | 4| 7| 7| 4| 0| 9| 3| 3| 0| 8| 2| 6| 9| 6| 9| 2| 9| 0| 7| 9| 7| 6| 4| 4| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Inflammation, Chronic, Granulomatous |                                                                          |             
      Perforation                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | +  +  +     +  A  +  +  +  +  +     +  +  +  A  +     +  +  A     +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +     +  A  +  +  +  +  +     +  +  +  A  +     +  +  +     +  +  +|             
      Parasite Metazoan                    |                                                 X                        |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +     I  A  +  +  +  +  +     +  +  +  A  +     +  +  +     +  +  +|             
      Parasite Metazoan                    |                                                          X               |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | +  +  +     +  A  +  +  +  +  +     +  +  +  A  +     +  +  A     +  +  +|             
      Ectopic Tissue                       |                                                                          |             
      Inflammation, Chronic Active, Diffuse|                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | +  +  +     +  A  +  +  +  +  +     +  +  +  A  +     A  +  A     +  +  +|             
      Inflammation, Chronic Active, Diffuse|                                                                          |             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | +  +  +     +  A  +  +  +  +  +     +  +  +  A  +     +  +  A     +  +  +|             
      Inflammation, Chronic Active, Diffuse|                                                                          |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Angiectasis, Focal                   |                                                                          |             
      Basophilic Focus                     |       X                                   X                              |             
      Basophilic Focus, Multiple           |                                     X                                   X|             
      Clear Cell Focus, Multiple           |                                     X                                   X|             
      Congestion                           |                                              3                           |             
      Cytoplasmic Alteration, Focal        |                                                                         2|             
      Eosinophilic Focus                   |                                     2                                    |             
      Hepatodiaphragmatic Nodule           |                                     X                                    |             
      Inflammation, Chronic, Multifocal    |                                        1  2                       1      |             
      Inflammation, Multifocal, Subacute   |                   2                                                      |             
      Necrosis, Focal                      |       1                                                                  |             
      Necrosis, Multifocal                 |                                                                          |             
      Bile Duct, Hyperplasia               |    2  3     2     2  1  2  3  1     3     3     1     3  4  1     2  2  3|             
      Centrilobular, Fatty Change          |                2                                                         |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Atrophy, Focal                       |                            2  3                             2     2     1|             
      Atrophy, Multifocal                  |       3     3                                   3     2  3               |             
      Inflammation, Chronic, Diffuse       |                                                                          |             
      Artery, Inflammation, Chronic        |             3                                                           2|             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Hyperplasia, Focal                   |                                                                          |             
      Infiltration Cellular, Focal,        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  36                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 3| 3| 4| 7| 1| 3| 3| 4| 7| 4| 4| 7| 5| 7| 1| 4| 4| 5| 7| 2| 4| 5| 5| 7|             
                             DAY ON TEST   | 4| 1| 1| 3| 3| 1| 0| 0| 0| 2| 1| 3| 2| 8| 2| 8| 2| 4| 2| 2| 1| 5| 7| 9| 3|             
                                           | 4| 7| 7| 4| 0| 9| 3| 3| 0| 8| 2| 6| 9| 6| 9| 2| 9| 0| 7| 9| 7| 6| 4| 4| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
          Mononuclear Cell                 |                                                 1                        |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Cyst Epithelial Inclusion            |                                                                          |             
      Hyperplasia, Focal, Squamous         |             2                                                            |             
      Inflammation, Acute                  |                                                                      4   |             
      Inflammation, Chronic                |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  A     +  +  +|             
      Erosion, Focal                       |                                                                          |             
      Inflammation, Chronic                |             2                                                            |             
      Mineralization, Diffuse              |             3                                                            |             
                                            __________________________________________________________________________|             
   Tongue                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |             +                                                            |             
      Aorta, Mineralization                |             3                                                            |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Inflammation, Chronic, Focal         |                1        2                                         2      |             
      Inflammation, Chronic, Multifocal    |             3              2        2     3                              |             
      Atrium, Thrombosis                   |             X                                                            |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Cytoplasmic Alteration, Focal        |                                                                         1|             
      Degeneration, Fatty, Focal           |                                           2              3           2   |             
      Degeneration, Fatty, Multifocal      |                                        2                                 |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                          |             
      Hyperplasia, Focal                   |             2                                                            |             
      Hyperplasia, Multifocal              |                            3        3                                   2|             
      Hypertrophy, Focal                   |                                                          3               |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Hyperplasia, Focal                   |             2                                                            |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Hyperplasia, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | M  +  +     +  +  +  +  +  +  +     +  +  M  +  M     +  +  +     +  M  +|             
      Hyperplasia, Diffuse                 |             4                                                            |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Pars Distalis, Hyperplasia, Focal    |                                                                          |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |             3                                                            |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | M  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Congestion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  37                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 3| 3| 4| 7| 1| 3| 3| 4| 7| 4| 4| 7| 5| 7| 1| 4| 4| 5| 7| 2| 4| 5| 5| 7|             
                             DAY ON TEST   | 4| 1| 1| 3| 3| 1| 0| 0| 0| 2| 1| 3| 2| 8| 2| 8| 2| 4| 2| 2| 1| 5| 7| 9| 3|             
                                           | 4| 7| 7| 4| 0| 9| 3| 3| 0| 8| 2| 6| 9| 6| 9| 2| 9| 0| 7| 9| 7| 6| 4| 4| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      C-Cell, Hyperplasia, Focal           |                                                                          |             
      C-Cell, Hyperplasia, Multifocal      |                                                                          |             
      Follicular Cell, Depletion Secretory |                                                             3            |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Inflammation, Acute                  |                                                                          |             
                                            __________________________________________________________________________|             
   Preputial Gland                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Abscess                              |                                                                      4   |             
      Dilatation                           |                                                                          |             
      Hyperplasia                          |                                                                      2   |             
      Inflammation, Chronic, Focal         | 3                    1  2                                                |             
      Inflammation, Chronic, Multifocal    |    2  1                    1  1           2     2        2        3     2|             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +     +  +  +  +  +  +  +     +  +     +  +     +  +  +     +  +  +|             
      Hyperplasia, Focal                   |                                                                          |             
      Hyperplasia, Multifocal              |                                                                          |             
      Inflammation, Chronic, Focal         |    2                                                                     |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |       1     2        1  2     2        2  2     2                 2      |             
      Seminiferous Tubule, Degeneration    |             4                             3              4           2   |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Myelofibrosis, Focal                 |                                                                      2   |             
      Erythroid Cell, Proliferation        |                                        3                 3               |             
      Myeloid Cell, Proliferation          |                                        3                                 |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Congestion                           |                                                                          |             
      Ectasia                              |                                           4                              |             
      Axillary, Hyperplasia, Lymphoid      |                                        2                                 |             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Plasma Cell                     |                                        4                                 |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +     +  +  +  +  +  +  +     +  +  +     +     +  +  +     +  +  +|             
      Hyperplasia, Lymphoid                |                                                             3            |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +     +  M  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Fibrosis, Focal                      |                                           3                              |             
      Hematopoietic Cell Proliferation     |             3                          2                                 |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Hemorrhage                           |                   3  2              1        4  1           3            |             
      Hemorrhage, Multifocal               |                3                                                         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  38                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 3| 3| 4| 7| 1| 3| 3| 4| 7| 4| 4| 7| 5| 7| 1| 4| 4| 5| 7| 2| 4| 5| 5| 7|             
                             DAY ON TEST   | 4| 1| 1| 3| 3| 1| 0| 0| 0| 2| 1| 3| 2| 8| 2| 8| 2| 4| 2| 2| 1| 5| 7| 9| 3|             
                                           | 4| 7| 7| 4| 0| 9| 3| 3| 0| 8| 2| 6| 9| 6| 9| 2| 9| 0| 7| 9| 7| 6| 4| 4| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Subcutaneous Tissue, Abscess         |                                        4                                 |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Fibrous Osteodystrophy               |             X                             X                              |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Mineralization, Multifocal           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Congestion                           | 3              3  3     3                    3                           |             
      Edema, Focal                         |                                                                          |             
      Emphysema                            |                                                                          |             
      Foreign Body                         |                                                                          |             
      Hemorrhage, Focal                    | 2                       2                                                |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |             3                                                            |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                                                                          |             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Histiocyte                      |                                                                          |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Multifocal, Suppurative|                                                                          |             
      Necrosis, Acute                      |                                                                          |             
      Pigmentation, Multifocal             |                                                                          |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Focal                           |                                                                          |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Focal                           |                                                                          |             
      Perivascular, Edema, Multifocal      |                               3                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Congestion                           |                                                                          |             
      Foreign Body                         |                                     1     1                       1      |             
      Fungus                               |                                                                         X|             
      Inflammation, Chronic                |                                     1     2                             2|             
      Inflammation, Suppurative            |                   1        1                                             |             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  39                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 0| 3| 3| 4| 7| 1| 3| 3| 4| 7| 4| 4| 7| 5| 7| 1| 4| 4| 5| 7| 2| 4| 5| 5| 7|             
                             DAY ON TEST   | 4| 1| 1| 3| 3| 1| 0| 0| 0| 2| 1| 3| 2| 8| 2| 8| 2| 4| 2| 2| 1| 5| 7| 9| 3|             
                                           | 4| 7| 7| 4| 0| 9| 3| 3| 0| 8| 2| 6| 9| 6| 9| 2| 9| 0| 7| 9| 7| 6| 4| 4| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0| 1| 1| 1| 1| 1| 2| 2| 2| 2| 2| 3| 3| 3| 3| 3|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
           Suppurative                     |                                                                          |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Inflammation, Chronic                |                                                                          |             
      Inflammation, Suppurative            |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                                          |             
                                            __________________________________________________________________________|             
   Eye                                     |       +                                      A                           |             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                                                                      +   |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +     +  +  +     +  +  +|             
      Congestion                           |                                                                          |             
      Cyst                                 |             X                                                            |             
      Hydronephrosis, Chronic              |                                                                          |             
      Hyperplasia, Multifocal, Tubular     |                            1              1              1               |             
      Nephropathy, Chronic                 |    1  2     4     2  1  2  4  2     3  3  4  1  2     2  4        2  3  2|             
      Pigmentation, Diffuse                |                                                                          |             
      Pigmentation                         |                                                                          |             
      Cortex, Mineralization, Multifocal   |             3                                                            |             
      Papilla, Transitional Epithelium,    |                                                                          |             
           Hyperplasia                     |                                                          2               |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +     +  +  +  +  +  +  +     +  +  +  +  +        +  +     +  +  +|             
      Concretion                           |    3           2                                                         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  40                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 2| 2| 5| 7| 7| 3| 3| 6| 7| 6| 4| 4| 4| 4| 5| 0| 4| 4| 5| 5| 2| 5| 7| 3| 3|             
                             DAY ON TEST   | 5| 6| 7| 2| 3| 0| 9| 1| 3| 2| 2| 5| 5| 5| 6| 1| 5| 9| 0| 7| 8| 3| 0| 3| 3|             
                                           | 5| 2| 6| 9| 0| 7| 9| 1| 0| 5| 9| 6| 6| 6| 0| 0| 4| 2| 3| 4| 2| 7| 6| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM                         |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Esophagus                               | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Granulomatous |                                                                          |             
      Perforation                          |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large                         | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Large, Cecum                  | A  A  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |                                                                          |             
                                            __________________________________________________________________________|             
   Intestine Large, Colon                  | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |          X           X  X                                                |             
                                            __________________________________________________________________________|             
   Intestine Large, Rectum                 | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Parasite Metazoan                    |             X  X                                                         |             
                                            __________________________________________________________________________|             
   Intestine Small                         | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Intestine Small, Duodenum               | A  A  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Ectopic Tissue                       |                                                             X            |             
      Inflammation, Chronic Active, Diffuse|                                                             3            |             
                                            __________________________________________________________________________|             
   Intestine Small, Ileum                  | A  A  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Chronic Active, Diffuse|                                                             3            |             
      Parasite Metazoan                    |                                                                X         |             
                                            __________________________________________________________________________|             
   Intestine Small, Jejunum                | A  A  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Chronic Active, Diffuse|                                                             3            |             
                                            __________________________________________________________________________|             
   Liver                                   | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Angiectasis, Focal                   |             2                                                            |             
      Basophilic Focus                     |                                                                          |             
      Basophilic Focus, Multiple           |          X              X                                         X      |             
      Clear Cell Focus, Multiple           |                         X                                                |             
      Congestion                           |                                                                          |             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Eosinophilic Focus                   |                                                                          |             
      Hepatodiaphragmatic Nodule           |                                                                   X     X|             
      Inflammation, Chronic, Multifocal    |          2           1                                                   |             
      Inflammation, Multifocal, Subacute   |                                                                          |             
      Necrosis, Focal                      |                                                                          |             
      Necrosis, Multifocal                 |                            2              2                          2   |             
      Bile Duct, Hyperplasia               | 2     3  3  3  1  3  2  3  2  2           2        2  2  2  2  4  3  2   |             
      Centrilobular, Fatty Change          |                                                                          |             
                                            __________________________________________________________________________|             
   Mesentery                               |                                                                          |             
      Fat, Necrosis                        |                                                                          |             
                                            __________________________________________________________________________|             
   Pancreas                                | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Atrophy, Focal                       |                      2  4                          1     2               |             
      Atrophy, Multifocal                  |       2        2                                               3         |             
      Inflammation, Chronic, Diffuse       |                                           3                              |             
      Artery, Inflammation, Chronic        |                                                                          |             
                                            __________________________________________________________________________|             
   Salivary Glands                         | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                         1                                                |             
      Infiltration Cellular, Focal,        |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  41                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 2| 2| 5| 7| 7| 3| 3| 6| 7| 6| 4| 4| 4| 4| 5| 0| 4| 4| 5| 5| 2| 5| 7| 3| 3|             
                             DAY ON TEST   | 5| 6| 7| 2| 3| 0| 9| 1| 3| 2| 2| 5| 5| 5| 6| 1| 5| 9| 0| 7| 8| 3| 0| 3| 3|             
                                           | 5| 2| 6| 9| 0| 7| 9| 1| 0| 5| 9| 6| 6| 6| 0| 0| 4| 2| 3| 4| 2| 7| 6| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ALIMENTARY SYSTEM - cont                  |                                                                          |             
                                           |                                                                          |             
          Mononuclear Cell                 |                                                                          |             
                                            __________________________________________________________________________|             
   Stomach                                 | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Stomach, Forestomach                    | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Cyst Epithelial Inclusion            |                         X                                                |             
      Hyperplasia, Focal, Squamous         |             3                                                            |             
      Inflammation, Acute                  |                                                                          |             
      Inflammation, Chronic                |             3                                                            |             
                                            __________________________________________________________________________|             
   Stomach, Glandular                      | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Erosion, Focal                       |                            2              1                              |             
      Inflammation, Chronic                |                                                                          |             
      Mineralization, Diffuse              |                                                                          |             
                                            __________________________________________________________________________|             
   Tongue                                  |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 CARDIOVASCULAR SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Blood Vessel                            |                                                                          |             
      Aorta, Mineralization                |                                                                          |             
                                            __________________________________________________________________________|             
   Heart                                   | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Chronic, Focal         |                                                    2                     |             
      Inflammation, Chronic, Multifocal    |                      2                                3  2        3      |             
      Atrium, Thrombosis                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM                          |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland                           | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Adrenal Gland, Cortex                   | M  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Cytoplasmic Alteration, Focal        |                                                                          |             
      Degeneration, Fatty, Focal           |                                                                   1      |             
      Degeneration, Fatty, Multifocal      |          2                                                               |             
      Hematopoietic Cell Proliferation,    |                                                                          |             
           Multifocal                      |                                                                   2      |             
      Hyperplasia, Focal                   |                                                                          |             
      Hyperplasia, Multifocal              |                                                                          |             
      Hypertrophy, Focal                   |                                                                          |             
                                            __________________________________________________________________________|             
   Adrenal Gland, Medulla                  | M  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |          2  2                                                     2      |             
                                            __________________________________________________________________________|             
   Islets, Pancreatic                      | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                            2                                             |             
                                            __________________________________________________________________________|             
   Parathyroid Gland                       | +  +  +  +  +  +  +  +  +  +  +           +  M     +  +  +  +  +  +  +  +|             
      Hyperplasia, Diffuse                 |                                                                          |             
                                            __________________________________________________________________________|             
   Pituitary Gland                         | M  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Pars Distalis, Hyperplasia, Focal    |             2                                      1                     |             
      Pars Distalis, Hyperplasia,          |                                                                          |             
          Multifocal                       |                            3                                             |             
                                            __________________________________________________________________________|             
   Thyroid Gland                           | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Congestion                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  42                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 2| 2| 5| 7| 7| 3| 3| 6| 7| 6| 4| 4| 4| 4| 5| 0| 4| 4| 5| 5| 2| 5| 7| 3| 3|             
                             DAY ON TEST   | 5| 6| 7| 2| 3| 0| 9| 1| 3| 2| 2| 5| 5| 5| 6| 1| 5| 9| 0| 7| 8| 3| 0| 3| 3|             
                                           | 5| 2| 6| 9| 0| 7| 9| 1| 0| 5| 9| 6| 6| 6| 0| 0| 4| 2| 3| 4| 2| 7| 6| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 ENDOCRINE SYSTEM - cont                   |                                                                          |             
                                           |                                                                          |             
      C-Cell, Hyperplasia, Focal           |                                                                          |             
      C-Cell, Hyperplasia, Multifocal      |                                                          2               |             
      Follicular Cell, Depletion Secretory |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENERAL BODY SYSTEM                       |                                                                          |             
                                           |                                                                          |             
    None                                   |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 GENITAL SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Epididymis                              | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Acute                  |                                                          2               |             
                                            __________________________________________________________________________|             
   Preputial Gland                         | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Abscess                              |                                                                          |             
      Dilatation                           |                                                                   4      |             
      Hyperplasia                          |                                                                          |             
      Inflammation, Chronic, Focal         |       1                       2                          2     1         |             
      Inflammation, Chronic, Multifocal    |          3  2  3     2  2  2                                2            |             
                                            __________________________________________________________________________|             
   Prostate                                | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hyperplasia, Focal                   |                                                                   1      |             
      Hyperplasia, Multifocal              |                                                                          |             
      Inflammation, Chronic, Focal         |    2     1     1                                      2  2               |             
                                            __________________________________________________________________________|             
   Testes                                  | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Interstitial Cell, Hyperplasia,      |                                                                          |             
          Multifocal                       |             2     2     3     2           2        3     2  2  2  3  2  1|             
      Seminiferous Tubule, Degeneration    |             4           4  4                                      4      |             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone Marrow                             | +  +  +  +  +  +  +  +  +  +  +           +  M     +  +  +  +  +  +  +  +|             
      Myelofibrosis, Focal                 |                                                                          |             
      Erythroid Cell, Proliferation        |                                                                   3      |             
      Myeloid Cell, Proliferation          |                                                                3         |             
                                            __________________________________________________________________________|             
   Lymph Node                              | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Congestion                           |                                                                          |             
      Ectasia                              |                                                                          |             
      Axillary, Hyperplasia, Lymphoid      |                                                                          |             
      Axillary, Infiltration Cellular,     |                                                                          |             
           Plasma Cell                     |                                                                          |             
                                            __________________________________________________________________________|             
   Lymph Node, Mesenteric                  | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hyperplasia, Lymphoid                |                                                                          |             
                                            __________________________________________________________________________|             
   Spleen                                  | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Fibrosis, Focal                      |                                                                          |             
      Hematopoietic Cell Proliferation     |          2              2                                         4      |             
                                            __________________________________________________________________________|             
   Thymus                                  | +  +  +  M  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Hemorrhage                           | 3  4                          3                       3     3           3|             
      Hemorrhage, Multifocal               |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  43                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 2| 2| 5| 7| 7| 3| 3| 6| 7| 6| 4| 4| 4| 4| 5| 0| 4| 4| 5| 5| 2| 5| 7| 3| 3|             
                             DAY ON TEST   | 5| 6| 7| 2| 3| 0| 9| 1| 3| 2| 2| 5| 5| 5| 6| 1| 5| 9| 0| 7| 8| 3| 0| 3| 3|             
                                           | 5| 2| 6| 9| 0| 7| 9| 1| 0| 5| 9| 6| 6| 6| 0| 0| 4| 2| 3| 4| 2| 7| 6| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |             
                                           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 INTEGUMENTARY SYSTEM                      |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Mammary Gland                           | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
                                            __________________________________________________________________________|             
   Skin                                    | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Subcutaneous Tissue, Abscess         |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 MUSCULOSKELETAL SYSTEM                    |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Bone                                    | +  +  +  +  +  +  +  +  +  +  +           +  M     +  +  +  +  +  +  +  +|             
      Fibrous Osteodystrophy               |                                                                          |             
                                            __________________________________________________________________________|             
   Skeletal Muscle                         |                                                                   +      |             
 _____________________________________________________________________________________________________________________|             
 NERVOUS SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Brain                                   | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Mineralization, Multifocal           |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM                        |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Lung                                    | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Congestion                           |                                                             4            |             
      Edema, Focal                         |                                                                         2|             
      Emphysema                            |                                                             4            |             
      Foreign Body                         |                                              1                           |             
      Hemorrhage, Focal                    |                                                                          |             
      Infiltration Cellular, Diffuse,      |                                                                          |             
          Histiocyte                       |                                                                          |             
      Infiltration Cellular, Mononuclear   |                                                                          |             
          Cell, Multifocal                 |                   2                                                      |             
      Infiltration Cellular, Multifocal,   |                                                                          |             
           Histiocyte                      |                   1                                                      |             
      Inflammation, Acute                  |                                                             3            |             
      Inflammation, Multifocal, Suppurative|                                              3                           |             
      Necrosis, Acute                      |                                                             4            |             
      Pigmentation, Multifocal             |                         2                                                |             
      Alveolus, Inflammation, Chronic,     |                                                                          |             
           Focal                           |                      1                                                   |             
      Interstitium, Inflammation, Chronic, |                                                                          |             
           Focal                           |                         2                                                |             
      Perivascular, Edema, Multifocal      |                                                                          |             
                                            __________________________________________________________________________|             
   Nose                                    | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Congestion                           |                               4                             3            |             
      Foreign Body                         |    1                                                                     |             
      Fungus                               |                                                       X                  |             
      Inflammation, Chronic                |                                                       3        2         |             
      Inflammation, Suppurative            | 2  2                                                        2     2     2|             
      Nasolacrimal Duct, Inflammation,     |                                                                          |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  44                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 _____________________________________________________________________________________________________________________              
                                           | 2| 2| 5| 7| 7| 3| 3| 6| 7| 6| 4| 4| 4| 4| 5| 0| 4| 4| 5| 5| 2| 5| 7| 3| 3|             
                             DAY ON TEST   | 5| 6| 7| 2| 3| 0| 9| 1| 3| 2| 2| 5| 5| 5| 6| 1| 5| 9| 0| 7| 8| 3| 0| 3| 3|             
                                           | 5| 2| 6| 9| 0| 7| 9| 1| 0| 5| 9| 6| 6| 6| 0| 0| 4| 2| 3| 4| 2| 7| 6| 9| 0|             
 _____________________________________________________________________________________________________________________|             
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|             
                               ANIMAL ID   | 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5| 5|             
    225MG/KG                               | 4| 4| 4| 4| 4| 5| 5| 5| 5| 5| 6| 6| 6| 6| 6| 7| 7| 7| 7| 7| 8| 8| 8| 8| 8|             
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|             
 _____________________________________________________________________________________________________________________|             
 RESPIRATORY SYSTEM - cont                 |                                                                          |             
                                           |                                                                          |             
           Suppurative                     |    2                 2                                                   |             
                                            __________________________________________________________________________|             
   Trachea                                 | +  +  +  +     +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Inflammation, Chronic                |                                                          3               |             
      Inflammation, Suppurative            |                                              4                           |             
 _____________________________________________________________________________________________________________________|             
 SPECIAL SENSES SYSTEM                     |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Ear                                     |                                                    +                     |             
                                            __________________________________________________________________________|             
   Eye                                     |                                           +        +           +        +|             
                                            __________________________________________________________________________|             
   Zymbal's Gland                          |                                                                          |             
 _____________________________________________________________________________________________________________________|             
 URINARY SYSTEM                            |                                                                          |             
                                           |                                                                          |             
                                            __________________________________________________________________________|             
   Kidney                                  | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Congestion                           |                3                                                         |             
      Cyst                                 |          X  X                                                            |             
      Hydronephrosis, Chronic              |                                                       2                  |             
      Hyperplasia, Multifocal, Tubular     |          1  1                                                            |             
      Nephropathy, Chronic                 | 1     2  3  3  1  2  3  2  3  2           3        2     2  2  4  2  1  1|             
      Pigmentation, Diffuse                |                                                                4         |             
      Pigmentation                         |                                                                   4      |             
      Cortex, Mineralization, Multifocal   |                                                                          |             
      Papilla, Transitional Epithelium,    |                                                                          |             
           Hyperplasia                     |                                                                          |             
                                            __________________________________________________________________________|             
   Urinary Bladder                         | +  +  +  +  +  +  +  +  +  +  +           +  +     +  +  +  +  +  +  +  +|             
      Concretion                           |                2                                                         |             
 _____________________________________________________________________________________________________________________|             
                                                             Page  45                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM                         |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Esophagus                               | +  +  +  +  +        +  +  +                                             |  50        |
      Inflammation, Chronic, Granulomatous |                      4                                                   |      1  4.0|
      Perforation                          |                      X                                                   |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large                         | +  +  +  +  +        +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Large, Cecum                  | +  A  +  +  +        +  +  +                                             |  44        |
      Parasite Metazoan                    |       X                                                                  |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Colon                  | +  A     +  +        +  +  +                                             |  46        |
      Parasite Metazoan                    |             X              X                                             |      6     |
                                            __________________________________________________________________________|____________|
   Intestine Large, Rectum                 | +  +  +  +  +        +  +  +                                             |  47        |
      Parasite Metazoan                    |             X              X                                             |      5     |
                                            __________________________________________________________________________|____________|
   Intestine Small                         | +  +  +  +  +        +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Intestine Small, Duodenum               | +  A  +  +  +        +  +  +                                             |  44        |
      Ectopic Tissue                       |                                                                          |      1     |
      Inflammation, Chronic Active, Diffuse|                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Intestine Small, Ileum                  | +  A  +  +  +        +  +  +                                             |  43        |
      Inflammation, Chronic Active, Diffuse|                                                                          |      1  3.0|
      Parasite Metazoan                    |                                                                          |      1     |
                                            __________________________________________________________________________|____________|
   Intestine Small, Jejunum                | +  A  +  +  +        +  +  +                                             |  44        |
      Inflammation, Chronic Active, Diffuse|                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Liver                                   | +  +  +  +  +        +  +  +                                             |  50        |
      Angiectasis, Focal                   |                                                                          |      1  2.0|
      Basophilic Focus                     |                            X                                             |      3     |
      Basophilic Focus, Multiple           |          X                                                               |      6     |
      Clear Cell Focus, Multiple           |                                                                          |      3     |
      Congestion                           |                            3                                             |      2  3.0|
      Cytoplasmic Alteration, Focal        |                                                                          |      1  2.0|
      Eosinophilic Focus                   |                                                                          |      1  2.0|
      Hepatodiaphragmatic Nodule           |                                                                          |      3     |
      Inflammation, Chronic, Multifocal    |                                                                          |      5  1.4|
      Inflammation, Multifocal, Subacute   |                                                                          |      1  2.0|
      Necrosis, Focal                      |    1                                                                     |      2  1.0|
      Necrosis, Multifocal                 |                                                                          |      3  2.0|
      Bile Duct, Hyperplasia               |    1  1  1  3        2  4  1                                             |     42  2.2|
      Centrilobular, Fatty Change          |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Mesentery                               |                            +                                             |   1        |
      Fat, Necrosis                        |                            4                                             |      1  4.0|
                                            __________________________________________________________________________|____________|
   Pancreas                                | +  +  +  +  +        +  +  +                                             |  50        |
      Atrophy, Focal                       |                                                                          |      9  2.1|
      Atrophy, Multifocal                  |                         2                                                |      9  2.6|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  46                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ALIMENTARY SYSTEM - cont                  |                                                                          |            |
                                           |                                                                          |            |
      Inflammation, Chronic, Diffuse       |                                                                          |      1  3.0|
      Artery, Inflammation, Chronic        |                                                                          |      2  2.5|
                                            __________________________________________________________________________|____________|
   Salivary Glands                         | +  +  +  +  +        +  +  +                                             |  50        |
      Hyperplasia, Focal                   |                                                                          |      1  1.0|
      Infiltration Cellular, Focal,        |                                                                          |            |
          Mononuclear Cell                 |                                                                          |      1  1.0|
                                            __________________________________________________________________________|____________|
   Stomach                                 | +  +  +  +  +        +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Stomach, Forestomach                    | +  +  +  +  +        +  +  +                                             |  50        |
      Cyst Epithelial Inclusion            |                                                                          |      1     |
      Hyperplasia, Focal, Squamous         |                                                                          |      2  2.5|
      Inflammation, Acute                  |                                                                          |      1  4.0|
      Inflammation, Chronic                |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Stomach, Glandular                      | +  +  +  +  +        +  +  +                                             |  49        |
      Erosion, Focal                       |                                                                          |      2  1.5|
      Inflammation, Chronic                |                                                                          |      1  2.0|
      Mineralization, Diffuse              |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Tongue                                  |                            +                                             |   1        |
 _____________________________________________________________________________________________________________________|            |
 CARDIOVASCULAR SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Blood Vessel                            |                                                                          |   1        |
      Aorta, Mineralization                |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Heart                                   | +  +  +  +  +        +  +  +                                             |  50        |
      Inflammation, Chronic, Focal         |       2     2                                                            |      6  1.8|
      Inflammation, Chronic, Multifocal    |          2                 3                                             |     10  2.5|
      Atrium, Thrombosis                   |                                                                          |      1     |
 _____________________________________________________________________________________________________________________|            |
 ENDOCRINE SYSTEM                          |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Adrenal Gland                           | +  +  +  +  +        +  +  +                                             |  50        |
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Cortex                   | +  +  +  +  +        +  +  +                                             |  49        |
      Cytoplasmic Alteration, Focal        |                                                                          |      1  1.0|
      Degeneration, Fatty, Focal           |          2                                                               |      5  2.0|
      Degeneration, Fatty, Multifocal      |                                                                          |      2  2.0|
      Hematopoietic Cell Proliferation,    |                                                                          |            |
           Multifocal                      |                                                                          |      1  2.0|
      Hyperplasia, Focal                   |                         3                                                |      2  2.5|
      Hyperplasia, Multifocal              |                                                                          |      3  2.7|
      Hypertrophy, Focal                   |                         2                                                |      2  2.5|
                                            __________________________________________________________________________|____________|
   Adrenal Gland, Medulla                  | +  +  +  +  +        +  +  +                                             |  49        |
      Hyperplasia, Focal                   |                      3     2                                             |      6  2.2|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  47                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 ENDOCRINE SYSTEM - cont                   |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Islets, Pancreatic                      | +  +  +  +  +        +  +  +                                             |  50        |
      Hyperplasia, Focal                   |                         2                                                |      2  2.0|
                                            __________________________________________________________________________|____________|
   Parathyroid Gland                       | +  M  +  +  +        +  +  +                                             |  44        |
      Hyperplasia, Diffuse                 |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Pituitary Gland                         | +  +  +  +  +        +  +  +                                             |  49        |
      Pars Distalis, Hyperplasia, Focal    |          1                                                               |      3  1.3|
      Pars Distalis, Hyperplasia,          |                                                                          |            |
          Multifocal                       |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Thyroid Gland                           | +  +  +  +  +        +  +  +                                             |  49        |
      Congestion                           | 2                                                                        |      1  2.0|
      C-Cell, Hyperplasia, Focal           |       2  2                                                               |      2  2.0|
      C-Cell, Hyperplasia, Multifocal      |                                                                          |      1  2.0|
      Follicular Cell, Depletion Secretory |    3                                                                     |      2  3.0|
 _____________________________________________________________________________________________________________________|            |
 GENERAL BODY SYSTEM                       |                                                                          |            |
                                           |                                                                          |            |
    None                                   |                                                                          |            |
 _____________________________________________________________________________________________________________________|            |
 GENITAL SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Epididymis                              | +  +  +  +  +        +  +  +                                             |  50        |
      Inflammation, Acute                  |                                                                          |      1  2.0|
                                            __________________________________________________________________________|____________|
   Preputial Gland                         | +  +  +  +  +        +  +  +                                             |  50        |
      Abscess                              |                                                                          |      1  4.0|
      Dilatation                           |                                                                          |      1  4.0|
      Hyperplasia                          |                                                                          |      1  2.0|
      Inflammation, Chronic, Focal         |       1                                                                  |      8  1.6|
      Inflammation, Chronic, Multifocal    |             2           3                                                |     18  2.1|
                                            __________________________________________________________________________|____________|
   Prostate                                | +  +  +  +  +        +  +  +                                             |  49        |
      Hyperplasia, Focal                   |                                                                          |      1  1.0|
      Hyperplasia, Multifocal              |                            2                                             |      1  2.0|
      Inflammation, Chronic, Focal         |             2        3                                                   |      8  1.9|
                                            __________________________________________________________________________|____________|
   Testes                                  | +  +  +  +  +        +  +  +                                             |  50        |
      Interstitial Cell, Hyperplasia,      |                                                                          |            |
          Multifocal                       |       3                                                                  |     22  2.0|
      Seminiferous Tubule, Degeneration    |             3                                                            |      9  3.6|
 _____________________________________________________________________________________________________________________|            |
 HEMATOPOIETIC SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone Marrow                             | +  +  +  +  +        +  +  +                                             |  49        |
      Myelofibrosis, Focal                 |                                                                          |      1  2.0|
      Erythroid Cell, Proliferation        |          3                                                               |      4  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  48                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 HEMATOPOIETIC SYSTEM - cont               |                                                                          |            |
                                           |                                                                          |            |
      Myeloid Cell, Proliferation          |                                                                          |      2  3.0|
                                            __________________________________________________________________________|____________|
   Lymph Node                              | +  +  +  +  +        +  +  +                                             |  50        |
      Congestion                           |                            3                                             |      1  3.0|
      Ectasia                              |                                                                          |      1  4.0|
      Axillary, Hyperplasia, Lymphoid      |                                                                          |      1  2.0|
      Axillary, Infiltration Cellular,     |                                                                          |            |
           Plasma Cell                     |                                                                          |      1  4.0|
                                            __________________________________________________________________________|____________|
   Lymph Node, Mesenteric                  | +  +  +  +  +        +  +  +                                             |  49        |
      Hyperplasia, Lymphoid                |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Spleen                                  | +  +  +  +  +        +  +  +                                             |  49        |
      Fibrosis, Focal                      |                                                                          |      1  3.0|
      Hematopoietic Cell Proliferation     |             2                                                            |      6  2.5|
                                            __________________________________________________________________________|____________|
   Thymus                                  | +  +  +  +  +        +  +  M                                             |  48        |
      Hemorrhage                           |    4  2                 2                                                |     15  2.7|
      Hemorrhage, Multifocal               | 2                                                                        |      2  2.5|
 _____________________________________________________________________________________________________________________|            |
 INTEGUMENTARY SYSTEM                      |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Mammary Gland                           | I  +  +  +  +        +  +  +                                             |  49        |
                                            __________________________________________________________________________|____________|
   Skin                                    | +  +  +  +  +        +  +  +                                             |  50        |
      Subcutaneous Tissue, Abscess         |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 MUSCULOSKELETAL SYSTEM                    |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Bone                                    | +  +  +  +  +        +  +  +                                             |  49        |
      Fibrous Osteodystrophy               |                                                                          |      2     |
                                            __________________________________________________________________________|____________|
   Skeletal Muscle                         |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 NERVOUS SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Brain                                   | +  +  +  +  +        +  +  +                                             |  50        |
      Mineralization, Multifocal           |                      4                                                   |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 RESPIRATORY SYSTEM                        |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Lung                                    | +  +  +  +  +        +  +  +                                             |  50        |
      Congestion                           | 3  3  3     3              3                                             |     11  3.1|
      Edema, Focal                         |                                                                          |      1  2.0|
      Emphysema                            |                                                                          |      1  4.0|
      Foreign Body                         |                                                                          |      1  1.0|
      Hemorrhage, Focal                    |                                                                          |      2  2.0|
      Infiltration Cellular, Diffuse,      |                                                                          |            |
          Histiocyte                       |                                                                          |      1  3.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  49                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 RESPIRATORY SYSTEM - cont                 |                                                                          |            |
                                           |                                                                          |            |
      Infiltration Cellular, Mononuclear   |                                                                          |            |
          Cell, Multifocal                 |                                                                          |      1  2.0|
      Infiltration Cellular, Multifocal,   |                                                                          |            |
           Histiocyte                      |                                                                          |      1  1.0|
      Inflammation, Acute                  |                                                                          |      1  3.0|
      Inflammation, Multifocal, Suppurative|                                                                          |      1  3.0|
      Necrosis, Acute                      |                                                                          |      1  4.0|
      Pigmentation, Multifocal             |                                                                          |      1  2.0|
      Alveolus, Inflammation, Chronic,     |                                                                          |            |
           Focal                           |                                                                          |      1  1.0|
      Interstitium, Inflammation, Chronic, |                                                                          |            |
           Focal                           |                                                                          |      1  2.0|
      Perivascular, Edema, Multifocal      |                                                                          |      1  3.0|
                                            __________________________________________________________________________|____________|
   Nose                                    | +  +  +  +  +        +  +  +                                             |  50        |
      Congestion                           |                                                                          |      2  3.5|
      Foreign Body                         |                                                                          |      4  1.0|
      Fungus                               |                                                                          |      2     |
      Inflammation, Chronic                |                                                                          |      5  2.0|
      Inflammation, Suppurative            |                                                                          |      7  1.7|
      Nasolacrimal Duct, Inflammation,     |                                                                          |            |
           Suppurative                     |                                                                          |      2  2.0|
                                            __________________________________________________________________________|____________|
   Trachea                                 | +  +  +  +  +        +  +  +                                             |  49        |
      Inflammation, Chronic                |                                                                          |      1  3.0|
      Inflammation, Suppurative            |                                                                          |      1  4.0|
 _____________________________________________________________________________________________________________________|            |
 SPECIAL SENSES SYSTEM                     |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Ear                                     |                                                                          |   1        |
                                            __________________________________________________________________________|____________|
   Eye                                     |                      +                                                   |   6        |
                                            __________________________________________________________________________|____________|
   Zymbal's Gland                          |                                                                          |   1        |
 _____________________________________________________________________________________________________________________|            |
 URINARY SYSTEM                            |                                                                          |            |
                                           |                                                                          |            |
                                            __________________________________________________________________________|____________|
   Kidney                                  | +  +  +  +  +        +  +  +                                             |  50        |
      Congestion                           | 2                                                                        |      2  2.5|
      Cyst                                 |                                                                          |      3     |
      Hydronephrosis, Chronic              |                                                                          |      1  2.0|
      Hyperplasia, Multifocal, Tubular     |                                                                          |      5  1.0|
      Nephropathy, Chronic                 |    1  2  3  4        2  4  4                                             |     43  2.4|
      Pigmentation, Diffuse                |                                                                          |      1  4.0|
      Pigmentation                         |                                                                          |      1  4.0|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  50                                                               
NTP Experiment-Test: 05704-02                  NONNEOPLASTIC LESIONS BY INDIVIDUAL ANIMAL                         Report: PEIRPT09
Study Type: CHRONIC                                             RESORCINOL                                        Date: 04/29/97  
Route: GAVAGE                                                                                                     Time: 08:29:59  
                                                                                                                                    
 __________________________________________________________________________________________________________________________________ 
                                           | 0| 2| 4| 7| 6| 4| 4| 5| 7| 7|                                            |            |
                             DAY ON TEST   | 5| 6| 1| 3| 5| 4| 6| 3| 2| 2|                                            |            |
                                           | 8| 9| 9| 0| 3| 3| 9| 8| 1| 1|                                            |      T (*) |
 _____________________________________________________________________________________________________________________|            |
                                           | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      O     |
   FISCHER 344 RATS MALE                   | 0| 0| 0| 0| 0| 0| 0| 0| 0| 0|                                            |      T     |
                               ANIMAL ID   | 5| 5| 5| 5| 5| 6| 6| 6| 6| 6|                                            |      A     |
    225MG/KG                               | 9| 9| 9| 9| 9| 0| 0| 0| 0| 0|                                            |      L     |
      MALE                                 | 1| 2| 3| 4| 5| 1| 2| 3| 4| 5|                                            |            |
 __________________________________________________________________________________________________________________________________ 
 URINARY SYSTEM - cont                     |                                                                          |            |
                                           |                                                                          |            |
      Cortex, Mineralization, Multifocal   |                                                                          |      1  3.0|
      Papilla, Transitional Epithelium,    |                                                                          |            |
           Hyperplasia                     |          2                                                               |      2  2.0|
                                            __________________________________________________________________________|____________|
   Urinary Bladder                         | +  +  +  +  +        +  +  +                                             |  49        |
      Concretion                           |       3                                                                  |      4  2.5|
 __________________________________________________________________________________________________________________________________ 
  * : Total animals with tissue examined microscopically; total animals with lesion and mean severity grade                         
  + : Tissue examined microscopically                M : Missing tissue                        1-4 : Lesion qualified as:           
  X : Lesion present but not qualified               A : Autolysis precludes examination               1) Minimal  3) Moderate      
  I : Insufficient tissue                        BLANK : Not examined                                  2) Mild     4) Marked        
                                                             Page  51                                                               
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