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TDMS Study 05704-01 Pathology Tables


                              INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)
                                                             RESORCINOL


NTP Experiment-Test: 05704-01                                                                                     Report: PEIRPT05
Study Type: CHRONIC                                                                                               Date: 09/18/94
Route: GAVAGE                                                                                                     Time: 17:01:01




       Facility:  International Research and Development Corp.

       Chemical CAS #:  108-46-3

       Lock Date:  None

       Cage Range:  All

       Reasons For Removal:    All

       Removal Date Range:     All

       Treatment Groups:       Include All
































a  Number of animals examined microscopically at site and number of animals with lesion

                                                             Page   1

NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        CONTROL      112MG/KG     225MG/KG                                               
                                                   F             FEMALE       FEMALE                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
  Animals Initially in Study                          60           60           60                                                  
  Scheduled Sacrifice                                 10           10           10                                                  
  Early Deaths                                                                                                                      
    Dead                                               9            9           11                                                  
    Moribund                                           2            8            5                                                  
    Accident                                           1                                                                            
  Survivors                                                                                                                         
    Terminal Sacrifice                                37           33           34                                                  
    Dead                                               1                                                                            
  Animals Examined Microscopically                    50           50           50                                                  
                                                                                                                                    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Esophagus                                          (50)                      (49)                                                
   Gallbladder                                        (43)                      (39)                                                
   Intestine Large, Cecum                             (48)         (1)          (44)                                                
   Intestine Large, Colon                             (50)         (1)          (48)                                                
   Intestine Large, Rectum                            (49)         (1)          (50)                                                
   Intestine Small, Duodenum                          (47)         (2)          (42)                                                
   Intestine Small, Ileum                             (44)         (1)          (41)                                                
   Intestine Small, Jejunum                           (47)         (2)          (42)                                                
   Liver                                              (50)         (5)          (50)                                                
      Fibrosarcoma, Metastatic, Skin                   1 (2%)                                                                       
      Hemangiosarcoma, Metastatic, Spleen              1 (2%)                                                                       
      Hepatocellular Carcinoma                         1 (2%)       1 (20%)      3 (6%)                                             
      Hepatocellular Adenoma                           1 (2%)                    2 (4%)                                             
   Mesentery                                          (1)          (1)          (2)                                                 
   Pancreas                                           (48)                      (48)                                                
   Salivary Glands                                    (48)                      (47)                                                
   Stomach, Forestomach                               (49)         (3)          (46)                                                
      Squamous Cell Papilloma                                       1 (33%)      1 (2%)                                             
      Squamous Cell Papilloma, Multiple                                          1 (2%)                                             
   Stomach, Glandular                                 (50)                      (46)                                                
   Tooth                                              (1)                       (1)                                                 
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (50)         (1)          (49)                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                             Page   2                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        CONTROL      112MG/KG     225MG/KG                                               
                                                   F             FEMALE       FEMALE                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Adrenal Gland, Cortex                              (48)                      (49)                                                
      Adenoma                                                                    1 (2%)                                             
   Adrenal Gland, Medulla                             (47)                      (48)                                                
   Islets, Pancreatic                                 (48)                      (46)                                                
      Adenoma                                          1 (2%)                                                                       
   Pituitary Gland                                    (48)         (7)          (50)                                                
      Pars Distalis, Adenoma                           8 (17%)      5 (71%)     10 (20%)                                            
      Pars Intermedia, Adenoma                         1 (2%)       1 (14%)                                                         
   Thyroid Gland                                      (49)                      (49)                                                
      Follicular Cell, Adenocarcinoma                                            1 (2%)                                             
      Follicular Cell, Adenoma                         1 (2%)                    1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   Ovary                                              (49)         (11)         (49)                                                
      Cystadenoma                                                                2 (4%)                                             
      Luteoma                                          2 (4%)                                                                       
      Teratoma                                                      1 (9%)                                                          
   Uterus                                             (50)         (36)         (50)                                                
      Leiomyoma                                        1 (2%)                                                                       
      Polyp Stromal                                    2 (4%)                    1 (2%)                                             
      Squamous Cell Carcinoma                                                    1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   Bone Marrow                                        (50)                      (50)                                                
      Hemangiosarcoma, Metastatic, Spleen              1 (2%)                                                                       
   Lymph Node                                         (50)         (7)          (50)                                                
      Hemangiosarcoma, Metastatic, Spleen              1 (2%)                                                                       
   Lymph Node, Mesenteric                             (47)         (6)          (48)                                                
   Spleen                                             (50)         (12)         (49)                                                
      Hemangiosarcoma                                  1 (2%)                                                                       
   Thymus                                             (43)         (1)          (39)                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                             Page   3                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        CONTROL      112MG/KG     225MG/KG                                               
                                                   F             FEMALE       FEMALE                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   Mammary Gland                                      (50)         (1)          (48)                                                
      Adenocarcinoma                                                1 (100%)     2 (4%)                                             
   Skin                                               (49)         (6)          (50)                                                
      Subcutaneous Tissue, Fibrosarcoma                1 (2%)                                                                       
      Subcutaneous Tissue, Mast Cell Tumor Benign      1 (2%)                                                                       
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   Bone                                               (50)                      (50)                                                
      Osteosarcoma                                     1 (2%)                                                                       
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   Brain                                              (49)                      (50)                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (50)         (7)          (49)                                                
      Alveolar/Bronchiolar Adenoma                                               1 (2%)                                             
      Alveolar/Bronchiolar Carcinoma                                3 (43%)                                                         
      Fibrosarcoma, Metastatic, Skin                   1 (2%)                                                                       
      Hepatocellular Carcinoma, Metastatic, Liver      1 (2%)                                                                       
      Osteosarcoma, Metastatic, Bone                   1 (2%)                                                                       
   Nose                                               (50)                      (50)                                                
      Papilloma                                                                  1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   Harderian Gland                                                              (3)                                                 
      Adenocarcinoma                                                             1 (33%)                                            
      Adenoma                                                                    1 (33%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   Kidney                                             (50)         (3)          (50)                                                
      Cortex, Adenoma, Tubular                         1 (2%)                                                                       
   Urinary Bladder                                    (48)                      (45)                                                
                                                             Page   4                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        CONTROL      112MG/KG     225MG/KG                                               
                                                   F             FEMALE       FEMALE                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 SYSTEMIC LESIONS                                                                                                                   
   Multiple Organs                                   *(50)        *(50)        *(50)                                                
      Lymphoma Malignant Histiocytic                                1 (2%)                                                          
      Lymphoma Malignant Lymphocytic                   4 (8%)       2 (4%)       2 (4%)                                             
      Lymphoma Malignant Mixed                        10 (20%)      5 (10%)      8 (16%)                                            
      Lymphoma Malignant Undifferentiated Cell        11 (22%)      4 (8%)      12 (24%)                                            
____________________________________________________________________________________________________________________________________
                                                                                                                                    
     *   Number of animals with any tissue examined microscopically                                                                 
                                                             Page   5                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE FEMALE                        CONTROL      112MG/KG     225MG/KG                                               
                                                   F             FEMALE       FEMALE                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
TUMOR SUMMARY                                                                                                                       
                                                                                                                                    
   Total Animals with Primary Neoplasms (b)            35          21          33                                                   
     Total Primary Neoplasms                           48          25          52                                                   
                                                                                                                                    
   Total Animals with Benign Neoplasms                 16           8          16                                                   
     Total Benign Neoplasms                            19           8          22                                                   
                                                                                                                                    
   Total Animals with Malignant Neoplasms              29          17          27                                                   
     Total Malignant Neoplasms                         29          17          30                                                   
                                                                                                                                    
   Total Animals with Metastatic Neoplasms              4                                                                           
     Total Metastatic Neoplasm                          7                                                                           
                                                                                                                                    
   Total Animals with Malignant Neoplasms                                                                                           
   Uncertain Primary Site                                                                                                           
                                                                                                                                    
   Total Animals with Neoplasms Uncertain-                                                                                          
   Benign or Malignant                                                                                                              
     Total Uncertain Neoplasms                                                                                                      
                                                                                                                                    
____________________________________________________________________________________________________________________________________
a  Number of animals examined microscopically at site and number of animals with lesion                                             
b  Primary tumors: all tumors except metastatic tumors                                                                              
                                                             Page   6                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          CONTROL      112MG/KG     225MG/KG                                               
                                                   M             MALE         MALE                                                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
DISPOSITION SUMMARY                                                                                                                 
  Animals Initially in Study                          60           60           60                                                  
  Scheduled Sacrifice                                 10           10           10                                                  
  Early Deaths                                                                                                                      
    Moribund                                           6            4            3                                                  
    Dead                                               6            3           12                                                  
    Accident                                           1                         1                                                  
  Survivors                                                                                                                         
    Terminal Sacrifice                                36           43           34                                                  
    Moribund                                           1                                                                            
  Animals Examined Microscopically                    50           50           50                                                  
                                                                                                                                    
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ALIMENTARY SYSTEM                                                                                                                  
                                                                                                                                    
   Esophagus                                          (50)                      (49)                                                
   Gallbladder                                        (41)                      (39)                                                
      Sarcoma, Metastatic, Epididymis                                            1 (3%)                                             
   Intestine Small                                    (50)         (5)          (50)                                                
   Intestine Small, Duodenum                          (47)         (2)          (43)                                                
   Intestine Small, Ileum                             (48)         (2)          (43)                                                
   Intestine Small, Jejunum                           (46)         (4)          (43)                                                
      Adenocarcinoma                                                             1 (2%)                                             
   Liver                                              (50)         (16)         (50)                                                
      Alveolar/Bronchiolar Carcinoma, Metastatic,                                                                                   
           Lung                                                     1 (6%)                                                          
      Carcinoma, Metastatic, Islets, Pancreatic                     1 (6%)                                                          
      Carcinoma, Metastatic, Pancreas                  1 (2%)                                                                       
      Hemangioma                                       1 (2%)                    1 (2%)                                             
      Hepatocellular Carcinoma                         6 (12%)      4 (25%)      3 (6%)                                             
      Hepatocellular Adenoma                           6 (12%)      6 (38%)      4 (8%)                                             
      Hepatocellular Adenoma, Multiple                              1 (6%)                                                          
   Pancreas                                           (50)                      (48)                                                
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
   Stomach, Forestomach                               (49)                      (46)                                                
      Squamous Cell Papilloma                          3 (6%)                    1 (2%)                                             
   Tooth                                              (6)                       (1)                                                 
      Odontoma                                         1 (17%)                                                                      
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                             Page   7                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          CONTROL      112MG/KG     225MG/KG                                               
                                                   M             MALE         MALE                                                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 CARDIOVASCULAR SYSTEM                                                                                                              
                                                                                                                                    
   Heart                                              (50)         (1)          (50)                                                
      Alveolar/Bronchiolar Carcinoma, Metastatic,                                                                                   
           Lung                                                     1 (100%)                                                        
      Sarcoma, Metastatic, Skin                        1 (2%)                                                                       
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 ENDOCRINE SYSTEM                                                                                                                   
                                                                                                                                    
   Adrenal Gland                                      (50)         (1)          (50)                                                
      Pheochromocytoma Benign                                       1 (100%)                                                        
   Adrenal Gland, Cortex                              (49)         (1)          (49)                                                
      Adenoma                                                                    1 (2%)                                             
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
   Adrenal Gland, Medulla                             (47)                      (49)                                                
      Pheochromocytoma Benign                                                    2 (4%)                                             
   Islets, Pancreatic                                 (50)         (1)          (47)                                                
      Carcinoma                                        1 (2%)       1 (100%)                                                        
   Pituitary Gland                                    (45)                      (50)                                                
      Pars Distalis, Adenoma                           1 (2%)                                                                       
   Thyroid Gland                                      (49)                      (50)                                                
      Follicular Cell, Adenoma                         1 (2%)                                                                       
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENERAL BODY SYSTEM                                                                                                                
                                                                                                                                    
   None                                                                                                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 GENITAL SYSTEM                                                                                                                     
                                                                                                                                    
   Epididymis                                         (50)                      (50)                                                
      Sarcoma                                                                    1 (2%)                                             
   Prostate                                           (49)                      (48)                                                
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
   Testes                                             (50)         (1)          (50)                                                
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 HEMATOPOIETIC SYSTEM                                                                                                               
                                                                                                                                    
   Bone Marrow                                        (50)                      (50)                                                
      Hemangiosarcoma, Metastatic, Spleen                                        1 (2%)                                             
   Lymph Node                                         (49)         (8)          (50)                                                
      Sarcoma, Metastatic, Skin                        1 (2%)                                                                       
      Axillary, Sarcoma, Metastatic, Skin                           1 (13%)                                                         
      Mediastinal, Alveolar/Bronchiolar Carcinoma,                                                                                  
                                                             Page   8                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          CONTROL      112MG/KG     225MG/KG                                               
                                                   M             MALE         MALE                                                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
HEMATOPOIETIC SYSTEM - cont                                                                                                         
           Metastatic, Lung                            1 (2%)                                                                       
      Pancreatic, Carcinoma, Metastatic, Pancreas      1 (2%)                                                                       
   Lymph Node, Mesenteric                             (48)         (5)          (50)                                                
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
   Spleen                                             (49)         (4)          (50)                                                
      Hemangioma                                                                 1 (2%)                                             
      Hemangiosarcoma                                                            1 (2%)                                             
   Thymus                                             (24)                      (35)                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 INTEGUMENTARY SYSTEM                                                                                                               
                                                                                                                                    
   Skin                                               (49)         (9)          (49)                                                
      Subcutaneous Tissue, Fibroma                     2 (4%)       1 (11%)                                                         
      Subcutaneous Tissue, Lipoma                      1 (2%)                                                                       
      Subcutaneous Tissue, Neurofibrosarcoma                                     1 (2%)                                             
      Subcutaneous Tissue, Sarcoma                     5 (10%)      5 (56%)      1 (2%)                                             
      Subcutaneous Tissue, Sarcoma, Multiple           1 (2%)                                                                       
      Subcutaneous Tissue, Sarcoma, Metastatic,                                                                                     
           Epididymis                                                            1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 MUSCULOSKELETAL SYSTEM                                                                                                             
                                                                                                                                    
   Skeletal Muscle                                    (1)          (3)                                                              
      Sarcoma                                                       1 (33%)                                                         
      Sarcoma, Metastatic, Skin                                     2 (67%)                                                         
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 NERVOUS SYSTEM                                                                                                                     
                                                                                                                                    
   Brain                                              (50)                      (50)                                                
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 RESPIRATORY SYSTEM                                                                                                                 
                                                                                                                                    
   Lung                                               (50)         (7)          (50)                                                
      Alveolar/Bronchiolar Adenoma                     5 (10%)      3 (43%)      5 (10%)                                            
      Alveolar/Bronchiolar Adenoma, Multiple                        1 (14%)      1 (2%)                                             
      Alveolar/Bronchiolar Carcinoma                   1 (2%)       2 (29%)                                                         
      Hepatocellular Carcinoma, Metastatic                          1 (14%)                                                         
      Hepatocellular Carcinoma, Metastatic, Liver      3 (6%)                                                                       
      Sarcoma, Metastatic, Skin                        1 (2%)       1 (14%)                                                         
   Trachea                                            (46)         (1)          (50)                                                
      Alveolar/Bronchiolar Carcinoma, Metastatic,                                                                                   
           Lung                                                     1 (100%)                                                        
____________________________________________________________________________________________________________________________________
                                                             Page   9                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          CONTROL      112MG/KG     225MG/KG                                               
                                                   M             MALE         MALE                                                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
                                                                                                                                    
 SPECIAL SENSES SYSTEM                                                                                                              
                                                                                                                                    
   Harderian Gland                                    (1)          (2)                                                              
      Adenoma                                          1 (100%)     2 (100%)                                                        
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 URINARY SYSTEM                                                                                                                     
                                                                                                                                    
   Kidney                                             (50)         (3)          (50)                                                
      Alveolar/Bronchiolar Carcinoma, Metastatic,                                                                                   
           Lung                                        1 (2%)       1 (33%)                                                         
      Sarcoma, Metastatic, Epididymis                                            1 (2%)                                             
      Renal Tubule, Adenoma                                                      1 (2%)                                             
   Urinary Bladder                                    (49)                      (48)                                                
      Hemangioma                                                                 1 (2%)                                             
____________________________________________________________________________________________________________________________________
                                                                                                                                    
 SYSTEMIC LESIONS                                                                                                                   
   Multiple Organs                                   *(50)        *(50)        *(50)                                                
      Lymphoma Malignant Lymphocytic                                1 (2%)                                                          
      Lymphoma Malignant Mixed                         2 (4%)       4 (8%)       2 (4%)                                             
      Lymphoma Malignant Undifferentiated Cell         2 (4%)       3 (6%)                                                          
____________________________________________________________________________________________________________________________________
                                                                                                                                    
     *   Number of animals with any tissue examined microscopically                                                                 
                                                             Page  10                                                               
NTP Experiment-Test: 05704-01  INCIDENCE RATES OF NEOPLASMS BY ANATOMIC SITE (SYSTEMIC LESIONS ABRIDGED) (a)      Report: PEIRPT05
Study Type: CHRONIC                                             RESORCINOL                                        Date: 09/18/94  
Route: GAVAGE                                                                                                     Time: 17:01:01  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
         B6C3F1 MICE MALE                          CONTROL      112MG/KG     225MG/KG                                               
                                                   M             MALE         MALE                                                  
____________________________________________________________________________________________________________________________________
                                                                                                                                    
TUMOR SUMMARY                                                                                                                       
                                                                                                                                    
   Total Animals with Primary Neoplasms (b)            33          29          22                                                   
     Total Primary Neoplasms                           40          36          28                                                   
                                                                                                                                    
   Total Animals with Benign Neoplasms                 21          15          15                                                   
     Total Benign Neoplasms                            22          15          18                                                   
                                                                                                                                    
   Total Animals with Malignant Neoplasms              18          19           9                                                   
     Total Malignant Neoplasms                         18          21          10                                                   
                                                                                                                                    
   Total Animals with Metastatic Neoplasms              7           5           2                                                   
     Total Metastatic Neoplasm                         10          10           9                                                   
                                                                                                                                    
   Total Animals with Malignant Neoplasms                                                                                           
   Uncertain Primary Site                                                                                                           
                                                                                                                                    
   Total Animals with Neoplasms Uncertain-                                                                                          
   Benign or Malignant                                                                                                              
     Total Uncertain Neoplasms                                                                                                      
                                                                                                                                    
____________________________________________________________________________________________________________________________________
a  Number of animals examined microscopically at site and number of animals with lesion                                             
b  Primary tumors: all tumors except metastatic tumors                                                                              
                                                             Page  11                                                               
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